Search clinical trials for: Dose Tolerance

Total 23249 results

University Hospital, Montpellier

Active, not recruiting

Oral Low Doses Tolerance INduction Study for Peanuts (OLDTINYpeanut)

Peanut Allergy

France
Lee's Pharmaceutical Limited

Unknown

Effectiveness and Tolerance of Inhaled Fentanyl Aerosol (25µg/Dose) in Chinese Patients With Breakthrough Cancer Pain

Breakthrough Cancer Pain
Clinical Nutrition Research Center, Illinois Institute...

Completed

Dose-dependent Effect of Grape Seed Extract on Glucose Control in People With Impaired Glucose Tolerance (GSE3)

Impaired Glucose Tolerance

United States
Assistance Publique - Hôpitaux de Paris

Completed

Dose Finding Study of Il-2 at Ultra-low Dose in Children With Recently Diagnosed Type 1 Diabetes (DFIL2-Child)

Type 1 Diabetes

France
Tiedra Farmacéutica SL
Hospital Universitario Principe de Asturias

Unknown

Efficacy and Tolerance of Hypertonic Sodium Chloride (NaCl 5%) Eye Drops Without Preservatives in Corneal Edema

Corneal Edema

Spain
Louis Stokes VA Medical Center

Suspended

Trazodone Dose Tolerance and APAP Adherence (TrazoDose)

Sleep Apnea, Obstructive

United States
University of Saskatchewan

Completed

Regular Use Effect of Inhaled Ipratropium Bromide on Airway Responsiveness to Methacholine in Well-controlled Asthma

Asthma

Canada
Merck Sharp & Dohme LLC

Completed

Dose Response Finding Study of MK-0431/ONO-5435 in Japanese Subjects With Impaired Glucose Tolerance (MK-0431-105)

Glucose Intolerance
King's College London
King's College Hospital NHS Trust

Terminated

Low-dose IL-2 for Treg Expansion and Tolerance (LITE) (LITE)

Liver Diseases | Transplantation

United Kingdom
Memorial Sloan Kettering Cancer Center
Tufts Medical Center; Lahey Clinic

Completed

Lenalidomide (Revlimid®) Plus Low-dose Dexamethasone (Ld x 4 Cycles) Then Stem Cell Collection Followed by Randomization to Continued Ld or Stem Cell Transplantation (SCT) Plus Maintenance L

Multiple Myeloma

United States
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Completed

The Tolerance, Pharmacokinetics of Jaktinib in Healthy Volunteers

Healthy Volunteers

China
Odense University Hospital
University of Southern Denmark

Completed

Dose-response Effect of Pine Nut Oil as a Dual FFA1 and FFA4 Agonist on Glucose Tolerance in Healthy Humans.

Type 2 Diabetes Mellitus

Denmark
Pfizer

Completed

A Study In Healthy People Of Multiple Doses Of UK-396,082 Given By Mouth, To Investigate The Safety, Toleration And Time Course Of Blood Concentration Of UK-396,082 And Its Effects.

Safety | Pharmacokinetic | Phase 1 | Multiple Dose | Toleration

Belgium
Pfizer

Completed

Study To Evaluate Safety And Tolerability Of Single And Multiple Ascending Doses Of PF- 06260414 In Healthy Western And Japanese Male Subjects

Healthy

United States
Institut National de la Santé Et de la Recherche...

Terminated

Tolerance and Activity Evaluation of High Doses of Favipiravir Against Ebola Virus in the Semen (FORCE)

Ebola Virus Survivor

Guinea
National Institute of Allergy and Infectious Diseases...
Immune Tolerance Network (ITN)

Terminated

BMT and High Dose Post-Transplant Cyclophosphamide for Chimerism Induction and Renal Allograft Tolerance

Kidney Transplantation

United States
Hospices Civils de Lyon

Completed

Efficacy of Levocetirizine Fourfold Dosage in Chronic Spontaneous Urticaria (LEVURE PLUS)

Chronic Spontaneous Urticaria
GlaxoSmithKline

Completed

Repeat Dose Study of Controlled-Release Paroxetine Tablets and Immediate-Release Paroxetine Tablets in Healthy Japanese Male Subjects

Depressive Disorder

Japan
GlaxoSmithKline

Completed

Single Dose Study of Controlled-Release Paroxetine Tablets in Healthy Japanese Male Subjects

Depressive Disorder

Japan
National Institute of Allergy and Infectious Diseases...
Juvenile Diabetes Research Foundation; Immune Tolerance Network (ITN)

Terminated

A Research Trial of Aralast in New Onset Diabetes (RETAIN) (RETAIN)

Diabetes Mellitus, Type 1

United States
Shenyang Sunshine Pharmaceutical Co., LTD.

Completed

A Trial With Humanized TNFα Monoclonal Antibody Injection by Single Dose and Dose Escalation in Healthy Subjects

Rheumatoid Arthritis

China
National Institute of Allergy and Infectious Diseases...
Immune Tolerance Network (ITN)

Completed

High-Dose Immunosuppression and Autologous Transplantation for Multiple Sclerosis (HALT MS) Study

Relapsing-Remitting Multiple Sclerosis

United States
Assistance Publique - Hôpitaux de Paris

Suspended

Treatment of the Bilateral Severe Uveitis by IVT of Regulator T-cells: Study of Tolerance of Dose (UVEREG)

Uveitis

France
Valexfarm

Completed

Remegal Different Doses in Patients With Refractory Partial Seizures

Self Efficacy | Drug Safety | Normal Drug Tolerance

Russian Federation
Drugs for Neglected Diseases

Terminated

Multiple Dose Study to Evaluate Security, Tolerance and Pharmacokinetic of Fexinidazole (Drug Candidate for Human African Trypanosomiasis) Administered With a Loading Dose and With Food

Trypanosomiasis, African

France
University of Texas Southwestern Medical Center

Terminated

Pharmacokinetics of Low Dose Ketamine Infusion

Sedation | Opioid Tolerance

United States
Milton S. Hershey Medical Center

Withdrawn

A Pilot Study Comparing Tolerance of Oral Heme Iron Polypeptide With Oral Ionic Iron

Iron Deficiency

United States
Centre Hospitalier Universitaire, Amiens

Completed

Administration of Subcutaneous Teicoplanin in the Treatment of Osteoarticular Infections: Tolerance Study (TEICOPLANIN)

Osteoarticular Infection

France
ANRS, Emerging Infectious Diseases
Institut Pasteur; Hôpital Necker-Enfants Malades; Hospital Avicenne; CHU Kamenge... and other collaborators

Unknown

Study Evaluating Efficiency and Tolerance of High-dose Fluconazole Associated With Flucytosine as Induction Therapy for Cryptococcal Meningitis Associated With HIV in Sub-saharan Africa (Flucocrypto)

HIV | Cryptococcal Meningitis

Burundi, Côte D'Ivoire
University of Roma La Sapienza

Unknown

Low-dose Combination of Three Antihypertensive Drugs (3D)

Arterial Hypertension

Italy
Johns Hopkins University
Boehringer Ingelheim

Completed

Pharmacokinetic (PK) Study of Single-dose Rosuvastatin and Tipranavir/Ritonavir in Healthy Subjects

HIV Infections

United States
Julia Finkel

Completed

Low Dose Ketamine Study on Opioid Tolerance and Hyperalgesia (KPSF)

Idiopathic Scoliosis | Spondylolisthesis

United States
McGill University Health Centre/Research Institute...

Unknown

Morphine, Dyspnea, Exercise and COPD

Chronic Obstructive Pulmonary Disease

Canada
Yonsei University

Completed

Randomized, Open Labeled Clinical Trial to Compare the Effectiveness of Amlodipine/Valsartan vs Hydrochlorothiazide/Telmisartan on Glucose Tolerance in Patients With Hypertension With Metabolic Syndrome

Hypertension

Korea, Republic of
Delta Crystallon BV

Completed

Safety and Dose-finding Study of DC-TAB in Healthy Subjects

Multiple Sclerosis

Netherlands
Assistance Publique Hopitaux De Marseille

Completed

Assessing the Impact of the Early and Systematic Hormonal Replacement After Radio-isotopic Ablation of Graves'hyperthyroïdism on Quality of Life, Efficiency and Tolerance

Graves Disease (Basedow's Disease)

France
Institut Paoli-Calmettes

Unknown

Tolerance and Efficacy of Subcutanous Low Doses Rituximab for CLL Consolidation Treatment (LLCRlowdoz)

Chronic Lymphocytic Leukemia

France
Drexel University
Wyeth is now a wholly owned subsidiary of Pfizer

Withdrawn

Effect of Methylnaltrexone (Relistor) on Digestion and Tolerance to Tube Feeding in Patients Treated With Opiates

Tube Feeding

United States
Cambridge University Hospitals NHS Foundation Trust

Completed

Study of Tolerance to Oral Peanut (STOP)

Peanut Allergy

United Kingdom
VA Pharmacy Benefits Management Strategic Healthcare...

Completed

Tolerance to Target Doses of Thiazides in Actual Practice: A Feasibility Study

Hypertension

United States
Boehringer Ingelheim

Completed

Safety, Tolerance, and Pharmacokinetics of BILN 2061 ZW in Healthy Male Subjects, Combined With Preliminary Evaluation of Food Effect

Healthy
Boehringer Ingelheim

Terminated

Increasing Dose Tolerance Study in Healthy Male Volunteers After Administration of BIII 890 CL

Healthy
Boehringer Ingelheim

Completed

Dose Tolerance Study in Healthy Male Volunteers After Intranasal Application of Epinastine Nasal

Healthy
Boehringer Ingelheim

Completed

Safety, Tolerance, and Pharmacokinetics of Single Rising Oral Doses of BILB 1941 ZW Solution in Healthy Male Subjects, Followed With Bioavailability Comparison of BILB 1941 ZW Tablet and Solution Formulation Administered With or Without Food

Healthy
Anne Katrine Pagsberg
Albert Einstein College of Medicine; The Research Council for Health and Disease... and other collaborators

Unknown

Tolerance and Effect of Antipsychotics in Children and Adolescents With Psychosis (TEA)

Psychosis

Denmark
Boehringer Ingelheim

Completed

A Study to Determine Acute (After First Dose) and Chronic (After 28 Days) Effects of Empagliflozin (BI 10773) on Pre and Postprandial Glucose Homeostasis in Patients With Impaired Glucose Tolerance and Type 2 Diabetes Mellitus and Healthy Subjects

Diabetes Mellitus, Type 2

Austria, Germany, Italy
Cancer Advances Inc.

Terminated

A Study of the Safety and Tolerance of Three Doses of G17DT in Metastatic Colorectal Cancer (CC1C)

Colorectal Cancer
Boehringer Ingelheim

Completed

Single Increasing Dose Followed by Maintenance Dose Tolerance Study of BIIR 561 CL in Healthy Male Volunteers

Healthy
Boehringer Ingelheim

Completed

Single Dose Followed by Maintenance Dose Tolerance Study of BIIR 561 CL in Healthy Elderly Male and Female Volunteers

Healthy
Boehringer Ingelheim

Completed

Single Increasing Dose Tolerance Study in Healthy Male Volunteers of BIIR 561 CL

Healthy

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