Search clinical trials for: Thalassemia major

Total 4710 results

Assiut University

Completed

Evaluation of Nutritional Status in Thalassemia Major Patients in Assiut Children Hospital

Thalassemia Major

Egypt
Ain Shams University

Completed

Congenital Heart Surgery in Pediatric Patients With Beta-Thalassemia Major

Hemolysis
Beni-Suef University

Completed

The Effect of N-acetylcysteine on Oxidative Stress Status and Iron Overload in Thalassemia Major

Thalassemia Major

Egypt
Ente Ospedaliero Ospedali Galliera
University of Campania "Luigi Vanvitelli"; Reggio Calabria; Ospedale Maggiore... and other collaborators

Completed

Efficacy and Safety of Neridronate (Nerixia®)to Treat Osteoporosis in Patients With TM and TI (Nerixia)

Osteoporosis | Thalassemia Major | Thalassemia Intermedia

Italy
Assiut University

Unknown

Complications in Children With B- Thalassemia Major

Beta-thalassemia
Emory University

Completed

Bone Marrow Transplant With Abatacept for Non-Malignant Diseases

Sickle Cell Disease | Fanconi Anemia | Hurler Syndrome | Chronic Granulomatous Disease | Severe Congenital Neutropenia | Hemophagocytic Lymphohistiocytosis | Wiskott-Aldrich Syndrome | Diamond-Blackfan Anemia | Severe Aplastic Anemia | Glanzmann Thrombasthenia | Shwachman-Diamond Syndrome | Thalassemia Major | Leukocyte... and other conditions

United States
National Human Genome Research Institute (NHGRI)

Completed

Perceptions of Thalassemia Major in Singapore: An Exploratory Study of Stigma

Thalassemia Major

Singapore
Hamad Medical Corporation

Terminated

Denosumab Versus Zoledronic Acid in Thalassemia-Induced Osteoporosis (DOHA)

Osteoporosis | Thalassemia Majors (Beta-Thalassemia Major)

Qatar
HaEmek Medical Center, Israel

Completed

Endocrine and Nutritional Assessment in B Thalassemia Major

Thalassemia

Israel
Assiut University

Completed

Erythrocyte Glutamine Level Relation to Pulmonary Hypertension Risk in Beta Thalassemia Major Children

Hemolysis | Pulmonary Hypertension | Thalassemia in Children

Egypt
Ersi Voskaridou

Completed

Denosumab vs Placebo in Patients With Thalassemia Major and Osteoporosis

Osteoporosis | Thalassemia Major

Greece
Indonesia University

Completed

The Effect of Alpha-tocopherol in Hemolysis and Oxidative Stress Marker on the Red Cell Membrane Beta-thalassemia Major

Hemolysis | Oxidative Stress | Beta Thalassemia Major Anemia

Indonesia
Aga Khan University

Completed

Anthropometric Measurements in Children Having Transfusion-dependent Beta Thalassemia

Beta Thalassemia Major
bluebird bio

Completed

A Study Evaluating the Safety and Efficacy of the LentiGlobin BB305 Drug Product in β-Thalassemia Major Participants

β-thalassemia Major

United States, Australia, Thailand
Tanta University

Completed

Effect of Spirulina on Serum Hyaluronic Acid in Beta Thalassemic Children With Hepatitis C

Beta Thalassemia Major

Egypt
Assiut University

Unknown

Dermatological Abnormalities in Beta-thalassemia Major

Beta-Thalassemia
Children's Hospital of Philadelphia
Ann & Robert H Lurie Children's Hospital of Chicago; The Cooley's Anemia Foundation...

Completed

Combination Deferasirox and Deferiprone for Severe Iron Overload in Thalassemia

Thalassemia Major With Severe Transfusional Iron Overload

United States
Ain Shams University

Completed

Zinc Supplementation in Patients With β-Thalassemia Major Complicated With Diabetes Mellitus

Beta-thalassemia Major Complicated With Diabetes

Egypt
Assiut University

Unknown

Sexual Maturation in β-Thalassemia Major Patients in Assiut University Hospital

β-Thalassemia Major Patients Receiving Chelation Therapy
Tanta University

Completed

Effects of Spirulina on Cardiac Functions in Children With Beta Thalassemia Major

Beta Thalassemia

Egypt
Tanta University

Completed

Effect of Spirulina on Liver Iron Concentration in Beta Thalassemic Children With Hepatitis C

Beta Thalassemia Major

Egypt
Tanta University

Completed

Effect of Spirulina on Liver Fibrosis by Transient Elastography in Beta Thalassemic Children With Hepatitis C

Beta Thalassemia Major

Egypt
First Affiliated Hospital of Guangxi Medical University

Unknown

Monitoring of Chimerism After Transplantation in Patients With β Thalassemia Major and the Treatment Strategies for the Reduction of Chimerism

Beta Thalassemia Major

China
Cerus Corporation

Completed

Study to Evaluate Efficacy and Safety of S303 Treated Red Blood Cells (RBCs)in Subjects With Thalassemia Major Requiring Chronic RBC Transfusion

Thalassemia Major

Turkey, Italy
Cairo University

Unknown

The Potential Hepatoprotective Effect of Metformin in Patients With Beta Thalassemia Major

Beta Thalassemia Major Anemia

Egypt
Tanta University

Completed

Effect of Spirulina Compared to Amlodipine on Cardiac Iron Overload in Children With Beta Thalassemia

Beta Thalassemia Major

Egypt
Assistance Publique - Hôpitaux de Paris

Completed

Assessment of Tolerance of Mobilizing Peripheral Hematopoietic Stem Cells by Plerixafor in Sickle Cell Patients (DrepaMob)

Major Sickle Cell Syndrome of Type SS or Sβ Thalassemia

France
Tanta University

Completed

the Potential Immunomodulatory Effects of Spirulina on Thalassemic Children

Beta Thalassemia Major

Egypt
King Saud University

Completed

Periodontal Therapy in Thalassemia Major Patients

Chronic Periodontitis | Thalassemia Major
Nanfang Hospital of Southern Medical University
Guangdong Yike Gene Science and Technology CO.,Ltd

Unknown

Gene Therapy for Beta-Thalassemia Major Using Autologous Hematopoietic Stem Cell Genetically Modified

Beta Thalassemia Major

China
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of INC424 in Regularly Transfused Patients With Thalassemia.

Thalassemia Major

Thailand, Turkey, Italy, Lebanon, Greece
First Affiliated Hospital of Guangxi Medical University

Unknown

Haploidentical Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major

Thalassemia Major

China
Tanta University

Unknown

Benefits of Nigella Sativa in Children With Beta Thalassemia Major (Nigella)

Nigella Sativa With Beta Thalassemia Major

Egypt
Tanta University

Unknown

Study of The Therapeutic Benefits of Al-hijamah in Children With Beta Thalassemia Major (Al-hijamah)

AL-Hijama in Thalassmia Major

Egypt
Novartis Pharmaceuticals

Withdrawn

An Open Label Study to Evaluate the Pharmacokinetics, Safety, Tolerability and Efficacy of Deferasirox Administered to Chinese Patients With β-thalassemia Major Aged From 2 to Less Than 6 Years Old (MACS2163)

β-thalassemia Major
Assistance Publique - Hôpitaux de Paris
CNAMTS; AFDPHE; National reference center for thalassemia; National laboratories... and other collaborators

Completed

Quality of Care of Children With Sickle Cell Disease (SCD) Screened at Birth in France (EVADREP)

Sickle Cell Disease | New-borns Screening
Fakultas Kedokteran Universitas Indonesia

Completed

Zinc Supplementation on Cellular Immunity in Thalassemia Major

Thalassemia | Immunosuppression | Splenectomy; Status

Indonesia
Fakultas Kedokteran Universitas Indonesia

Completed

Pneumococcal Vaccination for Splenectomised Thalassemia Major Patients in Indonesia

Thalassemia | Pneumococcal Infection

Indonesia
Mahidol University

Completed

The Prevalence and Severity of HCV Infection in Thalassemia Major and Thalassemia Intermedia in Siriraj Hospital

Fibrosis | Hepatitis C | Thalassemia

Thailand
Novartis Pharmaceuticals

Completed

A 4-year Extension Study to Core 1-year Study of Iron Chelation Therapy With Deferasirox in β-thalassemia Major Pediatric Patients With Transfusional Iron Overload.

Transfusional Iron Overload | β-thalassemia Major | Pediatric Rare Anemia

Italy, France
Novartis

Completed

A Study of Long-term Treatment With Deferasirox in Patients With Beta-thalassemia and Transfusional Hemosiderosis

Beta-Thalassemia | Hemosiderosis

Egypt, Lebanon, Oman, Saudi Arabia, Syrian Arab Republic
Consorzio per Valutazioni Biologiche e Farmacologiche
European Commission

Completed

Pharmacokinetic Study of Deferiprone in Paediatric Patients (DEEP-1)

Chronic Iron Overload

Italy, Cyprus, Egypt
Ain Shams University

Unknown

Sperm DNA Damage in β-thalassemia Major: Is There a Role for Antioxidants?

DNA Damage | Endocrine Disease | Fertility Decreased Male

Egypt
Memorial Sloan Kettering Cancer Center

Completed

Assess the Feasibility and Safety of Granulocyte Colony Stimulating Factor (GCSF) Mobilization of CD34+ Hematopoietic Progenitor Cells in Patients With Betathalassemia Major

Beta Thalassemia Major | Congenital Anemias

United States
Novartis Pharmaceuticals

Completed

Post Hematopoietic Stem Cell Transplantation

Iron Overload After Hematopoietic Stem Cell Transplantation (HSCT) in Patients With Beta-thalassemia Major

Turkey
Columbia University

Completed

High-Tc Susceptometer to Monitor Transfusional Iron Overload

Myelodysplastic Syndromes | Sickle Cell Disease | Aplastic Anemia | Transfusional Iron Overload | Thalassemia Major

United States
University of British Columbia

Unknown

Utility of Fibroscan in Estimating Hepatic Iron Concentration

Hereditary Anemias

Canada
ApoPharma

Completed

Efficacy Study in Removing Excess Iron From the Heart

Hemosiderosis | Thalassemia Major

Greece, Italy
University of Campinas, Brazil
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Amlodipine in the Prevention and Treatment of Iron Overload in Patients With Thalassemia Major (AmloThal)

Iron Overload | Thalassemia

Brazil
HaEmek Medical Center, Israel

Completed

Iron Overload and Growth Velocity in Thalassemia and Sickle Cell Anemia

Sickle Cell Disease | Thalassemia

Israel

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