Search clinical trials for: DDI

Total 306 results

Seno Medical Instruments Inc.

Completed

The PIONEER-01 Study of the Imagio Breast Imaging System

Breast Cancer

United States
The Aurum Institute NPC
Johns Hopkins University; University of California

Completed

Safety Tolerability DDI Short Course Treatment of LTBI Infection With High-dose Rifapentine and Isoniazid or Standard Isoniazid Preventive Therapy in HIV+ Patients (DOLPHIN & DOLPHIN TOO) (IMPAACT4TB)

HIV Infections | Respiratory Tract Infections

South Africa
Novartis Pharmaceuticals
Medicines for Malaria Venture

Completed

Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Efavirenz

Malaria

United Kingdom
Jiangsu HengRui Medicine Co., Ltd.

Completed

Effect of Montmorillonite Power or Loperamide on the Pharmacokinetics of Pyrotinib in Healthy Subjects

HER2-positive Recurrent / Metastatic Breast Cancer

China
Sunshine Lake Pharma Co., Ltd.

Completed

Pharmacokinetics of Midazolam When Co-administered With HEC74647 and HEC110114

Healthy Subjects

China
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

A Trial of DDI Between SHR1459 and Efavirenz With Healthy Subjects

B-cell Tumors

China
Altimmune, Inc.

Completed

ALT-801 DDI Study in Healthy Volunteers

NASH - Nonalcoholic Steatohepatitis

Australia
Novartis Pharmaceuticals
Medicines for Malaria Venture

Completed

Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and Dolutegravir

Malaria

United Kingdom
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Drug-drug Interaction Trial of Loperamide Pharmacokinetics Effect on Pyrotinib Maleate

Healthy Participants

China
Novartis Pharmaceuticals
Medicines for Malaria Venture

Completed

Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Itraconazole

Malaria

United Kingdom
Sunshine Lake Pharma Co., Ltd.

Active, not recruiting

A Study to Evaluate Drug-Drug Interaction of Larotinib With Itraconazole and Rifampin in Healthy Adult Participants (Z650)

Healthy Volunteers

China
Seoul National University Hospital

Completed

Evaluation of Metabolic Markers for the Prediction of DDI of Various CYP3A Substrates and Inhibitors

Healthy

Korea, Republic of
Hutchmed

Completed

Fruquintinib DDI Study With P-gp and BCRP Substrates

Metastatic Colorectal Cancer

United States
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

DDI Study of Evobrutinib and Carbamazepine

Healthy

Germany
Italfarmaco

Completed

Perpetrator DDI Potential of Givinostat as Inhibitor and Inducer of CYP3A and P-gp Activity

Drug-Drug Interaction

Portugal
Beijing InnoCare Pharma Tech Co., Ltd.

Completed

DDI Study of Orelabrutinib

Healthy Person

China
Merck Sharp & Dohme LLC

Completed

MK-1942/Donepezil Interactions in Participants With Alzheimer's Disease (MK-1942-005) (DDI)

Alzheimer's Disease

United States
Abdul Wali Khan University Mardan

Completed

Drug-Drug Interaction Study of Voriconazole With Clarithromycin.

Healthy

Pakistan
Blade Therapeutics

Completed

Drug-Drug Interaction (DDI) Study in Healthy Volunteers

Drug Drug Interaction

Australia
Aurinia Pharmaceuticals Inc.

Completed

Drug-Drug Interaction Study to Investigate Effects of Voclosporin on Pharmacokinetics of Simvastatin (Statin-DDI)

Drug-drug Interaction

United States
Blade Therapeutics

Completed

Dedicated Drug-Drug Interaction (DDI) Study in Healthy Volunteers

Drug Drug Interaction

United States
Loxo Oncology, Inc.
Eli Lilly and Company

Completed

A Drug Drug Interaction (DDI) Study of Pirtobrutinib (LY3527727) and Rosuvastatin in Healthy Participants

Healthy

United States
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Completed

A Study to Evaluate the Drug-drug Interactions (DDIs) of DBPR108 With Warfarin Sodium, Digoxin, Probenecid in Healthy Subjects

Healthy Subjects

China
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Safety and Effectiveness of Emtricitabine, Efavirenz, and Didanosine in HIV Infected Children Who Have Taken Few or No Anti-HIV Drugs

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Completed

A Phase II Double-Blind Study of Delavirdine Mesylate ( U-90152 ) in Combination With Zidovudine ( AZT ) and/or Didanosine ( ddI ) Versus AZT and ddI Combination Therapy

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I Safety, Efficacy, and Pharmacokinetic Study of 2',3'-Dideoxyinosine (ddI) Administered Twice Daily to Patients With AIDS or AIDS Related Complex

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Virologic Responses To New Nucleoside Regimens After Prolonged ZDV or ddI Monotherapy

HIV Infections

United States, Puerto Rico, Tanzania
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Hoffmann-La Roche

Completed

A Prospective, Randomized, Open-Label, Comparative Trial of Dideoxyinosine (ddI) Versus Dideoxycytidine (ddC) in HIV-Infected Patients Who Are Intolerant of or Who Have Failed Zidovudine (AZT) Therapy

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Glaxo Wellcome; Upjohn

Completed

A Phase I Concentration-Controlled Trial to Assess the Safety, Tolerance, Pharmacokinetics and Development of Decreased HIV-1 Susceptibility to the Combination of Atevirdine Mesylate (U-87201E), Zidovudine (AZT), and Didanosine (ddI)

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Comparison of Zidovudine (AZT) Used Alone or in Combination With Didanosine (ddI) or Dideoxycytidine (ddC) in HIV-Infected Patients

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Glaxo Wellcome; Upjohn

Completed

A Phase I Concentration-Targeted Multidose Study of Atevirdine Mesylate ( U-87201E ), AZT, and ddI or ddC

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

Comparison of 2',3'-Dideoxyinosine (Didanosine, ddI) and Zidovudine in Therapy of Patients With the AIDS Dementia Complex

HIV Infections | AIDS Dementia Complex

United States
National Institute of Allergy and Infectious Diseases...

Completed

Anti-HIV Drugs for Treating Infants Who Acquired HIV Infection at Birth

HIV Infections
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

A Randomized Comparative Trial of Zidovudine (AZT) Versus 2',3'-Dideoxyinosine (ddI) Versus AZT Plus ddI in Symptomatic HIV-Infected Children

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Completed

The Safety and Effectiveness of Hydroxyurea and ddI Used Individually or Together in HIV-Infected Patients

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb

Completed

A Study of Dideoxyinosine (ddI) in HIV-Infected Children Who Have Not Had Success With Zidovudine or Who Cannot Take Zidovudine

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb

Completed

A Phase I Trial to Evaluate Didanosine (ddI) in HIV-Infected Pregnant Women

HIV Infections | Pregnancy

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Novum

Completed

A Study of Chemotherapy Plus ddI or ddC in the Treatment of AIDS-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I Study of Combination Therapy With Didanosine (ddI) and Ribavirin in HIV-Infected Children.

HIV Infections

United States, Puerto Rico
Jiangsu HengRui Medicine Co., Ltd.

Completed

Effect of Fluconazole on the Pharmacokinetics of Pyrotinib in Healthy Subjects

Healthy Subjects

China
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Completed

A Study to Investigate the Drug-drug Interactions (DDIs) Between SKLB1028 and Midazolam in Healthy Subjects

Healthy Subjects

China
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Active, not recruiting

A Study to Investigate the Drug-drug Interactions (DDIs) of SKLB1028 With Itraconazole, Gemfibrozil or Rifampicin in Healthy Subjects

Healthy Subjects

China
Impact Therapeutics, Inc.

Completed

IMP4297 DDI (Drug-Drug Interaction)Trial in Healthy Male Volunteers

Solid Tumor

China
Ascletis Pharmaceuticals Co., Ltd.

Completed

Study to Evaluate the Effects of Itraconazole and Rifampin on the Pharmacokinetics of ASC40 in Healthy Subjects

Healthy

China
La Fundacion Favaloro para la Investigacion y la...
Fundación de Ciencias Exactas - UNLP

Enrolling by invitation

ImpRovE underSTanding of Short bOwel syndRome in Latin-amErica (RESTORE)

Short Bowel Syndrome

Argentina
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Completed

A Study to Evaluate the DDI of DBPR108 With Metformin,Glibenclamide,Valsartan, or Simvastatin in Healthy Subjects

Healthy Subjects

China
Gannex Pharma Co., Ltd.

Completed

DDI Study of ASC41 in HV and the PK, Safety and Tolerability in Subjects With NAFLD.

Healthy | NAFLD

United States
Hutchison Medipharma Limited

Completed

Surufatinib DDI With a PPI and a CYP3A Inducer

Healthy

United States
Parc de Salut Mar
Hospital Infantil Universitario Niño Jesús, Madrid, Spain; Hospital Universitario... and other collaborators

Completed

Pediatric Exploratory Research Study of EGCG Use and Safety (PERSEUS) (PERSEUS)

Down Syndrome | Fragile X Syndrome

Spain
University Hospital, Brest

Completed

Comparison of Two D-Dimers Dosing Techniques (COMPADDI)

Blood Coagulation Disorder

France

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