Search clinical trials for: fibrinolysis

Total 110 results

Bernd Jilma

Completed

Defibrotide in the Human Endotoxemia Model --- an Exploratory Trial Investigating the Effects and the Mechanisms of Defibrotide (LPS_DF)

Endotoxemia | Healthy Volunteers

Austria
University of Colorado, Boulder
Forest Laboratories

Completed

Nebivolol and Endothelial Regulation of Fibrinolysis (NERF)

Hypertension | Prehypertension

United States
University of Pennsylvania

Terminated

Dosing of Amicar and Measure of Fibrinolysis by TEG During Cardiac Surgery (EACA)

Aortic Disease

United States
Cereno Scientific AB

Completed

Study Investigation Pharmacokinetics and Pharmacodynamics of CS1

Thrombosis

Sweden
East and North Hertfordshire NHS Trust
University of Hertfordshire

Completed

Assessment of The Effect of Apixaban in AF

Atrial Fibrillation | Embolism Thrombosis

United Kingdom
Swanson Center

Completed

Sequential Compression Devices Effect on Fibrinolysis in Plastic Surgery Outpatients

Blood Coagulation Disorder

United States
Holger Thiele

Completed

Randomized Multicenter Trial of Prehospital Initiated Facilitated Percutaneous Coronary Intervention (PCI) Versus Primary PCI in ST-segment-Elevation MI (STEMI) (LIPSIA STEMI)

Myocardial Infarction

Germany
Medical Center of South Arkansas

Withdrawn

Comparing Ticagrelor and Clopidogrel Pharmacodynamics After Thrombolysis (TACAT)

Acute Coronary Syndrome | Acute ST Segment Elevation Myocardial Infarction

United States
Helsinki University Central Hospital
University of Helsinki

Unknown

Intra-graft Coagulation Events in Clinical Renal Transplantation and Delayed Graft Function (KTX)

End Stage Renal Disease | Kidney Transplantation | Reperfusion Injury | Delayed Graft Function

Finland
Brugmann University Hospital

Completed

Evaluation of the Minimum Concentration of Tranexamic Acid Required to Inhibit Fibrinolysis in a Population of Pregnant Women at Term.

Hyperfibrinolysis

Belgium
Fondation Ophtalmologique Adolphe de Rothschild

Terminated

Embolectomy in Acute SYlvian Thrombosis in Refractory or Ineligible Patients to ALteplase (EASY)

Stroke, Acute

France
Scott Allen

Completed

Correlation of Hepatitis C, Alcoholic Liver Disease, and Renal Failure With Hyperfibrinolysis in Liver Failure

Cirrhosis

United States
RenJi Hospital

Completed

EARLY Routine Catheterization After Alteplase Fibrinolysis vs. PPCI in ST-Segment-Elevation MYOcardial Infarction (EARLY-MYO)

Acute ST-segment Elevation Myocardial Infarction

China
University Hospital, Caen

Completed

Intracoronary Thrombus Assessed by OFDI After Successful Fibrinolysis And Its Impact On Myocardial Reperfusion (AODIS)

Myocardial Infarction | Intracoronary Thrombus

France
Boston Children's Hospital

Completed

Determination of the Minimal Concentration of Antifibrinolytics Required to Inhibit t-PA-activated Fibrinolysis

Congenital Heart Disease | Fibrinolysis | Rotational Thromboelastometry

United States
Vanderbilt University

Terminated

Renin-Angiotensin and Fibrinolysis in Humans: Effect of Long-Term PDE5 Inhibition on Glucose Homeostasis

Impaired Glucose Tolerance

United States
Vanderbilt University

Withdrawn

Intracoronary Bradykinin Mediated t-PA Release in Heart Transplant Recipients (P1A4D)

Heart Transplantation

United States
University Hospital, Caen

Unknown

Interest of Thromboelastography (ROTEM) as a Biomarker of Revascularisation in Stroke (ROTEMPredict)

Stroke

France
Vanderbilt University

Withdrawn

Brachial Artery t-PA Release in Heart Transplant Recipients (P1A3C)

Heart Transplantation

United States
Hu Hao

Unknown

Serum Betatrophin Levels and Its Influencing Factors in Patients With Hyperthyroidism

Hyperthyroidism

China
Stanford University

Completed

Fibrinolysis Before Cardiopulmonary Bypass?

Pathologic Fibrinolysis

United States
NYU Langone Health
Guerbet

Completed

Effects Contrast on Platelet Activity, Thrombosis and Fibrinolysis in Patients Undergoing Coronary Angiography

Coronary Artery Disease

United States
Vanderbilt University
National Heart, Lung, and Blood Institute (NHLBI); University of Washington

Terminated

Genes, Fibrinolysis and Endothelial Dysfunction- Dialysis Aim 3

Endothelial Dysfunction | Oxidative Stress

United States
Chiang Mai University

Completed

The Short- and Long Term Outcomes of Early Routine PCI With the Standard Treatment in Low-intermediate Risk ST-elevation Myocardial Infarction Patients Who Successfully Fibrinolysis.

ST-elevation Myocardial Infarction

Thailand
University of Patras

Completed

Ticagrelor vs High Dose Clopidogrel in Patients With ST Elevation Myocardial Infarction Post Fibrinolysis

ST Elevation Myocardial Infarction | Fibrinolysis | P2Y12 Inhibitor

Greece
Children's Mercy Hospital Kansas City

Completed

Treatment of Abdominal Abscesses With or Without Fibrinolysis

Abdominal Abscess | Tissue Plasminogen Activator

United States
Vanderbilt University
National Institutes of Health (NIH)

Completed

Renin Angiotensin Aldosterone System (RAAS) and Fibrinolysis in Humans: ACEi and PE5i

Metabolic Syndrome
Universidade Federal do Rio de Janeiro
Rio de Janeiro State Research Supporting Foundation (FAPERJ)

Completed

Prevalence of Clinical and Laboratory Markers of Hypofibrinolysis in Psychotic Patients

Insulin Resistance | Thrombophilia | Psychosis

Brazil
Supergene, LLC

Unknown

Single Bolus Recombinant Nonimmunogenic Staphylokinase (FORtelyzin) Versus Single Bolus Tenecteplase (Metalyse) in STEMI (FORMAT-1)

Myocardial Infarction

Russian Federation
Clinical Research Support Center Kyush

Unknown

Oral Steroids for Regorafenib-induced Fatigue/Malaise in Unresectable mCRC (KSCC1402/HGCSG1402)

Rectal Cancer

Japan
Richard Chang, M.D.
National Institutes of Health Clinical Center (CC)

Completed

Low-Dose Alteplase to Treat Blood Clots in Deep Leg Veins

Acute Deep Venous Thrombosis of the Lower Extremity

United States
AHS Cancer Control Alberta

Unknown

Pilot Study of 18F-FAZA in Assessing Early Functional Response in Patients With Inoperable Non Small Cell Lung Cancer Undergoing Radiotherapy or Chemo-radiotherapy

Lung Neoplasm | Cell Hypoxia

Canada
Boehringer Ingelheim

Completed

Effects of Steady State Tipranavir/Ritonavir or Darunavir/Ritonavir or Ritonavir on Platelet Function, Coagulation and Fibrinolysis Biomarkers in Healthy Subjects

Healthy
Centre Chirurgical Marie Lannelongue

Completed

Tranexamic Acid (TXA) in Pediatric Cardiac Surgery (Exacyl)

Bleeding

France
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Brown Adipose Tissue and Body Mass Index

Obesity | Type 2 Diabetes Mellitus

Netherlands
Policlinico Hospital
Eli Lilly and Company

Completed

Effect of Hyperglycemia in PAI-1 Activity and the Relationship With Outcome in Severe Sepsis and Septic Shock

Septic Shock | Severe Sepsis

Italy
Vanderbilt University

Completed

Bradykinin Receptor Antagonism During Cardiopulmonary Bypass (BRAC)

Inflammation | Surgery | Cardiopulmonary Bypass | Fibrinolysis

United States
All India Institute of Medical Sciences, New Delhi

Completed

A Study Comparing a New Dosing Regimen of Clot-dissolving Drug for Mechanical Heart Valves Which Show Clots (RAFT-PVT)

Prosthetic Valve Thrombosis
Vanderbilt University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Study of Inflammation and Oxidative Stress in Persons Undergoing Dialysis

End Stage Renal Failure on Dialysis | Complication of Hemodialysis

United States
Umeå University
University of Edinburgh

Completed

Health Effects of Biodiesel Exhaust Exposure (BD100)

Vascular Endothelium

Sweden
Vanderbilt University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Completed

Renin-Angiotensin Aldosterone System and Fibrinolysis Interaction in Humans-Specific Aim 3

Obesity

United States
St. Olavs Hospital

Completed

Tranexamic Acid, Hemorrhage and Transfusions After Combined Aortic Valve Replacement and Coronary Artery Bypass Surgery.

Hemorrhage

Norway
Vanderbilt University

Completed

The RAS, Fibrinolysis and Cardiopulmonary Bypass

Coronary Artery Disease | Inflammation | Cardiopulmonary Bypass | Fibrinolysis | Angiotensin Receptor Blockers | Angiotensin Converting Enzyme

United States
Centre Hospitalier Universitaire de Nice

Completed

Clinical Efficacy of In-situ Thrombolysis in Case of Intraventricular Haemorraghia by Aneurysm Rupture

Subarachnoid Hemorrhage | Aneurysm, Ruptured

France
University of Edinburgh
Umeå University

Completed

Biodiesel Exhaust, Acute Vascular and Endothelial Responses (BEAVER)

Healthy

Sweden
University of Edinburgh
University of Aarhus; University of Oxford

Completed

The Effect of Ischaemic-reperfusion on the Endogenous Fibrinolysis in Man

Ischaemic Heart Diseases

United Kingdom
University of Edinburgh
University of Aarhus; University of Oxford

Completed

The Effect of Ischaemic-Reperfusion and Ischaemic Preconditioning on the Endogenous Fibrinolysis in Man

Ischaemic Heart Diseases

United Kingdom
Canadian Heart Research Centre
Canadian Institutes of Health Research (CIHR); Hoffmann-La Roche; Guidant Corporation

Completed

Routine Angioplasty and Stenting After Fibrinolysis for Acute Myocardial Infarction

Myocardial Infarction

Canada
Hopital Lariboisière

Completed

Effect of Aging on Haemostasis Parameters

Aging

France
ARCA Biopharma, Inc.

Completed

Trial of a Novel Fibrinolytic (Alfimeprase) to Clear Thrombosed Vascular Access Devices

Catheters, Indwelling

United States

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