Search clinical trials for: Breakthrough

Total 175 results

A.Menarini Asia-Pacific Holdings Pte Ltd

Completed

Observational Study of Efficacy, Safety and Tolerability of Fentanyl in Korean Cancer Patients (OASIS)

Breakthrough Cancer Pain

Korea, Republic of
Northwestern University
Bristol-Myers Squibb; American Cancer Society, Inc.; Melanoma Research Foundation...

Completed

Development of ImmunOncoTool (ACS-MRA)

Cancer | Cancer, Treatment-Related

United States
University Hospitals Cleveland Medical Center

Completed

Patient Controlled Intrathecal Analgesia With Bupivacaine for Chronic Low Back Pain

Chronic Pain | Breakthrough Pain | Pain, Intractable

United States
University Medical Centre Ljubljana

Completed

Impact of Vaccination in Acute COVID-19

COVID-19

Slovenia
Neurelis, Inc.

Completed

Repeat Dose Safety Study of NRL-1 in Epilepsy Subjects

Acute Repetitive Seizures | Breakthrough Seizures

United States
Bangkok Metropolitan Administration Medical College...

Completed

Antibody After COVID-19 Vaccination

Covid19 | CKD | Breakthrough Infection | Kidney Transplant | Vaccination

Thailand
Aziende Chimiche Riunite Angelini Francesco S.p.A

Terminated

Treatment of Breakthrough Cancer Pain According to European Guidelines (BEG)

Breakthrough Cancer Pain

Poland
William Beaumont Hospitals

Completed

The Impact of Vaccination on Severity of Illness in COVID-19

Covid19

United States
Boston Scientific Corporation
EKOS Corporation

Completed

Treatment of Chronic Deep Vein Thrombosis (DVT) and Post-Thrombotic Syndrome (PTS) With the EkoSonic® Endovascular System (ACCESS PTS)

Deep Vein Thrombosis | Post-thrombotic Syndrome

United States
Nova Southeastern University

Completed

TDN, Manual Therapy and Exercise For the Management of Achilles Tendinopathy

Achilles Tendon Injury

United States
M.D. Anderson Cancer Center
Archimedes Pharma US, Inc.

Terminated

Fentanyl for Breakthrough Pain in the Emergency Department

Pain

United States
Shire

Terminated

SPD489 Adult Major Depressive Disorder (MDD) Open-label Safety and Tolerability Rollover Extension Study

Major Depressive Disorder

United States, Spain, Germany, Puerto Rico, Canada, Estonia, South Africa, Czechia, Finland, Chile, Hungary, Mexico, Poland, Romania
Shire

Completed

Efficacy and Safety Study of SPD489 in Combination With an Antidepressant in the Treatment of Adults With Major Depressive Disorder

Major Depressive Disorder

United States, Germany, Sweden, Poland, South Africa, Belgium, Czechia, Estonia, Finland, Hungary, Romania
Shire

Completed

Study of C1 Inhibitor (Human) for the Prevention of Angioedema Attacks and Treatment of Breakthrough Attacks in Japanese Subjects With Hereditary Angioedema (HAE)

Hereditary Angioedema (HAE)

Japan
H. Lundbeck A/S

Completed

Real-life Effectiveness of Vortioxetine in Depression (RELIEVE)

Major Depressive Disorder

United States, Canada, France, Italy
M.D. Anderson Cancer Center
INSYS Therapeutics Inc

Terminated

Sublingual Fentanyl for the Management of Breakthrough Pain

Advanced Cancers

United States
Boston Scientific Corporation

Completed

VIRTUS: An Evaluation of the Vici™ Venous Stent System in Patients With Chronic Iliofemoral Venous Outflow Obstruction (VIRTUS)

Chronic Venous Disorder | Venous Outflow Obstruction | Symptomatic Venous Outflow Obstruction of Iliofemoral Vein

United States, Ireland, United Kingdom, Netherlands, France, Germany, Spain
Taichung Veterans General Hospital

Completed

Clinical Course Study in Chronic Hepatitis B After Nucleos(t)Ide Analogue Therapy

Prognosis | Virological Breakthrough

Taiwan
Centre Hospitalier Universitaire Vaudois

Unknown

Breakthrough Invasive Mold Infections Under Posaconazole Prophylaxis (BIMI) (BIMI)

Hematologic Diseases | Hematologic Malignancy | Invasive Mold Infections | Breakthrough Invasive Mold Infections

Switzerland, Austria, Germany
M.D. Anderson Cancer Center
INSYS Therapeutics Inc

Completed

Fentanyl Sublingual Spray for Exercise-Induced Breakthrough Dyspnea

Advanced Cancers

United States
C. R. Bard

Completed

BARD® The VENOVO™ Venous Stent Study for Treatment of Iliofemoral Occlusive Disease (VERNACULAR)

Peripheral Vascular Disease | Venous Disease | May-Thurner Syndrome | Iliofemoral Occlusive Disease

United States, Australia, Germany, Ireland, Netherlands, Spain, United Kingdom
Lee's Pharmaceutical Limited

Unknown

Effectiveness and Tolerance of Inhaled Fentanyl Aerosol (25µg/Dose) in Chinese Patients With Breakthrough Cancer Pain

Breakthrough Cancer Pain
University of Hawaii
Meharry Medical College; Charles Drew University of Medicine and Science

Completed

Oral Contraceptives and Subantimicrobial Doxycycline: Effect on Endometrial Matrix Metalloproteinases

Breakthrough Bleeding

United States
Prostrakan Pharmaceuticals

Completed

Long-term Safety Study of Sublingual Fentanyl Tablets in Cancer Patients

Pain | Cancer

United States
Rex Medical
Syntactx

Completed

Revolution™ Peripheral Atherectomy System for Lower Extremity Peripheral Arterial Revascularization (REVEAL)

Peripheral Artery Disease

United States
M.D. Anderson Cancer Center
Teva Pharmaceuticals USA

Completed

Fentanyl Buccal Tablets for Exercise Induced Breakthrough Dyspnea

Advanced Cancers

United States
Kyowa Kirin Co., Ltd.

Completed

A Phase III Clinical Study of KW-2246 for Breakthrough Pain in Cancer Patients

Pain, Cancer

Japan
Oregon Health and Science University
Merck Women's Health Investigator Initiated Studies Program

Completed

Treatment of Unfavorable Bleeding Patterns in Contraceptive Implant Users (Tamoxifen/BTB)

Bleeding | Breakthrough Bleeding | Implants

United States
UNICANCER

Withdrawn

Effectiveness and Tolerance of Fentanyl Citrate in Painful Pain Induced During Diagnostic or Therapeutic Examinations in Cancer Patients (FARADI)

Breakthrough Pain
Angelini Farmacéutica
Apices Soluciones S.L.

Completed

Quality of Life Study Breakthrough Cancer Pain Treated in Medical Oncology Services (CAVIDIOM) (CAVIDIOM)

Breakthrough Pain

Spain
Takeda

Completed

Characterisation and Epidemiology of Breakthrough Cancer Pain in Spain

Breakthrough Cancer Pain

Spain
BioDelivery Sciences International

Completed

Study of BEMA™ Fentanyl in the Treatment of Breakthrough Pain in Cancer Subjects

Pain | Cancer

United States
Member Companies of the Opioid PMR Consortium

Terminated

Discontinuation vs Continuation of Long-term Opioid Therapy in Suboptimal and Optimal Responders With Chronic Pain

Opioid-Related Disorders | Drug Abuse | Opiate Addiction | Narcotic Abuse

United States
AHS Cancer Control Alberta
University of Calgary

Terminated

Sublingual Methadone for the Management of Cancer-related Breakthrough Pain in Outpatients

Pain | Cancer

Canada
Oregon Health and Science University

Completed

Tamoxifen to Reduce Unscheduled Bleeding in New Users of the Levonorgestrel-releasing Intrauterine System (LNG-IUS)

Metrorrhagia | Menorrhagia | Medicated Intrauterine Devices

United States
Central Hospital, Nancy, France

Completed

Analgesic Efficacy of Transmucosal Fentanyl for Breakthrough Pain Caused by Interventional Gastrostomy (ANTALGIP)

Gastrostomy | Breakthrough Pain | Upper Aerodigestive Tract Neoplasms

France
Institute of Cancer Research, United Kingdom
King's College London; Cancer Research UK; Breakthrough Breast Cancer

Unknown

Triple Negative Breast Cancer Trial (TNT)

Breast Cancer

United Kingdom
Assiut University

Unknown

A Comparison Between Surgical Techniques for Securing Conjunctival Autografting in Primary Pterygium Surgery

Pterygium
University Hospital, Basel, Switzerland

Terminated

Comparison of Oral Morphine Versus Nasal Ketamine Spray With Chitosan in Cancer Pain Outpatients (ONKEMI)

Cancer: Breakthrough Pain | Cancer: Extreme Pain on Movement

Switzerland
Chang Gung Memorial Hospital
TTY Biopharm

Completed

A Dose Titration Study of Fentanyl Buccal Soluble Film for Breakthrough Cancer Pain in Taiwan

Breakthrough Cancer Pain

Taiwan
U.S. Army Medical Research and Development Command
Walter Reed Army Institute of Research (WRAIR); Mahidol University; Sanofi Pasteur... and other collaborators

Completed

Follow up of Thai Adult Volunteers With Breakthrough HIV Infection After Participation in a Preventive HIV Vaccine Trial

HIV-1

Thailand
S. Andrea Hospital

Completed

Barriers and Breakthroughs in IMPlementing Split Regimen OVEr Single Dose (IMPROVES)

Colonoscopy: Bowel Preparation
Columbia University

Completed

Comparison of Epidural Fentanyl and Clonidine for Breakthrough Pain

Labor Pain

United States
Dr. Reddy's Laboratories Limited

Completed

DFN-02 Open Label Safety Study in Patients With Acute Migraine

Acute Migraine

United States
Angelini Farmacéutica

Completed

Quality of Life Study in Patients With Cancer Breakthrough Pain Treated in Palliative Care Units (CAVIDIOPAL)

Breakthrough Pain

Spain
Angelini Farmacéutica

Completed

Quality of Life Study Breakthrough Cancer Pain Treated in Radiation Oncology Services With Palliative Intent (CAVIDIOR)

Breakthrough Pain

Spain
University of Louisville
James Graham Brown Cancer Center

Withdrawn

An Assessment of the Ability of Fentanyl Citrate Nasal Spray to Manage Breakthrough Pain in Cancer Patients. (FCNS)

Pain

United States
Melanoma Research Foundation Breakthrough Consortium
Genentech, Inc.

Terminated

Trial of Vemurafenib/Cobimetinib With or Without Bevacizumab in Patients With Stage IV BRAFV600 Mutant Melanoma

Melanoma | Metastatic Melanoma

United States
AHS Cancer Control Alberta
Calgary Health Region

Completed

Sublingual Methadone for the Management of Cancer Breakthrough Pain

Pain | Cancer
Brigham and Women's Hospital
Endo Pharmaceuticals

Completed

The Efficacy of Diclofenac Gel for Breakthrough Pain and the Neuropathic Components of Pain in Knee Osteoarthritis

Knee Osteoarthritis

United States

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