Search clinical trials for: single nucleotide polymorphisms

Total 9046 results

Abbott

Completed

Bioavailability of ABT-333 Tablet Versus First in Human (FIH) Capsule Formulation and Safety, Tolerability and PK Study of Single Doses of ABT-333 in Healthy Volunteers

HCV Infection

United States
University Medicine Greifswald

Completed

Pharmacokinetic and Pharmacodynamic Interactions Between the Cholesterol-lowering Ezetimibe and the Non-nucleoside Reverse Transcriptase Inhibitor Efavirenz During Chronic Treatment in Healthy Volunteers With Reference to Intestinal Expression of CYP3A4, UGT1A1, ABCB1 and ABCC2

Pharmacokinetics | Pharmacodynamics | Drug Interactions | Intestinal Transporter Expression

Germany
Neuraltus Pharmaceuticals, Inc.

Completed

Single-Ascending-Dose Safety/Tolerability of NP001 in Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

United States
GlaxoSmithKline

Completed

A Study Comparing Safety Of Abacavir And Lamivudine Administered Once-Daily As A Single Tablet Versus The Same Drugs Administered Twice-Daily As Separate Tablets (ALOHA Study)

HIV Infection

United States
Critical Biologics Corporation

Completed

Ascending Single Dose Study of Rhu-pGelsolin in Patients With Decreased Gelsolin Levels

Burns | Trauma | Infection | Low Gelsolin

Hong Kong
G. Hatzikosta General Hospital
University of Ioannina; Demokrition University of Thrace

Completed

Oxidative Stress in Standard Laparoscopic vs Single Port Cholecystectomy

Laparoscopy | Cholecystectomy | Uncomplicated Cholelithiasis | Standard Technique | Single Port Laparoscopy

Greece
AstraZeneca

Completed

Four-period Crossover Study to Assess the Effects of Single Oral Doses of ZD4054 (Zibotentan) (10mg and 30mg) on QTc Interval

Healthy

United Kingdom
National Heart, Lung, and Blood Institute (NHLBI)
Pediatric Heart Network

Completed

Trial of Angiotensin Converting Enzyme Inhibition in Infants With Single Ventricle--Pediatric Heart Network (ISV)

Heart Defects, Congenital | Heart Failure, Congestive

United States, Canada
Novartis

Completed

Safety and Tolerability of Single and Multiple Doses of VAK694 in Healthy and Atopic Subjects

Allergic Rhinitis

United States
Nantes University Hospital

Completed

Comparison of Antisecretory Effect of a Single Dose of Rabeprazole 20 mg and Omeprazole 20 mg in Obese Subjects (Oberab)

Gastroesophageal Reflux

France
ESBATech AG

Completed

Study of Intra-articular DLX105 Applied to Patients With Severely Painful Osteoarthritis of the Knee

Osteoarthritis

Germany, Switzerland
UConn Health
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institutes...

Completed

Pharmacokinetic Study of Single Dose Dutasteride in Healthy Subjects

Alcoholism | Alcohol Related Disorders | Alcohol Abuse

United States
Jerini Ophthalmic

Completed

A Phase 1 Safety Study of Single and Repeated Doses of JSM6427 (Intravitreal Injection) to Treat AMD

Macular Degeneration

United States
Amen Clinics, Inc.

Completed

Single Photon Emission Computed Tomography of the Normal Human Brain

Normal Human Subjects

United States
Pfizer

Completed

A Study To Evaluate The Safety, Tolerability And Plasma Drug Levels Following A Single Dose Of PF-04995274 In Healthy Adult Volunteers

Healthy

Belgium
AstraZeneca

Terminated

Oral AZD8165 After Single Oral Ascending Doses in Healthy Male Subjects

Thrombin Inhibition

United States
University Hospital, Antwerp

Completed

Open, Prospective Pilot Study to Obtain Aerosol Distribution in Asthmatic Patients Using Single Photon Emission Computed Tomography (SPECT) for Comparison With Functional Imaging Using Computer Methods

Asthma

Belgium
Hallym University Medical Center

Unknown

Intraocular Pharmacokinetics of Erythropoietin After Single Intravitreal Injection in Human

Pharmacokinetics | Erythropoietin

Korea, Republic of
Pfizer

Completed

Pharmacokinetics And Safety Study Of Two CP-690,550 Controlled Release Formulation Following Single Dose In Healthy Volunteers

Healthy

Singapore
Bristol-Myers Squibb

Completed

A Single Ascending Dose Study of BMS-650032 in HCV Infected Subjects

Chronic Hepatitis C

United States
AstraZeneca

Completed

A First Time in Man, Study to Assess the Safety of AZD8329 After Single Ascending Oral Doses

Healthy Men

Sweden
Pfizer

Completed

Phase1, Single Dose, Crossover Study to Determine Bioequivalence

Healthy

Singapore
Taipei Medical University WanFang Hospital

Unknown

An Open-label, Single Dose Pharmacokinetic Study of 14 mg Granisetron Patch in Healthy Subjects (Granisetron)

Cancer | Vomiting

Taiwan
Acrux DDS Pty Ltd

Completed

A Study to Evaluate the Potential for Interpersonal Transfer of Testosterone Following Single Dose Application

Hypogonadism

Australia
Actavis Inc.

Completed

Bioequivalence Study of Galantamine 4 mg Tablet and Reminyl Following a 4 mg Dose in Healthy Subjects Under Fed Conditions

Healthy

Canada
Sanofi
Bristol-Myers Squibb

Completed

Pharmacokinetic Study of Single Doses of Clopidogrel, 75 mg and 300 mg, in Healthy Subjects

Healthy

France
SkyePharma AG
Abbott

Completed

Single-dose Crossover Study to Evaluate the Early Bronchodilating Effect of FlutiForm HFA pMDI in Adult Subjects With Mild to Moderate Asthma

Mild to Moderate Asthma

United States
American Medical Systems

Unknown

MiniArc Study: Long-Term Effectiveness Trial for AMS Sling Systems (MiniArc)

Stress Urinary Incontinence in Women

United States
Seattle Children's Hospital

Unknown

Lumbar Plexus Catheter Versus Femoral Nerve Catheter for Postoperative Pain After Anterior Cruciate Ligament (ACL) Repair

Postoperative Pain

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of 2 mg Alprazolam OD Tablets Under Non-Fasting Conditions

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of 2 mg Alprazolam OD Tablets Under Fasting Conditions

Healthy

United States
National Institute of General Medical Sciences...

Unknown

Genetic Variation and Immune Responses After Injury

Pneumonia | Sepsis | Trauma | Burn | Injury

United States
Ascenta Therapeutics

Completed

A Study of Single-Agent AT-101 in Men With Hormone Refractory Prostate Cancer

Hormone Refractory Prostate Cancer

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Bupropion XL 150 mg Tablets Under Fasting Conditions

Healthy

United States
Pfizer
Bristol-Myers Squibb

Completed

A Single Dose Study Of PF-04620110 In Healthy Subjects

Healthy

Singapore
Shanghai Changzheng Hospital

Unknown

Single-Operator Versus Dual-Operator Double-balloon Endoscopy in Patients With Small-Bowel Disorders (DBE)

Small-Bowel Disorders

China
Pinnacle Health System

Completed

Demonstration of a New Device to Measure the Force of Delivering a Baby

Full Term Singleton Pregnancy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Citalopram 40 mg Tablets Under Fed Conditions

Healthy

Canada
Actavis Inc.

Completed

A Relative Bioavailability Study of Alprazolam 3 mg ER Tablets Under Fasting Conditions

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Fasting Conditions

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Oxycodone 5 mg / Ibuprofen 400 mg Tablets Under Non-fasting Conditions

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Glyburide/Metformin HCl 5 mg/500 mg Tablets Under Non-fasting Conditions

Healthy

United States
Actavis Inc.

Completed

The Dose-response Study of Topically Delivered Halobetasol Propionate Ointment in Normal Skin in Healthy Adult Subjects

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Metformin HCl 750 mg ER Tablets Under Fasting Conditions

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Glyburide/Metformin HCl 5 mg/500 mg Tablets Under Fasting Conditions

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Glyburide/Metformin HCl 5 mg/500 mg Tablets Under Fasting Conditions

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Citalopram 40 mg Tablets Under Fasting Conditions

Healthy

Canada
Actavis Inc.

Completed

A Limited Food Effect Study of Gabapentin 800 mg Tablets

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Alprazolam 3 mg Extended Release Tablets Under Non-fasting Conditions

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Propranolol HCl 160 mg Tablets Under Non-fasting Conditions

Healthy

United States

3

Subscribe