Search clinical trials for: single nucleotide polymorphism

Total 9653 results

Assaf-Harofeh Medical Center

Unknown

Anterior Cruciate Ligament (ACL) Reconstruction: Single Bundle Versus Double Bundle

Anterior Cruciate Ligament Tear
AstraZeneca

Completed

Study to Investigate the Activity of AZD5122 When Given as a Single Dose to Healthy Male Subjects

Healthy

United Kingdom
Eli Lilly and Company
Gynecologic Oncology Group

Completed

A Study of Single Agent Pemetrexed Disodium in Treating Patients With Recurrent or Persistent Ovarian or Primary Peritoneal Cancer

Ovarian Cancer | Peritoneal Cancer

United States
Marilia Medicine School

Completed

Pterygium Treatment Using Single Beta-therapy as Adjuvant Treatment Compared to Conjunctival Autograft

Pterygium

Brazil
Resolvyx Pharmaceuticals, Inc

Completed

Single and Multiple Ascending Oral Dose Study of RX-10001 in Healthy Volunteers

Healthy

Netherlands
AstraZeneca

Terminated

Open-Label Absorption, Distribution, Metabolism, Excretion (ADME) and Pharmacokinetics (PK) Following a Single Oral Dose of AZD1236 in Healthy Male Subjects

Healthy

United Kingdom
Cordis Corporation

Completed

Double or Single Dose Sirolimus-Eluting Stents in Diabetic Patients With de Novo Coronary Artery Lesions (3D)

Coronary Artery Disease

Brazil
University of Salzburg
Biolitec Pharma Ltd.

Unknown

Single-arm Study of Photodynamic Laser Therapy Using Foscan for Non-curatively-resectable Bile Duct Carcinoma

Non-curative Resectable Bile Duct Carcinoma

Austria, Germany
University Hospital, Gasthuisberg

Completed

Single-probe Microwave Ablation (MWA) of Metastatic Liver Cancer (LiverMWA1)

Liver Neoplasms

Belgium
AstraZeneca

Terminated

AZD5985 Single Ascending Dose Study

Healthy

Sweden
Gyeongsang National University Hospital

Completed

Adjunctive Cilostazol Versus High Maintenance-dose ClopidogrEL in Acute Myocardial Infarction (AMI) Patients According to CYP2C19 Polymorphism (ACCELAMI2C19)

Myocardial Infarction

Korea, Republic of
Moberg Pharma AB

Completed

Assessment of the Effects on Barrier Impairment, Clinical Features and Bacterial Colonization of Topical Formulations in Patients With Atopic Eczema; a Phase IIa, Single-center, Randomized, Observer-blind Study

Atopic Dermatitis

Germany
V.K.V. American Hospital, Istanbul

Terminated

Single Dose Gonadotropin-releasing Hormone (GnRH) Agonist Administration in the Luteal Phase of GnRH Antagonist Stimulated ICSI-ET Cycles

Infertility

Turkey
National Taiwan University Hospital

Completed

Correlation of Genetic Polymorphism and Livedo Vasculitis

Livedo Vasculitis | Livedoid Vasculitis | Livedoid Vasculopathy | Genetic Pleomorphism | Leiden Mutation

Taiwan
University of Vermont
St. Louis University

Completed

Safety Study of Nifurtimox for Relapsed or Refractory Neuroblastoma

Neuroblastoma

United States
SocraTec R&D GmbH
SocraMetrics GmbH

Completed

Nifedipine Bioavailability Study With Oral Single Doses Under Fasting and Fed Conditions

Bioavailability, Therapeutical Indication Not Studied

Germany
Cervical Artery Dissections and Ischemic Stroke...

Unknown

Looking For Genetic and Environmental Risk Factors and Therapeutic Aspects in Cervical Artery Dissections (CADISP)

Stroke | Brain Infarction | Cervical Artery Dissection

Argentina, Belgium, Finland, France, Germany, Italy, Switzerland, Turkey, United Kingdom
Interleukin Genetics, Inc.

Completed

Association of Genes to Resistance to Weight Loss in Obese Patients

Obesity | Metabolic Syndrome | Dyslipidemia

United States
Chonnam National University Hospital
Institute of Bioequivalence and Bridging Study, College of Pharmacy, CNU

Completed

Bioequivalence of Rebamipide in Korean

Pharmacogenetics | Therapeutic Equivalency

Korea, Republic of
Uppsala University

Completed

Single-photon Emission Computed Tomography (SPECT) to Predict Peritoneal Chemotherapy

Peritoneal Carcinomatosis

Sweden
Amgen

Completed

A Study of Repeat-Dose Subcutaneous Darbepoetin Alfa in Subjects With Congestive Heart Failure and Anemia, and a Single Dose in Healthy Age- and Sex-Matched Control Subjects

Anemia | Congestive Heart Failure
Pfizer

Completed

A First In Human Study To Evaluate The Safety, Tolerability And Pharmacokinetics Of PF-04455242 In Single Rising Doses In Healthy Adult Volunteers

Bipolar Depression

United States
Baskent University

Completed

Single Lumen Needle Without Flushing or Double Lumen Needle With Follicle Flushing in Oocyte Retrieval

Oocyte Retrieval

Turkey
Baskent University

Completed

Double and Single Intrauterine Insemination In Controlled Ovarian Stimulation (COH) Cycles With Multifollicular Development

Infertility

Turkey
Pfizer

Completed

A Phase I, Single IV Dose Of PF-04360365 In Adults With Mild To Moderate Alzheimer's Disease

Alzheimer's Disease

Canada, United Kingdom, Australia, Sweden
LenSx Lasers Inc.

Completed

A Prospective Single Center Clinical Study for Capsulotomy Using the LenSx 550 Laser

Cataract

Hungary
Enanta Pharmaceuticals, Inc

Completed

Safety and Pharmacokinetics of Ascending Single Oral Doses of EDP-322 in Nonfasting and Fasting Healthy Volunteers

Methicillin-resistant Staphylococcus Aureus | Skin and Soft Tissue Infections

United States
Radboud University Medical Center

Completed

A Possible Therapeutic Role for Adenosine During Inflammation

Endotoxemia

Netherlands
AstraZeneca

Completed

Study to Investigate Safety, Tolerability and Pharmacokinetics With Single and Multiple Ascending Doses of AZD1446

Healthy

Sweden
AstraZeneca

Completed

AZD9164 Single Ascending Dose Study in Healthy Male Subjects

Healthy

Sweden
ORA, Inc.

Completed

A Single-Center Evaluation of the Pattern of Allergic Signs and Symptoms During 4 Weeks in Ragweed Season

Allergic Conjunctivitis

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Single Doses of ILV-095 in Healthy Subjects

Healthy Subjects

United States
Mylan Pharmaceuticals Inc

Completed

Single-Dose Fed Bioequivalence Study of Nisoldipine Extended-Release Tablets (40 mg; Mylan) and Sular® Extended-Release Tablets (40 mg; First Horizon) in Healthy Volunteers

Healthy

United States
Amersham Buchler, GmbH & Co KG
The Cleveland Clinic; Beacon Bioscience, Inc.; CRL, Medinet Europe, Breda, The... and other collaborators

Completed

A Study of Gadodiamide Injection in Myocardial Perfusion Magnetic Resonance Imaging (MR-IMPACT-II)

Coronary Artery Disease
Xenon Pharmaceuticals Inc.

Completed

Single and Multiple Ascending Dose Safety Study of XPF-001 in Healthy Volunteers

Healthy Human Volunteers

Canada
AstraZeneca

Completed

AZD6088 Single Ascending Dose Study

Healthy Volunteers

United Kingdom
Link Medicine Corporation

Completed

A Double-Blind, Placebo Controlled, Single, Escalating Dose Study to Evaluate the Preliminary Pharmacokinetics, Safety and Tolerability of LNK-754 in Healthy Elderly Volunteers

Healthy Elderly Volunteers

United States
Korea University Anam Hospital
Korea University

Unknown

CYP19 Genetic Polymorphism & Aromatase Inhibitor(AI) (AI-CYP19)

Breast Neoplasms | Arthritis | Arthralgia | Genetic Polymorphism

Korea, Republic of
Vanak Eye Surgery Center

Completed

Ahmed Glaucoma Valve and Single-Plate Molteno Implants in Treatment of Refractory Glaucoma

Refractory Glaucoma

Iran, Islamic Republic of
Ankara University

Unknown

VKORC1 and CYP2C9 Gene Polymorphisms and Warfarin Management

Atrial Fibrillation | Peripheral Vascular Disease | Deep Vein Thrombosis | Pulmonary Embolism | Cardiac Thrombus | Heart Valve Replacement (Mechanical or Biological With AF) | Cardiomyopathy (Ischemic or Dilated)

Turkey
University Hospital, Limoges

Completed

Diagnostic of Lewy Body Dementia by Combining Scintigraphy (SPECT) Using a Specific Transporter and Magnetic Resonance Imaging (MRI) (DatScan)

Lewy Body Dementia

France
University Hospital, Geneva

Completed

Prospective Evaluation of Laparoendoscopic Single Site Versus Laparoscopic Cholecystectomy

Gallbladder Disease

Switzerland
AstraZeneca

Completed

Safety, Tolerability, and Pharmacokinetics of AZD7268 After Single Ascending Oral Doses in Healthy Subjects

Healthy Volunteer

United States
AstraZeneca

Completed

AZD8529 Single Ascending Dose Study in Healthy Japanese Subjects (JSAD)

Healthy

United Kingdom
University of California, Los Angeles

Completed

Alcohol Use Reduction in Methadone Individuals With Hepatitis C Virus(HCV) (NIAAA)

Hepatitis C

United States
Pfizer

Completed

A Phase 1 Multiple-Dose Escalation and Single Dose (Tablet) Study of PF-04171327 in Healthy Volunteers

Healthy Volunteers

Belgium
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study to Determine the Impact of Multiple Doses of Rifampin on Single-dose Pharmacokinetics of HCV-796

Healthy
East Tallinn Central Hospital

Unknown

MOR and COMT SNP Polymorphism and Pain

Pain Relief

Estonia
Medlogics Device Corporation
Stanford University; Baim Institute for Clinical Research

Unknown

Cobra II Study: Use of the Cobra™ Cobalt Super Alloy Coronary Stent System in the Treatment of Coronary Artery Disease

Coronary Artery Disease

Israel, United Kingdom, Netherlands, Germany
Wyeth is now a wholly owned subsidiary of Pfizer
Solvay Pharmaceuticals

Terminated

Study Evaluating the Safety and Tolerability of Single Ascending Dose (SAD) SLV-351 in Healthy Subjects

Healthy

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