Clinical Trials Sponsored by Lotus Bio Inc.

Total 379 results

Tourmaline Bio, Inc.

Recruiting

A Study to Investigate Efficacy and Safety of TOUR006 in Participants 18 to 75 Years of Age With Thyroid Eye Disease (spiriTED)

Thyroid Eye Disease

United States, Jordan
Qlaris Bio, Inc.

Recruiting

Qlaris Phase 2 Study of QLS-111 in POAG and/or OHT Patients

Primary Open Angle Glaucoma of Both Eyes | Primary Open Angle Glaucoma (POAG) | Primary Open-Angle Glaucoma, Unspecified Eye | Ocular Hypertension (OHT)

United States
Belite Bio, Inc

Recruiting

Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Geographic Atrophy (PHOENIX)

Geographic Atrophy

United States, Taiwan, Australia, China, United Kingdom
Inmune Bio, Inc.

Recruiting

An Open-Label Extension of XPro1595 in Patients With Alzheimer's Disease

Mental Disorders | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Neurocognitive Disorders | Neurodegenerative Diseases | Dementia | Alzheimer Disease | Tauopathies

Australia, Canada
Daewoong Bio Inc.

Recruiting

Efficacy and Safety of ChOline ALfoscerate in Patient With Mild to Moderate Alzheimer's Disease (COALA)

Alzheimer Disease

Korea, Republic of
AmMax Bio, Inc.

Recruiting

A Study to Evaluate Safety and Efficacy of AMB-05X Injections in Subjects With TGCT

Tenosynovial Giant Cell Tumor | Pigmented Villonodular Synovitis | TGCT

Netherlands, Australia, United States
Nuvation Bio Inc.

Recruiting

NUV-868 as Monotherapy and in Combination With Olaparib or Enzalutamide in Adult Patients With Advanced Solid Tumors

Breast Cancer | Pancreatic Cancer | Ovarian Cancer | Prostate Cancer | Breast Carcinoma | Triple Negative Breast Cancer | Triple Negative Breast Neoplasms | Advanced Solid Tumor | Cancer of the Ovary | Pancreas Cancer | Triple-negative Breast Cancer | Cancer of Pancreas | Pancreas Neoplasm | Prostate Neoplasm | Cancer... and other conditions

United States, Australia
ABL Bio, Inc.

Recruiting

Study to Evaluate the Safety and Tolerability of ABL501, and to Determine the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D) of ABL501 in Subjects With Any Progressive, Locally Advanced (Unresectable) or Metastatic Solid Tumors

Advanced Solid Tumor

Korea, Republic of
Passage Bio, Inc.

Recruiting

A Study of PBFT02 in Patients With Frontotemporal Dementia and Progranulin Mutations (FTD-GRN) (upliFT-D)

Frontotemporal Dementia | FTD | Dementia Frontotemporal | FTD-GRN

United States, Brazil, Italy, Portugal, Canada
GID BIO, Inc.

Recruiting

Autologous Adipose-derived Stromal Vascular Fraction for Treatment of Knee Osteoarthritis

Osteoarthritis, Knee

United States
Inmune Bio, Inc.

Terminated

A Phase I Open-Label Dose Escalation Study of Intravenous INKmune In Patients With MDS or AML (LAUREL)

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Cancer | AML | MDS-EB

United Kingdom, Greece
Provention Bio, Inc.

Completed

Recent-Onset Type 1 Diabetes Trial Evaluating Efficacy and Safety of Teplizumab (PROTECT)

Type 1 Diabetes Mellitus

United States, Belgium, Canada, Czechia, France, Germany, Hungary, Poland, United Kingdom
Ocelot Bio, Inc

Completed

A Study of OCE-205 in Participants With Cirrhosis With Ascites Who Developed Hepatorenal Syndrome-Acute Kidney Injury

Cirrhosis | Ascites | Acute Kidney Injury | Hepatorenal Syndrome

United States, Canada
Takara Bio Inc.

Active, not recruiting

Study of TBI-1501 for Relapsed or Refractory Acute Lymphoblastic Leukemia (TBI-1501)

Lymphoblastic Leukemia, Acute Adult

Japan
Provention Bio, Inc.

Completed

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of PRV-3279 in Healthy Subjects (PREVAIL1)

Safety

United States
ReNetX Bio, Inc.

Completed

AXER-204 in Participants With Chronic Spinal Cord Injury (RESET)

Chronic Spinal Cord Injury

United States
Nuvation Bio Inc.

Withdrawn

Study of NUV-422 in Combination With Fulvestrant in Patients With HR+HER2- aBC

Breast Cancer | Advanced Breast Cancer | Metastatic Breast Cancer | Breast Carcinoma | Cancer of Breast | Malignant Tumor of Breast | Breast Tumor | Cancer of the Breast

United States
Upstream Bio Inc.

Completed

Safety and Blood Levels After a Single Injection of UPB-101 in Healthy Japanese and Non-Japanese Non-East Asian Adults

Healthy

United Kingdom
Qlaris Bio, Inc.

Completed

Safety and Tolerability Study of QLS-101 in Adolescents With Sturge-Weber Syndrome (SWS)-Related Glaucoma Due to Elevated Episcleral Venous Pressure (EVP)

Ocular Hypertension | Glaucoma | Sturge-Weber Syndrome

United States
Qlaris Bio, Inc.

Completed

Study to Evaluate QLS-101 Compared to Timolol Maleate Eye Drops in Subjects With High Eye Pressure (Glaucoma or Ocular Hypertension).

Primary Open Angle Glaucoma | Ocular Hypertension

United States
AmMax Bio, Inc.

Withdrawn

A Phase 2 Study to Evaluate Safety and Efficacy of AMB-05X in Subjects With Idiopathic Pulmonary Fibrosis

IPF
Goldfinch Bio, Inc.

Terminated

An Open-Label, Long-term Study of GFB-887 in Patients With Glomerular Kidney Diseases

Kidney Diseases | Glomerulonephritis | Nephritis | Nephrosis | Glomerulosclerosis | Focal Segmental Nephrosis | Lipoid Urologic Disease

United States
Goldfinch Bio, Inc.

Terminated

A Study of TRPC5 Channel Inhibitor in Patients With Diabetic Nephropathy, Focal Segmental Glomerulosclerosis, and Treatment-Resistant Minimal Change Disease

Kidney Diseases | Urologic Diseases | Diabetes Mellitus | Endocrine System Diseases | Diabetes Complications | Diabetic Nephropathies | Glomerulonephritis | Nephritis | Glomerulosclerosis, Focal Segmental | Nephrosis | Nephrosis, Lipoid

United States
Gritstone bio, Inc.

Completed

A Screening Study Targeting Tumor-specific Antigens

Metastatic Colorectal Cancer | Stage II/III Colon Cancer

United States
AmMax Bio, Inc.

Active, not recruiting

A Phase 2 Study of Intravenous AMB-05X in Tenosynovial Giant Cell Tumor Patients

Tenosynovial Giant Cell Tumor | Pigmented Villonodular Synovitis | TGCT | PVNS - Pigmented Villonodular Synovitis

Germany, Poland, Ukraine
Goldfinch Bio, Inc.

Completed

First-In-Human Study of GFB-024 in Healthy Overweight and Obese Participants, and Participants With Type 2 Diabetes

Kidney Diseases | Diabetes Mellitus | Endocrine System Diseases | Diabetes Complications | Diabetic Nephropathies

United States
Epirium Bio Inc.

Completed

Safety and Biomarker Response to (+)-Epicatechin in Becker Muscular Dystrophy

Becker Muscular Dystrophy

United States
Inmune Bio, Inc.

Terminated

INB03 for the Treatment of Pulmonary Complications From COVID-19

COVID-19

United States
Versanis Bio, Inc.

Completed

Variability of Physical Assessments in an Older Population That is Overweight or Obese

Obesity | Aging

United States
Belite Bio, Inc

Completed

Safety and Tolerability of Escalating Doses of BPN-14967 in Healthy Adults

Healthy Volunteers

United States
CTC Bio, Inc.

Completed

A Clinical Trial to Compare Pharmacokinetics of the "CDFF0318" and "Champix Tab. 1mg"

Smoking Cessation | Pharmacokinetics

Korea, Republic of
Sesen Bio, Inc.

Completed

Study of Vicinium for Treating Patients With Non-Invasive Urothelial Carcinoma In Situ

Urinary Bladder Cancer | Bladder Cancer | Bladder Neoplasms | Bladder Tumors

United States, Canada
Lexent Bio, Inc.

Terminated

Detection of Tumor DNA in Blood Samples From Patients With Early Stage Cancer and "Healthy Controls"

Neoplasms, Non-hematologic - Stage I-III

United States
Takara Bio Inc.

Completed

Study of HF10 in Patients With Refractory Head and Neck Cancer or Solid Tumors With Cutaneous and/or Superficial Lesions

Malignant Melanoma | Carcinoma of the Breast | Squamous Cell Carcinoma, Skin | Refractory Head and Neck Cancer

United States
Benovus Bio, Inc.

Unknown

Phase I Study of an Oncofetal Antigen Multi-Peptide Immunotherapy in Subjects With Hematologic Cancer (BBMPI03)

Myelodysplastic Syndrome (MDS) | Acute Myelogenous Leukemia (AML) | Multiple Myeloma (MM) | Smoldering Multiple Myeloma (sMM)

United States
Sesen Bio, Inc.

Terminated

Study of Proxinium Plus Best Supportive Care Versus Best Supportive Care for Patients With Advanced Head and Neck Cancer

Head and Neck Cancer | Head and Neck Neoplasms | Carcinoma, Squamous Cell | Neoplasms, Squamous Cell | Mouth Neoplasms | Carcinoma, Squamous Cell of Head and Neck

Spain, Germany, Israel, Italy, Poland, United Kingdom, India, Argentina, France, Hungary, Serbia, Croatia, Ukraine, Brazil, Russian Federation, Mexico, Romania, Slovakia
Annovis Bio Inc.

Terminated

Study of the Pharmacokinetics and Pharmacodynamics of POSIPHEN® in Subjects With Amnestic Mild Cognitive Impairment

Alzheimer's Disease | Amnestic Mild Cognitive Impairment

United States
Upstream Bio Inc.

Recruiting

A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALIANT)

Severe Asthma

United States, Canada
Upstream Bio Inc.

Recruiting

A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Participants With Chronic Rhinosinusitis With Nasal Polyps (VIBRANT)

Chronic Rhinosinusitis With Nasal Polyps

United States
Inmune Bio, Inc.

Recruiting

Study of INKmune in Patients With mCRPC (CaRe Prostate) (CaRe)

Cancer | Metastatic Castration-resistant Prostate Cancer | mCRPC

United States
Solarea Bio, Inc

Recruiting

SBD121, a Synbiotic Medical Food for RA Management

Rheumatoid Arthritis

Australia, New Zealand
Cellevolve Bio Inc

Not yet recruiting

A Phase 2 Study Evaluating JCPyV-specific T Cell Therapy for PML (ASCEND-JC)

Progressive Multifocal Leukoencephalopathy
Q32 Bio Inc.

Recruiting

Evaluating Safety and Efficacy of ADX-914 in Patients With Moderate to Severe Atopic Dermatitis (SIGNAL-AD)

Atopic Dermatitis

United States
Inmune Bio, Inc.

Recruiting

A Study of XPro1595 in Patients With Early Alzheimer's Disease With Biomarkers of Inflammation (MINDFuL)

Mental Disorders | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Neurocognitive Disorders | Neurodegenerative Diseases | Dementia | Alzheimer Disease | Tauopathies | Mild Cognitive Impairment

Australia, Canada, United Kingdom, Poland, Germany
ABL Bio, Inc.

Recruiting

This is a Study to Evaluate the Safety and Tolerability of ABL503, and to Determine the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D) of ABL503 in Subjects With Any Progressive Locally Advanced or Metastatic Solid Tumors

Advanced Solid Tumor

Korea, Republic of, United States
Adicet Bio, Inc

Recruiting

A Phase 1 Study of ADI-001 in B Cell Malignancies (GLEAN-1)

Lymphoma, Follicular | Lymphoma, Non-Hodgkin | Lymphoma, Mantle-Cell | Marginal Zone Lymphoma | Diffuse Large B Cell Lymphoma | Primary Mediastinal B-cell Lymphoma

United States
GID BIO, Inc.

Not yet recruiting

Adipose-derived SVF for Treatment of Erectile Dysfunction (ED)

Erectile Dysfunction

United States
Solarea Bio, Inc

Active, not recruiting

Food Trial Evaluating the Efficacy of SBD111 Versus Placebo for the Clinical Dietary Management of the Metabolic Processes of Osteopenia

Osteopenia

Australia
Gasherbrum Bio, Inc

Completed

Phase 1b/2a Study of GSBR-1290 in Adult Overweight or Obese Healthy Subjects and Subjects With Type 2 Diabetes Mellitus

Overweight or Obesity | Type2 Diabetes Mellitus

United States
Avenge Bio, Inc

Terminated

A Study of Intraperitoneally Administered AVB-001 in Patients With Serous Adenocarcinoma of the Ovary

Fallopian Tube Cancer | Primary Peritoneal Cavity Cancer | Primary Peritoneal Carcinoma | Neoplasm, Ovarian | Adenocarcinoma Ovary | Serous Adenocarcinoma of Ovary | Serous Adenocarcinoma of Primary Peritoneum | High Grade Serous Adenocarcinoma

United States

Clinical Trials Sponsored by Lotus Bio Inc.

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