Clinical Trials Sponsored by Orphan Reach

Total 483 results

Kristian Reich, MD
LEO Pharma

Completed

Optimising Outpatient Care in Mild to Moderate Psoriasis (PSO-TOP) (PSO-TOP)

Mild to Moderate Psoriasis

United Kingdom, Germany, France, Spain, Netherlands, Sweden, Italy, Denmark
Manhattan Beach Orthodontics

Completed

Comparison of Standing Versus Supine 3D Cone Beam Computed Tomography in Patient With Obstructive Sleep Apnea (OSA)

Sleep Apnea | OSA

United States
Manhattan Beach Orthodontics

Not yet recruiting

Medicinal vs. Orthotic Comparison for Migraine Prevention: A Double-Blind Study

Migraine

United States
AOP Orphan Pharmaceuticals AG

Not yet recruiting

Investigational Trial to Evaluate Safety and Tolerability of Treprostinil in Children Diagnosed With PAH

Pulmonary Arterial Hypertension

Spain, Austria, France, Hungary
Amgen

Completed

Evaluating the Effect of Anakinra (r-metHuIL-1ra) on Vaccine AntibodyResponse in Subjects With Rheumatoid Arthritis (RA)

Rheumatoid Arthritis
AOP Orphan Pharmaceuticals AG

Completed

A Short Term Pharmacokinetic, Pharmacodynamic and Tolerability Study to Compare AOP200704 vs. Esmolol

Healthy Volunteers | Pharmacokinetics/Dynamics Study

Czech Republic
Amgen

Terminated

The SPECTRA Study

Rheumatoid Arthritis
Amgen

Completed

Juvenile Rheumatoid Arthritis

Juvenile Chronic Arthritis
OrphAI Therapeutics

Recruiting

A Phase 2a Study of LAM-001 for the Treatment of Pulmonary Hypertension

Pulmonary Hypertension

United States
OrphAI Therapeutics

Completed

A Study of LAM-003 in Patients With Acute Myeloid Leukemia

Acute Myeloid Leukemia | Oncology

United States
Swedish Orphan Biovitrum
Parexel

Completed

A Study to Investigate the Potential Influence of Nitisinone on the Metabolism and the Transport of Other Drugs in Healthy Volunteers

Drug Drug Interaction

Germany
Swedish Orphan Biovitrum
Amgen

Completed

Study to Evaluate Palifermin in the Reduction of Dysphagia in Patients With Locally Advanced Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer | Lung Cancer | Dysphagia
Swedish Orphan Biovitrum
Amgen

Completed

Palifermin for the Reduction of Oral Mucositis in Patients With Locally Advanced Head and Neck Cancer

Head and Neck Cancer | Mucositis | Stomatitis | Solid Tumors | Squamous Cell Carcinoma
Swedish Orphan Biovitrum
Amgen

Completed

Pharmacokinetic Study of Palifermin in Subjects Receiving Radiation Therapy and Chemotherapy Followed by Blood Stem Cell Support

Lymphoma | Leukemia | Myeloma
AOP Orphan Pharmaceuticals AG

Completed

A Pharmacokinetic, Pharmacodynamic, Safety Study With AOP LDLA202, ONO LDL50 and Esmolol in Healthy Volunteers

Healthy

Czech Republic
Amgen

Completed

Evaluating Kineret® (Anakinra) in Rheumatoid Arthritis (RA) Subjects Using aSelf-Reported Questionnaire

Rheumatoid Arthritis
Amgen

Completed

Evaluation of the Efficacy of Combination Treatment With Anakinra and Pegsunercept in Improving Rheumatoid Arthritis

Rheumatoid Arthritis
AOP Orphan Pharmaceuticals AG

Completed

Lancovutide (Moli1901) Inhalation Solution Study in Adolescents and Adults With Cystic Fibrosis

Cystic Fibrosis

Austria
AOP Orphan Pharmaceuticals AG

Completed

Safety Study of Pegylated Interferon Alpha 2b to Treat Polycythemia Vera (PEGINVERA)

Polycythemia Vera

Austria
Swedish Orphan Biovitrum
Amgen

Completed

A Study of Palifermin for the Reduction of Oral Mucositis in Patients With Locally Advanced Head and Neck Cancer Receiving Postoperative Radiotherapy and Concurrent Chemotherapy

Head and Neck Cancer | Mucositis
AOP Orphan Pharmaceuticals AG

Completed

Anagrelide Retard vs. Placebo: Efficacy and Safety in "At-risk" Patients With Essential Thrombocythaemia (ARETA)

Essential Thrombocythaemia

Poland, Slovakia, Bulgaria, Russian Federation, Romania, Croatia, Lithuania, Austria, Ukraine
AOP Orphan Pharmaceuticals AG

Completed

Anagrelide Retard in Essential Thrombocythemia (TEAM-ET)

Essential Thrombocythemia

Austria, Bulgaria, Lithuania, Poland, Russian Federation
AOP Orphan Pharmaceuticals AG

Completed

Long-term PK and Safety/Tolerability Testing LDLL600 Against Esmolol in Healthy Volunteers

Healthy

Czech Republic
Swedish Orphan Biovitrum
Amgen

Completed

Palifermin for the Reduction of Oral Mucositis in Single-dose Evaluation (PROMISE)

Lymphoma | Leukemia | Cancer
Swedish Orphan Biovitrum
Amgen

Completed

Trial to Evaluate Palifermin in the Reduction of Acute Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Allogeneic Marrow/Peripheral Blood Progenitor Cell (PBPC) Transplantation

Hematologic Malignancies | Graft Versus Host Disease
AOP Orphan Pharmaceuticals AG

Completed

Anagrelide vs. Hydroxyurea - Efficacy and Tolerability Study in Patients With Essential Thrombocythaemia (ANAHYDRET)

Essential Thrombocythaemia

Austria, Czech Republic, France, Germany, Hungary, Italy, Lithuania, Poland, Singapore, Slovenia
Swedish Orphan Biovitrum
Amgen

Withdrawn

A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Locally Advanced Head and Neck Cancer Receiving Postoperative Radiotherapy

Head and Neck Cancer
Rush University Medical Center
Cures Within Reach

Completed

Efficacy of Evidence-Based PTSD Treatment Via Prebiotic Supplementation

Post Traumatic Stress Disorder

United States
Orpha Labs

Unknown

Study of ORL-1M (D-mannose) in Patients With CDG-Ib

CDG Ib

Turkey
Orpha Labs

Unknown

Study of ORL-1G (D-galactose) in Patients With Glycogen Storage Disease Type 14

Glycogen Storage Disease, Type 14

Turkey
Orpha Labs

Completed

Study of ORL-1B in Patients With Biotinidase Deficiency

Biotinidase Deficiency
Swedish Orphan Biovitrum
Cerner Enviza

Completed

Impact on French Physician's Haemophilia Treatment Management Decision Based on Systematic Joint Examination (A-MOVE)

Hemophilia A

France
Swedish Orphan Biovitrum
Cerner Enviza

Completed

rFVIIIFc (Elocta®) ITI Chart Review in Patients With Haemophilia A

Hemophilia A With Inhibitor

France, Ireland, Italy, Norway, Germany, Kuwait, Saudi Arabia, Switzerland
Orpha Labs

Completed

Study of ORL-1F (L-fucose) in Patients With Leukocyte Adhesion Deficiency Type II

Leukocyte Adhesion Deficiency, Type II
Northwell Health
Swedish Orphan Biovitrum

Recruiting

Effects of Anakinra in Subjects With Corticosteroid-resistant/Intolerant Meniere's Disease and Autoimmune Inner Ear Disease

Meniere's Disease | Autoimmune Inner Ear Disease

United States
Swedish Orphan Biovitrum
Syneos Health

Active, not recruiting

A Study Evaluating Physical Activity and Joint Health in Severe Haemophilia A Patients ≥12 Years Treated Once Weekly With Efanesoctocog Alfa (FREEDOM)

Hemophilia A, Severe

Germany, Spain, France, Czechia, Netherlands, Ireland, Austria, Croatia, Greece, Italy, Norway, Slovenia, Sweden, United Kingdom
Orphan Medical
Johns Hopkins University

Completed

Physiological, Behavioral and Subjective Effects of Drugs (GHB)

Sedative Abuse

United States
University of Illinois at Chicago
Cures Within Reach

Recruiting

Transnasal Esophagoscopy (TNE) Esophageal Cancer Screening

Esophageal Cancer

United States
University of Illinois at Chicago
Cures Within Reach

Not yet recruiting

Topical Probiotic Sinus Irrigations for Treating Chronic Sinusitis

Chronic Rhinosinusitis (Diagnosis)
Swedish Orphan Biovitrum
Cerner Enviza

Active, not recruiting

An International Study to Evaluate the Real-world Effectiveness and Usage of Alprolix in Patients With Haemophilia B (B-MORE)

Hemophilia B

Czechia, Greece, Ireland, Italy, Norway, Saudi Arabia, Spain, Sweden, United Kingdom
Swedish Orphan Biovitrum
Cerner Enviza

Completed

A Study to Evaluate the Real-world Effectiveness and Usage of Alprolix in Patients With Haemophilia B in France (B-SURE)

Haemophilia B

France
Swedish Orphan Biovitrum
ICON plc

Completed

Prospective, Non-interventional Study to Evaluate the Effectiveness of Elocta Compared to Conventional Factor Products

Hemophilia A

France, Italy, Norway, Sweden, United Kingdom, Austria, Belgium, Finland, Spain
California State University, Long Beach

Completed

Active Moms Project: Physical Activity Intervention for Low-Income Mothers

Physical Inactivity
Prof. Kristian Reich

Completed

Trial in Patients With Psoriasis Treated With Methotrexate Using an Optimized Treatment Schedule (METOP) (METOP)

Psoriasis Vulgaris

Germany
California State University, Long Beach

Completed

An mHealth Exercise Intervention for Sedentary Adults

Exercise Behavior

United States
VA Long Beach Healthcare System

Completed

Comparing TR Band to Statseal in Conjunction With TR Band

Cardiovascular Diseases | Coronary Artery Disease | Atherosclerosis | Angina Pectoris | Arterial Occlusion | Hematoma | Anticoagulant-Induced Bleeding

United States
VA Long Beach Healthcare System

Completed

Comparing TR Band to Statseal in Conjunction With TR Band II (Statseal II)

Cardiovascular Diseases | Coronary Artery Disease | Atherosclerosis | Arterial Occlusion | Hematoma | Anticoagulant-induced Bleeding

United States
Kristian Reich

Completed

Apremilast in Patients With Moderate to Severe Palmoplantar Pustulosis (PPP) (APLANTUS) (APLANTUS)

Palmoplantar Pustulosis

Germany
Swedish Orphan Biovitrum
Apellis Pharmaceuticals, Inc.

Recruiting

Evaluate the PK Efficacy Safety and Tolerability of Pegcetacoplan in Patients With Thrombotic Microangiopathy

Transplant-Associated Thrombotic Microangiopathy

United States, France, Greece, Italy, Spain
University Hospital, Bonn
Swedish Orphan Biovitrum

Recruiting

Sonography and Haemophilia

Haemophilia | Sonography

Germany

Clinical Trials Sponsored by Orphan Reach

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