Search clinical trials for: pharmacokinetics

Total 10329 results

University of Turku

Completed

Bioavailability of Dexmedetomidine After Intranasal Administration (INDEX)

Sedation

Finland
Pfizer
Medivation, Inc.

Completed

A Study In Healthy Volunteers To Estimate The Pharmacokinetics Of Four Modified-Release Formulations Of Dimebon (Latrepirdine)

Huntington Disease | Alzheimer's Disease

United States
Pfizer

Completed

An Investigation Of The Effects Of Food On The Absorption Of A Varenicline Controlled Release Formulation

Smoking Cessation | Pharmacokinetics | Bioavailability

United States
Pfizer

Completed

A Study To Investigate The Safety, Toleration And Pharmacokinetics Of Single Oral Doses Of PF-03864086 In Healthy Male Subjects

Pain

Belgium
Pfizer

Completed

A Multiple Dose Study To Determine Safety, Tolerability And Pharmacokinetics Of PF-04455242 In Healthy Adult Subjects

Healthy

Singapore
Mutual Pharmaceutical Company, Inc.

Completed

A Pharmacokinetic Study of Colchicine With an Oral Contraceptive

Pharmacokinetics

United States
Fred Hutchinson Cancer Center
National Center for Complementary and Integrative Health (NCCIH)

Completed

Effects of Garlic Supplements on Drug Metabolism

Healthy

United States
Pfizer
Medivation, Inc.

Completed

A Phase 1, Non-Randomized, Open-Label, Single-Dose Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF 01913539] In Subjects With Severely-Impaired And Normal Renal Function

Alzheimer's Disease | Huntington's Disease

United States
Boryung Pharmaceutical Co., Ltd

Completed

A Study to Assess Food Effect on the Pharmacokinetics of Fimasartan in Healthy Male Volunteers

Healthy
Pfizer

Terminated

Multiple Dose Study in Healthy Volunteers to Assess Safety, Pharmacokinetics and Pharmacodynamics of PF 03882845

Healthy Volunteers

United States
AstraZeneca

Terminated

Study to Evaluate Efficacy, Safety, Tolerability and Pharmacokinetics of AZD1386 in Patients With Peripheral Neuropathic Pain (AVANT)

Pain | Neuropathic Pain

France, United Kingdom, Canada, Denmark
Norgine

Completed

Effect of Chronic Viral Hepatitis on the Pharmacokinetics of NRL972.

Hepatitis, Viral, Human

Bulgaria, Romania
AstraZeneca

Completed

Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD3043

Healthy

Sweden
University of North Carolina, Chapel Hill

Completed

Mechanisms Underlying Drug-Diet Interactions

Pharmacokinetics

United States
Pfizer

Completed

To Investigate The Safety, Toleration And Pharmacokinetics Of Single Oral Doses Of PF-04531083 In Healthy Male Subjects

Pain

Belgium
Tufts University

Completed

Pharmacokinetics of Carnosine

Oxidative Stress

United States
Bristol-Myers Squibb

Completed

The Effect of Omeprazole on the Pharmacokinetics of Dasatinib in Healthy Subjects

Healthy

United States
Sanofi

Completed

Pharmacokinetics and Safety Study With Alfuzosin in Children and Adolescents With Elevated Detrusor Leak Point Pressure of Neuropathic Etiology (ALFACHIP)

Urinary Bladder Neurogenic

Serbia, United States
National Center for Complementary and Integrative...

Terminated

A Study of the Pharmacokinetics of Black Cohosh

Hot Flashes

United States
AstraZeneca

Completed

Efficacy, Safety, & Pharmacokinetics of Candesartan Cilexetil in Hypertensive Paediatric Subjects 6 to < 17 Years of Age

Hypertension

United States, Hungary, Slovakia, Belgium
Queen's University

Completed

Plasma Gabapentin Concentration During and Following Cardiac Bypass

Cardiopulmonary Bypass

Canada
Pfizer

Completed

Study Of Single Ascending And Multiple Doses Of PF-04447943 In Japanese Subjects.

Healthy

United States
Astellas Pharma Inc

Completed

Relative Bioavailability Study of Solifenacin Succinate Liquid Suspension (Fed and Fasting) Versus VESIcare Tablet (Fasting) in Healthy Volunteers

Healthy Volunteers | Pharmacokinetics of Solifenacin Succinate | Bioavailability of Solifenacin Succinate

United States
University of Cologne
University Hospital, Bonn; ZKS Köln

Completed

An Explorative Study on the Pharmacokinetics and Pharmacodynamics of Sunitinib in Healthy Volunteers

Blood Pressure
VIVUS LLC

Completed

Evaluate the Effect of VI-0521 on the Pharmacokinetics of Oral Contraceptive in Healthy Female Subjects

Healthy

United States
VIVUS LLC

Completed

To Evaluate The Effect Of Ketoconazole, Ritonavir and Erythromycin on the Safety and Pharmacokinetics of Avanafil

Erectile Dysfunction

United States
VIVUS LLC
Covance; Sentrx

Completed

A Study to Evaluate the Pharmacokinetics of VI-0521 in Subjects With Hepatic Impairment

Hepatic Impairment

United States
VIVUS LLC

Completed

A Study to Evaluate the Pharmacokinetics of VI-0521 Subjects With Renal Impairment

Renal Impairment

United States
Mutual Pharmaceutical Company, Inc.

Completed

Pharmacokinetic and Exploratory Electrocardiogram (ECG) Study

Pharmacokinetics

United States
Pfizer

Completed

Multiple Oral Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PF-04878691

Hepatitis C Virus

United States
Guangzhou First People's Hospital

Unknown

The Pharmacokinetics of Nifedipine Controlled Release Tablets in Hypertensive Patients on Hemodialysis (PICASSO)

Hypertension on Chronic Maintenance Hemodialysis

China
AstraZeneca

Completed

Study to Assess Drug Concentrations in Plasma of Different Extended-release Formulations of AZD1305

Healthy

United Kingdom
Mutual Pharmaceutical Company, Inc.

Completed

Pharmacokinetic Study of an Acute Gout Regimen

Pharmacokinetics

United States
AstraZeneca

Terminated

Open-Label Absorption, Distribution, Metabolism, Excretion (ADME) and Pharmacokinetics (PK) Following a Single Oral Dose of AZD1236 in Healthy Male Subjects

Healthy

United Kingdom
Mutual Pharmaceutical Company, Inc.

Completed

Pharmacokinetic Study With Colchicine in Healthy Volunteers

Pharmacokinetics

United States
Novartis Pharmaceuticals

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of APL180

Coronary Heart Disease

Germany, United States, Denmark, Israel, Netherlands
Novartis

Completed

Study to Investigate the Effect of Deferasirox on the Pharmacokinetics of Midazolam

Healthy
Novartis Pharmaceuticals

Terminated

The Effects of Patupilone on the Pharmacokinetics and Pharmacodynamics of Warfarin in Patients With Advanced Malignancies

Advanced Malignancies

United States
Chong Kun Dang Pharmaceutical

Completed

Study to Evaluate the Pharmacokinetic Characteristics of CKD-4101 (Mycophenolate Mofetil) Tablet

Healthy

Korea, Republic of
Novartis
Bayer

Completed

Study of the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Effects of Vatalanib in Combination With Capecitabine in Patients With Advanced Cancer

Neoplasm Metastasis | Tumors

United States
Novartis Pharmaceuticals

Completed

Evaluate the Effects of Patupilone on the Pharmacokinetics and Pharmacodynamics of Warfarin in Patients With Advanced Malignancies

Advanced Malignancies

United States
Novartis

Completed

Effect of a Potent Inducer Rifampicin on the Pharmacokinetics of Deferasirox in Healthy Volunteers

Healthy
Pfizer
Medivation, Inc.

Completed

A Phase I Study To Estimate The Effect Of Ketoconazole And Omeprazole On The Pharmacokinetics Of Dimebon In Healthy Subjects Who Are Normal Or Poor CYP2D6 Metabolizers

Alzheimer's Disease | Huntington's Disease

United States
Boryung Pharmaceutical Co., Ltd

Completed

A Study to Evaluate the Effect of Fimasartan on Pharmacokinetics, and the Safety of Digoxin in Healthy Male Volunteers

Essential Hypertension
Mutual Pharmaceutical Company, Inc.

Completed

Bioequivalence Study of Fenofibric Acid Versus Tricor® (Fenofibrate)

Healthy

United States
AstraZeneca

Completed

To Study Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1656 in Japanese Type 2 Diabetes Mellitus (T2DM) Patients (JMAD)

Type 2 Diabetes

Japan
Dana-Farber Cancer Institute
Massachusetts General Hospital; Brigham and Women's Hospital

Completed

Using Positron Emission Tomography to Evaluate the Effects of Bevacizumab on Intra-tumoral Pharmacokinetics of 5-fluorouracil in Metastatic Colorectal Cancer

Neoplasm Metastasis | Colorectal Cancer

United States
Mutual Pharmaceutical Company, Inc.

Completed

Drug-Drug Interaction Study of Colchicine and Azithromycin

Pharmacokinetics
Mutual Pharmaceutical Company, Inc.

Completed

Drug - Drug Interaction Study Between Quinine Sulfate and Theophylline

Pharmacokinetics

United States
AstraZeneca

Completed

A Study to Determine the Effect of Food on the Pharmacokinetics of Oral AZD8931 Tablets

Healthy

United Kingdom

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