Search clinical trials for: comparative effectiveness research

Total 91479 results

National Center for Research Resources (NCRR)
Northwestern University; National Institute of Arthritis and Musculoskeletal...

Completed

Epidemiologic Study of Reproductive Outcome in Women With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
National Center for Research Resources (NCRR)
Northwestern University

Completed

Study of the Pathogenesis and Pathophysiology of Familial Neurohypophyseal Diabetes Insipidus

Diabetes Insipidus | Diabetes Insipidus, Neurohypophyseal

United States
Glaxo Wellcome

Unknown

A Study of Valacyclovir as Treatment for Genital Herpes Simplex Virus in HIV-Infected Patients

HIV Infections | Herpes Simplex | Herpes Genitalis

United States, Canada
Gilead Sciences

Completed

The Safety and Effectiveness of Zidovudine Plus Adefovir in HIV-Infected Patients

HIV Infections

United States
Abgenix
Immunex Corporation

Completed

ABX-EGF (a Monoclonal Antibody) Given to Patients With Prostate Cancer With or Without Tumor in Other Parts of the Body

Prostate Cancer

United States
National Institute on Drug Abuse (NIDA)
University of Vermont

Completed

Alternate-Day Buprenorphine Administration. Phase VII - 8

Opioid-Related Disorders

United States
National Center for Research Resources (NCRR)
University of Michigan

Completed

Hippocampal Complex Volume and Memory Dysfunction in Cushing's Syndrome

Cushing's Syndrome

United States
National Institute on Aging (NIA)

Completed

Study of Melatonin: Sleep Problems in Alzheimer's Disease

Dyssomnias | Alzheimer Disease

United States
VaxGen

Completed

Effectiveness of AIDSVAX B/E Vaccine in Intravenous Drug Users in Bangkok, Thailand

HIV Infections | HIV Seronegativity

Thailand
National Center for Research Resources (NCRR)
University of Texas

Unknown

Genetic Study of the FBN1 Gene and Fibrillin-1 Abnormalities in Choctaw Native Americans and Other Patients With Systemic Sclerosis

Systemic Sclerosis

United States
National Center for Research Resources (NCRR)
University of Michigan

Completed

Pilot Study of the Effect of Baclofen and Bromocriptine on Luteinizing Hormone Secretion in Pubertal Children

Growth Disorders
Dupont Merck

Completed

A Study of Indinavir Taken With or Without DMP 266

HIV Infections

Puerto Rico, United States, Canada
U.S. Bioscience
Jacobus Pharmaceutical

Completed

Randomized Phase I Study of Trimetrexate Glucuronate (TMTX) With Leucovorin (LCV) Protection Plus Dapsone Versus Trimethoprim / Sulfamethoxazole (TMP/SMX) for Treatment of Moderately Severe Episodes of Pneumocystis Carinii Pneumonia

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
National Center for Research Resources (NCRR)
University of Rochester

Completed

Phase II Pilot Controlled Study of Short Vs Longer Term Pimozide (Orap) Therapy in Tourette Syndrome

Tourette Syndrome
Peptimmune

Completed

Safety Study of PI-0824 to Treat Pemphigus Vulgaris

Pemphigus Vulgaris

United States
Astra USA

Completed

An Open Study of Foscarnet Treatment First Episode CMV-Retinitis in AIDS Patients

HIV Infections | Cytomegalovirus Retinitis

United States
National Center for Research Resources (NCRR)

Completed

Pharmacokinetic and Pharmacodynamic Interaction Study of Digoxin and Hawthorn

Heart Diseases

United States
National Center for Research Resources (NCRR)
Johns Hopkins University; National Institute of Neurological Disorders and...

Completed

Phase III Randomized Controlled Study of Morphine and Nortriptyline in the Management of Postherpetic Neuralgia

Pain | Herpes Zoster
National Center for Research Resources (NCRR)
Stanford University

Completed

A Maintenance Extension of Phase I Pilot Study of Chimeric Anti-CD4 Antibody M-T412 in Patients With Multiple Sclerosis

Multiple Sclerosis
National Center for Research Resources (NCRR)

Unknown

Study of the Farnesyl Transferase Inhibitor, R115777, in Combination With Topotecan (NYU 99-32)

Cancer

United States
National Center for Research Resources (NCRR)

Unknown

Ingested Interferon Alpha: Prolongation or Permanence of the "Honeymoon" Phase in Newly Diagnosed Type 1 Diabetes Mellitus

Diabetes Mellitus, Type 1

United States
Immunobiology Research Institute

Completed

A Study of Thymopentin Effects on HIV-1 Infectivity of Blood Mononuclear Cells and Semen in HIV Infected Patients

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of Combivir Plus Abacavir Plus 141W94 in Patients Who Previously Have Used Anti-HIV Drugs

HIV Infections

United States
National Center for Research Resources (NCRR)
University of California, Los Angeles

Completed

Study of the Effect of Four Methods of Cardiopulmonary Resuscitation Instruction on Psychosocial Response of Parents With Infants at Risk of Sudden Death

Pulmonary Hypertension | Respiratory Distress Syndrome | Bronchopulmonary Dysplasia
National Center for Research Resources (NCRR)
University of Virginia

Completed

Randomized Study of Decreased Hyperinsulinemia on the Ovulatory Response to Clomiphene Citrate in Women With Polycystic Ovary Syndrome

Polycystic Ovary Syndrome | Hyperinsulinism

United States, Italy
National Center for Research Resources (NCRR)
HRSA/Maternal and Child Health Bureau

Completed

Does Lead Burden Alter Neuropsychological Development?

Lead Poisoning

United States
National Center for Research Resources (NCRR)
University of Texas

Completed

Study of the Pathogenesis of Porphyria Cutanea Tarda

Porphyria Cutanea Tarda

United States
National Center for Research Resources (NCRR)

Unknown

CHP677: I-Metaiodobenzylguanidine (I-MIBG) Therapy for Refractory Neuroblastoma: a Phase II Study

Neuroblastoma

United States
Celgene Corporation

Completed

A Phase II, Parallel Group, Randomized, Placebo-Controlled Study of the Safety and Efficacy of Thalidomide in Reducing Weight Loss in Adults With HIV Wasting Syndrome

HIV Infections | HIV Wasting Syndrome

United States
National Center for Research Resources (NCRR)
Yale University

Completed

Phase II Pilot Study of Octreotide, a Somatostatin Octapeptide Analog, for Gastrointestinal Hemorrhage in Hormone-Refractory Hereditary Hemorrhagic Telangiectasia and Senile Ectasia

Hereditary Hemorrhagic Telangiectasia | Ectasia
Aronex Pharmaceuticals

Unknown

A Safety and Effectiveness Study of Aroplatin in Patients With Advanced Colorectal Cancer Resistant to Standard Therapies

Colorectal Neoplasms

United States
Immunobiology Research Institute

Completed

Double Blind Study of Thymopentin Effects on Patients With HIV-1 Infection

HIV Infections

United States
Hoffmann-La Roche

Completed

An Open-Label, Multicenter Study to Evaluate the Safety and Tolerability of Dideoxycytidine (ddC) in Patients With AIDS or Advanced ARC Who Previously Demonstrated Intolerance to Zidovudine (AZT) in Protocol N3300 or N3492

HIV Infections

United States
HEM Research

Completed

A Multicenter, Double-Blind, Controlled Study to Evaluate Ampligen

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of Retrovir in the Treatment of Psoriasis in HIV-Positive Patients

HIV Infections | Psoriasis

United States
Alkermes, Inc.

Completed

The Safety and Effectiveness of RMP-7 Plus Amphotericin B in Patients With HIV and Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States
National Center for Research Resources (NCRR)
University of Texas

Completed

Phase II Study of the Pathophysiology and Treatment With Enalapril and Polystyrene Sulfonate for Pseudohypoaldosteronism, Type I

Pseudohypoaldosteronism
National Center for Research Resources (NCRR)
University of Pittsburgh

Completed

Pilot Study of Vestibular Rehabilitation Training for Panic Disorder With Vestibular Dysfunction

Vestibular Diseases | Panic Disorder | Agoraphobia
National Center for Research Resources (NCRR)
University of Alabama at Birmingham

Completed

Randomized Study of Oral Contraceptives or Hormone Replacement Therapy in Women With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States
Aronex Pharmaceuticals

Completed

Safety and Effectiveness of Zintevir (AR177) Given to HIV-Infected Patients

HIV Infections

United States
National Center for Research Resources (NCRR)
University of California, Los Angeles; National Institute of Neurological Disorders...

Completed

Phase II Randomized Study of Early Surgery Vs Multiple Sequential Antiepileptic Drug Therapy for Infantile Spasms Refractory to Standard Treatment

Epilepsy | Spasms, Infantile
RespireRx
FRAXA Research Foundation

Completed

Effects of CX516 on Functioning in Fragile X Syndrome and Autism

Fragile X Syndrome | Autism

United States
National Center for Research Resources (NCRR)
Northwestern University

Completed

Phase II/III Randomized, Double-Blind, Placebo-Controlled Study of Dehydroepiandrosterone in Women With Mild to Moderate Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
National Center for Research Resources (NCRR)
Columbia University

Unknown

Measurement of Outcome of Surgical Treatment in Patients With Acromegaly

Acromegaly

United States
Janssen, LP

Completed

A Study of Itraconazole in the Prevention of Histoplasmosis, a Fungal Infection, in HIV-Infected Patients

HIV Infections | Histoplasmosis

United States
Pfizer

Completed

A Study to Evaluate the Safety and Efficacy of Azithromycin in Individual Patients With Serious Nontuberculous Mycobacterial Disease Who Are Failing or Intolerant of Other Available Therapy

HIV Infections | Mycobacterium Avium-Intracellulare Infection | Tuberculosis, Mycobacterium Infection

United States
National Center for Research Resources (NCRR)
Children's Hospital of Philadelphia

Completed

Diagnostic Pilot Study of Dual Energy Absorptiometry in the Detection of Osteopenia or Osteoporosis in Patients With Thalassemia Major

Osteoporosis | Osteopenia | Thalassemia Major
Glaxo Wellcome

Completed

A Study of 1592U89 Combined With Other Anti-HIV Drugs in Patients Who Have Taken Anti-HIV Drugs

HIV Infections

United States
National Center for Research Resources (NCRR)
University of Pennsylvania

Completed

Randomized Study of Growth Hormone on Bone Mineral Density in Patients With Adult Onset Growth Hormone Deficiency

Osteoporosis | Growth Hormone Deficiency

United States
National Center for Research Resources (NCRR)
University of Texas

Completed

Phase I/II Study of Heme Arginate and Tin Mesoporphyrin for Acute Porphyria

Porphyria

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