Search clinical trials for: Regulatory T Cells (Tregs)

Total 494992 results

Stanford University
University of California, San Francisco

Not yet recruiting

Islet Transplantation With Recipient T-Reg Cells or Deceased Donor Vertebral Bone Marrow Therapy

Islet Transplantation

United States
Centre Hospitalier Universitaire de Besancon

Recruiting

Interest of Follicular Helper Lymphocytes / Regulatory Follicular Helper Lymphocytes Ratio in IgA Nephropathy (LYMFONI)

Glomerulonephritis, IGA

France
Cellenkos, Inc.

Recruiting

Regulatory T Cells for Amyotrophic Lateral Sclerosis (REGALS)

Amyotrophic Lateral Sclerosis

United States
National Taiwan University Hospital

Recruiting

UVB-induced Treg Cells Exert Antigen-specific Suppression Through LAG-3

Psoriasis | Atopic Dermatitis

Taiwan
Ain Shams University

Not yet recruiting

Autologous Adoptive T Regulatory Cell Transfer in Autoimmune Diseases.

Type 1 Diabetes Mellitus | Lupus Nephritis

Egypt
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

In Vitro Effect Study of Interleukin-2 Muteins on Regulatory T Cells of Patients With Different Autoimmune, Allo-immune or Inflammatory Diseases (MuTreg)

Multiple Sclerosis | Autoimmune Diseases | Rheumatoid Arthritis | Systemic Lupus Erythematosus | Atopic Dermatitis | Vitiligo | Alopecia | Autoimmune Thyroiditis | Inflammatory Disease | Acquired Bone Marrow Aplasia | Gvhd
Centre Hospitalier St Anne
For Drug Consulting

Recruiting

Therapeutic Evaluation of Low-dose IL-2-based Immunomodulatory Approach in Patients With Early AD (IL-2-AD)

Alzheimer Disease

France
Cellenkos, Inc.

Recruiting

Leading in MPNs Beyond Ruxolitinib in Combo With T-Regs (TREG108)

Myelofibrosis

United States
Bacchetta, Rosa, MD
Food and Drug Administration (FDA); California Institute for Regenerative Medicine...

Recruiting

CD4^LVFOXP3 in Participants With IPEX

IPEX

United States
Quell Therapeutics Limited

Recruiting

Safety and Clinical Activity of QEL-001 in A2-mismatch Liver Transplant Patients (LIBERATE)

Liver Diseases | Liver Failure | Rejection; Transplant, Liver

Belgium, United Kingdom, Spain
Assistance Publique - Hôpitaux de Paris
Iltoo Pharma

Recruiting

Ciclosporin Followed by Low-dose IL-2 in Patients With Recently Diagnosed Type 1 Diabetes (DF-IL2-REP)

Type 1 Diabetes

France
Rapa Therapeutics LLC

Recruiting

RAPA-201 Therapy of Solid Tumors

Breast Cancer | Head and Neck Cancer | Gastric Cancer | Solid Tumor | Bladder Cancer | Triple Negative Breast Cancer | Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Malignant Melanoma | Carcinoma of Unknown Primary | Squamous Cell Carcinoma of Larynx | Squamous Cell Carcinoma of Oral Cavity | Squamous Cell Carcinoma of Nasopharynx and other conditions

United States
Masonic Cancer Center, University of Minnesota

Not yet recruiting

Ph I/II Study of CAR19 Regulatory T Cells (CAR19-tTreg) for R/R CD19+ B-ALL

Lymphoma Leukemia

United States
Fundación Pública Andaluza para la gestión de la...

Recruiting

Donor Regulatory T-cells for cGVHD in Patients Who do Not Obtain Complete Remission With Ruxolitinib (Treg4GVHD)

Chronic Graft vs Host Disease

Spain
Stanford University
Orca Biosystems, Inc.

Recruiting

Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft

Myelodysplastic Syndromes | Myeloproliferative Disorders | Acute Leukemia | Chronic Myelogenous Leukemia | Allogeneic Hematopoietic Cell Transplantation (HCT) | Advanced Hematologic Malignancies

United States
VTBIO Co. LTD

Recruiting

A Study of Possibility of Using Regulatory T Cells(VT301) for Treatment of Alzheimer's Disease

Alzheimer Disease

Korea, Republic of
Nantes University Hospital

Recruiting

Cellules B et Microbiote Dans le SNI

Microbiota | Glomerulosclerosis | B-lymphocytes | T-lymphocytes

France
Rafael Correa-Rocha
Instituto de Salud Carlos III; Fundación Familia Alonso

Recruiting

Cell Therapy With Treg Cells Obtained From Thymic Tissue (thyTreg) to Prevent Rejection in Heart Transplant Children (THYTECH)

Heart Transplantation

Spain
National Cancer Institute, Naples

Recruiting

PRELUDE-1 (Prospective Evaluation of Radiotherapy-induced Biologic Effects in Colorectal Cancer Oligometastatic Patients With LUng-limited Disease: Evolution of Cancer Genetics and Regulatory Immune Cells) (PRELUDE-1)

Colorectal Cancer Metastatic

Italy
Assiut University

Not yet recruiting

The Significance of Release of T-follicular Helper and T-follicular Regulatory Cells in Autoimmune Haemolytic Anemia Before and After Tratment (fhfr)

Autoimmune Hemolytic Anemia
Assiut University

Recruiting

Role of Regulatory B Cells in the Pathogenesis of Metabolic Associated Fatty Liver Disease

Non-Alcoholic Fatty Liver Disease

Egypt
Xuanwu Hospital, Beijing

Not yet recruiting

PD-L1-expressing Regulatory T Cells in Localized Prostate Cancer Patients Undergoing Iodine-125 Permanent Brachytherapy

Prostate Cancer
Boston Children's Hospital
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Recruiting

Low Dose IL-2 for the Treatment of Crohn's Disease

Crohn Disease

United States
Rapa Therapeutics LLC
Massachusetts General Hospital; Hackensack Meridian Health

Recruiting

RAPA-501 Therapy for ALS

Amyotrophic Lateral Sclerosis

United States
Amsterdam UMC, location VUmc

Recruiting

Function and Composition of Regulatory B Cells in Participants With Glioblastoma (GBMdexaB)

Glioblastoma, Adult

Netherlands
Wuerzburg University Hospital

Recruiting

Autologous Dendritic Cells, Metronomic Cyclophosphamide and Checkpoint Blockade in Children With Relapsed HGG

Childhood Glioblastoma

Germany
National Institute of Allergy and Infectious Diseases...
University of Pittsburgh

Recruiting

Allogeneic Regulatory Dendritic Cell (DCreg) Renal Study

Kidney Transplant | Renal Transplant Recipients

United States
BioDelivery Sciences International
HealthCore, Inc.

Recruiting

Risk of Major Adverse Cardiovascular Events for Naldemedine and Other Medications for Opioid Induced Constipation in Adults With Chronic Non-Cancer Pain

Opioid-induced Constipation

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Allogeneic Immunotherapy for Hematological Malignancies by Selective Depletion of Regulatory T Cells (DLI-Boost)

Hematological Malignancies | Relapse | Regulatory T Cell Depletion

France
Second Xiangya Hospital of Central South University

Recruiting

Safety and Efficacy of Umbilical Cord Blood Regulatory T Cells Plus Liraglutide on Autoimmune Diabetes

Type1 Diabetes Mellitus | Autoimmune Diabetes

China
Second Xiangya Hospital of Central South University

Recruiting

Safety Study and Therapeutic Effects of Umbilical Cord Blood Treg on Autoimmune Diabetes

Diabetes Mellitus, Type 1

China
Assistance Publique - Hôpitaux de Paris
Iltoo Pharma

Completed

Low-dose Interleukin-2 in Women With Unexplained Miscarriages (FaCIL-2)

Recurrent Miscarriage

France
Novartis Pharmaceuticals

Active, not recruiting

Study of Efficacy of CML-CP Patients Treated With ABL001 Versus Bosutinib, Previously Treated With 2 or More TKIs

Chronic Myelogenous Leukemia

United States, United Kingdom, Hungary, Japan, Saudi Arabia, Australia, Germany, Canada, France, Netherlands, Spain, Lebanon, Turkey, Korea, Republic of, Argentina, Brazil, Bulgaria, Czechia, Israel, Italy, Mexico, Romania, Russian... and more
Rapa Therapeutics LLC
Massachusetts General Hospital; Hackensack Meridian Health

Available

RAPA-501 Therapy for ALS EAP

Amyotrophic Lateral Sclerosis

United States
Sangamo Therapeutics

Enrolling by invitation

Long-Term Follow-Up of TX200-TR101 (STEADFAST Long Term)

End Stage Renal Disease | Kidney Transplant Rejection

Belgium, Netherlands, United Kingdom
Massachusetts General Hospital
Dana-Farber Cancer Institute; University of Regensburg

Completed

Infusion of T-Regulatory Cells in Kidney Transplant Recipients (The ONE Study)

Kidney Failure, Kidney Transplant

United States
AstraZeneca

Active, not recruiting

First Time in Human Study of AZD8701 With or Without Durvalumab in Participants With Advanced Solid Tumours

Melanoma | Cervical Cancer | Small Cell Lung Cancer | Triple Negative Breast Neoplasms | Advanced Solid Tumours | Non-Small-Cell Lung Cancer | Gastroesophageal Cancer | Clear Cell Renal Cell Cancer | Squamous Cell Cancer of Head and Neck

United States, Spain, Canada, France
Northwestern University

Active, not recruiting

Erythropoietin Therapy to Induce Regulatory T Cells in Liver Transplant Recipients

Liver Transplant Rejection

United States
University of North Carolina, Chapel Hill
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Suspended

Tailoring Maintenance Therapy to Cluster of Differentiation 5 Positive (CD5+) Regulatory B Cell Recovery in ANCA Vasculitis

ANCA Associated Vasculitis

United States
Everett Meyer
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Phase 1-2 MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T Cell

Lymphoma, Non-Hodgkin | Acute Myeloid Leukemia | Acute Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Myelodysplastic Syndromes (MDS) | Acute Lymphoblastic Leukemia (ALL) | Myeloid Leukemia, Chronic | Myeloproliferative Syndrome

United States
Centre Hospitalier Universitaire Dijon

Completed

Maternal Plasmatic Regulatory T Cells and Th17 as Possible Diagnosis Markers of Acute Chorioamnionitis (ICAR)

Pathology of Pregnancy

France
National Institute of Allergy and Infectious Diseases...
Rho Federal Systems Division, Inc.; Autoimmunity Centers of Excellence

Terminated

Polyclonal Regulatory T Cells (PolyTregs) for Pemphigus

Pemphigus Vulgaris | Pemphigus Foliaceus

United States
Novartis Pharmaceuticals

Available

CTL019 Out of Specification MAP for ALL or DLBCL Patients

Acute Lymphoblastic Leukemia (ALL) | Diffuse Large B-cell Lymphoma (DLBCL)

United States, Canada, Australia
Dana-Farber Cancer Institute
National Cancer Institute (NCI); Prometheus Laboratories; Miltenyi Biomedicine...

Active, not recruiting

Trial of Regulatory T-cells Plus Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-versus-Host-Disease

Chronic Graft Versus Host Disease | Chronic GVHD | Complications of Organ Transplant Stem Cells

United States
Al-Azhar University

Completed

Regulatory T Cell With Related Interleukins in Periodontal Disease Progression

Periodontitis | Gingivitis

Egypt
Aarhus University Hospital

Active, not recruiting

Residual Disease MEMory in PSOriasis Skin During EnstiLAR® and Narrow-band Ultraviolet B Therapy: The MEMPSOLAR Study (MEMPSOLAR)

Skin Diseases | Psoriasis | Skin Diseases, Papulosquamous | Psoriasis Vulgaris | Skin and Connective Tissue Diseases

Denmark
National Institute of Allergy and Infectious Diseases...

Withdrawn

Safety and Efficacy of Abatacept for Treating Chronic Cytopenia in Cytotoxic T-Lymphocyte Antigen 4 (CTLA4) Haploinsufficiency

CTLA4 Haploinsufficency | Chronic Cytopenia

United States
Everett Meyer
National Cancer Institute (NCI)

Withdrawn

Donor Regulatory T Cells in Treating Patients With Visceral Acute Graft-versus-Host Disease After Stem Cell Transplant

Graft Versus Host Disease

United States
Nektar Therapeutics
Eli Lilly and Company

Completed

A Study of NKTR-358 (LY3471851) in Participants With Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus

United States
Thomas Wekerle
University Hospital Regensburg

Active, not recruiting

Cell Therapy for Immunomodulation in Kidney Transplantation

Kidney Transplantation

Austria

Search clinical trials for: Regulatory T Cells (Tregs)

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