Clinical Trials Sponsored by NHS Research Scotland

Total 684 results

University Hospital Southampton NHS Foundation...
Cancer Research UK; The Christie NHS Foundation Trust; Celldex Therapeutics; Oxford... and other collaborators

Active, not recruiting

A Combination of Rituximab and Varlilumab Immunotherapy in Patients With B-cell Lymphoma (RiVa)

B Cell Lymphoma

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Medical Research Council

Completed

Is Gait Speed and Sarcopenia Prognostic in Chronic Respiratory Disease?

Chronic Obstructive Pulmonary Disease and Allied Conditions

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Medical Research Council

Completed

Is the 4MGS a Useful Outcome Measure Post-PPCI

Acute Myocardial Infarction

United Kingdom
University of Edinburgh
NHS Lothian; Foundation for Skin Research

Unknown

An Assessment of Intra-lesional 3% Polidocanol Solution in the Treatment of Digital Myxoid Cyst

Ganglion Cysts

United Kingdom
Barts & The London NHS Trust
Cancer Research UK; Amgen

Unknown

Comparison Study of Standard Care Against Combination of Growth Factors Agents for Low-risk Myelodysplastic Syndromes (REGIME)

Myelodysplastic Syndrome

United Kingdom
NHS Greater Glasgow and Clyde
International Spinal Research Trust

Not yet recruiting

Spinal Stimulation for Chronic Complete Tetraplegia (Complete TESCS)

Spinal Cord Injuries
The Christie NHS Foundation Trust
AstraZeneca; Cancer Research UK

Terminated

Dual REctcal Angiogenesis or MEK Inhibition radioTHERAPY Trial (DREAMtherapy)

Rectal Cancer

United Kingdom
David Bearn
NHS Research and Development

Completed

0.018 or 0.022 Bracket Slot System More Effective in Orthodontic Treatment? (18v22)

Malocclusion

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Arthritis Research UK

Unknown

Acquired Immunodeficiency in ANCA Associated Vasculitis (ACQUIVAS)

Systemic Vasculitis
London Surgical Research Group
Royal Berkshire NHS Foundation Trust

Completed

Perioperative Reduction of Inapparent Myocardial Injury (PRIME)

Perioperative Myocardial Injury

United Kingdom
The Leeds Teaching Hospitals NHS Trust
Cancer Research UK

Recruiting

Experiences and Perceptions of Colonoscopy and New Technologies

Bowel Cancer | Colonoscopy

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Medical Research Council

Recruiting

Comparison of Optimal Hypertension Regimens (AIMHY-INFORM)

Hypertension

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Medical Research Council

Completed

Prolonged Enoxaparin in Primary Percutaneous Coronary Intervention (PENNYWISE)

Myocardial Infarction

United Kingdom
Moorfields Eye Hospital NHS Foundation Trust
Medical Research Council

Completed

Production of iPSC Derived RPE Cells for Transplantation in AMD

Age Related Macular Degeneration (AMD)
Royal Brompton & Harefield NHS Foundation Trust
Medical Research Council

Completed

Is the Short Physical Performance Battery a Useful Outcome Measure in Chronic Obstructive Pulmonary Disease

Lung Diseases | Disease Progression | Lung Diseases, Obstructive | Pulmonary Disease, Chronic Obstructive | Pulmonary Emphysema | Bronchitis, Chronic

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Cancer Research UK

Completed

A Feasibility Study for a Multicentre Randomised Controlled Trial to Compare Surgery With Needle Ablation Techniques in People With Small Renal Masses (4cm) (CONSERVE)

Renal Cancer

United Kingdom
The Leeds Teaching Hospitals NHS Trust
Cancer Research UK

Completed

Hepatitis C Rimantadine and Antiviral Combination Therapy (HepRiACT)

Hepatitis C

United Kingdom
The Christie NHS Foundation Trust
AstraZeneca; Cancer Research UK

Unknown

Radiotherapy & Olaparib in COmbination for Carcinoma of the Oesophagus (ROCOCO)

Carcinoma of the Oesophagus

United Kingdom
Barts & The London NHS Trust
King's College London; Cambridge University Hospitals NHS Foundation Trust; Medical... and other collaborators

Completed

Stromal TARgeting for PAncreatic Cancer (STAR_PAC) (STAR_PAC)

Pancreatic Adenocarcinoma

United Kingdom
UCLH/UCL Joint Research Office
Medical Research Council; Camden and Islington NHS Trust; Central and North West...

Recruiting

CBT and the Neural Circuits of Anxiety

Anxiety Disorders | Anxiety | Anxiety Depression | CBT | Anxiety Disorders and Symptoms | Anxiety Generalized | Generalised Anxiety Disorder | Anxiety Disorder; Mixed With Depression (Mild) | Anxiety Disorder Generalized

United Kingdom
University of Leeds
The Leeds Teaching Hospitals NHS Trust; Yorkshire Cancer Research; Airedale NHS... and other collaborators

Completed

Electronic Patient Self-Reported Outcomes to Improve Cancer Management and Patient Experiences (ePRIME)

Cancer

United Kingdom
University of Nottingham
Northern Care Alliance NHS Foundation Trust; Cambridge University Hospitals... and other collaborators

Recruiting

Pseudo-obstruction Assessment With MRI (POM)

Chronic Intestinal Pseudo-Obstruction

United Kingdom
Royal United Hospitals Bath NHS Foundation Trust
Janssen Research & Development, LLC; Sheffield Teaching Hospitals NHS Foundation... and other collaborators

Recruiting

ADOPT: Improving Diagnosis of Pulmonary Hypertension With AI and Echo (ADOPT)

Pulmonary Hypertension

United Kingdom
University Hospital Southampton NHS Foundation...
AstraZeneca; Cancer Research UK

Completed

Open Label Phase I/Randomised,Double Blind Phase II Study in mCRPC of AZD5363 In Combination With DP Chemotherapy (ProCAID)

Prostate Cancer

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
Medical Research Council

Recruiting

Hydroxychloroquine in ANCA Vasculitis Evaluation (HAVEN)

Microscopic Polyangiitis | Churg-Strauss Syndrome | ANCA Associated Vasculitis | Wegener Granulomatosis

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
AstraZeneca; Cancer Research UK

Recruiting

Platinum and Polyadenosine 5'Diphosphoribose Polymerisation Inhibitor for Neoadjuvant Treatment of Triple Negative Breast Cancer and/or Germline BRCA Positive Breast Cancer (PARTNER)

Breast Cancer

United Kingdom
Intensive Care National Audit & Research Centre
North Bristol NHS Trust

Unknown

Critical Illness Related Cardiac Arrest (CIRCA) (CIRCA)

Critical Illness

United Kingdom
London North West Healthcare NHS Trust
Medical Research Council CTU

Terminated

Ibuprofen and Opioid (Morphine or Diamorphine) for Acute Pain in Sickle Cell Disease - Sickle With Ibuprofen & Morphine (SWIM)

Sickle Cell Disease

United Kingdom
The Christie NHS Foundation Trust
Celgene Corporation; Leukemia Research Fund

Terminated

RESPeCT: Revlimid Early Stage Poor Prognosis Chronic Lymphocytic Leukaemia (CLL) Trial (RESPeCT)

Chronic Lymphocytic Leukaemia

United Kingdom
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust; Cambridge University Hospitals NHS Foundation...

Completed

Quantification of Breast RadioTherapy Associated Late Toxicity Using Novel UltraSound Techniques (QuaRTUS)

Breast Radiotherapy Toxicity

United Kingdom
South London and Maudsley NHS Foundation Trust
Carol Hardy, Research Lead, South London and Maudsley NHS Foundation

Completed

Social-emotional Under 4's Screening & Intervention S.U.S.I. (SUSI)

Child Development | Parent Child Relationships | Parent Child Interactions

United Kingdom
Liverpool University Hospitals NHS Foundation Trust
Kidney Research United Kingdom

Not yet recruiting

Expanding the Scope of Post-transplant HLA-specific Antibody Detection and Monitoring in Renal Transplant Recipients (HLA-AB)

Frailty | Kidney Transplant Rejection | Renal Transplant | Diagnosis | Kidney Transplant; Complications | Kidney Transplant | Renal Transplant Failure | Transplant Dysfunction

United Kingdom
Bio-Medical Research, Ltd.
Liverpool University Hospitals NHS Foundation Trust

Completed

Effects of Kneehab 12-week Peri-operative Total Knee Arthroplasty (KneehabTKA)

Knee Osteoarthritis | Disuse Atrophy

United Kingdom
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust; Cancer Research UK

Active, not recruiting

UK Genetic Prostate Cancer Study: Epidemiology and Molecular Genetics Studies (UKGPCS)

Prostate Cancer

United Kingdom
Royal Marsden NHS Foundation Trust
AstraZeneca; Cancer Research UK; RM/ICR Biomedical Research Centre

Active, not recruiting

Phase I Study to Assess Safety of AZD6738 Alone and in Combination With Radiotherapy in Patients With Solid Tumours (Patriot)

Solid Tumour Refractory to Conventional Treatment

United Kingdom
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust; Cancer Research UK

Completed

Preoperative Imaging in Retroperitoneal Sarcoma (PIRS)

Cancer

United Kingdom
Manchester University NHS Foundation Trust
Northern Care Alliance NHS Foundation Trust; National Institute for Health... and other collaborators

Completed

Comparing Gamification With Remote Monitoring Against Standard Rehabilitation, for Patients After Arthroscopic Subacromial Decompression Surgery (GAME)

Subacromial Impingement Syndrome | Shoulder Impingement Syndrome

United Kingdom
Papworth Hospital NHS Foundation Trust
King's College Hospital NHS Trust; The Leeds Teaching Hospitals NHS Trust; University... and other collaborators

Completed

Home Monitoring to Predict Exacerbation in Cystic Fibrosis (SmartCare)

Cystic Fibrosis

United Kingdom
University of Manchester
Northern Care Alliance NHS Foundation Trust; Royal Free Hospital NHS Foundation... and other collaborators

Enrolling by invitation

Early Diagnosis of SSc in the General Rheumatology Clinic - Pilot

Systemic Sclerosis | Raynaud Phenomenon

United Kingdom
University of Leeds
The Leeds Teaching Hospitals NHS Trust; Sheffield Teaching Hospitals NHS Foundation... and other collaborators

Completed

ePRIME: Patient-Reported AEs in Early Phase Trials

Cancer

United Kingdom
University of Oxford
King's College Hospital NHS Trust; Nottingham University Hospitals NHS Trust; Guy's and St Thomas' NHS Foundation Trust and other collaborators

Enrolling by invitation

Echocardiography: Value and Accuracy at REst and STress (EVAREST)

Coronary Artery Disease | Angina Pectoris | Ischaemic Heart Disease
Royal Devon and Exeter NHS Foundation Trust
National Institute for Health Research, United Kingdom; Portsmouth Hospitals...

Completed

NEWBIE Validate: Feasibility of a New Test to Measure Glucose in Newborn Blood Spots (NBS)

Neonatal Diabetes

United Kingdom
Gateshead Health NHS Foundation Trust
Newcastle-upon-Tyne Hospitals NHS Trust; National Institute for Health Research...

Unknown

Vascular Augmentation of Late-life Unremitted Depression (VALUeD) (VALUeD)

Depression

United Kingdom
University of Cambridge
The Leeds Teaching Hospitals NHS Trust; Cambridge University Hospitals NHS... and other collaborators

Active, not recruiting

Closed Loop From Onset in Type 1 Diabetes (CLOuD)

Diabetes Mellitus | Type 1 Diabetes

United Kingdom
University of Leeds
University College London Hospitals; The Leeds Teaching Hospitals NHS Trust; University... and other collaborators

Recruiting

A Platform Study of Novel Agents in Combination With Radiotherapy in NSCLC (CONCORDE)

Non Small Cell Lung Cancer

United Kingdom
Imperial College London
Royal Marsden NHS Foundation Trust; Chelsea and Westminster NHS Foundation... and other collaborators

Recruiting

COlorectal BReath Analysis (COBRA2)

Colorectal Cancer

United Kingdom
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust

Not yet recruiting

SBRT Alone or Followed by Niraparib for Oligometastases or Oligoprogression in Ovarian Cancer Following PARPi Therapy (SOPRANO)

Ovarian Cancer Recurrent

United Kingdom
Shruti Agrawal
Action Medical Research

Recruiting

Studying Trends of Auto-Regulation in Severe Head Injury in Paediatrics (STARSHIP)

TBI (Traumatic Brain Injury)

United Kingdom
Royal Marsden NHS Foundation Trust
Institute of Cancer Research, United Kingdom

Recruiting

Single Modality Trans Oral Robotic Surgery for Primary Oropharyngeal Cancer: Exploring the Impact of Surgical Margins on Local Disease Recurrence (STORM)

Head and Neck Squamous Cell Carcinoma

United Kingdom
Royal Marsden NHS Foundation Trust
Institute of Cancer Research, United Kingdom

Recruiting

A Trial Assessing Post-Operative Use of ProSpare, a Rectal Obturator in Prostate Cancer Radiotherapy (POPS)

Cancer

United Kingdom

Clinical Trials Sponsored by NHS Research Scotland

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