Clinical Trials Sponsored by Leicester Royal Infirmary NHS Trust

Total 965 results

Our Lady's Hospice and Care Services
Royal Surrey County Hospital NHS Foundation Trust

Recruiting

Palliative Care and Oncology Survey on Terminology (POST)

Cancer

Ireland, United Kingdom
Royal Devon and Exeter NHS Foundation Trust
University of Plymouth; Plymouth Marjon University

Recruiting

Adapting Body Reprogramming for Severe Asthma: a Feasibility Study (BoBSA)

Severe Asthma

United Kingdom
Royal Free Hospital NHS Foundation Trust
Merck Sharp & Dohme LLC; University College, London

Completed

Immunophenotyping of Melanoma Patients on Treatment With Pembrolizumab (PASIP)

Melanoma | Neoplasms

United Kingdom
University College, London
Royal National Orthopaedic Hospital NHS Trust; Science & Technology Facilities...

Active, not recruiting

Development of a Non-invasive Assessment of Human Bone Quality Using Spatially Offset Raman Spectroscopy

Osteoarthritis | Osteoporosis | Osteogenesis Imperfecta | Rickets / Osteomalacia | Bone Infection
Royal Brompton & Harefield NHS Foundation Trust
University of Nottingham; GlaxoSmithKline; University College, London

Completed

Prospective Observation of Fibrosis in the Lung Clinical Endpoints Study (PROFILE)

Idiopathic Pulmonary Fibrosis | Idiopathic Non-specific Interstitial Pneumonitis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
University Hospital, Basel, Switzerland; Bioxydyn Ltd, Manchester

Unknown

MRI in Cystic Fibrosis and Primary Ciliary Dyskinesia

Cystic Fibrosis | Primary Ciliary Dyskinesia

United Kingdom
Royal Devon and Exeter NHS Foundation Trust
University of Plymouth; University of Exeter

Unknown

Comparison of SITA-Standard Compared to SITA-Fast Visual Fields.

Glaucoma
Royal College of Music
Imperial College London; Chelsea and Westminster NHS Foundation Trust

Completed

The Impact of Creative Interventions on Symptoms of Postnatal Depression

Depression, Postpartum

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
National Institute for Health Research, United Kingdom

Completed

Reliability of the 4 Metre Gait Speed in Idiopathic Pulmonary Fibrosis (IPFREL)

Idiopathic Pulmonary Fibrosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
National Institute for Health Research, United Kingdom

Completed

Implementation of Telemonitoring in Chronic Heart or Lung Failure (TELECRAFT)

Heart Failure | Respiratory Failure | COPD

United Kingdom
King's College London
King's College Hospital NHS Trust; Juvenile Diabetes Research Foundation; Guy... and other collaborators

Completed

Hypoglycaemia Awareness Restoration Programme (HARPdoc)

Hypoglycemia | Type 1 Diabetes Mellitus

United States, United Kingdom
University Hospital Southampton NHS Foundation...
Imperial College Healthcare NHS Trust; Royal Devon and Exeter NHS Foundation... and other collaborators

Completed

WT1 Immunity Via DNA Fusion Gene Vaccination in Haematological Malignancies by Intramuscular Injection Followed by Intramuscular Electroporation (WIN)

Leukaemia (Acute) | Leukaemia (Chronic) | Leukaemia (Acute Myeloid) | Leukaemia (Acute Lymphoblastic) | Leukaemia (Acute Promyelocytic)

United Kingdom
Royal Free Hospital NHS Foundation Trust
Massachusetts General Hospital; University College London Hospitals

Not yet recruiting

International Pancreatic Surgery Outcomes Study - PancreasGroup.Org

Pancreatic Neoplasms | Pancreatitis
University College, London
Royal Free Hospital NHS Foundation Trust; St. Bartholomew's Hospital; UCLH

Recruiting

COVID-19: Healthcare Worker Bioresource: Immune Protection and Pathogenesis in SARS-CoV-2 (COVID19-HCW)

Coronavirus Infections | Coronavirus | Immunological Abnormality | Health Care Worker Patient Transmission

United Kingdom
Royal Marsden NHS Foundation Trust
The Institute of Cancer Research, Sutton, Surrey, UK

Active, not recruiting

Prostate Advances in Comparative Evidence (PACE)

Prostate Cancer

New Zealand, Ireland, United Kingdom, Canada
Royal Brompton & Harefield NHS Foundation Trust
National Institute for Health Research, United Kingdom

Active, not recruiting

AI in PRImary Care Spirometry Pathways for Diagnosis of Lung Disease (APRIL) (APRIL)

Lung Diseases

United Kingdom
University Hospital Southampton NHS Foundation...
Royal Free and University College Medical School

Completed

Targeted Radiotherapy in HSCT for Poor Risk Haematological Malignancy

Lymphoma | Myeloma | Acute Leukaemia | Chronic Leukaemia

United Kingdom
Royal Marsden NHS Foundation Trust
Hoffmann-La Roche; Professor Cunningham's Clinical Research Fund

Completed

Combining Erlotinib Plus Bevacizumab and Gemcitabine Plus Capecitabine to Treat Advanced Pancreatic Cancer (TARGET)

Pancreatic Cancer

United Kingdom
Imperial College London
Swiss National Science Foundation; Royal Brompton & Harefield NHS Foundation...

Completed

Fluctuation of Airway Function in Children With Asthma

Asthma

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Abbott Medical Devices; Daiichi Sankyo Co., Ltd.

Terminated

Direct Angioplasty for Non ST Elevation Acute Coronary Events: DANCE Pilot Study (DANCE)

Acute Coronary Syndrome

United Kingdom
University College, London
King's College Hospital NHS Trust; University College London Hospitals; Guy's... and other collaborators

Recruiting

Legacies and Futures: Measuring Roles of Resilience and Vulnerability in Pregnancy and Birth Outcomes

Pregnancy Related

United Kingdom
University Hospitals of Derby and Burton NHS Foundation...
University of Nottingham; Northern Care Alliance NHS Foundation Trust; University... and other collaborators

Recruiting

Application of Functional Renal MRI to Improve Assessment of Chronic Kidney Disease (AFiRM)

Chronic Kidney Diseases

United Kingdom
King's College Hospital NHS Trust
University of Pennsylvania; Gilead Sciences; The Leeds Teaching Hospitals NHS... and other collaborators

Active, not recruiting

Genetic Determinants of Kidney Disease in People of African Ancestry With HIV (GEN-AFRICA)

Cardiovascular Diseases | Kidney Diseases | Obesity | Diabetes Mellitus | Genetic Predisposition to Disease | Kidney Injury | HIV Nephropathy

United Kingdom
Queen Mary University of London
Novartis Pharmaceuticals; University College, London; Barts & The London NHS... and other collaborators

Completed

Protective Role of Oxcarbazepine in Multiple Sclerosis (PROXIMUS)

Multiple Sclerosis

United Kingdom
North Bristol NHS Trust
University of Sheffield; University of Bristol; Newcastle University; University... and other collaborators

Unknown

Urodynamics for Prostate Surgery Trial; Randomised Evaluation of Assessment Methods (UPSTREAM)

Lower Urinary Tract Symptoms | Voiding Dysfunction | Detrusor Underactivity | Benign Prostate Obstruction

United Kingdom
British Cardiac Research Trust
Lund University; Royal Free Hospital NHS Foundation Trust; London North West... and other collaborators

Unknown

Progression of Coronary Atherosclerosis in Asymptomatic Diabetic Subjects (PROCEED)

Coronary Artery Disease | Type 2 Diabetes

United Kingdom
Imperial College London
Medical Research Council; University of Oxford; Guy's and St Thomas' NHS Foundation... and other collaborators

Completed

Research In Viral Eradication of HIV Reservoirs (RIVER)

HIV

United Kingdom
Royal Marsden NHS Foundation Trust
Wellcome Trust; Institute of Cancer Research, United Kingdom; Biomedical Research...

Completed

A Phase I, First in Man Study to Evaluate the Safety and Tolerability of a panRAF Inhibitor (CCT3833/BAL3833)in Patients With Solid Tumours (PanRAF)

Melanoma | Cancer

United Kingdom
Intensive Care National Audit & Research Centre
University of Oxford; Guy's and St Thomas' NHS Foundation Trust; University of... and other collaborators

Unknown

Renal Replacement Anticoagulant Management (RRAM)

Critical Illness

United Kingdom
Queen's University, Belfast
Medical Research Council; Belfast Health and Social Care Trust; NHS Lothian; University... and other collaborators

Completed

Clinimetric Properties of Outcome Measures in Bronchiectasis in the UK

Bronchiectasis

United Kingdom
Tara Mastracci
University Hospital, Lille; Skane University Hospital

Not yet recruiting

Longitudinal Registry of Endovascular Thoracoabdominal Aneurysms (LoRETA)

Aneurysm | Aortic Aneurysm
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust; Cancer Research UK

Active, not recruiting

UK Genetic Prostate Cancer Study: Epidemiology and Molecular Genetics Studies (UKGPCS)

Prostate Cancer

United Kingdom
Concr
Royal Marsden NHS Foundation Trust; Institute of Cancer Research, United Kingdom and other collaborators

Enrolling by invitation

VISION: Triple Negative Breast Cancer Sample and Clinical Data Acquisition Study

Triple Negative Breast Cancer | Cancer, Breast | Early-stage Breast Cancer

United Kingdom
Royal Marsden NHS Foundation Trust
AstraZeneca; Cancer Research UK; RM/ICR Biomedical Research Centre

Active, not recruiting

Phase I Study to Assess Safety of AZD6738 Alone and in Combination With Radiotherapy in Patients With Solid Tumours (Patriot)

Solid Tumour Refractory to Conventional Treatment

United Kingdom
Royal Marsden NHS Foundation Trust
Imperial College London; Institute of Cancer Research, United Kingdom

Active, not recruiting

Machine Learning in Myeloma Response (MALIMAR)

Myeloma

United Kingdom
University College, London
Medical Research Council; Royal Free Hospital NHS Foundation Trust; ViiV Healthcare

Completed

Adding MAraViroc &/or METformin for Hepatic Steatosis in People Living With HIV (MAVMET)

Hepatic Steatosis | HIV-1-infection

United Kingdom
Bournemouth University
Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust; Oomph! Wellness and other collaborators

Withdrawn

Effect of an Intervention on Health in Older Care Home Residents

Frail Elderly Syndrome | Frailty | Sedentary Behavior | Life Style Induced Illness | Lifestyle, Sedentary
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust; Cancer Research UK

Completed

Preoperative Imaging in Retroperitoneal Sarcoma (PIRS)

Cancer

United Kingdom
University of Exeter
U.S. Highbush Blueberry Council; Royal Devon University Healthcare NHS Foundation...

Recruiting

Dietary Supplementation With Blueberry in OA

Knee Osteoarthritis

United Kingdom
University Hospital Tuebingen
Royal Brompton & Harefield NHS Foundation Trust; National Heart and Lung Institute

Recruiting

Monocentric Registry to Investigate the Role of Platelet Function, Platelet Genetics, Proteomics and Metabonomics in Heart Disease (TuePIC)

Cardiovascular Disease

Germany
Royal Devon and Exeter NHS Foundation Trust
King's College London; Leiden University Medical Center

Completed

Type 1 Diabetes, Immunology, Genetics & Endogenous Insulin Production (TIGI)

Type 1 Diabetes Mellitus

Netherlands, United Kingdom
University of Edinburgh
Royal Free Hospital NHS Foundation Trust; National Health Service, United Kingdom

Active, not recruiting

The Effect of Varying Brightness on Palpebral Aperture

Eyelid Ptoses

United Kingdom
Royal Devon and Exeter NHS Foundation Trust
City, University of London; University of Exeter

Completed

PRediction of Outcome With ED Intervention for Colles Type Wrist Fractures [PREDICT] (PREDICT)

Colles' Fracture | Colles' Fracture of Unspecified Radius, Sequela

United Kingdom
Royal Marsden NHS Foundation Trust
Institute of Cancer Research, United Kingdom; Breakthrough Breast Cancer

Unknown

Rapid Medical Donation Programme for Breast Cancer (LEGACY)

Metastatic Breast Cancer

United Kingdom
Origin Sciences
Queen Mary University of London; Royal Devon and Exeter NHS Foundation Trust

Recruiting

Feasibility Study to Investigate Rectal Mucus in Aero-Digestive Tract Cancer. (ORI-EGI-03)

Pancreatic Cancer | Gastric Adenocarcinoma | Non Small Cell Lung Cancer | Bladder Cancer | Gall Bladder Cancer

United Kingdom
Royal Marsden NHS Foundation Trust
Institute of Cancer Research, United Kingdom; Onyx Therapeutics, Inc.

Completed

Phase I Trial of ONX-0801 Once Weekly or Alternate Weekly (ONX-0801)

Solid Tumours

United Kingdom
Nottingham University Hospitals NHS Trust
The Royal College of Surgeons of England; EIDO Healthcare

Completed

Multimedia Informed Consent & PROMs in Laparoscopic Cholecystectomy (EPICS)

Gallstone Disease

United Kingdom
GlaxoSmithKline
Quintiles, Inc.; Imperial College London; Royal Free Hospital NHS Foundation... and other collaborators

Completed

A Study to Evaluate the Safety of GSK2398852 When Co-administered With GSK2315698 in Patients With Systemic Amyloidosis

Amyloidosis

United Kingdom
Royal National Orthopaedic Hospital NHS Trust
Massachusetts General Hospital; Coxa, Hospital for Joint Replacement

Unknown

Analysis of Specimens From Patients With Orthopaedic Implants

Implants

United Kingdom
National Heart and Lung Institute
Royal Brompton & Harefield NHS Foundation Trust; British Heart Foundation

Completed

Cardiac Rehabilitation for the Treatment of Refractory Angina

Coronary Disease | Angina Pectoris

United Kingdom

Clinical Trials Sponsored by Leicester Royal Infirmary NHS Trust

Sponsors and Collaborators

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