Search clinical trials for: Targeted Biopsy

Total 6145 results

Albany Medical College

Recruiting

Prostate Biopsy, Transrectal vs. Transperineal: Efficacy and Complications (ProBE-PC)

Prostate Cancer | Infection | PSA

United States
Dr. Nicola Schieda
The Ottawa Hospital Academic Medical Association

Recruiting

Comparison of a Novel Transperineal Targeted Fusion Biopsy System to Conventional Transrectal Targeted Fusion Biopsy

Prostate Cancer

Canada
Technical University of Munich

Recruiting

Liquid Biopsy-based Detection of Resistance to Targeted Therapy in Prostate Cancer Patients (PEARL)

Castration-resistant Prostate Cancer

Germany
National Cancer Institute (NCI)

Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

Malignant Glioma | Rhabdoid Tumor | Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Ependymoma | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Solid Neoplasm | Recurrent... and other conditions

United States, Puerto Rico, Australia, Canada
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust; University of Oxford; Queen Mary University... and other collaborators

Recruiting

The PROFILE Study: Germline Genetic Profiling: Correlation With Targeted Prostate Cancer Screening and Treatment (PROFILE)

Prostate Cancer | Genetic Counselling | Genetic Markers | Prostate Biopsy

United Kingdom
Yale University

Recruiting

MR-US Image Fusion Targeted Biopsy for Single-cell Prostate Cancer Research

Prostate Cancer

United States
Breast International Group
Jules Bordet Institute; Frontier Science & Technology Research Foundation,...

Recruiting

AURORA: Aiming to Understand the Molecular Aberrations in Metastatic Breast Cancer. (AURORA)

Metastatic Breast Cancer

Belgium, Spain, Portugal, United Kingdom, Italy, Germany, Iceland, Luxembourg, Sweden, Switzerland
National Cancer Institute (NCI)

Active, not recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Glioma | Hematopoietic and Lymphoid Cell Neoplasm | Melanoma | Lymphoma | Multiple Myeloma | Recurrent Ovarian Carcinoma | Breast Carcinoma | Recurrent Head and Neck Carcinoma | Recurrent Lung Carcinoma | Recurrent Skin Carcinoma | Gastric Carcinoma | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory... and other conditions

United States, Puerto Rico, Guam
Weill Medical College of Cornell University
National Cancer Institute (NCI)

Completed

PReclude Infection EVEnts With No Prophylaxis Transperineal Biopsy (PREVENT)

Infection

United States
Paris Translational Research Center for Organ Transplantation
University of Padova; Cedars Sinai Medical Center, Los Angeles, USA

Completed

Molecular Diagnosis of Heart Allograft Rejection Using Intra-Graft Targeted Gene Expression Profiling. (Nano-Heart)

Heart Transplant Rejection

United States, France, Italy
National Cancer Institute (NCI)

Active, not recruiting

Testing Copanlisib as a Potential Targeted Treatment in Cancers With PIK3CA Mutations (MATCH-Subprotocol Z1F)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma | Hematopoietic and Lymphatic System Neoplasm

United States
National Cancer Institute (NCI)

Withdrawn

Adding Targeted Drugs to Usual Chemotherapy for Adults With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LBL)

T Acute Lymphoblastic Leukemia | T Lymphoblastic Lymphoma
National Cancer Institute (NCI)

Suspended

Testing a New Immune Cell Therapy, GD2-Targeted Modified T-cells (GD2CART), in Children, Adolescents, and Young Adults With Relapsed/Refractory Osteosarcoma and Neuroblastoma, The GD2-CAR PERSIST Trial

Recurrent Neuroblastoma | Recurrent Osteosarcoma | Refractory Neuroblastoma | Refractory Osteosarcoma

United States
M.D. Anderson Cancer Center

Active, not recruiting

Erdafitinib for the Treatment of Patients With Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Bone | Stage IVA Prostate Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8 | Metastatic Prostate Small Cell Neuroendocrine Carcinoma | Metastatic Prostate Adenocarcinoma | Castration-Resistant...

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing Ipatasertib as Potentially Targeted Treatment in Cancers With AKT Genetic Changes (MATCH - Subprotocol Z1K)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing LOXO-101 as Potentially Targeted Treatment in Cancers With NTRK Genetic Changes (MATCH - Subprotocol Z1E)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing MLN0128 (TAK-228) as Potentially Targeted Treatment in Cancers With TSC1 or TSC2 Genetic Changes (MATCH - Subprotocol M)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing BVD-523FB (Ulixertinib) as Potentially Targeted Treatment in Cancers With Genetic Changes (MATCH - Subprotocol Z1L)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing Sunitinib as Potentially Targeted Treatment in Cancers With cKIT Genetic Changes (MATCH - Subprotocol V)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing Afatinib as Potentially Targeted Treatment in Cancers With EGFR Genetic Changes (MATCH - Subprotocol A)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing MLN0128 (TAK-228) as Potentially Targeted Treatment in Cancers With mTOR Genetic Changes (MATCH - Subprotocol L)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma

United States
Henry Ford Health System
M.D. Anderson Cancer Center

Completed

Determining the Tolerance of Depigmented Skin to Targeted Phototherapy Using UVB in Patients With Vitiligo

Vitiligo

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing Crizotinib as Potentially Targeted Treatment in Cancers With MET Exon 14 Deletion Genetic Changes (MATCH - Subprotocol C2)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing Crizotinib as Potentially Targeted Treatment in Cancers With MET Genetic Changes (MATCH - Subprotocol C1)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing GDC-0449 (Vismodegib) as Potentially Targeted Treatment in Cancers With Smoothened or Patched 1 Mutant Tumors (MATCH - Subprotocol T)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma | Hematopoietic and Lymphatic System Neoplasm

United States
Princess Al-Johara Al-Ibrahim Cancer Research Center

Completed

Randomized Controlled Trial of MRI Target Biopsy: Transrectal vs. Transperineal

Prostate Cancer

Saudi Arabia
National Cancer Institute (NCI)

Active, not recruiting

Testing AZD9291 as Potentially Targeted Treatment in Cancers With EGFR Genetic Changes (MATCH-Subprotocol E)

Hematopoietic and Lymphoid Cell Neoplasm | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma
OHSU Knight Cancer Institute
Oregon Health and Science University; U.S. National Science Foundation

Suspended

Feasibility of OmnEcoil System for Integrated Endorectal MRI and Transrectal MRI-Targeted Biopsy of the Prostate

Prostate Carcinoma

United States
Institut Curie

Active, not recruiting

SHIVA02 - Evaluation of the Efficacy of Targeted Therapy Based on Tumor Molecular Profiling in Patients With Advanced Cancer Using Each Patient as Its Own Control (SHIVA02) (SHIVA02)

Cancer | Solid Tumor, Adult

France
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Molecular Mechanisms of Clinical Resistance to Targeted Therapy Among Patients With Breast Cancer

Breast Cancer

United States
Institute of Cancer Research, United Kingdom

Active, not recruiting

The BARCODE 1 Study (Full Study): The Use of Genetic Profiling to Guide Prostate Cancer Targeted Screening. (BARCODE1)

Prostate Cancer

United Kingdom
Duke University

Terminated

ARFI Imaging for Targeted Prostate Biopsy

Prostate Cancer

United States
Cliniques universitaires Saint-Luc- Université...

Active, not recruiting

Prospective Collection of Tumor Biopsy and Plasma Samples From Cancer Patients Treated With Molecular Targeted Therapies or Immunotherapy (Plasma-Target)

Cancer

Belgium
Gustave Roussy, Cancer Campus, Grand Paris

Active, not recruiting

A Prospective Trial to Study the Evolution of Clonal Architecture of Tumors From Patients Treated With Molecular Targeted Agents (MATCH-R)

Metastatic Oncogen-driven Cancer

France
The First Affiliated Hospital with Nanjing Medical...

Completed

Targeted Biopsy of Carbon Nanoparticles Labelled Axillary Node for cN+ Breast Cancer

Location and Biopsy of Axillary Lymph Nodes

China
Osamu Ukimura

Active, not recruiting

Targeted Cryoablation of Prostate Cancer Lesions: An Investigator-initiated Trial (PROCRY)

Prostate Cancer

Japan
University College, London
King's College London; Imperial College London; Medical Research Council; Cancer...

Active, not recruiting

ReIMAGINE Prostate Cancer Risk

Prostate Cancer

United Kingdom
Calithera Biosciences, Inc

Terminated

NGS Screening Protocol to Detect Mutation of KEAP1 or NRF2/NFE2L2 Genes for the KEAPSAKE (CX-839-014) Trial

Non-Small Cell Lung Cancer | Non-squamous Non-small-cell Lung Cancer | Non-Squamous Non-Small Cell Neoplasm of Lung | KEAP1 Gene Mutation | NFE2L2 Gene Mutation | NRF2 Mutation

United States
Netherlands Working Group on Immunotherapy of Oncology
Hoffmann-La Roche; Amsterdam UMC, location VUmc; The Netherlands Cancer Institute

Terminated

Vemurafenib Plus Cobimetinib in Metastatic Melanoma (REPOSIT)

Metastatic Melanoma

Netherlands
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Completed

A Prospective Study Of Free-Hand Transperineal Image Fusion Targeted Biopsies Under Local Anesthesia

Prostate Neoplasm

China
Radboud University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Culture-guided Antimicrobial Prophylaxis in Men Undergoing Prostate Biopsy. (pro-SWAP)

Prostate Cancer | Infection | Complication

Netherlands
NYU Langone Health

Terminated

Comparative Analysis of Transperineal Versus Transrectal Approaches for MRI-Targeted Biopsy of the Prostate for the Detection and Characterization of Prostate Cancer

Prostate Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); GlaxoSmithKline; Merck Sharp & Dohme LLC; Nova...

Completed

BATTLE-2 Program: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small Cell Lung Cancer

Lung Cancer

United States
Aarhus University Hospital
Karolinska University Hospital; Karolinska Institutet; University of Aarhus; Central... and other collaborators

Unknown

Early and Accurate Detection of Prostate Cancer in General Practice

Prostate Cancer | Prostate Adenocarcinoma | Prostate Neoplasm

Denmark
Exact Imaging

Completed

Urology San Antonio MRI/MicroUS Comparison

Prostate Cancer

United States
Kliniken Essen-Mitte
German Breast Group

Completed

Registry Trial to Evaluate the Clinical Utilization of Targeted Axillary Dissection (TAD)

Early Stage Breast Cancer

Germany
University Hospital, Montpellier

Completed

Prostate Biopsies With Target Lesion on MRI

Prostate Cancer

France
NYU Langone Health

Completed

PET/MRI Study of Men With Highly Suspicious MRI Lesions That Showed no Clinically Significant Prostate Cancer Following MRI Fusion Targeted Biopsy

Prostate Cancer

United States
Prof. Dr. med. Dirk Schadendorf

Terminated

Biopsy- and Biology-driven Optimization of Targeted Therapy in Subjects With Advanced Melanoma (BOTTOM)

Malignant Melanoma

Germany
The First Affiliated Hospital of Xiamen University

Unknown

Molecular Imaging Visualization of Tumor Heterogeneity in Non-small Cell Lung Cancer

NSCLC | Radiomics | Biopsy | Genomics | PET/CT | Whole-exome Sequencing

China

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