Clinical Trials Sponsored by WCG IRB

Total 146 results

Running Injury Clinic
Alberta Health services; WCB Alberta

Unknown

An Efficacy Study of Exercise Rehabilitation on Pain and Disability for Patients With Non-specific Low Back Pain (LBP-RCT)

Low Back Pain, Mechanical

Canada
IRB of NTUH Hsin-Chu Branch

Completed

Needlescopic-assisted Uniportal vs Uniportal VATS (UNeed)

Lung Cancer | Lung Cancer Metastatic | Mediastinal Tumor | Nodule Solitary Pulmonary | Bullous Disease Lung

Taiwan
TRB Chemedica International SA
ArthroLab Inc.

Completed

Effect of Diacerein vs Celecoxib on Symptoms and Structural Changes in Symptomatic Knee Osteoarthritis (DISSCO)

Osteoarthritis | Osteoarthritis, Knee

Czechia, Austria, Belgium, Canada, Spain
Markus Mapara
ITB-Med LLC

Recruiting

Siplizumab for Sickle Cell Disease Transplant (CD2 SCD)

Anemia, Sickle Cell

United States
Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator...
PPD

Active, not recruiting

Proof-of-Concept Clinical Pharmacology Trial for COVID-19 Antigen Presentation Therapeutic Biologics (COV19-APTP-B)

Covid19

United States
IR Technology, LLC

Completed

Comparing the Efficacy of a Dual-Frequency LLLT Device With a Sham Device as a Therapy for Adipose Tissue Loss

Obesity | Body Weight | Cellulite | Fat Burn | Abdominal Fat | Adipose Tissue Atrophy

United States
King's College London
NHS Devon ICB

Completed

Midwifery Retention Project

Retention/Attrition of Midwives

United Kingdom
Thomas Erb

Completed

Laryngeal Reflex Study Under Propofol Anesthesia: Effect of Intravenous Lidocaine (LR6)

Laryngospasm

Switzerland
Thomas Erb

Completed

Remifentanil and Laryngeal Reflex Responses in Pediatric Patients With URI

Upper Respiratory Infections

Switzerland
Schulthess Klinik
Winterthur Institute of Health Economics (WIG), Switzerland

Completed

Costs and Consequences of Three Common Orthopedic Procedures on the Upper Extremity

Rotator Cuff Tear | Rotator Cuff Tear Arthropathy | Trapeziometacarpal Osteoarthritis | Degenerative Arthritis of Left Glenohumeral Joint | Degenerative Arthritis of Right Glenohumeral Joint

Switzerland
CG Pharmaceuticals, Inc

Recruiting

A Study of Ivaltinostat Plus Capecitabine or Capecitabine in Metastatic Pancreatic Adenocarcinoma

Metastatic Pancreatic Adenocarcinoma

United States
CG Oncology, Inc.

Recruiting

Study of Cretostimogene Given in Patients With Non-Muscle Invasive Bladder Cancer ,Unresponsive to Bacillus-Calmette-Guerin (BOND-003)

Non Muscle Invasive Bladder Cancer | High-grade Ta/ T1 Papillary Disease Bladder Cancer

United States, Korea, Republic of, Taiwan, Japan, Australia
CG Oncology, Inc.

Available

An Expanded Access Program of Cretostimogene Grenadenorepvec for Treatment of NMIBC for Patients Unresponsive to BCG

Bladder Cancer | Urothelial Carcinoma | Urologic Cancer | Non-Muscle Invasive Bladder Cancer
CG Oncology, Inc.

Completed

Safety and Efficacy of CG0070 Oncolytic Virus Regimen for High Grade NMIBC After BCG Failure (BOND2)

Bladder Cancer

United States
Ira Winer

Recruiting

ASk Questions in GYnecologic Oncology (ASQ-GYO) (ASQ-GYO)

Cervical Cancer | Ovarian Cancer | Vulvar Cancer | Endometrial Cancer | Vaginal Cancer | Gestational Trophoblastic Disease

United States
Elizabeth C. Verna
ITB-Med LLC

Not yet recruiting

SIPLIZUMAB in AILD and LT (SET-SAIL)

Autoimmune Liver Disease | Primary Sclerosing Cholangitis | Autoimmune Hepatitis | Cirrhosis, Liver | Liver Transplant Disorder | End Stage Liver DIsease

United States
IR Technology, LLC

Not yet recruiting

Clinical Trial of the invisaRED® IR REHAB Device When Used as an Adjunctive Therapy for Nociceptive Musculoskeletal Pain

Musculoskeletal Pain | Nociceptive Pain
Ira Winer

Recruiting

ONC201 Plus Weekly Paclitaxel in Patients With Platinum Refractory or Resistant Ovarian Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Platinum-Resistant Fallopian Tube Carcinoma | Platinum-Resistant Primary Peritoneal Carcinoma | Malignant Ovarian Epithelial Tumor | Platinum-Resistant Ovarian Carcinoma | Refractory Ovarian... and other conditions

United States
IR Scientific Inc.

Completed

Efficacy of Sensi-IP Toothpaste in the Treatment of Dentinal Hypersensitivity Compared to a Sodium Fluoride Toothpaste

Dentinal Hypersensitivity

United States
Institute of Bioengineering and Bioimaging (IBB)
Massachusetts General Hospital

Recruiting

Remote Monitoring of High-Risk Patients With Chronic Cardiopulmonary Diseases

Chronic Obstructive Pulmonary Disease | Asthma | Cystic Fibrosis | Congestive Heart Failure

United States
University of Sao Paulo General Hospital
TRB Chemedica

Completed

Project Arthritis Recovering Quality of Life by Means Education II (PARQVE II)

Osteoarthritis | Knee Osteoarthritis

Brazil
University of Alabama at Birmingham
ITB-Med LLC

Not yet recruiting

A Study to Demonstrate the Safety and Efficacy of Siplizumab in the Treatment of Hidradenitis Suppurativa

Hidradenitis Suppurativa
Institute of Bioengineering and Bioimaging (IBB)
National Skin Centre, Singapore

Recruiting

Non-invasive Photoacoustic Imaging of Skin Inflammatory Disorders With Machine Learning-assisted Scoring

Psoriasis | Eczema

Singapore
Massachusetts General Hospital
Ossium Health, Inc.; ITB-Med LLC

Recruiting

Delayed Tolerance Through Mixed Chimerism

Kidney Failure | Kidney Transplant; Complications | Chimera

United States
Wrightington, Wigan and Leigh NHS Foundation Trust
TRB Chemedica

Recruiting

Comparing Injection Treatments for Tennis Elbow (CITTE)

Lateral Epicondylitis | Tennis Elbow | Elbows Tendonitis

United Kingdom
Mark Vander Weg
VA Office of Research and Development

Unknown

Dissemination of a Tailored Tobacco Quitline for Rural Veteran Smokers

Tobacco Use | Nicotine Dependence

United States
Cybin IRL Limited
Worldwide Clinical Trials; Drug Safety Navigator

Not yet recruiting

A Study of a N, N-dimethyltryptamine (DMT) Analog (CYB004) in Participants With Generalized Anxiety Disorder (GAD) With Depressive Symptoms

Generalized Anxiety Disorder

United States
MVG Industries SAS
HRB Clinical Research Facility, Galway (CRFG)

Completed

Pilot Clinical Study on a Low-power Electromagnetic Wave Breast Imaging Device for Cancer Screening Purposes.

Breast Cancer | Breast Cyst

Ireland
Galmed Pharmaceuticals Ltd
Kramer Consulting, LLC; WCCT Global; Diamond Pharma Services Regulatory Affairs... and other collaborators

Completed

Pharmacokinetics of Single and Multiple Escalating Doses of Aramchol Administered Under Fed Conditions in Healthy Chinese Volunteers

Healthy Volunteers

United States
Clinical Nutrition Research Centre, Singapore
Institute of Bioengineering and Bioimaging (IBB)

Completed

Brown Adipose Tissue Activation and Energy Expenditure by Capsinoids Stimulation With Trimodality Imaging Using 18-FDG-PET, Fat Fraction MRI and Infrared Thermography (TACTICAL-II)

Brown Adipose Tissue

Singapore
Wake Forest University Health Sciences
W.G. "Bill" Hefner Salisbury VA Medical Center

Not yet recruiting

Healthy Living Partnerships for Veterans With Migraine (HELP-VM)

Migraine | Migraine Disorders | Migraine Without Aura | Migraine With Aura
Mark Vander Weg
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Preventing Weight Gain and Controlling Blood Pressure During Smoking Cessation in Hypertensive Smokers

Heart Diseases | Cardiovascular Diseases | Hypertension

United States
Montefiore Medical Center
Medanta Institute Delhi; AIIMS Patna; HCG Oncology Bangalore; NSCB Jabalpur

Completed

Mucormycosis in COVID-19 (MUNCO)

Covid19 | Aspergillosis | Mucormycosis | Candida Infection

United States
Ib Abildgaard Jacobsen

Completed

The Effect of Spironolactone on Blood Pressure in Type-2 Diabetics With Resistant Hypertension (SDHDS)

Diabetes Mellitus | Arterial Hypertension | Hypertension, Resistant to Conventional Therapy
Ib Abildgaard Jacobsen

Completed

Amiloride for Resistant Hypertension

Hypertension | Type 2 Diabetes Mellitus | Microalbuminuria

Denmark
CG Oncology, Inc.
Merck Sharp & Dohme LLC

Active, not recruiting

Study of CG0070 Given in Combination With Pembrolizumab, in Non-Muscle Invasive Bladder Cancer, Unresponsive to Bacillus Calmette-Guerin (CORE-001)

Non Muscle Invasive Bladder Cancer

United States, Korea, Republic of
Cybin IRL Limited
Clinilabs Drug Development Corporation; Drug Safety Navigator

Completed

A Study of a Psilocybin Analog (CYB003) in Healthy Participants With and Without Major Depressive Disorder

Major Depressive Disorder

United States
Alar Irs
Tartu University Hospital; North Estonia Regional Hospital

Unknown

Proactive Cardiovascular Prevention Strategy in Subjects With High Genetic Risk (EstPerMedCV)

Cardiovascular Diseases | Primary Prevention

Estonia
Theranexus
Institut de recherche biomédicale des armées (IRBA), Bretigny sur Orge, France

Completed

Impact of THN102 on Attention, Wakefulness and Cognitive Performance During Total Sleep Deprivation

Sleep Deprivation
Hospital Universitario Araba
Instituto de Salud Carlos III; Ibermática/i3B; Bioraba

Completed

Sleep Thermography for Diagnosis of Obstructive Sleep Apnea (TERMOAPNEA) (TERMOAPNEA)

Obstructive Sleep Apnea (OSA)

Spain
London South Bank University
NHS Lambeth; NHS Southwark CCG; Allen Carr Easyway

Completed

Study Comparing Two Stop Smoking Intervention Efficacies

Smoking Cessation

United Kingdom
ANRS, Emerging Infectious Diseases
Programme PAC-CI; Centre Population et Développement (CEPED/IRD)

Recruiting

Feasibility and Effectiveness of a Pilot Program of Physical Activity to Improve HIV Related Functional Limitations and Disability in Adults Aged 40 and Older From Côte d'Ivoire (VIRAGE+)

HIV Infections

Côte D'Ivoire
Bournemouth University
Institute of Bioengineering and Bioimaging (IBB); University of Portsmouth; Loughborough...

Completed

The Effect of Nitrate on Brown Fat

Diabetes Mellitus, Type 2

United Kingdom
Queen Mary University of London
Hoffmann-La Roche; MedSIR; Westdeutsche Studiengruppe GmbH (WSG)

Active, not recruiting

Investigate the Contribution of Ipatasertib to Neoadjuvant Chemotherapy Plus Atezolizumab in TNBC (BARBICAN)

Triple Negative Breast Cancer

United Kingdom
Institute of Tropical Medicine, Belgium
Institut National pour la Recherche Biomedicale (INRB)

Not yet recruiting

Safety and Immunogenicity of Ervebo® and Zabdeno® Booster Vaccines Against Ebola Virus Following Previous Vaccination With the Zabdeno/Mvabea® or Ervebo® Vaccine Schedules in DRC (EBO-BOOST)

Ebola Virus Disease

Congo, The Democratic Republic of the
Mark Vander Weg
Iowa City VA Health Care System

Unknown

Treating Smokeless Tobacco Use in Rural Veterans

Nicotine Dependence | Smokeless Tobacco

United States
Assistance Publique - Hôpitaux de Paris
UMMISCO - Institute of Research for Development (IRD); CoreLab Banook

Recruiting

Development of an Artificial Intelligence Algorithm to Detect Pathological Repolarization Disorders on the ECG and the Risk of Ventricular Arrhythmias (DEEPECG4U)

Ventricular Arrythmia | Cardiac Disease

France
University of Zurich
Foundation Wings For Life; IRP International Foundation for Research in Paraplegia

Completed

Upper Limb Activity in Human SCI Rehabilitation

Spinal Cord Injury

Switzerland
University of Udine
National Research Council (CNR), Institute of Biomolecular Chemistry (ICB)...

Recruiting

Endocannabinoid Activity Remodulation for Psychosis Liability in Youth (EARLY)

Clinical High Risk for Psychosis | Ultra High Risk for Psychosis | Attenuated Psychotic Symptoms

Italy
University Hospital, Grenoble
Commissariat A L'energie Atomique; Institute for Advanced Biosciences (IAB)...

Not yet recruiting

Prospective Evaluation of ENDOSWIR Device Versus Pathology for Squamous Cell Carcinoma of Upper Aerodigestive Tract (ENDOSWIR-VADS) (ENDOSWIR-VADS)

Head and Neck Neoplasms

Clinical Trials Sponsored by WCG IRB

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CROs in Italy

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