Search clinical trials for: Massively-Parallel Sequencing

Total 1092 results

National University, Singapore
Health Promotion Board, Singapore; Genome Institute of Singapore A*Star, Singapore

Completed

Whole-exome Sequencing in Childhood Obesity

Childhood Obesity

Singapore
Gritstone bio, Inc.

Completed

A Study of Personalized Neoantigen Cancer Vaccines

Colorectal Cancer | Non Small Cell Lung Cancer | Gastroesophageal Adenocarcinoma | Pancreatic Ductal Adenocarcinoma | Urothelial Carcinoma

United States
Children's Hospital Medical Center, Cincinnati

Terminated

Malignant Hyperthermia Registry and Genetic Testing

Malignant Hyperthermia

United States
University Hospital, Montpellier
University Hospital, Toulouse; INRAE, Toulouse France; Université Paris-Saclay... and other collaborators

Completed

Ivermectin Neurotoxicity and ABCB1 Gene Mutations

DNA Sequencing

France
Texas Cardiac Arrhythmia Research Foundation

Unknown

Genetic Mechanisms Underlying SARS-CoV-2 Infection and the Impact of COVID-19 on Cognitive Function (GenCov)

Covid19

United States
Ambry Genetics
Beth Israel Deaconess Medical Center; HonorHealth Research Institute; University...

Completed

Utilizing a Multi-gene Testing Approach to Identify Hereditary Pancreatic Cancer

Pancreatic Ductal Adenocarcinoma

United States
Shanghai 10th People's Hospital

Unknown

Early Prevention Strategies of Severe Proliferative Vitreoretinopathy Base on Precision Diagnosis of Single Cell Sequencingvitreoretinopathy

Rhegmatogenous Retinal Detachment
University of Texas Southwestern Medical Center

Withdrawn

Altered Chemotherapy Sequencing During Neoadjuvant Therapy for Patients With Stage II or III Rectal Adenocarcinoma

Stage II Rectal Cancer | Stage III Rectal Cancer

United States
Imperial College London Diabetes Centre

Unknown

Application of UCPCR as a Testing Tool for Identification of MODY Patients in the UAE

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1 | Maturity-onset Diabetes of the Young

United Arab Emirates
Nanfang Hospital of Southern Medical University
Xiangya Hospital of Central South University; Beijing Ditan Hospital; RenJi Hospital and other collaborators

Unknown

Metagenomic Next-Generation Sequencing for Diagnosis of Ascites Infection in End-stage Liver Diseases

Ascites Infection

China
Cancer Institute and Hospital, Chinese Academy...

Completed

Target Gene Sequencing for Advanced Stage, Relapsed or Refractory Natural Killer/T-cell Lymphoma

Lymphoid Neoplasm

China
Ardigen
Małopolskie Centre of Entrepreneurship

Unknown

AImmune - Artificial Intelligence Algorithm for Identification of Immunogenic Neoepitopes of Cancer to Predict and Boost Patient's Response to Immunotherapies.

Non Small Cell Lung Cancer | Immunotherapy | Neoantigens | Neoepitopes | Next Generation Sequencing (NGS) | Personalized Neoantigen Cancer Vaccine

Poland
British Columbia Cancer Agency

Completed

Sequencing Abiraterone and Enzalutamide in mCRPC

Metastatic Castration-Resistant Prostate Cancer

Canada
Weill Medical College of Cornell University
Hamad Medical Corporation; Weill Cornell Medical College in Qatar

Terminated

Next Generation DNA Sequencing in Patients With Idiopathic Male Infertility

Infertility

Qatar
Centre Henri Becquerel

Unknown

Detection of Circulating Tumor DNA in p16- Locally Advanced Head Neck Squamous Cell Carcinoma (PERSO-NECK)

Head and Neck Squamous Cell Carcinoma

France
Centre Henri Becquerel

Unknown

Detection of Recurrent Mutations in Waldenström's Disease (DigiWAL)

Waldenstrom's Disease

France
Case Comprehensive Cancer Center

Withdrawn

Prevention of Recurrence and Metastasis in Genetically High-Risk Melanomas

Malignant Melanoma
Beijing Tiantan Hospital
Beijing Municipal Science & Technology Commission

Completed

Genetic Identification of Monogenic Disorders in Early-onset Stroke Using Targeted Next Generation Sequencing Panel (MDEOS)

Transient Ischemic Attack | Stroke, Acute | Single-gene Disorders

China
Centre Hospitalier Universitaire de Besancon

Completed

Molecular Diagnosis of Syndromic or Isolated Severe Intellectual Disability Using Whole Exome Sequencing : a Pilot Study (SHD-DI)

Severe Intellectual Disability

France
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

North Carolina Newborn Exome Sequencing for Universal Screening (NC_NEXUS)

Metabolism, Inborn Errors | Hearing Loss | Hereditary Disease

United States
Trakya University
Commission of Scientific Research Projects of Trakya University (TÜBAP)

Completed

Investigation of Supragingival Plaque Microbiome in Early Childhood Caries

Early Childhood Caries

Turkey
University Hospital, Rouen

Completed

Targeted Next-generation Sequencing Panel for Identification of Germline Mutations in Early Onset Cancers With Sporadic or Hereditary Presentation (PANEL)

Breast Cancer | Colorectal Cancer | Ovarian Cancer | Pediatric Cancers | Multiple Primary Malignant Tumours

France
Imperial College London Diabetes Centre

Unknown

Genetic Causes of Hypercholesterolaemia in the Emirati Population

Familial Hypercholesterolemia

United Arab Emirates
Imperial College London Diabetes Centre

Unknown

Genetic Causes of Gestational Diabetes in the Emirati Population

Gestational Diabetes | Maturity-onset Diabetes of the Young | GDM | MODY

United Arab Emirates
Nantes University Hospital

Completed

Prospective Multicenter Study on the Identification of Genetic Abnormalities Predisposing to Vasospasm From a Privileged Model: the Primary Raynaud's Phenomenon (RAY-GENE)

Primary Raynaud's Phenomenon (PR) | Genetic Mutations Causing PR | Study of Patients and Their Relatives (With or Without Primary PR)

France
Ajman University

Completed

Microbial Profiling in Pockets Related to Chronic Periodontitis Patients Using 16s RNA Metagenomics Sequencing

Periodontal Diseases

United Arab Emirates
Mansoura University

Completed

Fenofibrate Therapy in Pathological Unconjugated Hyperbilirubinemia in Full Term Infants

Neonatal Jaundice
Imperial College London
Imperial College Healthcare NHS Trust

Unknown

The FLIP-1 Study: Vaginal Lactobacillus Supplementation in Women at High Risk of Preterm Birth

Preterm Birth | Preterm Labor | Preterm Premature Rupture of Membrane | Cervical Incompetence | Miscarriage in Second Trimester | Miscarriage in Third Trimester

United Kingdom
Guangzhou Institute of Respiratory Disease
GeneCast Biotechnology Co., Ltd.

Unknown

Correlation Between Specific Gene Mutationand Local Immune Microenvironment and Immunotherapy Efficacy in NSCLC

NSCLC

China
Illumina, Inc.
Reprogenetics; Genesis Genetics

Completed

Single Embryo TrAnsfeR of Euploid Embryo (STAR)

Infertility | Aneuploidy

United States, Canada, Australia, United Kingdom
The First Affiliated Hospital with Nanjing Medical...

Unknown

Clinical Study of Gastric Cancer, Colorectal Cancer and Bladder Cancer Based on Liquid Biopsy

Gastric Cancer | Colorectal Cancer | Bladder Cancer

China
The First Affiliated Hospital with Nanjing Medical...
Fudan University

Unknown

A Study on Non-invasive Early Diagnosis of Gastrointestinal Stromal Tumors and Differentiation of Benign and Malignant Nodules

Gastrointestinal Stromal Tumor

China
National Human Genome Research Institute (NHGRI)

Completed

Adult Patients With Undiagnosed Conditions and Their Responses to Clinically Uncertain Results From Exome Sequencing

Undiagnosed Disease

United States
Cindy Cisneros

Completed

Development of a Non-invasive Prenatal Test

Pregnancy

United States
Cindy Cisneros

Completed

Non-Invasive Chromosomal Evaluation of 22q11.2 (22Q)

22q.11.2 Deletion/Duplication

Belgium
Cindy Cisneros

Completed

Non-Invasive Chromosomal Evaluation of Trisomy Study (NICHE)

Down Syndrome | Aneuploidy | Trisomy 21 | Trisomy 18 | Trisomy 13

United States
Cindy Cisneros

Completed

Development of a Prenatal Test for Fetal Aneuploidy Detection

Fetal Complications

United States
University Hospital, Bordeaux

Unknown

Identification Predictive Markers of Immunochemotherapy Response to the Primary Cutaneous Diffuse Large B Cell Lymphoma (PROTEOM)

Lymphoma, Large B-Cell, Diffuse

France
Istituto Scientifico Romagnolo per lo Studio e...
AUSL ROMAGNA

Unknown

Correlative Study on Cancer Patients and Healthcare Professionals Exposed to Infection by Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-Cov-2), COVID-19 Causative Agent. (CORSA)

COVID-19 | SARS-CoV-2

Italy
Nnamdi Azikiwe University

Completed

Effects of Lactobacillus Pentosus KCA1 on the Gut and Vaginal Microbiome of Women With Bacterial Vaginosis

Bacterial Vaginoses

Nigeria
Taipei Medical University Shuang Ho Hospital
Taipei Medical University; Delta Electronics

Unknown

Investigation of the Optimal Cocktailed Probiotics for Decolonization of Vancomycin-resistant Enterococci in Human Gut

Probiotics | Vancomycin-Resistant Enterococci

Taiwan
University Health Network, Toronto

Completed

Feasibility Clinical Study of Targeted and Genome-Wide Sequencing

Solid Tumors

Canada
Spanish Society of Thrombosis and Haemostasis
Francisco Vidal Pérez; Maria Fernanda López Fernández; Almudena Pérez Rodríguez; Irene Corrales Insa and other collaborators

Unknown

Molecular and Clinical Profile of Von Willebrand Disease in Spain (PCM-EVW-ES)

Von Willebrand Disease

Spain
Sir Run Run Shaw Hospital

Completed

Tracing MRSA in Households With Patients Infected With CA-MRSA by WGS

MRSA

China
University Hospital, Montpellier

Completed

Identification of Genes Involved in Juvenile Idiopathic Arthritis by Wholel Exome Sequencing (GenesinJIA)

Arthritis, Juvenile Rheumatoid
Ruijin Hospital

Unknown

A Metagenome-wide Association Study of Gut Microbiota in Gastrointestinal Non-Hodgkin's Lymphoma Patients

Gastrointestinal Lymphoma

China
University Hospital, Montpellier

Unknown

Dermatologic Patterns of Tuberous Sclerosis Patients and Somatic Mutation Relationship

Tuberous Sclerosis Complex

France
Leiden University Medical Center
Erasmus Medical Center; The Netherlands Cancer Institute; Medical Center Haaglanden and other collaborators

Unknown

Identifying Novel Variants in the DPYD Gene in Patients of Non-Western Descent (DPYD-NOW)

Neoplasms
Fudan University

Unknown

Next-generation Sequencing of Colorectal Cancer Somatic Cells to Guide Genetic Susceptibility Gene Mutations Screening.

Hereditary Colorectal Cancer

China
University Hospital, Strasbourg, France

Completed

Severe PID With Lymphoproliferation and Neutropenia (DICEP)

Primary Immune-Deficiency (PID) Common Variable Immune Deficiency (CVID)

France

Search clinical trials for: Massively-Parallel Sequencing

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