Clinical Trials Sponsored by Circadian Therapeutics Ltd

Total 474 results

PsiOxus Therapeutics Ltd

Completed

Phase I / Dose Expansion Study of Enadenotucirev in Ovarian Cancer Patients (OCTAVE)

Recurrent Platinum Resistant Ovarian Cancer

United Kingdom, Spain
PsiOxus Therapeutics Ltd

Completed

Mechanism of Action Trial of ColoAd1 (MOA)

Resectable Colon Cancer | Resectable Non-small Cell Lung Cancer | Resectable Bladder Cancer | Resectable Renal Cell Carcinoma

Spain
Vensica Therapeutics Ltd.

Completed

Vibe First In Human Study for the Assessment of Safety and Initial Performance of the Vibe Delivery System in Subjects With Idiopathic Overactive Bladder

Overactive Bladder

Czechia, Portugal
Celleron Therapeutics Ltd.

Unknown

A Trial of CXD101 in Combination With Nivolumab in Patients With Metastatic Microsatellite-Stable Colorectal Cancer (CAROSELL)

Colorectal Neoplasms Malignant

United Kingdom
SpotOn Therapeutics Ltd.

Suspended

Spoton Trial Evaluating the Efficacy on BAlance Disorder sYmptoms (STEADY) (STEADY)

Balance Disorders

Israel
Nerre Therapeutics Ltd.

Completed

A Pharmacokinetic Study of the Effect of Itraconazole Exposure to Orvepitant in Healthy Volunteers

Pharmacokinetic Study in Healthy Male Volunteers

United Kingdom
PhytoTech Therapeutics, Ltd.

Completed

A Study to Evaluate the Safety, Tolerability and Efficacy of Oral Administration of PTL101 (Cannabidiol) as an Adjunctive Treatment for Pediatric Intractable Epilepsy

Epilepsy Intractable

Israel
Bioceltech Therapeutics, Ltd.

Unknown

CD19-CAR-T Cells in Patients With R/R B-ALL

B-cell Acute Lymphoblastic Leukemia

China
TauRx Therapeutics Ltd

Completed

Safety and Efficacy Study Evaluating TRx0237 in Subjects With Mild to Moderate Alzheimer's Disease

Alzheimer's Disease

Korea, Republic of, United States, Spain, United Kingdom, Taiwan, Poland, Malaysia, Singapore, Canada, Croatia, Italy, Australia, Germany, Romania, Russian Federation, Bulgaria
PhytoTech Therapeutics, Ltd.

Unknown

Evaluation of the Safety, Tolerability, and Efficacy of Orally Administered PTL201 in MS Patients With Spasticity-related Symptoms

Multiple Sclerosis

Israel
Immodulon Therapeutics Ltd

Completed

A Study of IMM-101 in Combination With Radiation Induced Tumour Necrosis in Colorectal Cancer

Metastatic Colorectal Cancer

United Kingdom
Revive Therapeutics, Ltd.

Completed

Bucillamine for the Treatment of Acute Gout Flare in Subjects With Moderate to Severe Gout

Gout

United States
Vaxil Therapeutics Ltd.

Completed

A Study to Assess the Safety and Efficacy of MUC1 Peptide Vaccine and hGM-CSF in Patients With MUC1-positive Tumor Malignancies

Multiple Myeloma

Israel
Biokine Therapeutics Ltd

Completed

Safety Study of a Chemokine Receptor (CXCR4) Antagonist in Multiple Myeloma Patients

Multiple Myeloma

Israel
Arana Therapeutics Ltd

Terminated

Dose Ranging Study of ART621 in Subjects Diagnosed With Rheumatoid Arthritis Taking Methotrexate

Rheumatoid Arthritis

United States, Australia, Poland, Argentina, Czech Republic, India, Malaysia, New Zealand
Minovia Therapeutics Ltd.

Recruiting

Collection of Blood and Skin Samples From Patients With Primary Mitochondrial Diseases and Healthy Volunteers

Primary Mitochondrial Diseases

Israel
Apollo Therapeutics Ltd

Not yet recruiting

A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors

Colorectal Cancer | Pancreatic Adenocarcinoma | Ovarian Cancer | Prostate Cancer | Gastric Adenocarcinoma | Cholangiocarcinoma | Triple Negative Breast Cancer | Endometrial Adenocarcinoma | Appendiceal Adenocarcinoma
Apollo Therapeutics Ltd

Not yet recruiting

A Study to Investigate APL-4098 Alone and/or in Combination With Azacitidine in R/R AML and High-Risk MDS

Myelodysplastic Syndrome With Excess Blasts | Acute Myeloid Leukemia, in Relapse | Acute Myeloid Leukemia Refractory | Myelodysplastic Syndrome Acute Myeloid Leukemia
Minovia Therapeutics Ltd.

Recruiting

Collection of Samples of Bone Marrow Aspiration From Patients With Myelodysplastic Syndrome

Myelodysplastic Syndromes

Israel
Minovia Therapeutics Ltd.

Recruiting

Evaluate the Safety and Therapeutic Effects of Transplantation of MNV-201 in Pediatric Patients With Pearson Syndrome

Mitochondrial Diseases | Pearson Syndrome

Israel
Iksuda Therapeutics Ltd.

Recruiting

IKS03 in Patients With Advanced B Cell Non-Hodgkin Lymphomas

Follicular Lymphoma | B-cell Lymphoma | Mantle Cell Lymphoma | Diffuse Large B Cell Lymphoma | B-cell Non-Hodgkin Lymphoma

Australia, Canada, United States
Prescient Therapeutics, Ltd.

Recruiting

Phase 1 Study of PTX-100 in Patients With Advanced Malignancies With PTCL Expansion Cohort

Advanced Cancer | PTCL

Australia
Immodulon Therapeutics Ltd

Completed

A Study of IMM-101 in Combination With Checkpoint Inhibitor Therapy in Advanced Melanoma

Melanoma

United Kingdom
Prescient Therapeutics, Ltd.

Completed

A Study of PTX-200 (Triciribine) Plus Cytarabine in Refractory or Relapsed Acute Leukemia

Acute Leukemia

United States
Enlivex Therapeutics Ltd.

Terminated

A Phase 2b Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study, Evaluating Efficacy and Safety of Allocetra-OTS in Patients With Severe or Critical COVID-19 With Associated Acute Respiratory Distress Syndrome (ARDS)

Covid19

Israel
Raziel Therapeutics Ltd.

Completed

An Open Label Study That Will Test Safety and Efficacy of RZL-012 Injection Into the Submental Fat in Chinese vs. Non-Chinese Subjects.

Submental Fat

United States
Raziel Therapeutics Ltd.

Completed

An Open-label Study That Will Test a Second Treatment Session of RZL-012.

Submental Fat

United States
TauRx Therapeutics Ltd

Available

TRx0237 for the Treatment of Early and Mild-Moderate Alzheimer's Disease

Alzheimer Disease
Revive Therapeutics, Ltd.

Terminated

Bucillamine in Treatment of Patients With COVID-19

Covid19

United States, Puerto Rico
Immodulon Therapeutics Ltd

Terminated

A Long Term Follow up Study for Patients Who Previously Took Part in the Phase I Study IMM-101-001

Malignant Melanoma

United Kingdom
TauRx Therapeutics Ltd

Completed

Safety and Efficacy of TRx0237 in Subjects With Alzheimer's Disease Followed by Open-Label Treatment

Alzheimer Disease

United States, Spain, Poland, Belgium, France, United Kingdom, Italy, Canada
NeuroSense Therapeutics Ltd.

Completed

A Multiple-Dose PK Study to Evaluate the Comparative Bioavailability of PrimeC Tablets to Ciprofloxacin Tablets Co-administered With Celecoxib Capsules, in Healthy Adult Subject

Pharmacokinetics

United States
NeuroSense Therapeutics Ltd.

Completed

A Pilot Study to Evaluate the PK Profile of PrimeC-ER Tablets in Healthy Adult Subjects

Pharmacokinetics

United States
NeuroSense Therapeutics Ltd.

Completed

Ciprofloxacin/Celecoxib Combination in Patients With ALS

ALS (Amyotrophic Lateral Sclerosis)

United States
Minovia Therapeutics Ltd.

Completed

A Study to Evaluate the Safety and Therapeutic Effects of Transplantation of MNV-BM-BLD in Pediatric Patients With Pearson Syndrome

Mitochondrial Diseases | Pearson Syndrome

Israel
NeuroSense Therapeutics Ltd.

Completed

Open Label Study to Evaluate Ciprofloxacin/Celecoxib Combination in Patients With ALS

Amyotrophic Lateral Sclerosis | ALS

Israel
SpotOn Therapeutics Ltd.

Suspended

Treatment of Balance Disorders in Parkinson's Patients Using SpotOn Balance Glasses

Parkinson Disease

Israel
Raziel Therapeutics Ltd.

Completed

Treatment of Women With Lipedema Involving Substantial Fat Above the Knee or of Women and Men With Nodular Dercum's Disease

Dercum Disease | Lipedema

United States
Immodulon Therapeutics Ltd

Terminated

Study of IMM 101 in Combination With Standard of Care in Patients With Metastatic or Unresectable Cancer (MODULATE)

Metastatic Cancer

France, United Kingdom
Nerre Therapeutics Ltd.

Withdrawn

A Study of the Efficacy and Safety of Orvepitant in Subjects With Pruritus Associated With Atopic Dermatitis (SOOTHE)

Pruritus | Atopic Dermatitis
TauRx Therapeutics Ltd

Completed

Open Label Study of TRx0014 in Alzheimer's Disease

Alzheimer's Disease
Atopix Therapeutics, Ltd.

Completed

Effect of OC000459 on Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

United Kingdom
TauRx Therapeutics Ltd

Completed

Safety and Efficacy Study Evaluating TRx0237 in Subjects With Mild Alzheimer's Disease

Alzheimer's Disease

United States, Spain, Canada, Belgium, France, Italy, Croatia, Finland, Germany, United Kingdom, Australia, Netherlands
Canbex Therapeutics Ltd

Completed

Study of VSN16R for the Treatment of Spasticity in Multiple Sclerosis

Spasticity in People With Multiple Sclerosis

United Kingdom
Revive Therapeutics, Ltd.

Unknown

Bucillamine Phase 2 Trial in Patients With Cystinuria

Cystinuria

United States
Opsona Therapeutics Ltd.

Completed

Placebo-Controlled Study to Evaluate the Safety and Efficacy of OPN-305 in Preventing Delayed Renal Graft Function

Delayed Graft Function

United States, Spain, Belgium, Switzerland, France, Germany, United Kingdom, Poland, Netherlands, Austria, Czech Republic
Vensica Therapeutics Ltd.
Blueclinical, Ltd.

Completed

Clinical Trial for the Assessment of Safety, Usability and Efficacy of the Vixe Combination for OAB in Female Subjects (XAVIER)

Overactive Bladder

Portugal
NCIC Clinical Trials Group
Cascadian Therapeutics Inc.

Completed

A Study of PX-866 in Patients With Glioblastoma Multiforme at Time of First Relapse or Progression

Glioblastoma

Canada
Windtree Therapeutics
CVie Therapeutics Co. Ltd.

Completed

The Clinical Study of the Safety and Efficacy of Istaroxime in Treatment of Acute Decompensated Heart Failure

Acute Decompensated Heart Failure

China, Italy
United Therapeutics
CVie Therapeutics Co. Ltd.

Withdrawn

An Open Label Extension Study to Evaluate the Safety of Continued Therapy of Subcutanous Remodulin® in Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

China

Clinical Trials Sponsored by Circadian Therapeutics Ltd

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