Clinical Trials Sponsored by Royal Brompton and Harefield NHS Foundation Trust

Total 406 results

Royal Brompton & Harefield NHS Foundation Trust

Recruiting

Studying the Airway Microenvironment in Patients Undergoing Surgical and Bronchoscopic Interventions for COPD (COPD-ENVIRON)

Chronic Obstructive Pulmonary Disease | Emphysema | Chronic Bronchitis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Completed

CMR to Assess Fibrosis in Cardiomyopathy Using Eplerenone

Cardiomyopathy

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Does Extra-Corporeal Membrane Oxygenation Alter Antiinfectives Therapy Pharmacokinetics in Critically Ill Patients (EAT-PK)

Critical Illness | Infection | Extracorporeal Membrane Oxygenation Complication

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

EBUS-TBNA vs Acquire TBNB

Mediastinal Lymphadenopathy

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Evaluation of Speckle Tracking Parameters as Predictors of Successful VA SPECKLE ECMO (SPECKLE-ECMO)

Cardiogenic Shock

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Completed

Does Cardiac REhabilitation Improve Functional, Independence, Frailty and Emotional outCOmes Following Trans Catheter Aortic ValvE Replacement? (RECOVER-TAVR)

Aortic Stenosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Terminated

Sequestration of Platelets Prior to Bypass Reduces Bleeding After Cardiac Surgery

Blood Coagulation Disorders | Blood Platelet Disorders | Cardiopulmonary Bypass | Cardiac Surgical Procedures

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Left Atrial Appendage Electrical Isolation and Occlusion to Treat Persistent Atrial Fibrillation: A Safety and Feasibility Study (LEIO-AF)

Persistent Atrial Fibrillation

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Withdrawn

Dysfunctional Breathing in Difficult Asthma.

Asthma

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Fibre Specific Signalling in the Locomotor Myopathy of Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Catheter Versus Thoracoscopic Surgical Ablation Strategy in Persistent Atrial Fibrillation (CASA-AF)

Persistent Atrial Fibrillation

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Early Percutaneous Coronary Intervention (PCI) After Fibrinolysis Versus Standard Therapy in ST Segment Elevation Myocardial Infarction (STEMI) Patients

Myocardial Infarction

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Completed

Should Any One Airway Clearance Technique be Recommended for People With Cystic Fibrosis? (ACT)

Cystic Fibrosis
Royal Brompton & Harefield NHS Foundation Trust

Completed

Do Musculoskeletal Techniques Improve Forced Expiratory Volume in One Second in Adults With Cystic Fibrosis?

Cystic Fibrosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Completed

The Diagnosis of Oral Allergy Syndrome Through the Use of a Structured Questionnaire

Food Allergy

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Completed

Airway Clearance Using High Frequency Chest Wall Oscillation

Cystic Fibrosis

United Kingdom
Royal Marsden NHS Foundation Trust
Royal Brompton and Harefield NHS Foundation Trust

Unknown

A Prospective Longitudinal Cohort Study Looking at the Difference in Carotid Intima-medial Thickness Between Irradiated and Unirradiated Carotid Arteries in Patients With Head and Neck Cancer

Head and Neck Tumours

United Kingdom
Royal Marsden NHS Foundation Trust
Royal Brompton and Harefield NHS Foundation Trust

Completed

A Cross-sectional Study Looking at the Effect of Radiotherapy on Carotid Intima-medial Thickness in Head and Neck Cancer

Head and Neck Tumours
Royal Brompton & Harefield NHS Foundation Trust
GlaxoSmithKline

Completed

IPF Drug Deposition Study (TOPICAL-IPF)

Idiopathic Pulmonary Fibrosis

United Kingdom
ResMed
Royal Brompton & Harefield NHS Foundation Trust

Completed

AutoVPAP Versus VPAP; Assessment of Sleep and Ventilation

Neuromuscular Disease | Chest Wall Disorder

United Kingdom
ResMed
Royal Brompton & Harefield NHS Foundation Trust

Completed

Autotitrating Versus Standard Non-invasive Ventilation (NIV) in Newly Diagnosed Patients

Neuromuscular Disease | Chest Wall Disorder | Nocturnal Hypoventilation

United Kingdom
ResMed
Royal Brompton & Harefield NHS Foundation Trust

Withdrawn

Autotitrating Versus Standard Non-invasive Ventilation (NIV) in Acute Exacerbation of Respiratory Failure

Chronic Obstructive Pulmonary Disease | Respiratory Failure | Obesity Hypoventilation Syndrome | Neuromuscular Disease | Chest Wall Disorder

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Actelion

Unknown

Bosentan in Pulmonary Hypertension in Interstitial Lung Disease Treatment Study (B-PHIT)

Idiopathic Pulmonary Fibrosis | Pulmonary Hypertension | Interstitial Lung Disease | Nonspecific Interstitial Pneumonia

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
NHS Highlands

Completed

The Sunrise OSA Trial (SOSAT)

Obstructive Sleep Apnea

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Aalborg University

Completed

Metabolic Cost of IMT

Mechanical Ventilation Complication

United Kingdom
Oxehealth Limited
Royal Brompton & Harefield NHS Foundation Trust

Completed

Analysis of Vital Signs in Patients With COVID-19

Respiratory Disease

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Acutus Medical

Unknown

HCM-AF Ablation With ACUTUS

Atrial Fibrillation | Hypertrophic Cardiomyopathy
Heartfelt Technologies
Royal Brompton & Harefield NHS Foundation Trust

Completed

Feasibility Study of a New Peripheral Oedema Monitor for Heart Failure

Heart Failure, Diastolic | Edema Brain | Decompensated Heartfailure

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Ben Williams Trust

Unknown

Families' Experiences of Paediatric ICC Diagnosis (FEPICCD)

Inherited Cardiac Conditions
Bispebjerg Hospital
Royal Brompton & Harefield NHS Foundation Trust

Recruiting

A Comprehensive Evaluation of the Impact of ATP on Laryngeal Symptoms, Hypersensitivity and Function (MISP COUGH)

Chronic Refractory Cough

Denmark
Royal Brompton & Harefield NHS Foundation Trust
Olympus Corporation

Completed

EBUS-TBNA vs Flex 19G EBUS-TBNA

Lymphoma | Lung Cancer | Lymphadenopathy | Sarcoidosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
British Heart Foundation

Completed

Programme to Optimise Risk Factors in Patients Waiting for Coronary Artery Bypass Surgery

Coronary Artery Disease

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
Royal Brompton & Harefield NHS Foundation Trust

Unknown

FIBRotic Interstitial Lung Disease and Nocturnal OXygen (FIBRINOX)

Obstructive Sleep Apnea | Idiopathic Pulmonary Fibrosis | Sleep Disturbance | Sleep Hypoventilation

United Kingdom
East and North Hertfordshire NHS Trust
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Assessment of Thrombotic Status in Patients With Atrial Fibrillation

Atrial Fibrillation
Guy's and St Thomas' NHS Foundation Trust
Royal Brompton & Harefield NHS Foundation Trust

Recruiting

Optimisation of Mechanical Insufflation:Exsufflation (MIE2)

Neuromuscular Diseases

United Kingdom
East and North Hertfordshire NHS Trust
Royal Brompton & Harefield NHS Foundation Trust

Not yet recruiting

Avr Thrombosis OutcoMe Study (ATOM)

Aortic Stenosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Medical Research Council

Completed

Is Gait Speed and Sarcopenia Prognostic in Chronic Respiratory Disease?

Chronic Obstructive Pulmonary Disease and Allied Conditions

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Medical Research Council

Completed

Is the 4MGS a Useful Outcome Measure Post-PPCI

Acute Myocardial Infarction

United Kingdom
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust

Completed

Exacerbations in Severe Asthma Patients: Mechanisms and Biomarkers

Asthma

United Kingdom
University of Cincinnati
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Pirfenidone for Progressive Fibrotic Sarcoidosis (PirFS)

Sarcoidosis, Pulmonary

United States
Royal Brompton & Harefield NHS Foundation Trust
Burdett Trust for Nursing

Terminated

SPOT-FRAILTY Assessment of Frailty in Patients Over the Age of 70 Undergoing a Cardiac Intervention (SPOT FRAILTY)

Frailty

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
GlaxoSmithKline; Cystic Fibrosis Trust

Completed

Cystic Fibrosis Withdrawal of Inhaled Steroids Evaluation Study (CF WISE Study)

Cystic Fibrosis

United Kingdom
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust

Not yet recruiting

Therapy to Maintain Remission in Dilated Cardiomyopathy (TRED-HF2)

Heart Diseases | Heart Failure | Cardiomyopathies | Cardiomyopathy, Dilated
Royal Brompton & Harefield NHS Foundation Trust
University of Oxford

Completed

Mindfulness in Chest Pain - a Feasibility Randomized Controlled Study (MIPIC)

Chest Pain

United Kingdom
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust

Completed

Heart Function in Patients Assessed for Sleep Apnoea

Heart Failure | Obstructive Sleep Apnea | Sleep Disordered Breathing | Heart Failure With Preserved Ejection Fraction | Heart Failure With Normal Ejection Fraction | Central Sleep Apnea

United Kingdom
Cell Therapy Ltd.
Royal Brompton & Harefield NHS Foundation Trust

Unknown

A Trial of Cardiac Injections of iMP Cells During CABG Surgery

Myocardial Fibrosis
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust

Completed

Prednisolone Pharmacokinetics in Severe Asthma

Asthma

United Kingdom
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust

Completed

Haemostatic Markers in Cardiopulmonary Bypass

Cardiopulmonary Bypass Surgery | Unfractionated Heparin

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Imperial College London

Unknown

Lung Volume Reduction Coil Microbiome Study (LVRC-Micro)

Chronic Obstructive Pulmonary Disease | Emphysema

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
AHEPA University Hospital

Completed

a-Klotho in Relation to Calcification in the Coronary Arteries and Aortic Valve in Patients With Chronic Kidney Disease

Chronic Kidney Diseases | Vascular Calcification

Clinical Trials Sponsored by Royal Brompton and Harefield NHS Foundation Trust

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