Clinical Trials Sponsored by Institut fur Klinische Forschung, Germany

Total 304 results

Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

The ABC-HCC Trial: Atezolizumab Plus Bevacizumab vs. Transarterial Chemoembolization (TACE) in Intermediate-stage HepatoCellular Carcinoma

Hepatocellular Carcinoma

Austria, Germany, Spain, Japan, Italy, France
Institut für Klinische Krebsforschung IKF GmbH...

Active, not recruiting

Chemotherapy and Pembrolizumab, Followed by Pembrolizumab and Olaparib as Firstline Therapy in Her-2 Negative Gastric/GEJ Adenocarcinoma

Esophagogastric Adenocarcinoma

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Completed

Ramucirumab Plus TAS-102 in Patients With Advanced or Metastatic Gastric Adenocarcinoma or the Gastroesophageal Junction (RE-ExPEL)

Gastric Adenocarcinoma | Metastatic Adenocarcinoma of the Gastroesophageal Junction

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Completed

Study With Cabazitaxel in Previously Treated Patients With Advanced or Metastatic Gastric Cancer

Gastric Cancer

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Medizinische Hochschule Hannover, Germany, Prof. Dr. Arndt Vogel; MSD Sharp...

Not yet recruiting

Efficacy and Safety of GemCis Plus Trastuzumab Plus Pembrolizumab in Previously Untreated HER2-positive Biliary Tract Cancer (TRAP-BTC)

Biliary Tract Cancer | HER2 Gene Mutation
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

Feasibility and Safety of IMP321 (Eftilagimod Alpha) for Advanced Stage Solid Tumors

Solid Tumors | Peritoneal Carcinomatosis

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Active, not recruiting

Advancing Brigatinib Properties in ALK+ NSCLC Patients by Deep Phenotyping

NSCLC

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Active, not recruiting

Modified FOLFOX Plus/Minus Nivolumab and Ipilimumab vs. FLOT Plus Nivolumab in Patients With Previously Untreated Advanced or Metastatic Gastric Cancer

GastroEsophageal Cancer | Adenocarcinoma of the Stomach

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Terminated

Trial Comparing Parenteral Nutrition (PN) Using Eurotubes® vs. 2/3-chamber Bags in Subjects With Solid Tumors Requiring PN (PEKANNUSS) (PEKANNUSS)

Solid Tumor

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Terminated

CaboCHECK - Cabozantinib in Adult Patients With Advanced Renal Cell Carcinoma Following Prior Systemic Check Point Inhibition Therapy: a Retrospective, Non-interventional Study

Advanced Renal Cell Carcinoma (All Subtypes) | Metastatic Renal Cell Carcinoma (All Subtypes)

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Completed

FLOT vs. FLOT/Ramucirumab for Perioperative Therapy of Gastric or GEJ Cancer (RAMSES) (RAMSES/FLOT7)

Stomach Cancer | Gastroesophageal Junction Cancer

Germany, Italy
North Eastern German Society of Gynaecological...
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest

Not yet recruiting

A Phase II Randomized, Open Label Non-inferiority Study of NiraParib Maintenance After 3 vs. 6 Cycles of Platinum-based Chemotherapy in completeLy debUlked Advanced HRDpositive High-grade Ovarian Cancer patientS in First Line Therapy (N-Plus)

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Carcinoma | Clear Cell Carcinoma
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

Discontinuation of CDK4/6 Inhibitors in Patients With Metastatic HR Positive, HER2 Negative Breast Cancer

Breast Cancer

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

Organ Preservation With Durvalumab-based Immunotherapy in Combination With Chemoradiation as Definitive Therapy for Early Stage Esophageal Adenocarcinoma With Indication for Radical Surgery

Esophagus Adenocarcinoma

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

Treatment of Atezolizumab and Derazantinib in Patients With Advanced iCCA With FGFR2 Fusions/Rearrangements

Intrahepatic Cholangiocarcinoma

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

GISAR German Interdisciplinary Sarcoma Registry (GISAR)

Sarcoma | Carcinosarcoma | Sarcoma,Soft Tissue | Sarcoma of Bone

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

Ramucirumab Plus FOLFIRI Versus Ramucirumab Plus Paclitaxel in Patients With Advanced or Metastatic Gastric Cancer, Who Failed One Prior Line of Palliative Chemotherapy (RAMIRIS)

Advanced Gastric or EGJ Cancer

Germany, Austria, Italy
Institut für Klinische Krebsforschung IKF GmbH...

Active, not recruiting

Comprehensive Genomic Profiling Combined With Real Life Data of "The German-Registry of Incidental Gallbladder Carcinoma"

Gallbladder Carcinoma

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Active, not recruiting

Immunotherapy With Durva and Treme With or Without Capecitabine in Adjuvant Treatment for Biliary Tract Cancer

Intrahepatic Cholangiocarcinoma | Hilar Cholangiocarcinoma | Distal Cholangiocarcinoma | Gall Bladder Carcinoma | Biliary Tract Cancer (CCA)

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Active, not recruiting

IMMULAB - Immunotherapy With Pembrolizumab in Combination With Local Ablation in Hepatocellular Carcinoma (HCC)

Hepatocellular Carcinoma (HCC)

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Completed

Intravenous Ferric Carboxymaltose vs. Oral Iron Substitution in Patients With Metastatic Colorectal Cancer (CRC) and Iron Deficiency Anemia: a Randomized Multicenter Treatment Optimization Study.

Metastatic Colorectal Cancer

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Terminated

OlaReDo - Olaratumab and Rechallenge With Doxorubicin in Soft Tissue Sarcoma Patients

Advanced Soft Tissue Sarcoma

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Ipsen

Recruiting

Cabozantinib for Patients With Hepatocellular Carcinoma (HCC) Refractory to First Line Treatment

Hepatocellular Carcinoma Non-resectable | Metastatic Hepatocellular Carcinoma

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Charite University, Berlin, Germany; Roche Pharma AG; Hoffmann-La Roche; Arbeitsgemeinschaft... and other collaborators

Recruiting

Rituximab in Combination With Glofitamab and Polatuzumab Vedotin in Patients With Previously Untreated Aggressive B-cell Lymphoma Ineligible for R-CHOP (R-Pola-Glo)

Lymphoma, Large B-Cell, Diffuse

Germany, Austria
German Institute of Human Nutrition
Charite University, Berlin, Germany; Freie Universität Berlin; German Center...

Recruiting

Breathing and Decision-Making (ProlEx-MRI)

Quality of Life | Stress, Psychological | Behavior

Germany
Nikolaj Frost MD
Roche Pharma AG; Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus...

Recruiting

Pemetrexed-free vs. Pemetrexed-based Immunochemotherapy in Metastatic TTF-1 Negative Lung Adenocarcinoma (ANTELOPE)

Non-Small Cell Lung Cancer Metastatic

Germany
Institut für Klinische Krebsforschung IKF GmbH...
PharmaMar

Recruiting

Prospective Study to Evaluate Patient Reported Outcomes (PRO) During Rechallenge With Trabectedin in Sarcoma Patients (PROTraSarc)

Soft Tissue Sarcoma

Germany
Institut für Klinische Krebsforschung IKF GmbH...
AstraZeneca

Recruiting

Immunotherapy Combined With Y-90 SIRT Therapy in Advanced Stage Intrahepatic Biliary Tract Cancer (BTC)

Intrahepatic Cholangiocarcinoma

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Celgene

Completed

PARAGON Platform for Outcome, Quality of Life, and Translational Research on Pancreatic Cancer (PARAGON)

Pancreatic Adenocarcinoma

Germany
University Hospital Heidelberg
The German Heart Foundation; Apple Inc.; Deutsches Zentrum für Herz-Kreislauf-Forschung... and other collaborators

Recruiting

activeDCM - Interventional Clinical Trial of Individualized Activity and Exercise Programs to Improve Outcome in Dilated Cardiomyopathy Guided by Longitudinal Biosensing With Apple Watch (ACTIVE-DCM)

Heart Failure | Cardiomyopathy, Dilated

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Gilead Sciences

Recruiting

Study Evaluating Treatment of Sacituzumab-govitecan for Patients With Metastatic Esophagogastric Adenocarcinoma

Esophagogastric Adenocarcinoma

Germany, Austria
Universitätsklinikum Hamburg-Eppendorf
Federal Joint Committee; aQua-Institut GmbH, Germany; Leibniz-Institut für Resilienzforschung... and other collaborators

Active, not recruiting

Family Health Partners in Regional Network Structures (NEST)

Disabled or Chronically Ill Children in Need of Care

Germany
German Heart Institute
University Medicine Greifswald; Helmholtz Zentrum München; University of Göttingen and other collaborators

Active, not recruiting

Early Versus Emergency Left Ventricular Assist Device Implantation in Patients Awaiting Cardiac Transplantation

End Stage Heart Disease

Germany
North Eastern German Society of Gynaecological...
Clovis Oncology, Inc.; Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus...

Active, not recruiting

Rucaparib MAintenance After Bevacizumab Maintenance Following Carboplatin Based First Line Chemotherapy in Ovarian Cancer Patients (MAMOC)

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer | Clear Cell Carcinoma

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Merck Sharp & Dohme LLC; Medizinische Hochschule Hannover, Germany, Prof. Dr...

Active, not recruiting

Pembrolizumab and Lenvatinib in Patients With Advanced HCC Who Are Refractory to Atezolizumab and Bevacizumab/ IO-based Therapy

Hepatocellular Carcinoma

Germany
University of Luebeck
European Commission; Deutsche Stiftung für Herzforschung; Deutsches Zentrum für... and other collaborators

Completed

Culprit Lesion Only PCI Versus Multivessel PCI in Cardiogenic Shock (CULPRIT-SHOCK)

Complications | Acute Myocardial Infarction | Cardiogenic Shock

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Thoraxklinik-Heidelberg gGmbH

Active, not recruiting

Thoracic RadiothErapy With Atezolizumab in Small Cell lUng canceR Extensive Disease (TREASURE)

Thoracic Radiotherapy | Small Cell Lung Cancer Extensive Stage

Germany, Austria
ViMREX GmbH
Frankfurter Institut für Klinische Krebsforschung IKF GmbH am Krankenhaus...

Active, not recruiting

Clinical Trial With Local Decitabine Treatment of HPV-Induced VIN Grade 2/3 (DelVIN) (DelVIN)

Vulvar Intraepithelial Neoplasia Grade 2 | Vulvar Intraepithelial Neoplasia Grade 3

Germany
Charite University, Berlin, Germany
Boston Scientific Corporation; Deutsches Zentrum für Herz-Kreislauf-Forschung... and other collaborators

Recruiting

CAtheter-Based Ablation of Atrial Fibrillation Compared to Conventional Treatment in Patients With Heart Failure With Preserved Ejection Fraction (CABA-HFPEF)

Atrial Fibrillation | Heart Failure With Preserved Ejection Fraction | Heart Failure With Mildly Reduced Ejection Fraction

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Roche Pharma AG

Recruiting

Study of Atezolizumab + FLOT vs. FLOT Alone in Patients With GC/GEJ and High Immune Responsiveness (DANTE)

Gastric Cancer | Gastroesophageal Junction Adenocarcinoma

Germany, Switzerland
University Hospital Heidelberg
Institut für Klinische Krebsforschung IKF GmbH am Krankenhaus Nordwest

Completed

Combined PD-1 and CCR5 Inhibition for the Treatment of Refractory Microsatellite Stable mCRC (PICCASSO)

Metastatic Colorectal Cancer | MSS

Germany
German Institute of Human Nutrition
California Walnut Commission; German Center for Diabetes Research; Institute...

Unknown

POLY-unsaturated Fatty Acids in the Preservation of Dietary Effects on Hepatosteatosis and Energy Metabolism in Type 2 Diabetes (POLYPHEM)

Hypertension | Obesity | Metabolic Syndrome | Type 2 Diabetes | Dyslipidemia | NAFLD

Germany
German Institute of Human Nutrition
German Center for Diabetes Research; Institute for Cereal Processing GmbH/Institut... and other collaborators

Unknown

Diabetes Nutrition Algorithms in Patients With Overt Diabetes Mellitus (DiNA-D)

Hypertension | Obesity | Type 2 Diabetes | NAFLD | Dyslipoproteinaemia

Germany
Max Planck Institute for Human Cognitive and Brain...
Universitätsklinikum Leipzig; DFG - Deutsche Forschungs Gemeinschaft (German... and other collaborators

Recruiting

Impact of Microbiome-changing Interventions on Food Decision-making (MIFOOD)

Overweight and Obesity

Germany
Institut für Klinische Krebsforschung IKF GmbH...
EUSA Pharma, Inc.

Recruiting

Treatment With Dinutuximab Beta, Zoledronic Acid and Low-dose Interleukin (IL-2) in Patients With Leiomyosarcoma (DiTuSarc)

Leiomyosarcoma

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Roche Pharma AG

Recruiting

PLATON - Platform for Analyzing Targetable Tumor Mutations (Pilot-study) (PLATON)

Stomach Cancer | Pancreatic Cancer | Cholangiocarcinoma | Gallbladder Cancer | Hepatocellular Cancer | Oesophageal Cancer

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Bristol-Myers Squibb

Active, not recruiting

Nivolumab With Chemotherapy in Pleural Mesothelioma After Surgery

Pleural Mesothelioma Malignant

Germany
Carsten Müller-Tidow
German Federal Ministry of Education and Research; Institut für Klinische Transfusionsmedizin...

Recruiting

Trial With or Without Infusion of SARS-CoV-2 Antibody Containing Plasma in High-Risk Patients With COVID-19 (RECOVER)

SARS-CoV-2 Infection

Germany
Institut für Klinisch-Kardiovaskuläre Forschung...
AstraZeneca; Boehringer Ingelheim; Amgen; Sanofi-Aventis Deutschland GmbH; BMBf (Federal... and other collaborators

Unknown

Coronary Artery Disease and Renal Failure Registry (CAD-REF)

Coronary Artery Disease | Renal Failure

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Incyte Biosciences International Sàrl

Recruiting

Pemigatinib After Curative Local Therapy in Advanced iCCA With FGFR2 Fusion/Rearrangements

Intrahepatic Cholangiocarcinoma | FGFR2 Gene Mutation | FGFR2 Gene Translocation | FGFR2 Gene Rearrangement

Germany

Clinical Trials Sponsored by Institut fur Klinische Forschung, Germany

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