Search clinical trials for: brain death

Total 38342 results

Bayer

Active, not recruiting

Study to Evaluate the Efficacy (Effect on Disease) and Safety of Finerenone on Morbidity (Events Indicating Disease Worsening) & Mortality (Death Rate) in Participants With Heart Failure and Left Ventricular Ejection Fraction (Proportion of Blood Expelled Per Heart Stroke) Greater or Equal to 40% (FINEARTS-HF)

Heart Failure

United States, Spain, Denmark, Korea, Republic of, Taiwan, Australia, Hong Kong, Russian Federation, Israel, Canada, Malaysia, United Kingdom, Latvia, Netherlands, Japan, Brazil, China, Lithuania, Poland, Turkey, Italy, Austria, Bul... and more
Intermountain Health Care, Inc.

Active, not recruiting

A Trial Evaluating Vitamin D Normalization on Major Adverse Cardiovascular-Related Events Among Myocardial Infarction Patients (TARGET-D)

Myocardial Infarction | Death | Cerebral Vascular Accident | Heart Failure Hospitalization

United States
University Hospital Birmingham NHS Foundation Trust
Northern Care Alliance NHS Foundation Trust; Cambridge University Hospitals... and other collaborators

Active, not recruiting

Arrhythmia Burden, Risk of Sudden Cardiac Death and Stroke in Patients With Fabry Disease (RaILRoAD)

Fabry Disease

United Kingdom, Australia
Imperial College London

Active, not recruiting

Heart Beat Variability in Neonatal Encephalopathy (HeartBeat)

Hypoxic-Ischemic Encephalopathy | Neonatal Encephalopathy | Asphyxia Neonatorum

United Kingdom
Hospital de Clinicas de Porto Alegre

Completed

The Use of Liraglutide in Brain Death

Brain Death

Brazil
University of Toronto
Ottawa Hospital Research Institute; Sunnybrook Research Institute; ICES

Completed

Development and Validation of a Dementia Life Expectancy Tool

Death | Dementia
Eurasian Association of Therapists

Completed

Clinical Register Studying the therApeutic Patient Population With Multifocal Atherosclerosis (KAMMA)

Cardiovascular Diseases | Chronic Kidney Diseases | Atherosclerosis | Bleeding | Acute Coronary Syndrome | Cardiac Death | Acute Stroke | Polyvascular Disease | Atherosclerosis Generalized

Russian Federation
Cairo University

Completed

Autonomic Dysfunction in Temporal Lobe Epilepsy and SUDEP

Temporal Lobe Epilepsy

Egypt
Kiskunhalas Semmelweis Hospital the Teaching Hospital...
Szeged University; Budapest University of Technology and Economics; Hochschule...

Completed

Electrical Impedance Tomography Measurements During Apnea Test in Patients With Suspected Brain Death

Brain Death

Hungary
Canadian Network for Observational Drug Effect...
Canadian Institutes of Health Research (CIHR); Drug Safety and Effectiveness...

Completed

Domperidone and Risk of Sudden Cardiac Death

Parkinson's Disease

Canada
Canadian Network for Observational Drug Effect...
Canadian Institutes of Health Research (CIHR); Drug Safety and Effectiveness...

Completed

Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors and Risk of Cardiovascular Events

Myocardial Infarction | Heart Failure | Ischemic Stroke | Type2 Diabetes | Cardiovascular Death | All-Cause Mortality

Canada
Korgün Ökmen

Completed

Orbital Artery Doppler Ultrasound in Brain Death

Brain Death

Turkey
Liu Yonghong

Enrolling by invitation

Electroclinical Features of Sudden Unexpected Death in Epilepsy (SUDEP) : a Multi-center Observational Study

Sudden Unexpected Death in Epilepsy | Near-Sudden Unexpected Death in Epilepsy

China
Washington University School of Medicine
Mid-America Transplant

Completed

Intravenous Thyroxine for Heart-Eligible Organ Donors

Heart Failure | Brain Death

United States
Merck Sharp & Dohme LLC

Active, not recruiting

Substudy 02D: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With Melanoma Brain Metastasis (MK-3475-02D/KEYMAKER-U02)

Melanoma

Spain, United States, Australia, France, Israel, Italy, South Africa, Switzerland
Sheba Medical Center
Mayo Clinic

Active, not recruiting

Association of Endothelial Function and Clinical Outcomes in Subjects Admitted to Chest Pain Unit

Myocardial Infarction | Death | Angina Pectoris | Cerebrovascular Accident | Congestive Heart Failure

United States, Israel
Boehringer Ingelheim
Eli Lilly and Company

Completed

EMPACT-MI: A Study to Test Whether Empagliflozin Can Lower the Risk of Heart Failure and Death in People Who Had a Heart Attack (Myocardial Infarction)

Myocardial Infarction

United States, Spain, Australia, Denmark, Netherlands, Canada, China, Germany, Korea, Republic of, Israel, Hungary, Japan, Argentina, France, Romania, Russian Federation, Serbia, Ukraine, Poland, India, Brazil, Bulgaria
McGill University Health Centre/Research Institute...

Active, not recruiting

Sildenafil to Repair Brain Injury Secondary to Birth Asphyxia (SANE-02)

Birth Asphyxia

Canada
Medipol University

Completed

Effect of Non-nutritive Sucking on Transition to Oral Feeding in Infants With Asphyxia

Perinatal Asphyxia | Hypoxic-Ischemic Encephalopathy | Swallowing Disorder | Feeding; Difficult, Newborn | Speech Therapy | Feeding Disorder of Infancy or Early Childhood

Turkey
Xuanwu Hospital, Beijing

Completed

Research on the Brain Death Determination in China (RBDDC)

Brain Death | Electroencephalogram | Evoked Potential | TCD | Quality Control

China
Alexandria University

Completed

Passive Cooling Versus Blanket-Roll III on The Myocardial Function of Asphyxiated Neonates

Neonatal Encephalopathy | Birth Asphyxia | Hypothermia, Newborn | Hypoxic Encephalopathy

Egypt
Nemours Children's Clinic
Sharp HealthCare; NPKSIMS, Nagpur, India

Withdrawn

Umbilical Cord Milking in Neonates Who Are Depressed at Birth-Developmental Follow Up (MIDAB-FU) (MIDAB-FU)

Hypoxic-Ischemic Encephalopathy | Birth Asphyxia

India
Semmelweis University

Completed

Hydrocortisone Treatment In Systemic Low Blood Pressure During Hypothermia in Asphyxiated Newborns (CORTISoL)

Asphyxia | Hypoxic-Ischemic Encephalopathy

Hungary
Emory University
National Institute on Aging (NIA)

Completed

Preparation for End-of-Life Decision Making in Mild Dementia

Dementia

United States
University of California, San Francisco
Boston University; Johns Hopkins University; Children's Hospital of Philadelphia and other collaborators

Completed

High-dose Erythropoietin for Asphyxia and Encephalopathy (HEAL)

Neonatal Encephalopathy | Birth Asphyxia

United States
Rush University Medical Center
Icahn School of Medicine at Mount Sinai

Withdrawn

Telerobotic Ultrasound for Carotid Imaging - Feasibility Study

Myocardial Infarction | Myocardial Ischemia | Heart Diseases | Coronary Artery Disease | Stroke | Cerebrovascular Disorders | Coronary Disease | Arteriosclerosis | Arterial Occlusive Diseases | Cardiovascular Disease | Atherosclerosis | Peripheral Vascular Disease | Cerebral Infarction | Coronary Arteriosclerosis | Cerebrovascular... and other conditions
MemorialCare Health System

Completed

Does Venous pCO2 Increase by 20 mmHg or More During Apnea Challenge Test?

Brain Death

United States
University Hospital, Montpellier
Université Montpellier

Completed

Phenomenological Approach of Epilepsy in Patients With Epilepsy

Epilepsy

France
Nantes University Hospital
Ministry of Health, France

Completed

Therapeutic Hypothermia in "Expanded Criteria" Brain-dead Donors and Kidney-graft Function (HYPOREME)

Critical Illness | Hypothermia | Brain Death | Kidney Transplant; Complications | Organ Donor

France
University of California, San Francisco
Oregon Health and Science University

Completed

Deceased Organ Donor Interventions to Protect Kidney Graft Function

Brain Death | Organ Donation | Delayed Graft Function | Organ Transplant Failure or Rejection

United States
Imperial College London
University College London Hospitals; Guy's and St Thomas' NHS Foundation Trust

Completed

Neuroprotective Effects of Hypothermia Combined With Inhaled Xenon Following Perinatal Asphyxia (TOBYXe)

Hypoxic Ischaemic Encephalopathy

United Kingdom
Boston Scientific Corporation
ICON Clinical Research

Completed

Heart Failure and Sudden Cardiac Death Japan Registry (HINODE)

Heart Failure | Arrhythmias, Cardiac | Sudden Cardiac Death

Japan
Indiana University
Greenwich Biosciences; Child Neurology Foundation

Completed

Improving Patient Communication About SUDEP

Epilepsy | SUDEP

United States
Kahramanmaras Sutcu Imam University

Completed

Associations Between General Movements Assessments and Cognitive Development (GMs)

Cerebral Palsy | Infant, Premature, Diseases | Cognitive Dysfunction | Infant Development | Infant, Very Low Birth Weight | Infant, Small for Gestational Age | Infant Asphyxia | Cognitive Impairment, Mild | Cognitive Developmental Delay

Turkey
Kahramanmaras Sutcu Imam University

Completed

Associations Between Early Neonatal Neuroimaging, Hammersmith Infant Neurological Examination and General Movements (highrisk)

Cerebral Palsy | Infant, Premature, Diseases | Neurologic Disorder | Infant, Newborn, Disease | Infant Development | Development Delay | Infant, Very Low Birth Weight | Infant, Small for Gestational Age | Infant Asphyxia

Turkey
Poznan University of Medical Sciences

Completed

The Impact of Selected Factors on the Cardiovascular System in Chronic Kidney Disease

Cardiovascular Diseases | Inflammation | Chronic Kidney Diseases | Dialysis; Complications | Atherosclerosis of Artery

Poland
Gorm Greisen
Copenhagen Trial Unit, Center for Clinical Intervention Research; Elsass Foundation

Completed

Safeguarding the Brain of Our Smallest Infants Phase III (SafeBoosC)

Brain Injuries | Infant, Extremely Premature | Death; Neonatal | Death, Brain

Denmark
University of Thessaly

Completed

MACE and PE in Elective Primary TKA & THA

Stroke | Death | Transient Ischemic Attack | Pulmonary Embolism | Cardiovascular Complication

Greece
Aristotle University Of Thessaloniki
Papageorgiou General Hospital

Completed

Resting Energy Needs in Brain Dead Patients (reSting EneRgy nEeds iN brAin DEad Patients) (SERENADE)

Brain Injuries | Brain Death | Brain Edema | Brain Hemorrhage

Greece
Loma Linda University

Withdrawn

Maternal Hyperoxygenation for Intrapartum Fetal Heart Rate Tracing Abnormalities

Intracranial Hemorrhages | Respiratory Distress Syndrome, Newborn | Hypoxic-Ischemic Encephalopathy | Perinatal Death | Neonatal Seizure | Meconium Aspiration Syndrome | Neonatal Hypotension

United States
Prisma Health-Midlands

Withdrawn

Rapid Reversal of CNS-Depressant Drug Effect Prior to Brain Death Determination

Cardiac Arrest | Brain Death | Anoxic Brain Injury | Sedative Intoxication | Narcotic Intoxication

United States
Hospital Clinic of Barcelona

Completed

Controlled Donors After Circulatory Death and Brain Death: a Multicenter Study of Transfusion, One-year Graft Survival and Mortality. Cohort Study,

Liver Transplant

Spain
Hospital de Clinicas de Porto Alegre
Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul, Brazil

Suspended

Effect of Acetaminophen and N-Acetylcysteine on Liver Metabolism on Homocystinuria

CBS Deficiency

Brazil
Ting Li

Unknown

Circulation and Oxygenation Changes of Deep Tissue Respond on LLLT

Near Infrared Spectroscopy | Low Level Light/Laser Therapy

China
University Hospital, Basel, Switzerland

Completed

Brain Death Diagnosis at an Academic Tertiary Medical Care Center

Brain Death

Switzerland
Vanderbilt University Medical Center
University of California, Los Angeles; University of California, San Francisco and other collaborators

Terminated

Goal of Open Lung Ventilation in Donors (GOLD)

Brain Death | Organ Donation | Organ Transplant Failure or Rejection

United States
Semmelweis University

Completed

Hypoxic-Ischemic Encephalopathy Therapy Optimization in Neonates for Better Neuroprotection With Inhalative CO2 (HENRIC)

Perinatal Asphyxia | Hypocapnia | Hypoxic-Ischaemic Encephalopathy

Hungary
Sanko University

Completed

Turkish Validity And Reliability Of The Hammersmith Infant Neurological Evaluation (Hine) (Hine)

Cerebral Palsy | Infant, Premature, Diseases | Infant Development | Infant Asphyxia | Reliability | Validity

Turkey
Sanko University

Completed

Effectiveness of Family Collaborative Physiotherapy Programs With High-risk Infants

Cerebral Palsy | Infant, Premature, Diseases | Infant, Newborn, Disease | Infant Development | Infant, Very Low Birth Weight | Infant, Small for Gestational Age | Infant Asphyxia | Infant of Diabetic Mother

Turkey
University Hospital, Aachen

Completed

HOPE for Human Extended Criteria and Donation After Brain Death Donor (ECD-DBD) Liver Allografts (HOPE-ECD-DBD)

Liver Transplant | Hepatocellular Injury

Germany, Czechia

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