Clinical Trials Sponsored by Kronos+Bio

Total 2411 results

IconOVir Bio

Recruiting

Safety and Tolerability of Intravenous Administration of ICVB-1042

Patients With Advanced Solid Tumors

United States
ImmPACT Bio

Recruiting

Study of IMPT-314 in R/R Aggressive B-cell NHL

Refractory Non-Hodgkin Lymphoma | Relapsed Non-Hodgkin Lymphoma

United States
Incyclix Bio

Recruiting

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer (INX-315-01)

Breast Cancer | Ovarian Cancer | Solid Tumor | Metastatic Cancer | Advanced Cancer | Breast Cancer Metastatic | Hormone Receptor Positive Tumor | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | CCNE1 Amplification

United States, Australia
Palisade Bio

Terminated

A Study to Evaluate LB1148 for Return of Bowel Function in Subjects Undergoing Bowel Resection (INTEGRITY)

Ileus | Gastro-Intestinal Disorder

United States
HI-Bio

Completed

Clinical Trial to Assess Efficacy and Safety of the Human Anti-CD38 Antibody Felzartamab (MOR202) in IgA Nephropathy (IGNAZ)

Immunoglobulin A (IgA) Nephropathy

United Kingdom, Germany, Spain, Serbia, Taiwan, Australia, Japan, Korea, Republic of, Belgium, United States, Bulgaria, Czechia, Georgia, Malaysia, Philippines, Ukraine
BenevolentAI Bio

Completed

Study Investigating the Safety, Tolerability, PK and Food Effect of BEN8744.

Healthy Volunteer Study

United Kingdom
Instil Bio

Terminated

ITIL-168 in Advanced Melanoma (DELTA-1)

Advanced Cutaneous Melanoma

United States, Canada, United Kingdom
bluebird bio

Active, not recruiting

Long-term Follow-up of Subjects With Transfusion-Dependent β-Thalassemia (TDT) Treated With Ex Vivo Gene Therapy

Transfusion-dependent Beta-Thalassemia

United States, France, United Kingdom, Australia, Thailand, Italy, Germany, Greece
bluebird bio

Completed

A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia

Beta-Thalassemia

United States, Germany, United Kingdom, France, Greece, Italy
Instil Bio

Active, not recruiting

ITIL-306 in Advanced Solid Tumors

Renal Cell Carcinoma | Epithelial Ovarian Cancer | Non-small Cell Lung Cancer

United States
HI-Bio

Completed

Efficacy, Safety and PK/PD of MOR202 in Anti-PLA2R + Membranous Nephropathy (aMN) (NewPLACE) (NewPLACE)

Glomerulonephritis | Membranous Nephropathy | antiPLA2R Positive

Taiwan, Korea, Republic of, Greece, Germany, United Kingdom, Georgia, Russian Federation
Baudax Bio

Completed

Evaluation of Intubation Conditions Following BX1000 or Rocuronium in Subjects Undergoing Surgery

Surgery | Anesthesia | Neuromuscular Blockade

United States
BenevolentAI Bio

Completed

A First-in-Human PoC Study With BEN2293 in Patients With Mild to Moderate Atopic Dermatitis

Atopic Dermatitis

United Kingdom
bluebird bio

Completed

A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia, Who do Not Have a β0/β0 Genotype

Beta-Thalassemia

France, United Kingdom, United States, Thailand, Italy, Germany
Baudax Bio

Completed

Evaluation of DEX-IN During Outpatient Procedures

Pain

United States
Baudax Bio

Completed

Evaluation of Preoperative N1539 in Total Knee Arthroplasty

Pain, Postoperative

United States
Mustang Bio

Enrolling by invitation

Long-term Follow-up Study in Patients Previously Treated With a Mustang Bio CAR-T Cell Investigational Product.

Diffuse Large B Cell Lymphoma | Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) | Hairy Cell Leukemia | Mantle Cell Lymphoma Recurrent | Mantle Cell Lymphoma Refractory | Chronic Lymphocytic Leukemia in Relapse | Small Lymphocytic Lymphoma, Relapsed | Waldenstrom's Macroglobulinemia Recurrent | Follicular B-cell Non-Hodgkin's Lymphoma and other conditions

United States
R-Bio

Completed

Follow-up Study for Participants Jointstem Clinical Trial

Knee Osteoarthritis

Korea, Republic of
bluebird bio

Terminated

Observational Study to Evaluate Allogeneic HSCT Outcomes for Cerebral Adrenoleukodystrophy (CALD)

Cerebral Adrenoleukodystrophy (CALD) | Adrenoleukodystrophy (ALD) | X-Linked Adrenoleukodystrophy (X-ALD)

United States, United Kingdom, Argentina, Canada, Germany, Italy, Netherlands
R-Bio

Completed

Autologous Adipose Tissue Derived Mesenchymal Stem Cells Transplantation in Patient With Degenerative Arthritis

Degenerative Arthritis

Korea, Republic of
R-Bio

Completed

Clinical Trial to Evaluate Efficacy and Safety of JOINTSTEM in Patients With Degenerative Arthritis

Knee Osteoarthritis | Degenerative Arthritis

Korea, Republic of
bluebird bio

Completed

A Study Evaluating the Safety and Efficacy of the LentiGlobin BB305 Drug Product in β-Thalassemia Major Participants

β-thalassemia Major

United States, Australia, Thailand
Motif Bio

Completed

Phase 3 Study to Evaluate Safety and Efficacy of Iclaprim Versus Vancomycin for ABSSSI: REVIVE-1 (REVIVE-1)

Skin Structures and Soft Tissue Infections

United States, Bulgaria, Chile, Colombia, Germany, Latvia, Peru, Poland, Puerto Rico, Ukraine
Baudax Bio

Completed

Evaluation of N1539 Following Abdominoplasty Surgery

Pain, Post-operative

United States
R-Bio

Completed

Autologous Adipose Derived MSCs Transplantation in Patient With Spinal Cord Injury. (MSC)

Spinal Cord Injury
Cabaletta Bio

Recruiting

RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis

Systemic Sclerosis | Scleroderma

United States
ImmPACT Bio

Recruiting

A Study of IMPT-514 in Active Refractory Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus | Lupus Nephritis

United States, Australia
Cabaletta Bio

Recruiting

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

Systemic Lupus Erythematosus | Lupus Nephritis

United States
HI-Bio

Recruiting

A Study of Felzartamab in Participants With Lupus Nephritis

Lupus Nephritis

United States, Argentina, Australia, Canada
Exegenesis Bio

Recruiting

A Study of EXG102-031 in Patients With wAMD (Everest)

Neovascular (Wet) Age-related Macular Degeneration (nAMD)

United States
Cabaletta Bio

Recruiting

Open-label Study to Evaluate the Safety of Various Dosing Regimens of MuSK-CAART for MuSK Myasthenia Gravis

MuSK Myasthenia Gravis

United States
R-Bio

Not yet recruiting

Follow-up Study for Participants of Jointstem Investigator Initiated Trial by Arthroscopy

Knee Arthritis | Degenerative Arthritis
R-Bio

Not yet recruiting

Investigator Initiated Trial to Evaluate Cartilage Regeneration by Arthroscopy After JOINTSTEM Administration

Knee Arthritis | Degenerative Arthritis

Korea, Republic of
Akamis Bio

Recruiting

First in Human Study With NG-641, a Tumour Selective Transgene Expressing Adenoviral Vector (STAR)

Metastatic Cancer | Epithelial Tumor

United States
Endevica Bio

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of TCMCB07 in Single and Multiple Ascending Doses in Health Subjects

Cachexia

United States
bluebird bio

Enrolling by invitation

Long-term Follow-up of Subjects With Sickle Cell Disease Treated With Ex Vivo Gene Therapy

Sickle Cell Disease

United States, France
2seventy bio

Completed

Study of bb21217 in Multiple Myeloma

Multiple Myeloma

United States
Vivacelle Bio

Active, not recruiting

VBI-S for the Treatment of Hypotension in Hypovolemic Septic Shock Patients

Sepsis | Septic Shock | Hypovolemia

United States
Baudax Bio

Terminated

Safety and Pharmacokinetics of N1539 in Children 2 to <17 Years of Age Following Surgery

Post Operative Pain

United States
Mustang Bio

Terminated

Trial to Evaluate the Safety and Efficacy of MB-102 in Patients With BPDCN.

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

United States
Baudax Bio

Completed

Evaluation of Preoperative N1539 in Colorectal Surgery

Pain, Postoperative

United States
Instil Bio

Withdrawn

ITIL-168 in Advanced Solid Tumors (DELTA-2)

Cervical Cancer | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma
Akamis Bio

Completed

First in Human Study of NG-350A (an Oncolytic Adenoviral Vector Which Expresses an Anti-CD40 Antibody) (FORTITUDE)

Metastatic Cancer | Epithelial Tumor

United States
bluebird bio

Completed

A Study Evaluating the Safety and Efficacy of LentiGlobin BB305 Drug Product in β-Thalassemia Major (Also Referred to as Transfusion-dependent β-Thalassemia [TDT]) and Sickle Cell Disease

Sickle Cell Disease | Beta-Thalassemia Major

France
R-Bio

Completed

Investigator Initiated Trial to Evaluate the Efficacy and Safety of Intra-articular Injection of ADMSC Comared to Negative Control After High Tibial Osteotomy in the Osteoarthritis Patients.

Knee Osteoarthritis | Degenerative Arthritis

Korea, Republic of
Motif Bio

Completed

Phase 3 Study to Evaluate Safety and Efficacy of Iclaprim Versus Vancomycin for ABSSSI: REVIVE-2 (REVIVE-2)

Skin Structures and Soft Tissue Infections

United States, Argentina, Belgium, Croatia, Czechia, Estonia, Hungary, Portugal, Romania, Turkey
Baudax Bio

Completed

Evaluation of N1539 Following Bunionectomy Surgery

Pain, Post-operative

United States
Baudax Bio

Completed

Placebo-Controlled Evaluation of N1539 Following Bunionectomy Surgery

Pain, Post-operative

United States
S*BIO

Completed

A Phase I Dose Escalation Study of Oral SB939 Administered Alone or With Azacitidine

Myelodysplastic Syndrome | Solid Tumors | Hematologic Malignancies

United States, Singapore
S*BIO

Completed

A Single and Multiple-Dose Study of SB1578

Healthy Volunteer

United States

Clinical Trials Sponsored by Kronos+Bio

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