Search clinical trials for: Excretion

Total 461 results

Cyclacel Pharmaceuticals, Inc.

Active, not recruiting

Absorption, Metabolism, and Excretion of CYC065 in Healthy Male Subjects

Healthy

United States
Columbia University
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Stress, Salt Excretion, and Nighttime Blood Pressure (SABRE)

Blood Pressure | Psychological Stress

United States
Reata, a wholly owned subsidiary of Biogen

Completed

A Phase I Study to Investigate the Absorption, Metabolism and Excretion in Healthy Male Subjects

Healthy

United States
The Cleveland Clinic

Active, not recruiting

Consumption of Oral Artificial Sweeteners on Platelet Aggregation and Polyol Excretion (COSETTE)

Cardiovascular Risk Factor

United States
Ascentage Pharma Group Inc.

Completed

The Absorption, Metabolism and Excretion of [14C]APG-2575 in Healthy Subjects

Pharmacokinetics

China
Soroka University Medical Center

Completed

Troponin Excretion in Urine in Patients With and Without Chronic Kidney Disease

Chronic Kidney Diseases | Acute Myocardial Infarction

Israel
Universidad Autonoma de Baja California

Completed

Education to Decrease in Sodium Intake Evaluated With 24 Hour Urinary Sodium Excretion (RCT) (RCT)

Hypertension | Diabetes Mellitus, Type 2 | Overweight or Obesity

Mexico
University of Alabama at Birmingham

Active, not recruiting

Oxalobacter Formigenes Colonization and Urinary Oxalate Excretion

Calcium Oxalate Urolithiasis

United States
University of Manitoba
Canadian Institutes of Health Research (CIHR); BioMark Technologies Inc.

Completed

Urinary Excretion of Acetylamantadine by Cancer Patients

Cancer

Canada
Sanofi

Completed

A Study to Evaluate Absolute Bioavailability, Absorption, Metabolism, and Excretion of Genz-112638 in Healthy Male Participants

Gaucher's Disease Type I
Brightseed
University of Arkansas; Biofortis Mérieux NutriSciences

Active, not recruiting

Bioavailability Study of Hemp Phenolics

Bioavailability | Metabolites | Excretion

United States
Maastricht University Medical Center

Withdrawn

Time to Excretion of Contrast, a Maastricht Prospective Observational Study (TEMPOS)

Renal Insufficiency | Acute Kidney Injury | Contrast-induced Nephropathy

Netherlands
Bristol-Myers Squibb

Completed

A Study to Evaluate the Absorption, Metabolism, and Excretion of [14C]BMS-986419 in Healthy Male Participants

Healthy Volunteers

United States
Genzyme, a Sanofi Company

Completed

Excretion Balance, Pharmacokinetics, and Metabolism Following of [14C]-Venglustat Administration in Healthy Male Subjects

Healthy Volunteers | Disorders of Sphingolipid Metabolism

United Kingdom
University Hospital, Ghent
Universitair Ziekenhuis Brussel

Completed

Pharmacokinetics of Ciprofloxacin in Pediatric Patients

Urinary Tract Infection | Pyelonephritis

Belgium
ChemoCentryx

Completed

A Study to Evaluate the Effect of CCX140-B on Urinary Albumin Excretion in Subjects With Type 2 Diabetes and Albuminuria

Type 2 Diabetes Mellitus | Diabetic Nephropathy

Netherlands
Amgen

Completed

A Study to Assess the Mass Balance Recovery (Absorption, Distribution, Metabolism and Excretion) of [14C]CCX168 in Healthy Participants

Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis

United States
Cognition Therapeutics
National Institute on Aging (NIA)

Completed

Study to Assess the Absorption, Metabolism, Excretion, and Mass Balance of CT1812 in Healthy Adult Male Subjects (COG0108)

Alzheimer Disease

United States
BeiGene

Completed

A Study to Investigate the Absorption, Metabolism and Excretion of [14C]-BGB-11417

Healthy Volunteers

United States
zr Pharma & GmbH

Completed

Absorption, Metabolism, and Excretion Following a Single Oral Dose of [14C]-Rucaparib (AME)

Solid Tumor

Hungary
Bristol-Myers Squibb

Completed

A Study to Evaluate the Absorption, Metabolism, and Excretion (ADME) of BMS-986435

Healthy Volunteers

United States
The University of Hong Kong
Haven of Hope Hospital; The Social Innovation and Entrepreneurship Development...

Completed

The Acceptability of Auto-wrapping Commode Chair in Elderly Residential Setting

Technology

Hong Kong
Amsterdam UMC, location VUmc

Completed

SGLT2 Inhibition: Uric Acid Excretion Study (UREX)

Type 2 Diabetes

Netherlands
Edgewise Therapeutics, Inc.

Completed

Absorption, Metabolism, Excretion and Absolute Bioavailability of EDG-5506 in Healthy Volunteers

Nervous System Diseases | Genetic Diseases, Inborn | Musculoskeletal Diseases | Muscular Diseases | Neuromuscular Diseases | Muscular Dystrophies | Muscular Disorders, Atrophic | Healthy Volunteer

United States
Insmed Incorporated

Completed

A Study of the Absorption, Metabolism, and Excretion of [14C]-Brensocatib Following a Single Oral Administration in Healthy Male Participants

Healthy Volunteers

United States
Duke University

Completed

Markers of Alzheimers Disease and Cognitive Outcomes After Perioperative Care (MADCO-PC)

Postoperative Delirium | Alzheimers Disease | Post Operative Cognitive Dysfunction

United States
University Hospital, Basel, Switzerland

Completed

Effect of Protein Supplementation on Plasma Sodium Levels and Urinary Urea Excretion in Patients With SIAD (TREASURE)

Syndrome of Inappropriate Antidiuresis (SIAD)

Switzerland
Bristol-Myers Squibb

Completed

A Study to Evaluate the Metabolism and Excretion of BMS-986369 in Healthy Male Participants

Healthy Participants

United States
Genentech, Inc.

Completed

Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-GDC-9545 Following a Single Oral Dose (Part 1) and to Evaluate the Absolute and Relative Bioavailability of Oral Capsule Formulations of GDC-9545 (Part 2) in Healthy Female Subjects of Non-Childbearing Potential

Healthy Volunteers

United Kingdom
Alexion Pharmaceuticals

Completed

Study of Radiolabeled ALXN2050 in Healthy Adult Males

Healthy

United States
Sagimet Biosciences Inc.

Active, not recruiting

Open-label Study of the Absorption, Metabolism, and Excretion of [14C]TVB-2640 Following a Single Oral Dose in Healthy Male Subjects

Healthy Volunteers

United States
Athira Pharma
Alturas Analytics, Inc.; Labcorp Drug Development Inc

Completed

A Study of the Absorption, Metabolism, and Excretion of [14C]-Fosgonimeton (ATH-1017)

Healthy Volunteers

United States
Bristol-Myers Squibb

Completed

A Study to Evaluate the Drug Levels of [14C]CC-99677 in Healthy Male Participants

Healthy Volunteers

United States
University Hospital, Ghent

Completed

Evaluation of Salt Status in Patients With Cystic Fibrosis

Cystic Fibrosis | Salt; Deficit (or Low)

Belgium
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Study of Absorption, Metabolism, Excretion, and Absolute Bioavailability of Carbon-14-Labelled [14C] Selpercatinib (LY3527723) in Healthy Male Participants

Healthy

United States
AnewPharma

Completed

The Absorption, Metabolism and Excretion of [14C]CM082 in Human

Advanced Solid Tumor

China
Amgen

Completed

A Study of the Absorption, Metabolism, and Excretion of [14C]-AMG 510 Following a Single Oral Dose in Healthy Male Subjects

Healthy Subjects

United States
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

Single Dose Study To Study The Absorption, Metabolism And Excretion Of Famitinib

Healthy Subjects

China
Johns Hopkins Bloomberg School of Public Health
McCormick Science Institute

Completed

Maintenance of Recommended Sodium Intake (SPICE)

Maintenance of Recommended Sodium Intake

United States
TenNor Therapeutics Limited

Completed

Absorption, Metabolism, and Excretion Study of [14C]-TNP-2092

Healthy

United States
University of California, Davis
Mars, Inc.

Completed

Flavanol Absorption, Metabolism and Excretion From Fruit-based Drinks and Other Food Matrixes

Healthy

United States
University of California, Davis
Mars, Inc.

Completed

Food Matrix Effect on Flavanol Absorption, Metabolism and Excretion: Methylxanthines

Healthy

United States
Chinese PLA General Hospital

Completed

24-hour Urinary Electrolyte Excretion in Chronic Kidney Disease

Chronic Kidney Diseases | Electrolyte Imbalance
Fundació Eurecat
Silicium Laboratories S.L.; San Antonio Technologies S.L.; Catholic University... and other collaborators

Completed

Effect of Three Silicon Based Food Supplements on the Urinary Excretion of Aluminum and Other Metals (SILIAL) (SILIAL)

Biological Availability | Aluminium Overload

Spain
AstraZeneca
Parexel

Terminated

Human Absorption, Distribution, Metabolism, and Excretion Study of [14C]Adavosertib (ADME)

Advanced Solid Tumors

United Kingdom
Pyramid Biosciences

Completed

A Phase 1 Study of the Absorption, Metabolism, and Excretion of [14C] PBI-200

Absorption, Metabolism and Excretion in Healthy Volunteers

United States
Bayer

Completed

Study on the Safety of the Drug BAY2395840 at Different Doses, the Way the Body Absorbs, Distributes and Excretes the Drug Including the Effect of Its Formulation (Tablet or Liquid) and the Effect of Food on the Absorption, Distribution or Excretion of the Drug in Healthy Male Participants

Endometriosis

Germany
AstraZeneca
Quotient Sciences

Completed

A Study to Investigate the Absolute Bioavailability, Absorption, Metabolism, Distribution and Excretion of [14C]AZD5363 (Capivasertib)

Healthy Volunteer

United Kingdom
Altavant Sciences GmbH
Covance; Altavant Sciences, Inc.

Completed

Pharmacokinetics and Excretion of Oral [14C]-Rodatristat Ethyl

Healthy

United States
University of Washington
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Brigham...

Completed

Vitamin D and Omega-3 Trial to Prevent and Treat Diabetic Kidney Disease (VITAL-DKD)

Diabetes

United States

Search clinical trials for: Excretion

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