Clinical Trials Sponsored by Biocard

Total 656 results

Biocad

Completed

The Study of PK, PD, Safety of Multiple Intravenous Injections of BCD-066 and Aranesp in Healthy Volunteers

Healthy

Russian Federation
Biocad

Completed

Study of Pharmacokinetics, Pharmacodynamics, Safety of BCD-131 Compared to Mircera and Aranesp in Healthy Volunteers

Reticulocyte Count
Biocad

Completed

Phase I Study of BCD-145 (Anti-CTLA-4) in Patients With Unresectable/Metastatic Melanoma

Melanoma

Russian Federation
Biocad

Completed

Clinical Trial to Evaluate Pharmacokinetics, Pharmacodynamics and Safety of Leucostim® Compared to Neupogen®

Leucocytosis
Biocad

Completed

A Safety and Efficacy Study of BCD-022 With Paclitaxel Compared to Herceptin With Paclitaxel in HER2+ Metastatic Breast Cancer Patients

Human Epithelial Receptor (HER)-2 Positive Breast Cancer

Ukraine, Russian Federation, Belarus, India
Biocad

Completed

An Open-label Randomized Multicenter Phase III Clinical Study Comparing Safety and Efficacy of Algeron (Cepeginterferon Alfa-2b) and and PegIntron (Peginterferon Alfa-2b) in Combination With Ribavirin as Combined Treatment of Chronic Hepatitis C in Human Immunodeficiency Virus-1 Infected Patients

Hepatitis | Hepatitis C | Hepatitis C/ Human Immunodeficiency Virus Coinfection

Russian Federation
Biocad

Completed

Open Label Study of Tolerability, Pharmacokinetics and Pharmacodynamics of BCD-054 (Pegylated Interferon Beta-1a), IM and SC, Compared to Rebif® and Avonex® in Healthy Volunteers

Healthy

Russian Federation
Biocad

Completed

Dose-finding Study of Empegfilgrastim for Neutropenia Prophylaxis in Patients With Breast Cancer

Chemotherapy-induced Neutropenia

Russian Federation
Biocad

Completed

Study of the Efficacy and Safety of Empegfilgrastim for Neutropenia Prophylaxis in Breast Cancer Patients

Chemotherapy-induced Neutropenia

Russian Federation
Biocad

Completed

Pharmacokinetics and Pharmacodynamics Study of BCD-033 Compared to Rebif® in Healthy Volunteers

Healthy

Russian Federation
Biocad

Completed

Algeron (Cepeginterferon Alfa-2b) Compared With PegIntron (Peginterferon Alfa-2b) for Treatment of Chronic Hepatitis C

Hepatitis | Hepatitis C

Russian Federation
Biocad

Recruiting

A Study of the Efficacy and Safety of Monotherapy With BCD-264 and Darzalex in Subjects With Relapsed and Refractory Multiple Myeloma (DARVIVA)

Multiple Myeloma

Russian Federation
Biocad

Recruiting

Study of the Safety, Pharmacodynamics and Efficacy of ANB-002 in Patients With Hemophilia B (SAFRAN)

Hemophilia B

Russian Federation
Biocad

Recruiting

A Study of Neoadjuvant Therapy With BCD-217 (Nurulimab + Prolgolimab) in Patients With Resectable Stage III Skin Melanoma (NEO-MIMAJOR)

Melanoma (Skin) | Melanoma Stage III

Russian Federation, Belarus
Biocad

Recruiting

Efficacy and Safety of Divozilimab in Patients With Neuromyelitis Optica Spectrum Disorders (AQUARELLE) (AQUARELLE)

Neuromyelitis Optica Spectrum Disorders

Russian Federation
Biocad

Recruiting

An International, Multicenter, Randomized, Double-Blind, Double-Masked Study of the Efficacy and Safety of BCD-132 (JSC BIOCAD, Russia) Using an Active Reference Drug (Teriflunomide) for the Treatment of Patients With Multiple Sclerosis (MIRANTIBUS)

Multiple Sclerosis

Russian Federation
Biocad

Recruiting

Efficacy and Safety of BCD-100 (Anti-PD-1) in Combination With Platinum-Based Chemotherapy as First Line Treatment in Patients With Advanced Non-Squamous NSCLC (DOMAJOR)

Non-Squamous Non-Small Cell Neoplasm of Lung

Czechia, Romania, Georgia, Hungary, Russian Federation, Slovakia
Biocad

Completed

Study of the Pharmacodynamics, Pharmacokinetics, Safety, and Immunogenicity of Single Escalating Doses of BCD-180 in Healthy Volunteers

Healthy

Russian Federation
Biocad

Active, not recruiting

Study of the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of BCD-180 in Patients With Axial Spondyloarthritis (ELEFTA)

Axial Spondyloarthritis

Russian Federation
Biocad

Active, not recruiting

Clinical Study of Efficacy and Safety of BCD-085 (Monoclonal Anti-IL-17 Antibody) in Psoriatic Arthritis (PATERA)

Psoriatic Arthritis

Russian Federation, Belarus
Biocad

Completed

Dose Escalation Study of the Pharmacodynamics, Pharmacokinetics, Safety, and Immunogenicity of BCD-132 in Patients With Relapsing-Remitting Multiple Sclerosis

Multiple Sclerosis

Russian Federation
Biocad

Completed

Comparative Clinical Trial to Evaluate Efficacy, Safety and Tolerance of BCD-054 and Avonex® for Treatment of Patients With Remitting-relapsing Multiple Sclerosis

Multiple Sclerosis, Relapsing-Remitting

Russian Federation
Biocad

Completed

Comparative Study of the Efficacy and Safety of BCD-131 and Mircera in Treatment of Anemia in CKD Patients on Dialysis

Anemia

Russian Federation, Belarus
Biocad

Completed

Comparative Clinical Trial of Efficacy and Safety of BCD-055 and Remicade® in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis

Rheumatoid Arthritis

India, Russian Federation, Belarus
Biocad

Completed

An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic Hepatitis C

Hepatitis | Hepatitis C

Belarus, Russian Federation, India, Thailand
Biocad

Unknown

A Study of BCD-135 in Patients With Advanced Solid Tumors

Melanoma | Renal Cell Carcinoma | NSCLC | Bladder Cancer

Russian Federation
Biocad

Completed

Comparative Clinical Trial to Evaluate Efficacy and Safety of BCD-055 and Remicade® in Patients With Ankylosing Spondylitis

Ankylosing Spondylitis

Russian Federation
Biocad

Completed

First-in-human Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Various Doses of BCD-121 in Healthy Subjects

Healthy
Biocad

Completed

Comparative Evaluation of Pharmacokinetics and Safety of BCD-055 and Remicade in Patients With Ankylosing Spondylitis

Ankylosing Spondylitis

Russian Federation, Belarus
Biocad

Withdrawn

Safety and Efficacy Study of BCD-021 Compared to Lucentis® in Patients With Neovascular Wet Age-related Macular Degeneration (GALATIR)

Wet Age-related Macular Degeneration

Brazil, Russian Federation
Nobel Biocare

Completed

The TREFOIL Concept 5 Year Clinical Investigation

Edentulous or Failing Dentition Mandible

Italy, United States, Australia, Chile, Spain
Nobel Biocare

Completed

A 5-year Clinical Evaluation Study on NobelReplace Conical Connection Implants

Healthy | Implant
Nobel Biocare

Completed

A 1-year Clinical Investigation on the On1 Concept (T-190)

Implant

Belgium, Italy, Lithuania, Netherlands
Nobel Biocare

Unknown

A 1-year Clinical Investigation on the the CREOS™ XENOGAIN Bone Graft SUBSTITUTE

Horizontal Bone Augmentation

Germany, Italy, Serbia
Nobel Biocare

Terminated

NobelProceraTM Bridge Shaded Zirconia

Posterior Bridge Restoration

Germany
Nobel Biocare

Completed

Immediate Function of NobelSpeedy Shorty and Brånemark System® Mk III Shorty Implants in Daily Use

Partial Edentulism | Complete Edentulism
Nobel Biocare

Recruiting

A Clinical Study on Implants With TiUltra Technology and Associated Prosthetic Components

Marginal Bone Level Change

Denmark
Nobel Biocare

Terminated

Nobel Procera Crown Shaded Zirconia and NobelProceraTM Full Contour Crown IPS e.Max CAD

Partial Edentulism

Germany
Nobel Biocare

Terminated

A 5 Year Clinical Investigation on Creos Xenoprotect (CXP)

Implant

Germany
Nobel Biocare

Completed

T-116_Procera-Bridge Zirconia - A Clinical Study

Partial Edentulism
Nobel Biocare

Completed

Randomized, Open Investigation Evaluating the Efficacy of Nobel Biocare SFB and CFB Implants

Partial Edentulism | Complete Edentulism
Nobel Biocare

Unknown

Extra Short Implants Brånemark System® RP Ø4.5x4.5 mm Implants

Healthy Volunteers With Severely Resorbed Jaws in Need of an Implant Supported Restoration

Germany
Nobel Biocare

Completed

Study Assessing the Safety and Effectiveness of the Nobel Biocare N1 Concept System. (Evolution)

Dental Implant

Hungary, Italy, Netherlands
Nobel Biocare

Completed

A 5 Year Clinical Study on NobelActive 3 mm Implants (NA 3 MM)

Single Tooth Implant
Nobel Biocare

Completed

A Study of Dental Implants Coated With Bone Morphogenetic Protein

Alveolar Ridge Abnormality

United States
Nobel Biocare

Terminated

All-On-4® Treatment Concept

Edentulous

Germany
Malo Clinic
Nobel Biocare

Active, not recruiting

Full Arch Rehabilitations Through the Contemporary All-on-4 Concept (AO4ContProt)

Edentulous Jaw

Portugal
Max Biocare Pty. Ltd.

Completed

Tregocel® as a Dietary Supplement in Mild Knee Osteoarthritis

Mild Knee Osteoarthritis

Poland
Xi'an Biocare Pharma Ltd.

Completed

A SAD/MAD Study to Evaluate the Safety, Tolerability, PK and PD of MT2004

Healthy

United States
BioCardia, Inc.

Not yet recruiting

AllogeneiC Expanded Human MSC Therapy in Patients Recovering From COVID-19 Acute Respiratory Distress Trial (ACE_CARD)

ARDS, Human

3

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