Search clinical trials for: ALS-008176

Total 255611 results

Zimmer Biomet

Completed

Prospective Post-Market Data Collection on Patients With Knee OA and Treated With nSTRIDE APS (PROGRESS III)

Osteoarthritis, Knee

United Kingdom
Alnylam Pharmaceuticals

Completed

Dose Escalation Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Intravenous ALN-VSP02 In Patients With Advanced Solid Tumors With Liver Involvement

Solid Tumors

United States, Spain
Aqualung Therapeutics Corp.

Not yet recruiting

Study of Safety and Efficacy of ALT-100mAb in Participants With Moderate/Severe ARDS

Acute Respiratory Distress Syndrome (ARDS)
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co...

Completed

Pharmacokinetics and Safety of ALA in Acne Vulgaris

Acne Vulgaris

China
Alnylam Pharmaceuticals

Terminated

A Study to Evaluate ALN-XDH in Healthy Subjects and Patients With Gout

Gout

United Kingdom
Alnylam Pharmaceuticals

Completed

Multi-center, Open Label, Extension Study of ALN-VSP02 in Cancer Patients Who Have Responded to ALN-VSP02 Treatment

Solid Tumors

United States, Spain
Institut d'Investigació Biomèdica de Bellvitge

Recruiting

Infectious Diseases Experts as Part of the Antibiotic Stewardship Team in Primary Care (IDASP)

Infectious Disease

Spain
Regeneron Pharmaceuticals

Not yet recruiting

A Trial to Learn if Receiving ALN-PNP siRNA is Safe and Well Tolerated, and How it Works in Adult Participants With Nonalcoholic Fatty Liver Disease (NAFLD) and a Genetic Risk Factor

Nonalcoholic Steatohepatitis (NASH) | Nonalcoholic Fatty Liver Disease (NAFLD) | Genetic Risk Factor
Alnylam Pharmaceuticals

Terminated

A Study of ALN-HSD in Healthy Adult Subjects and Adult Patients With Nonalcoholic Steatohepatitis (NASH)

Nonalcoholic Steatohepatitis | NASH

United States, Bulgaria, United Kingdom, Belgium, Turkey
Alnylam Pharmaceuticals

Terminated

A Study of Cemdisiran in Adults With Immunoglobulin A Nephropathy (IgAN)

IgA Nephropathy (IgAN) | Berger Disease | Glomerulonephritis, IgA

Canada, Malaysia, France, Sweden, United Kingdom, Philippines, Singapore, Spain, Taiwan
Zimmer Biomet

Completed

APSS-33-00: A Multicenter, Pilot Study of Autologous Protein Solution (APS) in Knee Osteoarthritis (OA) (PROGRESS II)

Osteoarthritis, Knee

Italy, Austria, Belgium, Norway
Synvista Therapeutics, Inc

Completed

The SAPPHIRE Study (Systolic And Pulse Pressure Hemodynamic Improvement By Restoring Elasticity)

Hypertension
Regeneron Pharmaceuticals

Recruiting

A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Non-Alcoholic Steatohepatitis (NASH) in Adult Participants at Increased Genetic Risk for This Condition (NASHGEN-2)

Non-alcoholic Steatohepatitis (NASH) | Metabolic Dysfunction Associated Steatohepatitis (MASH)

United States, Korea, Republic of, Puerto Rico, Japan
Jan Frystyk

Recruiting

Cross-sectional Study of 1200 Recreational Athletes With Former or Current Use of Androgenic Anabolic Steroids (FIDODK/BIC)

Heart Failure | Cardiovascular Morbidity | Androgen Deficiency

Denmark
Fox Chase Cancer Center

Recruiting

Phase I Study in Advanced Malignancies With 5-ALA

Solid Tumor

United States
Alnylam Pharmaceuticals

Terminated

A Study of ALN-AAT02 in Healthy Participants and Participants With ZZ Type Alpha-1 Antitrypsin Deficiency Liver Disease

ZZ Type Alpha-1 Antitrypsin Deficiency Liver Disease

United Kingdom
Shanghai Changzheng Hospital

Unknown

ALK Inhibitor in Metastatic Colorectal Cancer With ALK Mutation.

Colorectal Cancer

China
Henry Friedman

Completed

Pilot Study of Bone Marrow/Stem Cells in Grade IV Malignant Glioma

Grade IV Malignant Glioma

United States
Synvista Therapeutics, Inc

Completed

The SILVER Study: Systolic Hypertension Interaction With Left Ventricular Remodeling

Hypertension | Hypertrophy, Left Ventricular
Yale University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Juvenile...

Completed

Anti-CD3 mAb Treatment of Recent Onset Type 1 Diabetes

Type 1 Diabetes Mellitus

United States
Aligos Therapeutics

Recruiting

ALG-055009 in Non-cirrhotic Adults With MASH (HERALD) (HERALD)

Nonalcoholic Steatohepatitis | NASH | MASH | Metabolic Dysfunction-Associated Steatohepatitis

United States
First Affiliated Hospital Xi'an Jiaotong University

Recruiting

Registry Study for Optimal Management of Liver Failure in the Chinese Population (RESOLVE-C)

Liver Failure

China
Biogen
Alkermes, Inc.

Completed

A Study of ALKS 8700 in Adults With Relapsing Remitting Multiple Sclerosis (MS) EVOLVE-MS-1

Multiple Sclerosis

United States, Bulgaria, Poland, Belgium, Canada, Germany, Russian Federation, Serbia, Spain, Ukraine
Alume Biosciences, Inc.

Completed

A Study of ALM-488 to Highlight Nerves in Patients Undergoing Head & Neck Surgery

Head and Neck Neoplasms | Surgery | Thyroid Neoplasms | Nerve Injury | Parotid Neoplasm | Imaging

United States
Alnylam Pharmaceuticals

Completed

The Study of an Investigational Drug, Revusiran (ALN-TTRSC), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Whose Disease Has Continued to Worsen Following Liver Transplant

ATTR Amyloidosis | Transthyretin (TTR)-Mediated Amyloidosis | Familial Amyloidotic Polyneuropathy (FAP) | Familial Amyloid Neuropathies

France, Germany, Portugal, United Kingdom, Sweden, Spain
Alkermes, Inc.

Completed

A Long-Term Safety Study of ALKS 5461

Major Depressive Disorder

United States, Canada, Germany, Puerto Rico, Bulgaria, Australia, Poland, Hungary
Regeneron Pharmaceuticals
Sanofi

Recruiting

Neoadjuvant Cemiplimab for the Treatment of Resectable NSCLC, HCC, and HNSCC in Adult Patients

Hepatocellular Carcinoma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma

United States
Veloce BioPharma LLC

Completed

ALC-919 For The Treatment Of Common Warts

Verruca Vulgaris

United States
University of Toronto
Iovate Health Sciences International Inc

Recruiting

Effect of Green Coffee Extract Combined With Alpha-Lipoic Acid on Blood Glucose Homeostasis in Healthy Adults (GCE)

Nutrition, Healthy

Canada
Tata Memorial Hospital

Completed

Fluorescence and Glioma Heterogeneity (ALAglioma)

Malignant Gliomas

India
University of California, San Diego

Recruiting

Neoadjuvant Immunoradiotherapy With Evorpacept and Pembrolizumab in HPVOPC (Human Papilloma Virus Oropharynx Cancer)

Oropharynx Cancer

United States
Regeneron Pharmaceuticals

Completed

Pozelimab and Cemdisiran Combination Therapy in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria Who Switch From Eculizumab Therapy

Paroxysmal Nocturnal Hemoglobinuria

United Kingdom
University of Minnesota

Completed

Proof of Principle Study of Pulse Dosing of IL-15 to Deplete the Reservoir in HIV Infected People (ALT-803)

HIV | Stable ART

United States
Alkermes, Inc.

Completed

A Study of ALKS 5461 for the Treatment of Major Depressive Disorder (MDD) - FORWARD-5 Study

Major Depressive Disorder

United States, Canada, Germany, Puerto Rico
Alkermes, Inc.

Completed

A Drug-drug Interaction Study of ALKS 5461 in Healthy Volunteers

Healthy Volunteers

United States
Dartmouth-Hitchcock Medical Center

Withdrawn

A Proof of Principle Study of Aminolevulinic Acid (ALA) - Induced Fluorescence Detection in Resectable Non-Small Cell Lung Cancer

Lung Cancer in Normal and Malignant Tumors

United States
North-West University, South Africa
Medical Research Council, South Africa; National Research Foundation of South... and other collaborators

Completed

Effect of African Leafy Vegetables on Nutritional Status of South African School Children. (ALV)

Malnutrition | Vitamin A Status | Iron Status | Zinc Status

South Africa
Alnylam Pharmaceuticals

Recruiting

A Phase 1/2 Study to Evaluate ALN-KHK in Overweight to Obese Healthy Volunteers and Obese Patients With T2DM

Type 2 Diabetes Mellitus (T2DM)

Canada, United States
Alnylam Pharmaceuticals

Completed

Patisiran in Patients With Hereditary Transthyretin-mediated Amyloidosis (hATTR Amyloidosis) Disease Progression Post-Liver Transplant

Amyloidosis, Familial | Transthyretin Amyloidosis

France, Germany, Italy, Portugal, Spain, Sweden, United Kingdom
Alteogen, Inc.

Completed

Clinical Study of ALT-L9 to Determine Safety, Efficacy and Pharmacokinetics in Neovascular AMD

Neovascular Age-related Macular Degeneration

Korea, Republic of
Regeneron Pharmaceuticals
Alnylam Pharmaceuticals

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Pozelimab in Combination With Cemdisiran in Healthy Adult Volunteers

Healthy

Belgium
Mario Negri Institute for Pharmacological Research
Alnylam Pharmaceuticals

Withdrawn

Eculizumab to Cemdisiran Switch in aHUS (DANCE)

Atypical Hemolytic Uremic Syndrome

Italy
Alkermes, Inc.

Completed

A Study of ALKS 5461 for the Treatment of Major Depressive Disorder (MDD) - the FORWARD-3 Study

Major Depressive Disorder

United States, Bulgaria
Alkermes, Inc.

Completed

A Study to Evaluate ALKS 5461 in Subjects With Major Depressive Disorder (MDD)

Major Depressive Disorder

United States
Argos Therapeutics

Terminated

A Rollover Protocol for Subjects Previously Treated With AGS-003

Renal Cell Carcinoma

United States
Regeneron Pharmaceuticals

Recruiting

A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Non-Alcoholic Fatty Liver Disease (NAFLD)

Healthy Volunteers | Non-alcoholic Fatty Liver Disease (NAFLD)

United States
Regeneron Pharmaceuticals

Recruiting

A Study to Examine the Long-term Safety, Tolerability, and Effectiveness of Pozelimab and Cemdisiran Combination Therapy in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (ACCESS-EXT)

Paroxysmal Nocturnal Hemoglobinuria

Taiwan, Korea, Republic of, Turkey, Spain, Thailand, Singapore, Japan, Canada, Malaysia, Poland, Italy
Alzinova AB
CRST Oy

Recruiting

A Study on the Safety, Tolerability and Immunogenicity of ALZ-101 in Participants With Early Alzheimer's Disease

Alzheimer Disease | Dementia Alzheimers | Dementia, Mild

Finland
Altimmune, Inc.

Completed

Extension of ALT-801 in Diabetic and Non-Diabetic Overweight and Obese Subjects With (NAFLD)

Non-Alcoholic Fatty Liver Disease

United States
Altimmune, Inc.

Completed

ALT-801 in Diabetic and Non-Diabetic Overweight and Obese Subjects With Non-alcoholic Fatty Liver Disease (NAFLD)

Non-Alcoholic Fatty Liver Disease

United States

Search clinical trials for: ALS-008176

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