- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00721708
Pharmacokinetics of Carnosine
December 14, 2009 updated by: Tufts University
The absorption kinetics of dietary carnosine (β-alanyl-L-histidine) will be determined in the healthy adults.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Study Type
Interventional
Enrollment (Actual)
4
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Massachusetts
-
Boston, Massachusetts, United States, 02111
- Jean Mayer USDA-Human Nutrition Research Center on Aging at Tufts University
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
40 years to 70 years (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
Female
Description
Inclusion Criteria:
- Healthy adult
- normal hematological parameters, normal serum albumin, normal liver function, normal kidney function
Exclusion Criteria:
- History of smoking or alcoholism
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Interventional Model: Crossover Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: 1
Carnosine(450 mg)
|
one time dose of pure carnosine (450 mg)
|
Experimental: 2
Beef (150g)
|
one time dose, 150 g of beef
|
Experimental: 3
chicken (150g)
|
One time dose, 150g of chicken breast
|
Experimental: 4
Chicken broth (obtained from 150 g of chicken breast)
|
one time dose of chicken broth obtained from 150g of chicken breast
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Plasma histidine-dipeptide
Time Frame: 0, 30, 60, 100, 180, 240, & 300 min
|
0, 30, 60, 100, 180, 240, & 300 min
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
April 1, 2007
Primary Completion (Actual)
October 1, 2007
Study Completion (Actual)
July 1, 2008
Study Registration Dates
First Submitted
July 22, 2008
First Submitted That Met QC Criteria
July 23, 2008
First Posted (Estimate)
July 24, 2008
Study Record Updates
Last Update Posted (Estimate)
December 15, 2009
Last Update Submitted That Met QC Criteria
December 14, 2009
Last Verified
December 1, 2009
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- TMC/TUHS IRB 7737
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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