Clinical Trials Sponsored by Helena DOMINGUEZ

Total 445 results

Regina Elena Cancer Institute

Recruiting

Prognostic Relevance of Coagulation Activation in RIsk Assessment and Stratification (ARIAS)

Local Cancer

Italy
Regina Elena Cancer Institute

Recruiting

Valveless Trocar Versus Standard Trocar in Robot-assisted Complex Partial Nephrectomy

Cancer of Kidney

Italy
Regina Elena Cancer Institute

Completed

Glioma: Biomolecular Aspects (GLIOMA)

Glioma, Malignant

Italy
Regina Elena Cancer Institute

Unknown

Transpulmonary Pressure Under Stressing Conditions

Ventilator-Induced Lung Injury

Italy
Regina Elena Cancer Institute

Completed

Sevoflurane Protective Effect on Ischemia-reperfusion Injury. Multicenter, Randomized Controlled Trial

Microsurgical Free Flaps

Italy
Regina Elena Cancer Institute

Completed

Clinical Outcomes and Costs Analyses in Use of Goal Directed Therapy

Postoperative Complications

Italy
Regina Elena Cancer Institute

Completed

Determination of Predictive Genetic Markers of Toxicity After Hypofractionated Radiotherapy in Breast Cancer Patients Post-Conservative Surgery (HYPOPRONE)

Breast Cancer

Italy
Helwan University

Not yet recruiting

New Method to Close Nasal Septal Perforation

Nasal Perforated Septum

Egypt
Helwan University

Not yet recruiting

Efficacy of Using 50 ml Syringe Manual Thrombectomy Catheter in Primary PCI With Heavy Thrombus Burden

STEMI - ST Elevation Myocardial Infarction | Thrombosis Cardiac

Egypt
Helwan University

Recruiting

The Effect of NAC in Decreasing the Incidence of Linezolid-induced Thrombocytopenia in Critically Ill Patients

Linezolid Induced Thrombocytopenia

Egypt
Helwan University

Completed

Safety and Efficacy of Triple and Quadruple Regimens as First Line Therapy for Management of Helicobacter Pylori Infection in Egyptians

H.Pylori Infection

Egypt
Helwan University

Active, not recruiting

Dapagliflozin in the Treatment of Heart Failure

Heart Failure

Egypt
Helwan University

Completed

Prevention of Cefoperazone-induced Coagulopathy

Antibiotic Side Effect

Egypt
Helwan University

Completed

Dexmedetomidine vs Fentanyl on Time to Extubation in Patients Undergoing Laparoscopic Sleeve Gastrectomy

Morbid Obesity | Dexmedetomidine | Laparoscopic Sleeve Gastrectomy | Fentanyl | Time to Extubation

Egypt
Helwan University

Completed

Sensitivity of Multiparametric MRI in Differentiation Between Muscle Invasive and Non-muscle Invasive Urinary Bladder Cancer

Cancer, Bladder

Egypt
Helwan University

Completed

Biologics in Management of Inflammatory Bowel Disease in Egyptian Patients

IBD

Egypt
Helwan University

Completed

Combined Ribavirin With Sofosbuvir/Velpatasvir/Voxilaprevir in Retreatment of Chronic Hepatitis C Non-responders

Chronic Hepatitis C

Egypt
Helwan University

Completed

Prostate Bipolar Enucleation and Resection Versus Open Prostatectomy

Benign Prostatic Hyperplasia

Egypt
Allena Pharmaceuticals

Completed

ALLN-346 Single Ascending Dose (SAD) Study in Healthy Volunteers (SAD)

Hyperuricemia

United States
Helwan University

Completed

Incidence of Paroxysmal Atrial Fibrillation (AF) in Patients With Acute Ischemic Stroke or Transient Ischemic Attacks (TIAs) by 48 Hours Holter Monitoring

Transient Ischemic Attack

Egypt
Allena Pharmaceuticals

Completed

Evaluate ALLN-177 in Patients With Enteric Hyperoxaluria

Enteric Hyperoxaluria

United States, Spain, United Kingdom, Germany, Canada, Italy, France
Allena Pharmaceuticals

Completed

Evaluating ALLN-177 for Reducing Urinary Oxalate Excretion in Calcium Oxalate Kidney Stone Formers With Hyperoxaluria

Nephrolithiasis | Hyperoxaluria

United States
Allena Pharmaceuticals

Completed

Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients With Secondary Hyperoxaluria and Kidney Stones Over 28 Days

Nephrolithiasis | Kidney Stones | Hyperoxaluria | Secondary Hyperoxaluria | Dietary Hyperoxaluria

United States
Helwan University

Recruiting

Drug Nephrotoxicity Amelioration by N-acetylcysteine

Drug-Induced Nephropathy

Egypt
Helwan University

Enrolling by invitation

Self-Fixating Mesh Versus Mesh Fixation With Tissue Glue in Laparoscopic Inguinal Hernia Repair

Inguinal Hernia

Egypt
Helwan University

Active, not recruiting

The Impact of Oral Vitamin C in Prevention for Post Operative Atrial Fibrillation (POAF) in Coronary Artery Bypass Surgery (CABG) Patients

Post Operative Atrial Fibrillation

Egypt
Helwan University

Completed

A Comparative Study Between Concomitant Versus Load Therapy in Eradication of Helicobacter Pylori Infection

H. Pylori Infection

Egypt
Helwan University

Completed

Intrathecal Injection of Hyperbaric Bupivacaine Versus a Mixture of Hyperbaric and Isobaric Bupivacaine in Patients Undergoing Lower Abdominal Surgery

Spinal Anesthesia | Lower Abdominal Surgery | Hyperbaric Bupivacaine | Isobaric Bupivacaine

Egypt
Allena Pharmaceuticals

Completed

An Inpatient Study of ALLN-346 (Engineered Urate Oxidase) in Hyperuricemic Subjects (Study 201)

Chronic Kidney Diseases | Hyperuricemia | Gout

United States
Helwan University

Completed

NONSPECIFIC NECK PAIN

Non Specific Neck Pain

Egypt
Helwan University

Completed

MicroPulse Transscleral Laser Cyclophotocoagulation With the Zig Zag Mode in Glaucoma.

Refractory Glaucoma

Egypt
Allena Pharmaceuticals

Terminated

Establishing the Safety and Efficacy of Reloxaliase in Patients With Enteric Hyperoxaluria (URIROX-2)

Enteric Hyperoxaluria

United States, Spain, United Kingdom, Portugal, Romania, Canada, Austria, Belgium, Brazil, Croatia, France, Germany, Italy, Mexico, Russian Federation, Switzerland
Weleda AG

Unknown

Bryophyllum vs. Nifedipine

Tocolysis

Switzerland
Helwan University

Recruiting

Role of Calcium Chloride Injection in Alleviating Atrial Fibrillation Post CABG

Atrial Fibrillation

Egypt
Helwan University

Not yet recruiting

Palbociclib in Metastatic Breast Cancer: Gene Polymorphism-based Study in Egyptian Patients. (Palbociclib)

Metastatic Breast Cancer | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | Hormone-receptor-positive Breast Cancer
Helwan University

Not yet recruiting

The Effect of PRP on Wound Healing in High Risk Patients Undergoing Abdominal Hysterectomy

Wound Heal | PRP | Abdominal Wound
Helwan University

Recruiting

Efficacy of Phentolamine in Prevention of Contrast-Associated Acute Kidney Injury After Complex PCI

Coronary Artery Disease | Acute Coronary Syndrome | Adrenergic Receptor Antagonist Adverse Reaction | CA-AKI - Contrast-Associated Acute Kidney Injury

Egypt
Helwan University

Recruiting

The Incidence of Linezolid-induced Thrombocytopenia (LIT) in Critically Ill Patients, the Risk Factors for LIT

Thrombocytopenia; Drugs

Egypt
Helwan University

Recruiting

Colchicine Protective Effect in Patients Undergoing Percutaneous Coronary Intervention (COLCHICINE-PROTECT)

Coronary Artery Disease

Egypt
Helwan University

Completed

Dexmedetomidine Versus Fentanyl on Postoperative Analgesic Profile in Laparoscopic Sleeve Gastrectomy

Pain, Postoperative

Egypt
Helwan University

Completed

Efficacy and Tolerability of Lubiprostone in Patients With Nonalcoholic Fatty Liver Disease

NAFLD

Egypt
Helwan University

Completed

Role of NFKBIA and PTPN22 Genes Polymorphism in Acute Rejection Susceptibility After Living Donor Liver Transplantation in Egyptian Patients.

Liver Transplant Rejection

Egypt
Helwan University

Active, not recruiting

Long Term Follow up of Water Vapor Thermal Therapy (Rezum) for Benign Prostatic Hyperplasia (BPH)

Benign Prostatic Hyperplasia

Egypt
Allena Pharmaceuticals

Terminated

Phase IIa Study of ALLN-346 (Engineered Urate Oxidase) in Subjects With Hyperuricemia, Gout and Chronic Kidney Disease

Chronic Kidney Diseases | Hyperuricemia | Gout

United States
Helwan University

Completed

Erythropoiesis Stimulating Agents for Anemia Management in Egyptian Hemodialysis Patients

Anemia of Chronic Kidney Disease | Chronic Renal Failure | Chronic Renal Failure Anemia

Egypt
Helwan University

Completed

Statins in Patients With Type 2 Diabetes Mellitus and Previous History of Acute Coronary Syndrome

Diabetes Mellitus | Hydroxymethylglutaryl-CoA Reductase Inhibitors

Egypt
Allena Pharmaceuticals

Completed

A Pilot Study of Oxalate Absorption in Secondary Hyperoxaluria

Nephrolithiasis | Kidney Stones | Hyperoxaluria | Secondary Hyperoxaluria

United States
Allena Pharmaceuticals

Completed

Study 102: Multiple Ascending Dose Study of ALLN-346 (Engineered Urate Oxidase) (MAD)

Hyperuricemia | Gout

United States
Hemera Biosciences

Withdrawn

Intravitreal AAVCAGsCD59 for Advanced Dry Age-related Macular Degeneration (AMD) With Geographic Atrophy (GA)

Geographic Atrophy | Dry Age-related Macular Degeneration | Gene Therapy | Intravitreal Injection
Helwan University

Completed

The Incidence of Gall Stones After Bariatric Surgery and Its Association With Weight Loss

The Incidence of Gall Stones After Bariatric Surgery and Its Association With Weight Loss

Egypt

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