Search clinical trials for: Human Leucocyte Antigen

Total 25648 results

The Affiliated Hospital of Xuzhou Medical University
Xuzhou Medical University; IIT MediTech Co. Ltd

Recruiting

Study Of B7H3 CAR-T Cells in Treating Advanced Liver Cancer

Hepatocellular Carcinoma

China
Zagazig University

Recruiting

Candida Antigen and Bivalent HPV Vaccine in the Treatment of Multiple Warts

Warts | Human Papilloma Virus

Egypt
Firas El Chaer, MD

Recruiting

A Pilot Trial Using Isatuximab to Overcome Platelet Transfusion Refractoriness in Human Leukocyte Antigen Allo-Immunized Patients (SuppCare 001)

Hematologic Malignancy | Platelet Refractoriness

United States
Sechenov University
Pirogov Russian National Research Medical University

Recruiting

Human Leukocyte Antigen Class II (DRB1 and DQB1) Alleles and Haplotypes Frequencies in Patients With Pemphigus Vulgaris Among the Russian Population

Bullous Pemphigoid | Stevens-Johnson Syndrome | Toxic Epidermal Necrolyses | Pemphigus

Russian Federation
Trabzon Kanuni Education and Research Hospital

Recruiting

When to Apply to Which Patient in MSC? (MSC)

COVID-19 Acute Respiratory Distress Syndrome

Turkey
Mayo Clinic

Recruiting

A Vaccine (PDS0101) Alone or in Combination With Pembrolizumab for the Treatment of Locally Advanced Human Papillomavirus-Associated Oropharynx Cancer

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IVB Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Human Papillomavirus-Related Carcinoma | Locally Advanced Oropharyngeal Carcinoma

United States
Nanjing IASO Biotherapeutics Co.,Ltd

Not yet recruiting

A Study of Fully Human BCMA CAR-T (CT103A) in Patients With Newly Diagnosed High-risk Multiple Myeloma (FUMANBA-2)

Multiple Myeloma

China
The University of Hong Kong
Research Grant Council

Recruiting

Effects of Empagliflozin on Fibrosis and Cirrhosis in Chronic Hepatitis B

Cirrhosis | NAFLD | Chronic Hepatitis b | Fibrosis, Liver | Empagliflozin | SGLT2 Inhibitors

Hong Kong
Ciceri Fabio
Associazione Italiana per la Ricerca sul Cancro; Gruppo Italiano Trapianto...

Recruiting

Analysis of the Immunobiology of Acute Myeloid Leukemia Relapses After Allogeneic Hematopoietic Stem Cell Transplant (HSCT) for the Generation of Guidelines and Personalized Therapeutic Pathways (GITMO-RELAPSE)

Acute Myeloid Leukemia, in Relapse

Italy
University of Manitoba
Johns Hopkins University; University Health Network, Toronto; University of California... and other collaborators

Recruiting

International Milk Composition (IMiC) Consortium (IMiC)

Maternal Health | Infant Growth | Infant Nutrition

Canada
Regeneron Pharmaceuticals

Recruiting

Study for Desensitization of Chronic Kidney Disease in Adult Patients in Need of a Kidney Transplant Who Are Highly Sensitized to Human Leukocyte Antigen

Chronic Kidney Disease (CKD)

United States
Nanjing IASO Biotherapeutics Co.,Ltd

Not yet recruiting

A Phase 1/2 Study of CT120 in Patient With Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma

B-cell Non-Hodgkin's Lymphoma
Mahidol University
Ministry of Health, Thailand; Bhumirajanagarindra Kidney Institute, Thailand

Recruiting

Efficacy of Different Doses of Influenza Vaccine in Chronic Hemodialysis Patients (Enhance)

ESRD | Influenza Vaccine | Seroprotection

Thailand
National Cancer Institute (NCI)

Recruiting

T Cell Receptor Gene Therapy Targeting KK-LC-1 for Gastric, Breast, Cervical, Lung and Other KK-LC-1 Positive Epithelial Cancers

Kita-kyushu Lung Cancer Antigen 1, Human

United States
Central Hospital, Nancy, France

Not yet recruiting

Evaluation of Intradermal Hepatitis B Vaccine After IMIQUIMOD's Application, in Cirrhotics Who Did Not Respond to the Usual Vaccine Regimen (IDMODVHB)

Vaccine Reaction | HBV | Cirrhosis, Liver | Vaccination Failure
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Characterization of Tissue-Specific Immune Responses to Bronchoscopic Instillation of Mycobacterial Antigens Into the Human Lung

Healthy | Latent Tuberculosis Infection (LTBI)

United States
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; PPD; Rho Federal Systems Division, Inc.; Immune Tolerance...

Recruiting

Carfilzomib and Belatacept for Desensitization (ADAPT)

Highly Sensitized Prospective Kidney Transplant Recipients

United States
Diamyd Medical AB

Recruiting

A Phase III Study to Investigate if the Study Drug Diamyd Can Preserve Insulin Production and Improve Glycemic Control in Patients Newly Diagnosed With Type 1 Diabetes (DIAGNODE-3)

Type 1 Diabetes Mellitus

Czechia, Spain, United States, Hungary, Netherlands, Estonia, Germany, Poland, Sweden
Viracta Therapeutics, Inc.

Recruiting

An Open-Label, Phase 2 Trial of Nanatinostat in Combination With Valganciclovir in Patients With Epstein-Barr Virus-Positive (EBV+) Relapsed/Refractory Lymphomas (NAVAL-1)

EBV Related Non-Hodgkin's Lymphoma | Epstein-Barr Virus Associated Lymphoproliferative Disorder | EBV-Related PTLD | EBV Associated Lymphoma | EBV-Positive DLBCL, NOS | EBV Related PTCL, NOS

United States, Spain, Italy, United Kingdom, Singapore, Taiwan, Korea, Republic of, Germany, Canada, Brazil, Australia, France, Malaysia, Hong Kong, Israel
M.D. Anderson Cancer Center

Recruiting

Rituximab, Lenalidomide, Acalabrutinib, Tafasitamab Alone and With Combination Chemotherapy for the Treatment of Newly Diagnosed Non-germinal Center Diffuse Large B-Cell Lymphoma, Smart Stop Study

Diffuse Large B-Cell Lymphoma

United States
Beckman Coulter, Inc.

Recruiting

Access HBV Assays - European Union (EU) Clinical Trial Protocol -

HBV

France
Nantes University Hospital
Roche Diagnostics

Recruiting

HE4 in the Diagnostic Approach of Endometrial Cancer in Patients With Postmenopausal Bleeding (METRODEC)

Endometrial Neoplasms | Uterine Hemorrhage | Postmenopause | Cancer Biomarker | CA 125 Antigen

France
Crescendo Biologics Ltd.

Recruiting

Study of CB307 in Patients With Advanced and/or Metastatic PSMA-positive Tumours. (POTENTIA)

Advanced and/or Metastatic Solid Tumours

Spain, United Kingdom, Netherlands, United States
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; PPD; Rho Federal Systems Division, Inc.; Immune Tolerance...

Recruiting

Daratumumab and Belatacept for Desensitization (ATTAIN)

Highly Sensitized Prospective Kidney Transplant Recipients

United States
Wuhan Union Hospital, China
Chengdu USino Technology Biology Co., Ltd

Recruiting

Universal Chimeric Antigen Receptor-modified AT19 Cells for CD19+ Relapsed/Refractory Hematological Malignancies

B-cell Lymphoma | Acute Lymphoblastic Leukemia | Chronic Lymphoblastic Leukemia

China
Miltenyi Biomedicine GmbH

Recruiting

DALY II USA/ MB-CART2019.1 for DLBCL

Central Nervous System Lymphoma | Transformed Lymphoma | Refractory Diffuse Large B Cell Lymphoma (DLBCL) | Primary Mediastinal B-cell Lymphoma (PMBCL) | High Grade B-cell Lymphoma (HGBCL) | Relapsed Diffuse Large B Cell Lymphoma

United States
Adicet Bio, Inc

Recruiting

A Phase 1 Study of ADI-001 in B Cell Malignancies (GLEAN-1)

Lymphoma, Follicular | Lymphoma, Non-Hodgkin | Lymphoma, Mantle-Cell | Marginal Zone Lymphoma | Diffuse Large B Cell Lymphoma | Primary Mediastinal B-cell Lymphoma

United States
Benjamin Tomlinson

Recruiting

Human AntiCD19 Chimeric Antigen Receptor T Cells for Relapsed or Refractory Lymphoid Malignancies

Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Non Hodgkin Lymphoma

United States
Baylor College of Medicine
Center for Cell and Gene Therapy, Baylor College of Medicine

Not yet recruiting

Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

Liposarcoma | Liver Cancer | Rhabdomyosarcoma | Wilms Tumor | Malignant Rhabdoid Tumor | Yolk Sac Tumor

United States
UNC Lineberger Comprehensive Cancer Center
National Institutes of Health (NIH)

Recruiting

Phase I Study of Autologous CAR T-Cells Targeting the B7-H3 Antigen in Recurrent Epithelial Ovarian

Epithelial Ovarian Cancer

United States
Tongji Hospital
Nanjing IASO Biotechnology Co., Ltd.

Recruiting

Safety and Efficacy of CT103A Cells for Relapsed/Refractory Antibody-associated Inflammatory Diseases of the Nervous System (CARTinNS)

Multiple Sclerosis | Autoimmune Diseases of the Nervous System | Autoimmune Diseases | Myasthenia Gravis | Neuromyelitis Optica Spectrum Disorder | Autoimmune Encephalitis | Idiopathic Inflammatory Myopathies | Chronic Inflammatory Demyelinating Polyradiculoneuropathy | Myelin Oligodendrocyte Glycoprotein... and other conditions

China
Beijing Boren Hospital

Recruiting

Study of Anti-CD22 CAR-T Cells Treating Leukemia Children

Acute Lymphoblastic Leukemia | Acute Lymphoblastic Leukemia, in Relapse | Refractory Acute Lymphoblastic Leukemia

China
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Study of Kappa Chimeric Antigen Receptor (CAR) T Lymphocytes Co-Expressing the Kappa and CD28 CARs for Relapsed/Refractory Kappa+ Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.

Follicular Lymphoma | Splenic Marginal Zone Lymphoma | Mantle Cell Lymphoma | Indolent Non-hodgkin Lymphoma | Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue | Nodal Marginal Zone Lymphoma

United States
The University of Hong Kong

Recruiting

Detecting Occult HBV Infection in Liver Donors Positive for Antibody to Hepatitis B Core Antigen (Anti-HBc) (OBI)

Liver Transplant; Complications | Occult Hepatitis B

Hong Kong
Emory University

Recruiting

Early Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell Transplantation

Sickle Cell Disease

United States, Canada
Wuhan Sian Medical Technology Co., Ltd
Wuhan Union Hospital, China; Xiangyang Central Hospital; Jingzhou Central Hospital and other collaborators

Recruiting

Humanized CD19 Chimeric Antigen Receptor (CAR)-Modified T Cell Therapy in Treating Patients With B-cell Malignancies

B Cell Lymphoma | Acute Lymphoblastic Leukemia

China
Jonsson Comprehensive Cancer Center
Parker Institute for Cancer Immunotherapy

Recruiting

Modified Immune Cells (CD19/CD20 CAR-T Cells) in Treating Patients With Recurrent or Refractory B-Cell Lymphoma or Chronic Lymphocytic Leukemia

Recurrent Mantle Cell Lymphoma | Recurrent Small Lymphocytic Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Chronic Lymphocytic Leukemia | CD20 Positive | Refractory Mantle Cell Lymphoma | Recurrent Chronic Lymphocytic Leukemia | Refractory... and other conditions

United States
National Cancer Institute (NCI)
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

Optimizing PTCy Dose and Timing

Hematologic Neoplasms | Graft Versus Host Disease

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Re-evaluation of Donor-specific Anti-HLA Alloantibodies Immunoassay After Organ Transplantation, From Antigen Level to Epitope Level (ACORG-HLA)

Organ Transplantation
Hannover Medical School

Recruiting

Monitoring of Donor-specific Antibodies After Treatment With Immunoglobulins, Plasmapheresis and Rituximab in Lung Transplantation

Lung Transplantation | Donor-specific Anti-human Leukocyte Antigen(HLA) Antibodies

Germany
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Ipilimumab, Nivolumab, and Radiation Therapy in Treating Patients With HPV Positive Advanced Oropharyngeal Squamous Cell Carcinoma

Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7 | Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma... and other conditions

United States
UNC Lineberger Comprehensive Cancer Center
United States Department of Defense; Bellicum Pharmaceuticals; University Cancer...

Recruiting

Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/Refractory Osteosarcoma

Osteosarcoma | Neuroblastoma

United States
Hospital for Special Surgery, New York
Children's Healthcare of Atlanta; Campbell Clinic; Pediatric Orthopaedic Society... and other collaborators

Recruiting

Alpha-Defensin and Synovial Proteins to Improve Detection of Pediatric Septic Arthritis

Septic Arthritis | Joint Infection | Infection of Hip Joint (Disorder) | Infection of Shoulder Joint

United States
National Cancer Institute (NCI)

Recruiting

Testing the Addition of an Individualized Vaccine to Nab-Paclitaxel, Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Invasive Breast Carcinoma | Metastatic Triple-Negative Breast Carcinoma

United States
Medeor Therapeutics, Inc.

Not yet recruiting

Cellular Immunotherapy in Recipients of Human Leukocyte Antigen (HLA)-Mismatched, Living Donor Kidney Transplants

Kidney Transplant Rejection
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb

Recruiting

Trial of Nivolumab Following Partially Human Leukocyte Antigen (HLA) Mismatched BMT in Children & Adults With Sarcoma

Sarcoma | Solid Tumor, Adult | Solid Tumor, Childhood

United States
University of Erlangen-Nürnberg Medical School

Recruiting

Effect of Antigens or Therapeutic Agents on in Vitro Human Intestinal Organoids

Intestine Disease

Germany
Humanity and Health Research Centre
Beijing 302 Hospital

Recruiting

Performance of Scoring Systems in Chinese Patients With Primary Biliary Cholangitis (PBC) on Ursodeoxycholic Acid

Primary Biliary Cholangitis (PBC)

China
The First Hospital of Jilin University

Not yet recruiting

The Effect of Human Leukocyte Antigen Macthing on Guiding Tacrolimus Regimen After Liver Transplantation

Liver Transplantation | Drug-Related Side Effects and Adverse Reactions | Graft Rejection | Graft Versus Host Disease
UNC Lineberger Comprehensive Cancer Center
The Leukemia and Lymphoma Society; Bellicum Pharmaceuticals

Recruiting

Administration of Autologous CAR-T CD19 Antigen With Inducible Safety Switch in Patients With Relapsed/Refractory ALL

Immune System Diseases | Immunoproliferative Disorders | Acute Lymphoblastic Leukemia

United States

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