Search clinical trials for: Phosphodiesterase Type 5 Inhibition

Total 78601 results

Otsuka America Pharmaceutical

Completed

Safety and Efficacy of Pletal (Cilostazol) for the Treatment of Juvenile Primary and Secondary Raynaud's Phenomenon

Raynaud's Disease

United States
Otsuka America Pharmaceutical

Completed

Safety and Efficacy of Pletal(Cilostazol) for the Treatment of Juvenile Primary and Secondary Raynaud's Phenomenon

Raynaud's Disease

United States
Corixa Corporation
GlaxoSmithKline

Unknown

Safety and Efficacy Study of Iodine-131 Anti-B1 Antibody for the Retreatment of Patients With Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma

United Kingdom, United States
Otsuka America Pharmaceutical

Completed

A Long-Term, Follow-On Safety Study of Four Doses of OPC-8212 (Vesnarinone) in HIV-Infected Persons

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of Zidovudine and T Lymphocyte Transfer in the Treatment of HIV Type III in Patients With AIDS

HIV Infections

United States
MediGene

Completed

Safety and Effectiveness Study of G207, a Tumor-Killing Virus, in Patients With Recurrent Brain Cancer

Glioma | Glioblastoma | Astrocytoma
National Center for Research Resources (NCRR)
University of Pennsylvania

Completed

Phase I Study of Ex Vivo Liver-Directed Gene Therapy for Familial Hypercholesterolemia

Familial Hypercholesterolemia
National Center for Research Resources (NCRR)

Completed

A Clinical Trial to Prevent the Complications of Insulin Resistance (Including Type-2 Diabetes)

Diabetes Mellitus | Insulin Resistance

United States
Sequus Pharmaceuticals

Completed

Randomized, Comparative Trial of DOX-SL (Stealth Liposomal Doxorubicin Hydrochloride) Versus Bleomycin and Vincristine in the Treatment of AIDS-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
Nexstar Pharmaceuticals

Completed

A Randomized Phase III Clinical Trial of Daunoxome Versus Combination Chemotherapy With Adriamycin/Bleomycin/Vincristine (ABV) in the Treatment of HIV-Associated Kaposi's Sarcoma.

HIV Infections | Sarcoma, Kaposi

United States
FeRx

Completed

Magnetic-Targeted Doxorubicin in Treating Patients With Cancer Metastatic to the Liver

Melanoma | Sarcoma | Stomach Neoplasms | Gastrointestinal Neoplasms | Breast Neoplasms | Lung Neoplasms | Liver Neoplasms | Colorectal Neoplasms | Pancreatic Neoplasms | Esophageal Neoplasms | Metastases, Neoplasm | Cholangiocarcinoma

United States, Germany
Anderson Clinical Research
Ligand Pharmaceuticals

Completed

A Study of ALRT 1057 Topical Gel in Patients With AIDS-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi
Pfizer

Completed

Study of the Safety and Efficacy of an Investigational Drug in Adult Patients With Multiple Myeloma

Multiple Myeloma

United States
Sequus Pharmaceuticals

Unknown

A Comparison of DOX-SL Versus Adriamycin Plus Bleomycin Plus Vincristine in the Treatment of Severe AIDS-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
Bayer

Completed

Phase III Randomized Double-Blind Placebo Controlled Study To Evaluate the Safety and Efficacy of Betaseron in AIDS and Advanced ARC Patients Receiving a Reduced-Dose AZT Regimen

HIV Infections

United States
Otsuka America Pharmaceutical

Completed

A Phase I Study of Three Doses of OPC-8212 (Vesnarinone) in HIV-Infected Persons With CD4+ Cell Number > 300 Cells/mm3

HIV Infections

United States
National Center for Research Resources (NCRR)

Unknown

Identification and Therapy Efficacy of Type 2 Diabetes in Hispanic Patients

Diabetes Mellitus, Non-Insulin-Dependent
Enzon Pharmaceuticals, Inc.

Terminated

Phase I Study of PEG-Paclitaxel In Patients With Advanced Solid Tumors & Lymphomas

Neoplasm Metastasis | Neoplasm | Lymphomas
Celgene Corporation

Completed

Study to Compare the Efficacy and Safety of Two CC-5013 Dose Regimens in Subjects With Metastatic Malignant Melanoma

Melanoma | Neoplasm Metastasis

United States, Canada
CancerVax Corporation

Unknown

Vaccine Therapy for Patients With Stage III Melanoma

Malignant Melanoma

United States, France, Australia, Canada, Germany, United Kingdom, Switzerland, Brazil, Ireland, Israel, Italy, Netherlands, New Zealand
CancerVax Corporation

Unknown

Vaccine Therapy for Patients With Stage IV Melanoma

Malignant Melanoma

United States, France, Australia, Canada, Germany, Switzerland, Brazil, Ireland, Israel, Italy, Netherlands, New Zealand, United Kingdom
Wentworth Area Health Services
Abbott

Unknown

Levosimendan Versus Dobutamine in Shock Patients

Septic Shock | Cardiogenic Shock

Australia
National Center for Research Resources (NCRR)
Duke University; Diabetes Trust Fund

Unknown

Screening Adolescents for Type 2 Diabetes Mellitus in a Community Clinic

Diabetes Mellitus

United States
Daiichi Pharmaceuticals

Completed

A Study of Tecogalan Sodium

HIV Infections | Sarcoma, Kaposi

United States
Medical Research Laboratories International

Terminated

Implitapide in Patients With Hypertriglyceridemia (HTG) on Maximal, Concurrent Triglyceride-Lowering Therapy

Hypertriglyceridemia

United States, Netherlands, Norway
Medical Research Laboratories International

Terminated

Implitapide in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) on Maximal Concurrent Lipid-Lowering Therapy

Familial Hypercholesterolemia

Netherlands, United States, Norway
National Center for Research Resources (NCRR)

Completed

NNC 90-1170 Mechanism of Action: A Double-Blind, Randomized, Single-Center, Placebo-Controlled, Crossover Study to Examine Beta-Cell Responsiveness to Graded Glucose Infusion in Subjects With Type 2 Diabetes

Diabetes Mellitus, Non-Insulin-Dependent

United States
Icahn School of Medicine at Mount Sinai

Completed

Study of Botulinum Toxin in Patients With Primary Hyperhidrosis

Hyperhidrosis

United States
National Center for Research Resources (NCRR)

Unknown

The Inhibition of Platelet Antiaggregating Activity of Clopidogrel by Atorvastatin Detected by Erythromycin Breath Test: a Metabolic Inhibition of Hepatic Cytochrome P450-3A

Thrombosis | Hypercholesterolemia

United States
National Center for Research Resources (NCRR)
Duke University

Unknown

Active Immunotherapy Of Metastatic Renal Cell Carcinoma Using Autologous Dendritic Cells Transfected With Autologous Total Tumor RNA

Renal Cell Carcinoma

United States
National Center for Research Resources (NCRR)
University of Michigan

Completed

Phase II Study of the Enzyme Inhibitor NTBC for Tyrosinemia Type I

Tyrosinemia, Type I
Melbourne Health

Completed

Using the Drug Spironolactone to Test If It Reduces Protein Leakage From the Kidney

Diabetic Nephropathy | Proteinuria | Glomerulonephritis | Kidney Disease

Australia
National Center for Research Resources (NCRR)

Completed

Tumor Lysate Pulsed-Dendritic Cell Vaccines After High-Dose Chemotherapy for Non-Hodgkin's Lymphoma

Lymphoma, Non-Hodgkin

United States
Fairview University Medical Center

Unknown

Study of Pulmonary Complications in Pediatric Patients With Storage Disorders Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Mucopolysaccharidosis I | Niemann-Pick Disease | Mucopolysaccharidosis VI | Wolman Disease | Adrenoleukodystrophy | Metachromatic Leukodystrophy | Pulmonary Complications | Fucosidosis | Globoid Cell Leukodystrophy | Gaucher's Disease | Mannosidosis | I Cell Disease

United States
Ribozyome

Completed

Gene Therapy in HIV-Positive Patients With Non-Hodgkin's Lymphoma

HIV Infections | Lymphoma, Non-Hodgkin

United States
Corixa Corporation
GlaxoSmithKline

Unknown

Safety and Efficacy Study of Iodine-131 Anti-B1 Antibody for Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

United States
Sequus Pharmaceuticals

Completed

Use of Stealth Liposomal Doxorubicin HCl ( DOX-SL ) in the Treatment of Moderate to Severe AIDS-Related Kaposi's Sarcoma.

HIV Infections | Sarcoma, Kaposi

United States
SUGEN

Completed

SU5416 in Patients With AIDS-Related Kaposi's Sarcoma Who Have Not Responded to Treatment

HIV Infections | Sarcoma, Kaposi

United States
National Center for Research Resources (NCRR)
Icahn School of Medicine at Mount Sinai

Completed

Genetic Study of Patients and Families With Diaphyseal Medullary Stenosis With Malignant Fibrous Histiocytoma of the Bone

Stenosis | Histiocytoma

United States
Anosys

Suspended

Immunotherapy With Autologous Dexosomes for Patients With Stage IV Melanoma

Melanoma
Daiichi Pharmaceuticals

Completed

A Phase I Trial of Tecogalan Sodium (DS-4152) Administered as an Infusion Every 21 Days

HIV Infections | Sarcoma, Kaposi

United States
DEKK-TEC, Inc.

Completed

Topical Use of 4,4'-Dihydroxybenzophenone-2,4-Dinitrophenylhydrazone (A-007) in the Treatment of Advanced Malignancies Including Kaposi's Sarcoma and Lymphoproliferative Disorders

HIV Infections | Lymphoproliferative Disorders | Sarcoma, Kaposi

United States
Corixa Corporation
GlaxoSmithKline

Unknown

Safety and Efficacy of Iodine-131 Anti-B1 Antibody for NHL Patients With Greater Than 25% Bone Marrow Involvement

Non-Hodgkin's Lymphoma

United States
ZonMw: The Netherlands Organisation for Health...
Boston Scientific Corporation

Completed

Emmy Trial: Uterine Artery Embolization (UAE) Versus Hysterectomy for Uterine Fibroids

Uterine Neoplasms | Leiomyoma | Menorrhagia

Netherlands
National Center for Research Resources (NCRR)

Unknown

Ingested Interferon Alpha: Prolongation or Permanence of the "Honeymoon" Phase in Newly Diagnosed Type 1 Diabetes Mellitus

Diabetes Mellitus, Type 1

United States
National Center for Research Resources (NCRR)

Unknown

CHP677: I-Metaiodobenzylguanidine (I-MIBG) Therapy for Refractory Neuroblastoma: a Phase II Study

Neuroblastoma

United States
Clinical Solutions

Completed

Photodynamic Therapy Clinical Trial For Cutaneous AIDS-Related Kaposi's Sarcoma Study Summary.

HIV Infections | Sarcoma, Kaposi

United States
National Center for Research Resources (NCRR)
University of Texas

Completed

Phase II Study of the Pathophysiology and Treatment With Enalapril and Polystyrene Sulfonate for Pseudohypoaldosteronism, Type I

Pseudohypoaldosteronism
Tularik

Unknown

Study of T900607-Sodium in Chemotherapy Naive Patients With Hepatocellular Carcinoma.

Hepatocellular Carcinoma

United States, China
Agouron Pharmaceuticals

Completed

A Pilot, Open-Label, Phase II, Randomized Study to Determine the Effects of Viracept on the Outcome of Cutaneous and Mucosal KS in AIDS Patients With CD4 <= 500 Cells/mm3

HIV Infections | Sarcoma, Kaposi

United States

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