Clinical Trials Sponsored by Cyclerion Therapeutics

Total 6332 results

RAI Services Company
Celerion

Completed

CSD190101: A Study to Assess Nicotine Pharmacokinetic Parameters After Use of Two Smokeless Tobacco Products

Tobacco Use

United States
Promentis Pharmaceuticals, Inc.
Celerion

Completed

Placebo-Controlled Single Dose Study to Evaluate Safety and Pharmacokinetics of SXC-2023 in Healthy Volunteers

Healthy

United States
Madrigal Pharmaceuticals, Inc.
Celerion

Completed

Bioavailability Study of MGL-3196 Tablets Compared to Capsules

Healthy

United States
Madrigal Pharmaceuticals, Inc.
Celerion

Completed

Drug Interaction Study of MGL-3196 With Rosuvastatin and Simvastatin

Healthy

United States
Afferent Pharmaceuticals, Inc.
Celerion

Completed

A Study to Assess the Effect of Intragastric pH and Fasting on the Pharmacokinetics of Gefapixant (AF-219/MK-7264)

Healthy Volunteers
2A Pharma AB
Celerion

Completed

A Study of Safety, Tolerability and Immunogenicity of HPV-L2 Vaccine in Healthy Adult Male and Female Subjects

Papillomavirus Infections

United Kingdom
Helsinn Healthcare SA
Celerion

Completed

Study to Evaluate the Food Effect of Single-dose Bioavailability of Pracinostat in Healthy Adult Subjects (HVFE)

Healthy Volunteers | Non-smokers | Moderate to Heavy Smokers

United States
Lorillard Tobacco Company
Celerion

Completed

Characterization of Biomarkers of Tobacco Exposure, Urge-to-Smoke Following Exclusive and Dual Ad Lib Use of Electronic Cigarettes

Cigarette Smoking

United States
Afferent Pharmaceuticals, Inc.
Celerion

Completed

A Multiple-Dose Pharmacokinetics Study of Two Gefapixant (AF-219/MK-7264) Formulations

Healthy

United States
Oppilan Pharma Ltd
Celerion

Completed

A PK Dose Proportionality Study of OPL-002 in Healthy Volunteers

Healthy

United Kingdom
Alexza Pharmaceuticals, Inc.
Celerion

Completed

Staccato® Granisetron Multiple Dose PK

Healthy

United States
Alexza Pharmaceuticals, Inc.
Celerion

Completed

Staccato® Granisetron Single Dose PK

Healthy

United States
Neuropore Therapies Inc.
Celerion

Completed

A Study to Assess the Safety, Tolerability and PK of NPT520-34 in Healthy Subjects

Healthy Volunteers

United States
RAI Services Company
Celerion

Completed

CSD190103: A Study to Assess Nicotine Pharmacokinetic Parameters After Use of Two Smokeless Tobacco Products

Tobacco Use

United States
Wex Pharmaceuticals Inc.
Celerion

Completed

A Phase 1, Single Ascending Dose, Randomized, Double-Blind, Placebo and Positive Controlled Study to Evaluate the Cardiovascular Effect of Tetrodotoxin in Healthy Adult Subjects

TQT Study

United States
Adello Biologics, LLC
Celerion

Completed

Comparative Immunogenicity Study Comparing TPI-120 to Neulasta® in Healthy Adult Subjects (TPI-120)

Healthy Volunteers

United States
RAI Services Company
Celerion

Completed

CSD170401: Study to Assess Elements of Abuse Liability for Three Electronic Tobacco Vapor Products During an 11-Day In-Clinic Confinement

Smoking

United States
Madrigal Pharmaceuticals, Inc.
Celerion

Completed

Drug Interaction Study of MGL-3196 With Atorvastatin

Healthy

United States
Nantes University Hospital
Cyceron

Not yet recruiting

Evaluation of PET 18F-Fludarabine for the Initial Assessment and End-treatment of Symptomatic Multiple Myeloma Patients (Myelofludate)

Myeloma

France
University Hospital, Caen
Cyceron

Unknown

Conflict Detection Development During the Reasoning (DéCoR)

Healthy Volunteers

France
Mayo Clinic
Celerion; Anexon, Incorporated

Completed

ANX-042 Healthy Volunteer Dose Escalation Study

Healthy Volunteers

United States
Janssen Research & Development, LLC
Celerion

Completed

A Study to Determine the Effect of Food on the Pharmacokinetics of Erdafitinib in Healthy Participants

Healthy

United States
Altria Client Services LLC
Celerion

Recruiting

Pharmacokinetic and Subjective Effects of Heated Tobacco Products

Tobacco Use

United States
Altria Client Services LLC
Celerion

Recruiting

Changes in Biomarker of Exposure in Adults Who Smoke Cigarettes Switching From Cigarettes to Heated Tobacco Products

Tobacco Use

United States
medac GmbH
Syneos Health; Celerion

Completed

Treosulfan-based Conditioning in Paediatric Patients With Haematological Malignancies

Myelodysplastic Syndromes (MDS) | Acute Lymphoblastic Leukaemias (ALL) | Acute Myeloid Leukaemias (AML) | Juvenile Myelomonocytic Leukaemias (JMML)

Germany, United Kingdom, Italy, Austria, Czechia, Poland
F2G Biotech GmbH
Celerion Ltd

Completed

Study of Potential for Interaction of Fluconazole With F901318

Invasive Aspergillosis

United Kingdom
Ranok Therapeutics (Hangzhou) Co., Ltd.

Recruiting

A Study of RNK05047 in Subjects With Advanced Solid Tumors/Diffuse Large B-cell Lymphoma (CHAMP-1)

Advanced Solid Tumor | DLBCL

United States
Otsuka Pharmaceutical Factory, Inc.
Celerion

Completed

Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Food Effect of NO-13065 in Healthy and Obese Adult Subjects

Obesity

United States
22nd Century Group, Inc.
Celerion

Completed

A Study to Assess Changes in Cigarette Consumption During a Switch to Very Low Nicotine Cigarettes

Tobacco Use

United States
Merck Sharp & Dohme LLC
Celerion

Completed

The Influence of Hepatic Insufficiency on the Pharmacokinetics of Elbasvir (MK-8742) (MK-8742-009)

Hepatic Insufficiency

United States
British American Tobacco (Investments) Limited
Celerion

Active, not recruiting

BAT3221032: A Study to Evaluate the Effects of Switching From Cigarette Smoking to Using One of Five Variants of a Heated Tobacco Product on Biomarkers of Exposure and Biomarkers of Potential Harm in Healthy Subjects

Smoking | Tobacco Use | Tobacco Smoking

United States
FUJIFILM Toyama Chemical Co., Ltd.
Celerion

Completed

PK Study of T-817 in Subjects With Hepatic Impairment

Healthy | Hepatic Impairment

United States
Eikon Therapeutics
Impact Therapeutics, Inc.

Recruiting

A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors

Advanced Solid Tumor

Australia, United States
APRINOIA Therapeutics, LLC

Active, not recruiting

A First-in-Human Study to Assess Single Doses of APNmAb005 in Healthy Participants

Alzheimer Disease | Tauopathies | Healthy Volunteers

United States
CRISPR Therapeutics AG

Active, not recruiting

A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refractory Renal Cell Carcinoma (COBALT-RCC)

Renal Cell Carcinoma

United States, Australia, Canada, Netherlands
CRISPR Therapeutics AG

Recruiting

A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed or Refractory Solid Tumors

Clear Cell Renal Cell Carcinoma | Pancreatic Adenocarcinoma | Cervical Carcinoma | Malignant Pleural Mesothelioma | Esophageal Carcinoma

United States
CRISPR Therapeutics AG

Active, not recruiting

A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refractory T or B Cell Malignancies (COBALT-LYM)

T Cell Lymphoma

United States, Australia, Canada
CRISPR Therapeutics AG

Active, not recruiting

A Safety and Efficacy Study Evaluating CTX110 in Subjects With Relapsed or Refractory B-Cell Malignancies (CARBON)

B-cell Lymphoma | Non-Hodgkin Lymphoma | B-cell Malignancy | Adult B Cell ALL

United States, Spain, Canada, France, Germany, Australia
Bacainn Therapeutics, Inc.

Completed

A Phase 1, Single-Ascending-Dose Study of BT051 in Healthy Subjects

Healthy Volunteers

United States
Celsus Therapeutics PLC

Terminated

Double-Blind, Trial to Evaluate the Safety and Efficacy of MRX-6 Cream 2% (C012013)

Atopic Dermatitis

Israel
Medical Device Works NV SA
Celerion; Cromsource

Unknown

Liver-PILP First-in-Man (PILP FiM)

Liver Metastases

Belgium
CRISPR Therapeutics AG

Recruiting

A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies

Follicular Lymphoma | B-cell Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Non-Hodgkin Lymphoma | B-cell Malignancy | Large B-cell Lymphoma | Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

United States
CRISPR Therapeutics AG

Enrolling by invitation

A Long-term Follow-up Study of Subjects Who Received CRISPR CAR T Cellular Therapies

Hematologic Malignancy | Solid Malignancy

United States
CRISPR Therapeutics AG

Active, not recruiting

A Safety and Efficacy Study Evaluating CTX120 in Subjects With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma

United States, Spain, Australia, Canada
APRINOIA Therapeutics, LLC

Active, not recruiting

Evaluation of [18F]APN-1607 PET Uptake in Alzheimer's Disease Patients Compared With Healthy Subjects

Healthy Volunteers | Alzheimer's Disease | Mild Cognitive Impairment Due to Alzheimer's Disease

United States
Skyline Therapeutics (US) Inc.

Recruiting

Phase I/II Study of SKG0106 Intravitreal Injection in Patients With Neovascular Age-related Macular Degeneration (nAMD)

Neovascular Age-related Macular Degeneration

China, United States
iCell Gene Therapeutics
iCar Bio Therapeutics

Recruiting

CD7 CAR-T Cell Treatment of Relapsed/Refractory CD7+ T -Acute Lymphoblastic Leukemia/ Lymphoma

Relapsed/Refractory, High Risk Hematologic Malignancies | T-ALL/Lymphoma

China
CRISPR Therapeutics AG
ViaCyte

Recruiting

An Open-Label, FIH Study Evaluating the Safety, Tolerability, and Efficacy of VCTX211 Combination Product in Subjects With T1D

Glucose Metabolism Disorders | Immune System Diseases | Autoimmune Diseases | Diabetes Mellitus | Endocrine System Diseases | Diabetes Mellitus, Type 1 | Metabolic Disease

Canada
iCell Gene Therapeutics
iCar Bio Therapeutics

Not yet recruiting

Anti-CD33 CAR-T Cells for the Treatment of Relapsed/Refractory CD33+ Acute Myeloid Leukemia

High Risk Hematologic Malignancies | Relapsed and/or Refractory Acute Myeloid Leukemia

China
Melinta Therapeutics, LLC

Recruiting

Open-Label, Dose-Finding, Pharmacokinetics, Safety and Tolerability Study of Oritavancin in Pediatric Patients With Suspected or Confirmed Bacterial Infections

Gram Positive Bacterial Infections

United States

Clinical Trials Sponsored by Cyclerion Therapeutics

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Lithuania

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations