Clinical Trials Sponsored by Disc Medicine, Inc

Total 745 results

Columbia University
Baylor College of Medicine; University of Pittsburgh; Boston Children's Hospital and other collaborators

Completed

Intranasal Dexmedetomidine Sedation in Children for Non-painful Procedures

Sedation | Dexmedetomidine

United States
University of California, Los Angeles
University of Colorado, Denver; Baylor College of Medicine; Albert Einstein College... and other collaborators

Not yet recruiting

Real-world Effectiveness of HPV Vaccine in Women Living With HIV and Its Impact on Cervical Cancer Screening Accuracies (LiVes-LLC)

Hiv | Hpv

United States
Memorial Sloan Kettering Cancer Center
Johns Hopkins University; M.D. Anderson Cancer Center; Dana-Farber Cancer Institute and other collaborators

Active, not recruiting

Molecular Studies and Clinical Correlations in Human Prostatic Disease

Prostate Cancer

United States
University of Alabama at Birmingham
National Institute of Mental Health (NIMH); Washington University School of... and other collaborators

Completed

Reaching 90 90 90 in Adolescents in Zambia: Using All Our SKILLZ (SKILLZ)

HIV Infections | Pregnancy Related | Mental Health Wellness 1 | STI

Zambia
Oncovir, Inc.
National Cancer Institute (NCI); University of Missouri-Columbia; Icahn School... and other collaborators

Completed

In Situ, Autologous Therapeutic Vaccination Against Solid Cancers With Intratumoral Hiltonol® (Poly-ICLC)

Melanoma | Sarcoma | Head and Neck Cancer | Non-Melanoma Skin Cancers

United States
DEKK-TEC, Inc.
National Cancer Institute (NCI); The University of Texas Health Science Center... and other collaborators

Completed

Study of 4-Demethyl-4-cholesteryloxycarbonylpenclome (DM-CHOC-PEN) in Patients With Brain Tumors (DM-CHOC-PEN)

Metastatic Malignant Neoplasm to Brain | Primary Brain Tumors

United States
Médecins Sans Frontières, France
Harvard Medical School (HMS and HSDM); Institute of Tropical Medicine, Belgium and other collaborators

Active, not recruiting

Evaluating Newly Approved Drugs in Combination Regimens for Multidrug-Resistant TB With Fluoroquinolone Resistance (endTB-Q) (endTB-Q)

Bacterial Infections | Gram-Positive Bacterial Infections | Tuberculosis | Tuberculosis, Multidrug-Resistant | Pulmonary Tuberculoses | Mycobacterial Infections

Vietnam, Pakistan, India, Kazakhstan, Lesotho, Peru
State University of New York at Buffalo
Children's Hospital of Philadelphia; University of Pennsylvania; United States... and other collaborators

Not yet recruiting

Exercise Reset for Concussion in a Military Environment

Brain Concussion
GlaxoSmithKline
PATH; Iqvia Pty Ltd; AMP (Agence de Médecine Préventive) (in French); RAFT (Réseau... and other collaborators

Completed

A Surveillance Study of Diseases Specified as Adverse Events of Special Interest, of Other Adverse Events Leading to Hospitalisation or Death, and of Meningitis in Children in Africa Prior to Implementation of the RTS,S/AS01E Candidate Vaccine

Malaria | Malaria Vaccines

Ghana, Burkina Faso, Kenya
Julieta Azevedo
Fundação para a Ciência e a Tecnologia; Centro Hospitalar e Universitário de... and other collaborators

Completed

Bi-REAL - DBT Skills Online Group Intervention for Bipolar Disorder (BI-REAL)

Bipolar Disorder

Portugal
Curonix LLC
Texas Institute for Pain and spine; Performance Pain and Sports Medicine PLLC; Holy Cross Hospital, Inc and other collaborators

Recruiting

Freedom-1 Study for Chronic Knee Pain

Osteoarthritic Knee Pain

United States
Baylor College of Medicine
University of California, Los Angeles; Oregon Health and Science University; Hospital... and other collaborators

Recruiting

BBD Longitudinal Study of Osteogenesis Imperfecta

Osteogenesis Imperfecta

United States, Canada
Washington University School of Medicine
University of Alabama at Birmingham; University of Chicago; The Cleveland Clinic and other collaborators

Completed

A Prospective Observational Study of Biopredictors of Bronchial Thermoplasty Response in Patients With Severe Refractory Asthma (BTR Study) (BTR)

Asthma

United States
Medical University Innsbruck
Barmherzige Brüder Vienna; Tiroler Landeskrankenanstalten GmbH (TILAK); Tiroler... and other collaborators

Completed

Post-Stroke Disease Management - Stroke Card (Stroke Card)

Stroke | Ischemic Attack, Transient | Cost-Benefit Analysis | Secondary Prevention | Disease Management

Austria
London School of Hygiene and Tropical Medicine
United States Agency for International Development (USAID); Population Services... and other collaborators

Completed

Double-blinded Trial of Household-based Chlorination in India

Diarrhoea

India
Institute of Tropical Medicine, Belgium
University of Manitoba; National Institute of Allergy and Infectious Diseases... and other collaborators

Recruiting

Monkeypox, Biology, Outcome, Transmission and Epidemiology -Prospective Follow-up of High-risk Contacts (MBOTE-CONTACT)

Mpox

Congo, The Democratic Republic of the
Eckehart SCHÖLL
Basel Academy for Quality and Research in Medicine; Prof. Dr. Werner Vach... and other collaborators

Recruiting

Accuracy of Sonography in Elbow Trauma (SONOELB)

Elbow Fracture | Elbow Sprain | Distal Humerus Fracture | Radial Head Fracture | Coronoid Process Fracture

Switzerland
Societatea Romana de Ultrasonografie in Medicina...
Institutul Regional de Gastroenterologie & Hepatologie Prof. dr. Octavian... and other collaborators

Unknown

Contrast Enhanced Ultrasound For The Evaluation Of Focal Liver Lesions (HepFocUS)

Liver Metastases | Focal Nodular Hyperplasia of Liver | Toxic Liver Disease With Focal Nodular Hyperplasia

Romania
Stanford University
Baylor College of Medicine; University of Iowa; Weill Medical College of Cornell... and other collaborators

Completed

Subtotal Resection of Large Acoustic Neuromas With Possible Stereotactic Radiation Therapy

Neuroma, Acoustic

United States
University of Cape Town
London School of Hygiene and Tropical Medicine; Fred Hutchinson Cancer Center; Aurum Institute and other collaborators

Unknown

The Correlate of Risk Targeted Intervention Study (CORTIS)

Tuberculosis

South Africa
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Completed

Pragmatic Clinical Trial for a More Effective Concise and Less Toxic MDR-TB Treatment Regimen(s) (TB-PRACTECAL)

Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa, Uzbekistan
Jie Li
Ministry of Science and Technology of the People´s Republic of China; Institute...

Unknown

Clinical Trial of Kanglaite Injection (KLTi) in Advanced Non-Small Cell Lung Cancer (NSCLC)

NSCLC

China
Waisenmedizin e. V. Promoting Access to Essential...
University of Freiburg; Waisenmedzin eV PACEM non-profit German NGO; German Medical... and other collaborators

Completed

Rationale for New Topical Anthroponotic Cutaneous Leishmaniasis (ACL) Treatment in Kabul (rtt-ACL)

Wound Healing

Afghanistan
University of Utah
Johns Hopkins University; University of Colorado, Denver; The Hospital for Sick... and other collaborators

Recruiting

HCRN Endoscopic Versus Shunt Treatment of Hydrocephalus in Infants (ESTHI)

Hydrocephalus

United States, Canada
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins University; Baylor College of Medicine; University of California... and other collaborators

Completed

Studies of the Ocular Complications of AIDS (SOCA)--HPMPC Peripheral CMV Retinitis Trial (HPCRT) (HPCRT)

HIV Infections | CMV Cytomegalovirus Retinitis
University of California, San Francisco
London School of Hygiene and Tropical Medicine; National Institute of Allergy... and other collaborators

Completed

Trial of Proactive Community Case Management to Reduce Child Mortality (Pro-CCM)

Access to Health Care | Under-five Child Mortality
Universidad de Antioquia
Barts and the London School of Medicine and Dentistry; Instituto Colombiano... and other collaborators

Completed

Optimal Strategy for the Management of ASCUS Cytology in Health Care Services of Medellin, Colombia (ASCUS-COL)

Cervical Cancer | Cervical Abnormalities | Cervical Intraepithelial Neoplasia Grade 2/3

Colombia
Hugo W. Moser Research Institute at Kennedy Krieger...
Baylor College of Medicine; New York University; National Institute of Neurological... and other collaborators

Active, not recruiting

Innovative Approaches to Gauge Progression of Sturge-Weber Syndrome

Sturge-Weber Syndrome

United States
Institute of Health Information and Statistics...
Charles University, Czech Republic; Institute for Clinical and Experimental... and other collaborators

Completed

COVID-19: Herd Immunity Study in the Czech Republic (SARSCoV2CZPrev)

SARS-CoV 2 | COVID

Czechia
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Active, not recruiting

PRACTECAL-PKPD Sub Study (PRACTECAL-PKPD)

Multi-drug Resistant Tuberculosis | Pulmonary Tuberculosis | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa
Mazonson & Santas Inc.
Icahn School of Medicine at Mount Sinai; ViiV Healthcare; AIDS Healthcare Foundation and other collaborators

Recruiting

Advancing Dignity, Health, and Optimism in Connection With Long Acting Injectables (ADHOC-LA)

HIV

United States
University of Colorado, Denver
The University of Texas Health Science Center, Houston; Bayer; Emory University; Rush University Medical Center and other collaborators

Completed

Joint Outcome Study Continuation for Children With Severe Factor VIII Deficiency (JOSC)

Hemophilia
Karl Landsteiner University of Health Sciences
NÖ Landesgesundheitsagentur, legal entity of University Hospitals in Lower... and other collaborators

Recruiting

Echocardiographic Predictors of Atrial Fibrillation (EPAF-7)

Atrial Fibrillation | Stroke, Ischemic | Embolic Stroke of Undetermined Source | TIA, Brain

Austria
Leiden University Medical Center
University of Edinburgh; Makerere University; Maastricht University; University... and other collaborators

Not yet recruiting

FRESHAIR4Life: Building the Case for Action

Tobacco Use | Pollution; Exposure | Non-communicable Disease
University of Oxford
Cambridge University Hospitals NHS Foundation Trust; Centre for Statistics... and other collaborators

Completed

Cytosponge™ for Post-Chemoradiation Surveillance of Oesophageal Cancer (CYTOFLOC)

Oesophageal Cancer

United Kingdom
Henry M. Jackson Foundation for the Advancement...
Johns Hopkins University; Karolinska Institutet; University of Miami; Chulalongkorn... and other collaborators

Active, not recruiting

Safety and Effects of Using Prime-boost HIVIS DNA and MVA-CMDR Vaccine Regimens With or Without Toll-like Receptor 4 Agonist on HIV Reservoirs in Perinatally HIV Infected Children and Youth (HVRRICANE)

HIV Infections

South Africa
Montreal Heart Institute
Institut de Recherches Cliniques de Montreal; Royal Victoria Hospital, Canada; Queen Elizabeth II Health Sciences Centre and other collaborators

Completed

A Study to Evaluate the Lipid Regulating Effects of 1-Methylnicotinamide (1-MNA)

Hypertriglyceridemia

Canada
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins University; Memorial Sloan Kettering Cancer Center; Baylor College... and other collaborators

Completed

Studies of the Ocular Complications of AIDS (SOCA)--Foscarnet-Ganciclovir CMV Retinitis Trial (FGCRT) (FGCRT)

HIV Infections | Cytomegalovirus Retinitis
SEAMEO Regional Centre for Food and Nutrition
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Recruiting

Egg Intervention During Pregnancy in Indonesia (PRECODE)

Protozoan Infections | Birth Weight | Weight Gain | Vitamin A Deficiency | Folate Deficiency | Zinc Deficiency | Child Development | Salmonella Infections | Anemia, Iron Deficiency | Fatty Acid Deficiency | Birth Length | B12 Deficiency Vitamin | Mineral Deficiency | E. Coli Infection | Shigella Infection | Amino Acid Deficiency and other conditions

Indonesia
National Cancer Institute (NCI)
M.D. Anderson Cancer Center; Washington University School of Medicine; Merck... and other collaborators

Completed

Phase I/II Adaptive Randomized Trial of Bevacizumab Versus Bevacizumab Plus Vorinostat in Adults With Recurrent Glioblastoma

Malignant Glioma | Recurrent Glioblastoma

United States
National Institute of Allergy and Infectious Diseases...
London School of Hygiene and Tropical Medicine; Institut National de la Santé... and other collaborators

Active, not recruiting

Partnership for Research on Ebola VACcinations (PREVAC)

Ebola Virus Disease

Guinea, Liberia, Mali, Sierra Leone
Odense University Hospital
Department of Cardiology, Odense University Hospital, Odense, Denmark.; Health... and other collaborators

Completed

Atrial Fibrillation, Prevention and Rehabilitation

Atrial Fibrillation | Rehabilitation | Prevention

Denmark
St. Justine's Hospital
University of Maryland, College Park; Tokyo Women's Medical University; Tokyo... and other collaborators

Enrolling by invitation

The Medical Management in Patients Exposed to Weapons of Mass Destruction (CBRNEObs)

Acute Respiratory Distress Syndrome | Medical Emergencies | Distress Respiratory Syndrome | Chemical Injury | Chemicals; Intoxication

Canada, France, Japan, United States
Public Health Foundation Enterprises, Inc.
National Institute on Drug Abuse (NIDA); Eunice Kennedy Shriver National Institute... and other collaborators

Completed

Comparison of Men's Prevention Apps to Research Efficacy (COMPARE)

Sexually Transmitted Diseases | HIV/AIDS | Risk Reduction | Pre-exposure Prophylaxis

United States
University of South Alabama
Mayo Clinic; Washington University School of Medicine; Tulane University Health... and other collaborators

Completed

A Novel Method of Screening for Ovarian Cancer Using Gynecologic Fluids and Mucus

Ovarian Cancer

United States
Prof Brian Lawlor
King's College London; Göteborg University; University College Dublin; Aristotle... and other collaborators

Completed

A Phase III Trial of Nilvadipine to Treat Alzheimer's Disease (NILVAD)

Alzheimer's Disease

Germany, Ireland, United Kingdom, France, Greece, Hungary, Italy, Netherlands, Sweden
Memorial Sloan Kettering Cancer Center
Johns Hopkins University; Massachusetts General Hospital; Fox Chase Cancer Center and other collaborators

Active, not recruiting

Does Cefoxitin or Piperacillin-Tazobactam Prevent Postoperative Surgical Site Infections After Pancreatoduodenectomy?

Pancreatic Cancer | Pancreatic Diseases | Pancreas Cancer

United States, Canada
University of Illinois at Urbana-Champaign
National Institute of Mental Health (NIMH); Baylor College of Medicine; University... and other collaborators

Recruiting

Intervention to Prevent Behavioral Health Symptoms Among Pandemic Affected Children

Emotional Distress | Prosocial Behavior | Pandemic, COVID-19 | Coping Skills | Social Support

United States
Johns Hopkins Bloomberg School of Public Health
University of Missouri-Columbia; Baylor College of Medicine; Washington University... and other collaborators

Completed

MethaCholine Bronchoprovocation Study (MeCIS) (MeCIS)

Asthma

United States
University of North Carolina, Chapel Hill
London School of Hygiene and Tropical Medicine; National Institute of Allergy... and other collaborators

Completed

Crowdsourcing A Public Health Campaign

HIV

Clinical Trials Sponsored by Disc Medicine, Inc

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