Search clinical trials for: Anti-epileptic drug (AED)

Total 261344 results

Cerevel Therapeutics, LLC

Active, not recruiting

An Open-label Extension Trial of CVL-865 as Adjunctive Therapy in the Treatment of Focal Onset Seizures

Seizures

United States, Spain, Australia, Poland, Ukraine, Serbia
RadianQbio

Completed

AED Log Analysis of 19 Cases in Out-of-hospital Environment

Cardiac Arrest, Sudden

Korea, Republic of
The University of Hong Kong
Queen Mary Hospital, Hong Kong

Completed

Alcohol Brief Intervention Plus Personalized Mobile Chat-based Intervention to Reduce Alcohol Misuse in an Emergency Department

Alcohol Use Disorder

Hong Kong
UCB BIOSCIENCES, Inc.

Completed

Determine Safety and Efficacy of Long-term Oral Lacosamide in Patients With Partial Seizures

Partial Epilepsies

United States
The Hong Kong Polytechnic University
Tung Wah College; Hospital Authority, Hong Kong

Recruiting

E-health Enhanced Motor-cognitive Training for AED Discharged Older Adults With Cognitive Frailty

Frailty | Mild Cognitive Impairment

Hong Kong
UCB Biopharma S.P.R.L.
Parexel

Completed

A Clinical Study to Investigate the Long-term Use of Lacosamide as Monotherapy in Subjects Who Completed Study SP0994

Epilepsy

Bulgaria, Finland, France, Germany, Japan, Korea, Republic of, Latvia, Mexico, Philippines, Poland, Romania, Russian Federation, Sweden, Switzerland, Ukraine
Copenhagen Academy for Medical Education and Simulation
University of Southern Denmark; TrygFonden, Denmark; Emergency Medical Services...

Completed

The Effect of T-CPR on the Quality of CPR and AED Use

Cardiopulmonary Resuscitation | Basic Cardiac Life Support

Denmark
Chang Gung Memorial Hospital

Recruiting

iGOGO -Assessment of CPR Skill,Willingness and Public AED in Layperson:A Cohort Study

Out-Of-Hospital Cardiac Arrest

Taiwan
Oslo University Hospital

Unknown

Ketogenic Diet vs.Antiepileptic Drug Treatment in Drug Resistant Epilepsy

Epilepsy | Mental Retardation

Norway
Emory University
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Developmental Effects On Children Of Women Who Take Antiepileptic Drugs During Pregnancy

Epilepsy | Cognition Disorders | Seizure

United States, United Kingdom
Eindhoven University of Technology
Clinical Trial Center Maastricht B.V.

Recruiting

Priming the Epileptic Brain: tVNS to Improve Efficacy of add-on AED in Patients With Focal Epilepsy (PREP)

Focal Epilepsy

Netherlands
Eisai Inc.

Completed

A Post-marketing Observational Study Of The Use Of Zonisamide (ZNS) in the Adjunctive Treatment Of Adult Patients With Partial Onset Seizures (Study E2090-E044-410) (ZOOM)

Partial Onset Seizures

Germany, Sweden, Norway, Austria, Denmark
Novartis

Completed

Efficacy and Safety of BGG492 as Adjunctive Treatment in Patients With Partial Onset Seizures

Partial Onset Seizures

United States, Italy, Germany, Taiwan, Hungary, Switzerland, Bulgaria, Korea, Republic of, Slovakia, Poland
International Food Policy Research Institute

Completed

Impact of Behavior Change Communications and Market-based Approach to Delivering Micronutrient Powders on Stunting, Infant Feeding Practices and Anemia in Bangladesh

Breastfeeding | Complementary Feeding | Child Malnutrition | Childhood Anemia

Bangladesh
Neurocrine Biosciences

Completed

A Study to Investigate How Effective, Safe and Tolerable the Drug NBI-921352 is When Used With Anti-seizure Medications in Adults With Focal Onset Seizures

Focal Onset Seizure | Focal Onset Epilepsy

Spain, Belgium, Czechia, France, Italy, Australia, Hungary, United Kingdom
Novartis Pharmaceuticals

Completed

Phase II BGG492 Capsule Extension for Partial Epilepsy

Partial Onset Seizures

Germany, United States, Hungary, Korea, Republic of, Poland, Slovakia
Neurocrine Biosciences

Terminated

Extension Study to Evaluate the Safety and Tolerability of NBI-921352 When Used With Anti-seizure Medications in Adults With Focal Onset Seizures

Focal Onset Seizure | Focal Onset Epilepsy

Spain, Australia, Belgium, Czechia, France, Hungary, Italy
Novartis

Withdrawn

Evaluate the Efficacy of BGG492 as Adjunctive Treatment in Patients With Refractory Partial Onset Seizures

Partial Onset Seizures

United States, Austria, Spain, Estonia, Bulgaria, Latvia, Canada, India, Belgium, Lithuania, Romania
Eisai Inc.

Completed

Evaluating Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refractory Partial Seizures

Refractory Partial Seizures

Hong Kong, Italy, Australia, Spain, Portugal, Taiwan, India, Thailand, Hungary, Poland, Bulgaria, Serbia, Russian Federation, Korea, Republic of, Ukraine, Romania, Latvia, Lithuania, Germany, Estonia, Czech Republic, Philippines, Ma...
Assiut University

Not yet recruiting

Comparison Between the Use of Phentolamine Versus Glyceryl Trinitrate for Their Effect on Renal Function in Pre-eclampsia Patients in ICU

Pre-eclampsia Aggravated | Pre-Eclampsia; Complicating Pregnancy
Eisai Inc.

Completed

Evaluating the Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refractory Partial Seizures

Refractory Partial Seizures

United States, Chile, Brazil, Canada, Mexico, Argentina
Eisai Inc.

Completed

To Evaluate The Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refractory Partial Seizures

Refractory Partial Seizures

United States, France, Germany, Italy, United Kingdom, Belgium, Israel, South Africa, Finland, Russian Federation, Austria, Netherlands, Sweden, India
Peking Union Medical College Hospital
Shijiazhuang Yiling Pharmaceutical Co. Ltd

Unknown

Aspirin as an add-on Treatment of Refractory Epilepsy in Tuberous Sclerosis Complex

Epilepsy | Tuberous Sclerosis Complex | Aspirin | Cognitive Decline | Skin Lesions

China
UCB Pharma

Completed

Post-Authorization Safety Study to Assess the Safety of Vimpat as add-on Therapy in Patients With Partial-onset Seizures (PASS)

Epilepsies, Partial

France, Germany, United Kingdom, Spain, Netherlands
GlaxoSmithKline

Completed

Clinical and Economic Burden of Uncontrolled Epilepsy: Analyses From a Medicaid Database and a Private Health Plan Database

Epilepsy
George Washington University
GlaxoSmithKline

Terminated

Lamictal in the Treatment of Post-Herpetic Neuralgia

Neuralgia, Postherpetic

United States
Tata Memorial Centre

Not yet recruiting

Short Versus Long-term Levetiracetam in Brain Tumors (LIBRA)

Seizures | Brain Tumors | Antiepileptics | Levetiracetam
Merck Sharp & Dohme LLC

Recruiting

A Study of Belzutifan (MK-6482) in Combination With Palbociclib Versus Belzutifan Monotherapy in Participants With Advanced Renal Cell Carcinoma (MK-6482-024/LITESPARK-024)

Renal Cell Carcinoma

United States, Australia, Israel
Page B. Pennell, MD
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Physiological-based Pharmacokinetics Approach to Medication Exposure During Pregnancy and Breastfeeding (PBPK)

Epilepsy | Pregnancy Related

United States
Nottingham University Hospitals NHS Trust
University of Nottingham

Recruiting

The Biomarkers of Neurological Disease in Utero Study (BONDING)

Epilepsy | Neurodevelopmental Disorders | Teratogenesis | Fetal Disease

United Kingdom
National Institute of Neurological Disorders and...

Recruiting

Investigating Epilepsy: Screening and Evaluation

Epilepsy | Seizures | Epilepsy, Temporal Lobe | Partial Epilepsy

United States
Marinus Pharmaceuticals

Withdrawn

To Evaluate the Efficacy, Safety, and Tolerability of Intravenous Ganaxolone Added to Standard of Care in Refractory Status Epilepticus (RSE)

Refractory Status Epilepticus

Spain, Switzerland, Germany, France, Austria, Italy, Belgium, United Kingdom, Czechia, Croatia, Finland, Lithuania, Israel, Hungary, Poland, Slovakia
Marinus Pharmaceuticals

Withdrawn

Safety and Efficacy Study of IV Ganaxolone as Adjuvant Therapy for Established Status Epilepticus (ESE)

Status Epilepticus

United States
University of Oxford
UCB Pharma; Oxford University Hospitals NHS Trust; Oxford Health NHS Foundation... and other collaborators

Completed

An Investigation of Levetiracetam in Alzheimer's Disease (ILiAD)

Epilepsy | Alzheimer Disease

United Kingdom
Istituti Clinici Scientifici Maugeri SpA

Active, not recruiting

Seizures and Traumatic Brain Injury Rehabilitation

Seizures | Traumatic Brain Injury

Italy
Assistance Publique - Hôpitaux de Paris

Terminated

Perampanel in Focal Status Epilepticus (PEPSI)

Epilepticus; Status, Focal Motor

France
Trakya University

Completed

The Relationship of Developing Metabolic Acidosis With Antiepleptic Drugs in Craniotomy Operations

Craniotomy | Metabolic Acidosis | Anesthesia Management | Antiepileptic Drugs

Turkey
Mayo Clinic
National Cancer Institute (NCI)

Terminated

Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy

Malignant Glioma | WHO Grade 3 Glioma | Intractable Epilepsy | Seizure Disorder | WHO Grade 2 Glioma

United States
University Hospital, Brest

Active, not recruiting

Comitial Prophylaxis in Neurosurgery in Patients Who Have Undergone Intracranial Surgery Programmed Supratentorial Surgery (Exeresis or Biopsy) Between 2019 and 2022 (PRO-CON)

Anti-epileptic Prophylaxis in Intracranial Neurosurgery

France
UCB Pharma

Completed

Brivaracetam Efficacy and Safety Study in Subjects With Partial Onset Seizures (BRITE)

Epilepsy

United States, Czechia, Germany, Poland, Austria, Belgium, Brazil, Bulgaria, Canada, Estonia, Finland, France, Hong Kong, Hungary, India, Italy, Japan, Korea, Republic of, Latvia, Lithuania, Mexico, Netherlands, Puerto Rico, Russian Federation and more
Eisai Inc.

Terminated

A Study to Evaluate the Pharmacodynamic Activity of E2730 in Adult Participants With Photosensitive Epilepsy

Photosensitive Epilepsy

United States
University of Twente
Radboud University Medical Center; University Medical Center Groningen; Maastricht... and other collaborators

Completed

TELSTAR: Treatment of ELectroencephalographic STatus Epilepticus After Cardiopulmonary Resuscitation (TELSTAR)

Cardiac Arrest | Status Epilepticus | Anoxic Encephalopathy

Netherlands, Belgium
University of Maryland, Baltimore

Completed

Pharmacokinetics of Antiepileptics in Patients on CRRT (PADRE)

Renal Insufficiency | Renal Failure | Acute Kidney Injury | Pharmacokinetics

United States
Rambam Health Care Campus

Terminated

Pharmacokinetics of Paracetamol and Antiepileptic Drugs After Sleeve Gastrectomy

Bariatric Surgery Candidate

Israel
Takeda
Ovid Therapeutics Inc.

Completed

A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-935 (OV935) as an Adjunctive Therapy in Pediatric Participants With Developmental and/or Epileptic Encephalopathies (ELEKTRA)

Epilepsy | Dravet Syndrome | Lennox-Gastaut Syndrome

United States, Canada, Israel, Poland, Spain, Australia, China, Portugal
Eisai Inc.

Terminated

A Study to Evaluate the Pharmacodynamic Activity of E2082 in Adult Participants With Photosensitive Epilepsy

Photosensitive Epilepsy

United States
Novelfarma Ilaç San. ve Tic. Ltd. Sti.
Novagenix Bioanalytical Drug R&D Center; Farmagen Ar-Ge Biyot. Ltd. Sti

Completed

Bioequivalence Study of Favipiravir 200 mg Film Tablet (Novelfarma, Turkey) Under Fasting Conditions (Favipiravir)

Bioequivalence

Turkey
Christoph P Hornik, MD MPH
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics of Anti-epileptic Drugs in Obese Children

Epilepsy | Obese

United States
Jiangxi Qingfeng Pharmaceutical Co. Ltd.

Unknown

Xiyanping Injection for the Treatment of New Coronavirus Infected Pneumonia

2019 Novel Coronavirus Pneumonia
Food and Drug Administration (FDA)
University of Maryland, Baltimore

Completed

Characterization of Epilepsy Patients BEEP 2b (BEEP2b)

Epilepsy

United States

Search clinical trials for: Anti-epileptic drug (AED)

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