Search clinical trials for: First Time in Humans

Total 458242 results

Cancer Institute and Hospital, Chinese Academy...

Recruiting

XELOX +Bev +Tislelizumab for First-line Treatment of MSS/pMMR RAS-mutated mCRC

Bevacizumab | Capecitabine | Metastatic Colorectal Cancer (mCRC) | Oxaliplatin | Tislelizumab | First-Line | MSS/pMMR | RAS-mutated

China
Fudan University

Recruiting

Liposomal Irinotecan Based FOLFIRI With Bevacizumab in First-line Treatment of Advanced Colorectal Cancer

Colorectal Cancer

China
Erasmus Medical Center

Not yet recruiting

First Time Right of Vancomycin

Pharmacokinetics | Vancomycin
The First Affiliated Hospital of Guangzhou Medical...

Recruiting

Nivolumab Combined With Chemotherapy in the Treatment of Primary Tracheal Squamous Cell Carcinoma (GALAXY-1)

Neoplasms | Antineoplastic Agents | Carcinoma, Squamous

China
Dr. Inge Winter
Universität Münster

Recruiting

The Effect of a Six Week Intensified Pharmacological Treatment for Schizophrenia Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. (INTENSIFY SZ)

Schizophrenia and Related Disorders | Early Treatment-Resistance

Austria, Germany, Italy, Spain, United Kingdom
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

A Phase II/III Study of HR070803 in Combination With Oxaliplatin, 5-fluorouracil, Calcium Folinate and Bevacizumab Versus FOLFOX in Combination With Bevacizumab for First-line Treatment of Advanced Colorectal Cancer

Colorectal Cancer

China
GCS Ramsay Santé pour l'Enseignement et la Recherche

Not yet recruiting

Comparison of Speech Therapy and Audioprosthetic Care in Older Adults With First-time Hearing Aids (CODITION)

Hearing Loss
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Early Stage Triple-Negative Breast Carcinoma

United States, Puerto Rico
The First Affiliated Hospital of Soochow University

Recruiting

TFBC Combined With UCBT in the Treatment of High-risk Malignant Hematological Diseases

Hematopoietic Stem Cell Transplantation | Malignant Hematological Diseases

China
University of Pennsylvania
National Institute of Mental Health (NIMH)

Recruiting

Human Learning of New Structured Information Across Time and Sleep

Sleep | Learning | Consolidation | Humans

United States
Simon Berthelot

Recruiting

The Right Care, for the Right Patient, at the Right Time, by the Right Provider: A Value-based Comparison of the Management of Ambulatory Patients With Acute Health Concerns in walk-in Clinics, Primary Care Physician Practices and Emergency Departments

Ambulatory Care | Costs | Quality of Care | Emergency Services, Hospital

Canada
University of Minnesota
National Institute of Mental Health (NIMH)

Recruiting

EPI-MINN: Targeting Cognition and Motivation - National

Schizophrenia | Schizophrenia Spectrum and Other Psychotic Disorders | Schizoaffective Disorder | Bipolar Disorder | Psychosis | Schizo Affective Disorder | Prodromal Schizophrenia | Major Depression With Psychotic Features | Schizophreniform Disorders | Unspecified Psychosis | Psychosis Nos/Other

United States
Weijia Fang, MD

Recruiting

Neoadjuvant Treatment of Tislelizumab Combined Chemotherapy for Locally Advanced Oral Squamous Cell Carcinoma ：A Single-arm, Prospective, Phase II Trial

Oral Squamous Cell Carcinoma

China
Cambridge University Hospitals NHS Foundation Trust
King's College London; Imperial College London; University College, London; Wellcome... and other collaborators

Recruiting

Cardiometabolic Health in First Time Pregnancy (POPPY)

Heart Diseases | Diabetes | Pregnancy Related | Cardiometabolic Health | Placental; Syndrome, Dysfunction

United Kingdom
Onward Therapeutics

Recruiting

First-in-human Study of OT-A201 in Patients With Selected Hematological Malignancies and Solid Tumors

Solid Tumor | Hematological Malignancy

France
Guangzhou Medical University
Peking University First Hospital; First Affiliated Hospital, Sun Yat-Sen University and other collaborators

Recruiting

Tranexamic Acid for the Prevention of Postpartum Hemorrhage in Pregnant Women With Placenta Previa (TRAPP)

Hemorrhage, Postpartum | Placenta Previa

China
Qilu Pharmaceutical Co., Ltd.

Recruiting

QL1706 Monotherapy or in Combination With Bevacizumab and XELOX as First-line Treatment of Unresectable Advanced or Metastatic CRC

Colorectal Carcinoma

China
Cytokinetics

Recruiting

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCM (MAPLE-HCM)

Obstructive Hypertrophic Cardiomyopathy (oHCM)

United States, Denmark, Spain, Netherlands, United Kingdom, France, China, Israel, Germany, Italy, Hungary, Canada
First Affiliated Hospital Xi'an Jiaotong University

Recruiting

Construction of a Database of Prognostic Risk Factors and Quality of Life of Patients With Primary Solid Malignant Cancers Receiving Immunotherapy for the First Time Based on Questionnaire Survey

Malignant Neoplasm

China
Shandong New Time Pharmaceutical Co., LTD

Not yet recruiting

A Phase II Study of Rulonilimab Combined With Chemotherapy in the First-Line Treatment for Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

NSCLC | Non-small Cell Lung Cancer | PD-1

China
Shanghai East Hospital

Not yet recruiting

Vonoprazan-containing Triple Therapy Versus Empiric Bismuth Quadruple Therapy for First-line Helicobacter Pylori Treatment: a Randomized Clinical Trial

Helicobacter Pylori Infection

China
Peking University First Hospital

Recruiting

Night-time Dexmedetomidine-esketamine Infusion and Sleep Quality With Mechanical Ventilation

Sleep Quality | Dexmedetomidine | Intensive Care Unit | Mechanical Ventilation | Esketamine

China
McMaster University

Recruiting

RCT Evaluating First Time Shoulder Dislocation (REDUCE)

Sport Injury | Shoulder Dislocation | Anterior Dislocation

Canada
Fengyun Wang
Wuhan University

Recruiting

Galectin-3 in Septic and Non-septic Acute Kidney Injury

Sepsis | Acute Kidney Injury

China
AstraZeneca
Parexel

Recruiting

A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA) (DOMINICA)

Asthma

Korea, Republic of, Spain, United States, Argentina, France, Italy, Taiwan, Germany, United Kingdom, Poland, Canada
The First Affiliated Hospital with Nanjing Medical...
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Neoadjuvant Study With Pyrotinib and Trastuzumab and Abraxane in Patients With HER2-enriched Breast Cancer

Breast Cancer

China
Fundacion Clinica Valle del Lili

Recruiting

Neonatal Thymus Transplantation in Humans (SUPERTHYM)

Safety Issues

Colombia
Changhai Hospital
Xiangya Hospital of Central South University; Fudan University; Xuzhou Central... and other collaborators

Recruiting

Efficacy of Second Forward-view Examination of Left Colon for Adenoma Detection During Colonoscopy

Colon Adenoma

China
ViiV Healthcare

Recruiting

A Study to Investigate Safety, Tolerability, and Pharmacokinetics (PK) of VH4524184 and the Potential for Changes in Cytochrome P450 3A (CYP3A) Activity

HIV Infections

United States
Shandong University
The First Affiliated Hospital of Zhengzhou University; Zibo Central Hospital; Peking University Care Luzhong Hospital and other collaborators

Not yet recruiting

The Effect of Time Intervals for Rescue Treatment on Eradication Effect of Helicobacter Pylori Infection

Helicobacter Pylori Infection

China
First Affiliated Hospital Xi'an Jiaotong University
LanZhou University; Tongji Hospital; The First Affiliated Hospital of Zhengzhou... and other collaborators

Recruiting

Intranasal Insulin Improves Postoperative Neurocognitive Disorders in Elderly Patients

Postoperative Neurocognitive Disorders

China
GlaxoSmithKline
Biological E. Limited

Recruiting

Safety and Immunogenicity of a Novel Conjugate Vaccine Against Salmonella Typhi and Salmonella Paratyphi A in Healthy Adults

Typhoid Fever

Belgium
Bristol-Myers Squibb
Eisai Inc.

Recruiting

A Study of MORAb-202 Versus Investigator's Choice Chemotherapy in Female Participants With Platinum-resistant High-grade Serous (HGS) Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Neoplasms, Ovarian

Australia, United States, Korea, Republic of, Chile, Belgium, Italy, Spain, Israel, Japan
Dr. Inge Winter
Universität Münster

Not yet recruiting

Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure (INTENSIFY)

Bipolar Depression | Major Depressive Disorder | Schizophrenia and Related Disorders

Israel
Wuxi Hisky Medical Technology Co Ltd
Zhongda Hospital, Medical School, Southeast University; Suzhou Municipal Hospital and other collaborators

Recruiting

Prevalence of MAFLD in Patients With Type 2 Diabetes in Jiangsu Province of China

Type 2 Diabetes Mellitus in Remission | Metabolic Associated Fatty Liver Disease

China
Nanjing First Hospital, Nanjing Medical University

Recruiting

The Exploreration of the Management for the Positive IAA in Patients With Type 2 Diabetes After Premix Insulin Therapy

Type 2 Diabetes Mellitus

China
Fudan University

Recruiting

The Efficacy and Safety of Fruquintinib Plus Chemotherapy as Second-line Treatment in Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

China
Shanghai Jiaolian Drug Research and Development...
Shanghai Pharmaceuticals Holding Co., Ltd

Recruiting

Study of B013 and Nab-Paclitaxel for Locally Advanced or Metastatic Triple Negative Breast Cancer

Triple Negative Breast Cancer (TNBC)

China
Nanjing First Hospital, Nanjing Medical University

Recruiting

Effects of Tirzepatide and Insulin Glargine on Glucolipid Metabolism and Brain Function in Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus

China
Jiandong Zhang

Recruiting

Low-dose Radiotherapy Combined With Conventional Radiotherapy After Immunotherapy Failure (FL001)

Cancer Patients

China
Columbia University

Not yet recruiting

Conservative Versus Operative - First Time Patella Dislocations

Patella Dislocation

United States
Fundació Sant Joan de Déu
Universidad Autonoma de Madrid; VU University of Amsterdam

Recruiting

A Scalable Psychological Intervention to Reduce Psychological Distress Among Workers of Assisted Living Facilities (REPICAL)

Depression | Anxiety | Psychological Distress

Spain
Huashan Hospital

Recruiting

Validity and Reliability Evaluation of the PRO-CTCAE for Adult-type Diffuse Gliomas Patients in Chinese Population (VERONICA)

Glioma | Patient Reported Outcome Measures | Adverse Effects | Self Report

China
Shanghai First Maternity and Infant Hospital

Not yet recruiting

2.Comparison of the Live Birth Rate of PGT Versus Expectant Management in Patients With RPL

Pregnancy Outcome | Time-to-Pregnancy

China
Second Affiliated Hospital, School of Medicine,...

Recruiting

EXtending the Time Window for Thrombolysis in Posterior Circulation Stroke Without Early CT Signs

Stroke, Acute Ischemic

China
University of Nottingham

Recruiting

Prolonged Overnight Fast on Energy Metabolism and Skeletal Muscle Protein Synthesis in Humans

Time Restricted Feeding

United Kingdom
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
The First Affiliated Hospital with Nanjing Medical University; Second Affiliated... and other collaborators

Not yet recruiting

Efficacy of Transcutaneous Vagus Nerve Stimulation Paired With Tailor-Made Notched Music Therapy Versus Tailor-made Notched Music Training for Chronic Subjective Tinnitus

Female | Tinnitus, Subjective | Vagus Nerve Stimulation | Music Therapy | Male | Treatment Outcome | Humans | Double-Blind Method
Ningbo No. 1 Hospital

Not yet recruiting

Association Between Time in Range and In-hospital Outcomes in Type 2 Diabetic Patients With Acute Coronary Syndrome

Type 2 Diabetes Mellitus | Acute Coronary Syndrome

China
Gilead Sciences

Recruiting

Study of Sacituzumab Govitecan-hziy Versus Treatment of Physician's Choice in Patients With Previously Untreated Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer (ASCENT-03)

Triple Negative Breast Cancer | PD-L1 Negative

United States, Hong Kong, Belgium, Australia, Austria, Israel, Spain, Korea, Republic of, Taiwan, China, Japan, Netherlands, Brazil, Canada, Turkey, France, Germany, Malaysia, United Kingdom, Singapore, Hungary, Mexico, Italy, Switzer... and more
Sun Yat-sen University

Recruiting

The Effect of Meal Replacement on the Time to Reach the Blood Glucose Target in Patients With Type 2 Diabetes Mellitus

Diabetes | Blood Sugar; High

China

Search clinical trials for: First Time in Humans

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Denmark

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations