Search clinical trials for: Therapeutics

Total 7438 results

Abbott Nutrition

Completed

Tolerance of Healthy Term Infants Fed Infant Formulas #4

Healthy Term Infants

United States
Mateon Therapeutics

Completed

Study Evaluating the Safety and Response of Fosbretabulin in Asian Patients With Polypoidal Choroidal Vasculopathy (PCV)

Polypoidal Choroidal Vasculopathy

United States, Hong Kong, Korea, Republic of, Singapore, Taiwan
Mateon Therapeutics

Completed

Safety and Efficacy Study of Combretastatin A4 Phosphate to Treat Patients With Choroidal Neovascularization Secondary to Pathologic Myopia

Choroidal Neovascularization | Myopia, Degenerative
Mateon Therapeutics

Completed

Safety and Effectiveness of Combretastatin A-4 Phosphate Combined With Chemotherapy in Advanced Solid Tumors

Cancer | Tumor

United States
Mateon Therapeutics
Cancer Research UK

Completed

Safety Study of OXi4503 (a Vascular Disrupting Agent) Given by 3 x Weekly Intravenous Infusions to Patients With Advanced Solid Tumors

Solid Tumors

United Kingdom
Mateon Therapeutics

Completed

Safety Study of Increasing Doses of Combretastatin in Combination With Bevacizumab (Avastin) in Patients With Advanced Solid Tumors

Tumors

United Kingdom
Pervasis Therapeutics, Inc

Completed

Safety of Vascugel Treatment After Creation of Arteriovenous Access for Hemodialysis Use

Hemodialysis Access

United States
Baxter Healthcare Corporation
Halozyme Therapeutics

Completed

Study of Techniques of Subcutaneous Administration of Fluids Enabled by Human Recombinant Hyaluronidase (INFUSE-AT)

Dehydration

United States
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust; Medical Research Council

Completed

Mesenchymal Stem Cells in Multiple Sclerosis (MSCIMS) (MSCIMS)

Multiple Sclerosis

United Kingdom
Aeris Therapeutics

Completed

US 10 mL Biologic Lung Volume Reduction (BLVR) Phase 2 Emphysema Study

Pulmonary Emphysema

United States
Baxter Healthcare Corporation
Halozyme Therapeutics

Terminated

Study of In-line Pressure Using Various Techniques of Subcutaneous Administration of Fluids Enabled by Human Recombinant Hyaluronidase (INFUSE-AT1A) (INFUSE-AT1A)

Dehydration

United States
Aeris Therapeutics

Completed

Biologic Lung Volume Reduction (BLVR) Phase 2 Homogeneous Study

Homogeneous Emphysema

United States
Aeris Therapeutics

Completed

US Biologic Lung Volume Reduction (BLVR) Phase 2 Emphysema Study

Chronic Obstructive Pulmonary Disease | Pulmonary Emphysema

United States
DUSA Pharmaceuticals, Inc.

Completed

Light Dose Ranging Study of Photodynamic Therapy (PDT) With Levulan + Blue Light Versus Vehicle + Blue Light in Severe Facial Acne

Acne Vulgaris

United States
Aeris Therapeutics

Completed

A Dose Ranging Study of the Aeris Polymeric Lung Volume Reduction (PLVR) System in Patients With Advanced Upper Lobe Predominant Emphysema

Advanced Emphysema

Germany
Aeris Therapeutics

Completed

AeriSeal® System for Lung Volume Reduction in Patients With Advanced Emphysema

Lung Diseases | Pulmonary Emphysema | COPD

Israel
Halozyme Therapeutics

Completed

A Study of the Subcutaneous Injection of a Viscous Antibody Solution With Recombinant Human Hyaluronidase

Healthy
Myrexis Inc.

Completed

Safety Study of MPC-3100 in Cancer Patients Who Have Failed Other Treatments

Cancer

United States
Diamyd Therapeutics AB

Terminated

A Phase III Study to Investigate the Impact of Diamyd in Patients Newly Diagnosed With Type 1 Diabetes (EU)

Type 1 Diabetes Mellitus

France, Germany, Finland, Italy, Netherlands, Slovenia, Spain, Sweden, United Kingdom
Amsterdam Molecular Therapeutics
The Clinical Trial Company

Unknown

Study to Re-assess and Re-confirm Data Previously Recorded About the Incidence and Severity of Acute Abdominal "Pancreatitis" Episodes in Lipoprotein Lipase Deficient (LPLD) Subjects Previously Enrolled on AMT Clinical Studies

Lipoprotein Lipase Deficiency

Canada
Amsterdam Molecular Therapeutics
International Antiviral Therapy Evaluation Center

Unknown

Safety and Efficacy in LPL-Deficient Subjects of AMT-011, an Adeno-Associated Viral Vector Expressing Human Lipoprotein Lipase [S447X]

Familial Lipoprotein Lipase Deficiency

Canada
Amsterdam Molecular Therapeutics
The Clinical Trial Company

Completed

Efficacy and Safety of Human Lipoprotein Lipase (LPL)[S447X] Expressed by an Adeno-Associated Viral Vector in LPL-deficient Subjects

Familial Lipoprotein Lipase Deficiency

Canada
Stem Cell Therapeutics Corp.

Withdrawn

REGENESIS (US): A Phase IIb Prospective, Randomized, Double-blind, Placebo Controlled Study of NTx™-265: Human Chorionic Gonadotropin (hCG) and Epoetin Alfa (EPO) in Acute Ischemic Stroke Patients (REGENESIS)

Stroke

United States
CF Therapeutics Development Network Coordinating...
Cystic Fibrosis Foundation

Completed

Tolerability of Inhaled Hypertonic Saline in Infants With Cystic Fibrosis (ISIS Pilot)

Cystic Fibrosis

Canada, United States
Mateon Therapeutics

Completed

Safety Study of Increasing Doses of Combretasatin A1 Diphosphate (OXi4503) as Monotherapy in Subjects With Hepatic Tumor Burden (OXi4503)

Neoplasm Metastasis

Australia
Aestus Therapeutics
National Institute of Neurological Disorders and Stroke (NINDS); Symbiance,... and other collaborators

Completed

Study to Evaluate the Safety and Analgesic Activity of ATx08-001 in Subjects With Postherpetic Neuralgia

Postherpetic Neuralgia

United States
Acorda Therapeutics

Completed

Safety and Efficacy Study of Oral Fampridine-SR in Patients With Multiple Sclerosis

Multiple Sclerosis

United States, Canada
Pain Therapeutics

Completed

Dose Escalation and Safety Study of 188Re-PTI-6D2 in Patients With Metastatic Melanoma

Metastatic Melanoma

Israel
Pain Therapeutics

Completed

Safety Study of 188Re-PTI-6D2 in Patients With Metastatic Melanoma

Metastatic Melanoma

Israel
Aegera Therapeutics
Chinese University of Hong Kong

Completed

XIAP Antisense AEG35156 in Combination With Sorafenib in Patients With Advanced Hepatocellular Carcinoma (HCC)

Advanced Hepatocellular Carcinoma

China
Aegera Therapeutics

Terminated

AEG35156 in Combination With High-dose Cytarabine and Idarubicin in AML Following Failure of a Single Standard Dose Cytarabine Based Frontline Induction Regimen

Leukemia

United States, Canada, Germany
Aegera Therapeutics
The Leukemia and Lymphoma Society

Terminated

A Phase 1-2, Multicenter, Open-Label Study of AEG35156 in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia and Indolent B-Cell Lymphomas

Lymphoma, B-Cell | Leukemia, Lymphocytic, Chronic, B-Cell

Canada, United States
INSYS Therapeutics Inc

Completed

Liposome Encapsulated SN38 (LE-SN38) in Patients With Advanced Cancer

Neoplasms

United States
INSYS Therapeutics Inc

Completed

Study to Determine the Maximum Tolerated Dose of LErafAON in Patients With Advanced Cancer

Neoplasms

United States
INSYS Therapeutics Inc

Completed

Comparison of Liposome Entrapped Paclitaxel Easy to Use (LEP-ETU) and Taxol® Pharmacokinetics in Patients With Advanced Cancer

Neoplasm

United States, Germany, Netherlands
INSYS Therapeutics Inc

Completed

Liposome Encapsulated Docetaxel (LE-DT) in Patients With Solid Tumors (LE-DT)

Solid Tumors

United States
INSYS Therapeutics Inc

Completed

IL13-PE38QQR Infusion After Tumor Resection, Followed by Radiation Therapy With or Without Temozolomide in Patients With Newly Diagnosed Malignant Glioma

Glioblastoma Multiforme | Oligoastrocytoma | Anaplastic Astrocytoma

United States
INSYS Therapeutics Inc

Completed

Liposome Entrapped Paclitaxel Easy to Use (LEP-ETU) in Patients With Advanced Cancer

Neoplasm

United States
Sirion Therapeutics, Inc.

Completed

Study of Cyclosporine in the Treatment of Dry Eye Syndrome (ST-603-007)

Dry Eye Syndromes

United States
Sirion Therapeutics, Inc.

Completed

Study of Difluprednate in the Treatment of Inflammation Following Ocular Surgery (ST-601-004)

Inflammation

United States
Sirion Therapeutics, Inc.

Completed

Study of Cyclosporine in the Treatment of Dry Eye Syndrome (ST-603-005)

Dry Eye Syndromes

United States
Sirion Therapeutics, Inc.

Completed

Study of Difluprednate in the Treatment of Inflammation Following Ocular Surgery (ST-601-003)

Inflammation

United States
Ascenta Therapeutics

Completed

Safety and Efficacy Study of AT-101 in Combination With Docetaxel and Prednisone in Men With HRPC

Prostate Cancer

United States
Ascenta Therapeutics

Completed

Phase II Safety and Efficacy Study of Single-agent AT-101 in Patients With Relapsed or Refractory B-cell Malignancies

Follicular Lymphoma | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Diffuse Large Cell Lymphoma | Small Lymphocytic Lymphoma

United States
Bayhill Therapeutics

Completed

Phase 1 Study of BHT-3021 in Subjects With Type 1 Diabetes Mellitus

Hypoglycemia | Diabetes

Australia, United States, New Zealand
Bristol-Myers Squibb

Completed

Comparison Study of MDX-010 (CTLA-4) Alone and Combined With Docetaxel in the Treatment of Patients With Hormone Refractory Prostate Cancer

Prostate Cancer

United States
vTv Therapeutics

Completed

Safety Study of the Inhibition of Agouti-related Protein (AgRP) for the Management of Obesity and Weight Loss

Obesity

United States, Canada
Natrogen Therapeutics International, Inc

Unknown

Efficacy and Tolerability Study of Natura-Alpha in the Treatment of Patients With Active Ulcerative Colitis

Ulcerative Colitis

United States
vTv Therapeutics
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Left Ventricular Assist Device (LVAD) Specialized Centers of Clinically Orientated Research (SCCOR) Coagulation - Acute Intrinsic Pathway Antagonist (IPA)

Coagulation

United States
University of Washington
National Institute on Aging (NIA); ASCEND Therapeutics

Completed

Effect of Dihydrotestosterone (DHT) on Prostate Tissue [Short Title: DHT-3] (DHT-3)

Healthy

United States

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