Search clinical trials for: Working mechanisms

Total 96825 results

Abbott

Withdrawn

A Study Exploring an Induction-Maintenance Kaletra-Based Therapy Versus a Sustiva-Based Regimen in Previously Non-Treated, HIV-1/HCV Co-Infected Subjects

HIV Infection | Hepatitis C
Abbott

Completed

Study of Lopinavir, Ritonavir, Tenofovir and Emtricitabine in HIV-Infected Antiretroviral Naïve Subjects

HIV Infections

Spain, United Kingdom, United States, France, Australia, Germany, Singapore
Abbott

Completed

Effectiveness of ABT-378/Ritonavir Plus Lamivudine Plus Efavirenz Plus Tenofovir DF in HIV-Infected Patients

HIV Infections

United States
Gachon University Gil Medical Center

Completed

Safety and Effects of Ramipril Combined With Candesartan

Hypertension
Abarbanel Mental Health Center

Completed

Tolerability and Efficacy of High Dose Escitalopram for the Treatment of Obsessive-Compulsive Disorder (OCD)

Obsessive-Compulsive Disorder

Israel
Eli Lilly and Company
Boehringer Ingelheim

Completed

Safety and Effectiveness Study of Duloxetine HCl in Women of Different Backgrounds With Stress Urinary Incontinence Who May Also Have Other Various Medical Conditions.

Stress Urinary Incontinence

United States
Pfizer
PPD

Completed

A First In Human Study Of PF-00184562 In Healthy Volunteers

Schizophrenia

United States
Eli Lilly and Company

Completed

Duloxetine in the Treatment of Melancholic Depression

Depressive Disorder, Major

Australia, Canada
Eli Lilly and Company

Completed

Switching to Duloxetine From Other Antidepressants

Major Depressive Disorder

Spain, France, Ireland, United Kingdom
Pfizer

Completed

Assessment Of Duration Of Action, Safety & Toleration Of UK369,003 and Cialis In Patients With Erectile Dysfunction

Impotence
Eli Lilly and Company

Completed

Optimal Length of Treatment Continuation With Olanzapine After Remission of Manic or Mixed Episode

Bipolar Disorder

Spain
Eli Lilly and Company

Completed

Olanzapine in Patients With Borderline Personality Disorder

Borderline Personality Disorder

Germany, United States, Belgium, France, Norway, Portugal, Spain, Sweden, United Kingdom
Eli Lilly and Company

Completed

A Functional Outcomes Study With Atomoxetine-Hydrochloride and Placebo in Adults With Attention-Deficit/Hyperactivity Disorder

Attention Deficit Disorder With Hyperactivity

United States
Eli Lilly and Company

Completed

Efficacy and Safety of Olanzapine in Patients With Borderline Personality Disorder

Borderline Personality Disorder

United States, Argentina, Poland, Romania, Turkey
Eli Lilly and Company

Completed

The Study of Olanzapine Plus Fluoxetine in Combination for Treatment of Treatment Resistant Depression

Major Depressive Disorder

United States, Canada
Pfizer

Completed

Pregabalin Open-Label Extension Trial in Patients With Partial Seizures

Epilepsies, Partial | Epilepsy, Complex Partial

Spain, France, Canada, Germany, Italy, Lithuania, Austria, United Kingdom
Eli Lilly and Company

Completed

Gemcitabine in Combination With Cisplatin as Neoadjuvant NSCLC Chemotherapy

Carcinoma, Non-Small-Cell Lung

Russian Federation
Kamuzu University of Health Sciences

Completed

Intranasal Lorazepam Versus Intramuscular Paraldehyde in Paediatric Convulsions

Status Epilepticus | Convulsions

Malawi
Drug Commission of the German Medical Association
Madaus AG

Terminated

Cholesterol-Lowering Effects of Policosanol

Hypercholesterolemia | Combined Hyperlipidemia
Eli Lilly and Company

Completed

A Combination of Two Currently Approved Drugs to Enhance the Treatment of Schizophrenia

Schizophrenia

United States
Universiteit Antwerpen
Abbott

Completed

Selection of Antibiotic Resistance by Azithromycin and Clarithromycin in the Oral Flora

Healthy Volunteers

Belgium
Eli Lilly and Company

Completed

A Phase 2 Trial of ALIMTA (Pemetrexed) Plus Gemcitabine in Locally Advanced or Metastatic Transitional Cell Carcinoma of the Urothelium

Urologic Neoplasms

Finland, France, Germany
National Eye Institute (NEI)

Completed

Laser and Medical Treatment of Diabetic Macular Edema

Macular Degeneration

United States
Eli Lilly and Company

Completed

Olanzapine Versus Active Comparator in the Treatment of Depression in Patients With Schizophrenia

Depression | Schizophrenia | Schizoaffective Disorder

United States
Eli Lilly and Company

Completed

Subject Information and Consent Form F1J-US-HMCB Duloxetine Once-Daily Dosing Versus Placebo in Patients With Major Depression and Pain

Depression | Pain

United States
Eli Lilly and Company

Completed

A Phase 3 Trial of ALIMTA (LY231514, Pemetrexed) Plus GEMZAR Versus GEMZAR in Patients With Unresectable or Metastatic Cancer of the Pancreas.

Pancreatic Neoplasms | Metastases, Neoplasm

United States, France, United Kingdom, Germany, Taiwan, Spain, Belgium, Portugal, Peru, Austria, Italy, Sweden, Netherlands, Venezuela, Argentina, Australia, Colombia, Greece
Eli Lilly and Company

Completed

A Phase 2 Trial of Antisense Nucleotide to PKC-Alpha (LY900003, ISIS 3521) Plus Gemcitabine and Carboplatin in Patients With Advanced, Previously Untreated Non-Small Cell Lung Cancer.

Carcinoma, Non-Small-Cell Lung | Neoplasms, Lung | Pulmonary Neoplasms

United States
Eli Lilly and Company

Completed

A Phase 2 Trial of ALIMTA (Pemetrexed) in Locally Advanced or Metastatic Recurrent Transitional Cell Carcinoma of the Urothelium

Urologic Neoplasms | Metastases, Neoplasm

United States
Eli Lilly and Company

Completed

Olanzapine Versus An Active Comparator in the Treatment of Schizophrenia

Schizophrenia

United States, United Kingdom, Spain, Argentina, Mexico, Brazil, Peru, Puerto Rico, Germany, Austria, Ireland, Venezuela
Eli Lilly and Company

Completed

Study of Alimta and Epirubicin Administered in Patients With Locally Advanced or Metastatic Breast Cancer

Breast Cancer

Argentina, Belgium, Brazil, Mexico, Portugal
Eli Lilly and Company

Completed

Duloxetine Versus Placebo in the Prevention of Relapse of Major Depressive Disorder

Depressive Disorder

United States
Eli Lilly and Company

Completed

Comparing 3 Schedules of Alimta Plus Gemzar

Neoplasms | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms

United States
Eli Lilly and Company

Completed

A Phase II Study of a Combination of MTA (LY231514) and Gemcitabine in Patients With Metastatic Breast Cancer.

Breast Neoplasms

United States
Eli Lilly and Company

Completed

Open-Label Treatment With Duloxetine Hydrochloride Once-Daily Dosing for Evaluation of Stabilization Dose in Patients With Major Depression

Major Depressive Disorder

United States
Eli Lilly and Company

Completed

A Trial of ALIMTA (Pemetrexed) Plus Irinotecan in Patients Who Have Been Previously Treated For Metastatic Colorectal Cancer.

Colorectal Cancer

United States, Germany
Eli Lilly and Company

Completed

Olanzapine Versus Active Comparator in the Treatment of Bipolar I Disorder

Bipolar Disorder

United States
Eli Lilly and Company

Completed

A Phase II Study to Determine the Efficacy and Safety of Sivelestat in Subjects With Acute Lung Injury

Acute Lung Injury | Respiratory Distress Syndrome, Adult

United States, Belgium, Spain, Canada, Australia, New Zealand
Eli Lilly and Company

Completed

Pharmacokinetic Characterization of Intramuscular Olanzapine Depot

Schizophrenia | Schizoaffective Disorder

Australia, Belgium, Brazil, Croatia, Czech Republic, Mexico, Slovakia, Spain
Eli Lilly and Company

Completed

Dose Escalation, Double-Blind Treatment With Duloxetine Hydrochloride Once Daily Dosing for Evaluation of Safety in Major Depression

Major Depressive Disorder

United States
University of Milan

Completed

Contrast Nephropathy Prevention With N-Acetylcysteine in Acute Myocardial Infarction

Acute Myocardial Infarction | Contrast-Induced Nephropathy

Italy
National Cancer Institute (NCI)

Completed

A Phase I Trial of 5-Fluorouracil Given With 776C85 (GW776) and Low-Dose Leucovorin in Adult Patients With Solid Tumors

Neoplasms | Lymphoma

United States
Laval University
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Effect of Calcium/Vitamin D Supplementation on Body Weight and Fat Loss.

Obesity | Overweight

Canada
University of Toronto

Unknown

A Study of the Effect of Time on Topical Anesthetic Efficacy.

Pain

Canada
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Treatment of T-Large Granular Lymphocyte (T-LGL) Lymphoproliferative Disorders With Cyclosporine

Anemia | Thrombocytopenia | Neutropenia | Leukemia, T-Cell | Lymphocytosis

United States
Pfizer

Completed

Determine Long-Term Safety and Tolerability of Pregabalin in Patients With Anxiety Disorders.

Anxiety Neuroses

Spain, Belgium, South Africa, Germany, United Kingdom, Poland, Austria, Estonia, France, Israel, Italy, Latvia, Netherlands, Ukraine
Advanced-J
Japan Heart Foundation

Unknown

A Study on Ca Blocker Versus AII Antagonists in Hypertension With Type 2 Diabetes

Hypertension | Diabetes Mellitus, Type 2

Japan
National Institute of Neurological Disorders and...

Completed

Dextromethorphan for the Treatment of Parkinson's Disease and Similar Conditions of the Nervous System

Parkinson's Disease | Neurodegenerative Disease

United States
National Institute of Neurological Disorders and...

Completed

Safety Study of Idebenone to Treat Friedreich's Ataxia

Friedreich Ataxia

United States
Chiron Corporation

Completed

Tezacitabine With or Without 5-Fluorouracil (5-FU) for Advanced Esophageal Cancer or Gastric Cancer

Adenocarcinoma | Stomach Neoplasms | Esophageal Neoplasms

United States
Chiron Corporation

Terminated

Tezacitabine and Oxaliplatin for the Treatment of Patients With Metastatic Colorectal Cancer

Colorectal Neoplasms

United States

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