Search clinical trials for: neurofibroma

Total 302 results

Children's Hospital Medical Center, Cincinnati
United States Department of Defense

Recruiting

Antioxidant Therapy With N-acetylcysteine for Children With Neurofibromatosis Type 1 (DoDNAC)

Neurofibromatosis 1

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb

Recruiting

Neoadjuvant Nivolumab Plus Ipilimumab for Newly Diagnosed Malignant Peripheral Nerve Sheath Tumor

Nerve Sheath Tumors

United States
dr. Laura C. G. de Graaff-Herder

Recruiting

GROWing Up With Rare GENEtic Syndromes (GROW UR GENES)

Disorders of Sex Development | Congenital Adrenal Hyperplasia | Tuberous Sclerosis | Kallmann Syndrome | Prader-Willi Syndrome | Neurofibromatosis | Rett Syndrome | 22q11 Deletion Syndrome | Turner Syndrome | Noonan Syndrome | Allan-Herndon-Dudley Syndrome | Saethre-Chotzen Syndrome | Congenital Hypopituitarism | Cornelia... and other conditions

Netherlands
Children's Hospital Medical Center, Cincinnati

Recruiting

RASopathy Biorepository

Neurofibromatosis 1 | Noonan Syndrome | Legius Syndrome | Cardiofaciocutaneous Syndrome | Costello Syndrome | SYNGAP1-Related Intellectual Disability | DLG4 | RAS Mutation | Noonan Syndrome With Multiple Lentigines | Noonan Neurofibromatosis Syndrome | Smith-Kingsmore Syndrome | MTOR Gene Mutation | GATOR-1 Gene... and other conditions

United States
Scott R. Plotkin, MD, PhD
Takeda; National Comprehensive Cancer Network; The Children's Tumor Foundation

Recruiting

Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2) (INTUITT-NF2)

Ependymoma | Meningioma | Neurofibromatosis Type 2 | Vestibular Schwannoma | Non-vestibular Schwannoma

United States
National Cancer Institute (NCI)

Recruiting

Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors

Colorectal Neoplasms | Advanced Breast Cancer | Advanced Solid Tumors | Malignant Peripheral Nerve Sheath Tumor | Metastatic Pancreatic Cancer | Pediatric Solid Tumor

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); American Lebanese Syrian Associated Charities...

Recruiting

A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration

Low Grade Glioma (LGG) of Brain With BRAF Aberration | High Grade Glioma (HGG) of the Brain With BRAF Aberration | Low Grade Glioma of Brain With Neurofibromatosis Type 1

United States
University of Aarhus

Recruiting

Comparison of Gastrointestinal Motility in Healthy Children and Children With Constipation

Constipation | Childhood Acute Lymphoblastic Leukemia | Neurofibromatosis 1 | Chronic Constipation With Overflow

Denmark
Novartis Pharmaceuticals

Recruiting

Pediatric Long-Term Follow-up and Rollover Study

Glioblastoma | Astrocytoma | Anaplastic Astrocytoma | Neurofibromatosis Type 1 | Anaplastic Ganglioglioma | Anaplastic Pleomorphic Xanthoastrocytoma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Diffuse Astrocytoma | Anaplastic Oligodendroglioma | Pilocytic Astrocytoma | Gangliocytoma | Central Neurocytoma | Oligodendroglioma... and other conditions

United States, Belgium, Spain, Denmark, Germany, Czechia, Italy, Australia, Russian Federation, France, Brazil, Netherlands, Japan, Canada, Finland, Sweden, United Kingdom, Argentina, Israel
Massachusetts General Hospital
United States Department of Defense

Recruiting

Resiliency Training in Adolescents With NF1 and NF2

Neurofibromatoses

United States
National Cancer Institute (NCI)

Recruiting

A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma

Neurofibromatosis Type 1 | Low Grade Glioma | Visual Pathway Glioma

United States, Canada, Puerto Rico
Seattle Children's Hospital

Recruiting

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Soft Tissue Sarcoma | Carcinoma | Osteosarcoma | Ewing Sarcoma | Rhabdoid Tumor | Neuroblastoma | Retinoblastoma | Rhabdomyosarcoma | Wilms Tumor | Hepatoblastoma | Synovial Sarcoma | Desmoplastic Small Round Cell Tumor | Germ Cell Tumor | Pediatric Solid Tumor | Clear Cell Sarcoma | Malignant Peripheral Nerve Sheath Tumors

United States
Ascentage Pharma Group Inc.
Merck Sharp & Dohme LLC

Recruiting

A Study of APG-115 in Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors

Melanoma | P53 Mutation | Uveal Melanoma | Cutaneous Melanoma | Mucosal Melanoma | Malignant Peripheral Nerve Sheath Tumors | MPNST | Unresectable or Metastatic Melanoma or Advanced Solid Tumors | MDM2 Gene Mutation

United States, Australia
Newcastle-upon-Tyne Hospitals NHS Trust
National Institute for Health Research, United Kingdom; Alder Hey Children's...

Recruiting

Airway Intervention Registry (AIR): Recurrent Respiratory Papillomatosis (RRP) (AIR:RRP)

Human Papilloma Virus | Recurrent Respiratory Papillomatosis

United Kingdom
Massachusetts General Hospital

Recruiting

Resiliency Training for Adults With Neurofibromatosis Via Live Videoconferencing

Neurofibromatoses | Neurofibromatosis 1 | Neurofibromatosis 2 | Schwannomatosis

United States
Ren tingting

Not yet recruiting

The Neurofibromatosis-associated Tumor Biobank

Neurofibromatoses
Washington University School of Medicine
Boston's Children Hospital

Recruiting

Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors

Malignant Peripheral Nerve Sheath Tumors

United States, Canada, United Kingdom, India
Massachusetts Eye and Ear Infirmary
Massachusetts General Hospital; United States Department of Defense

Recruiting

Study of Aspirin in Patients With Vestibular Schwannoma

Neurofibromatosis 2 | Vestibular Schwannoma | Acoustic Neuroma

United States
St. Jude Children's Research Hospital

Recruiting

Familial Investigations of Childhood Cancer Predisposition (SJFAMILY)

Pancreatic Cancer | Hodgkin Lymphoma | Lynch Syndrome | Tuberous Sclerosis | Fanconi Anemia | AML | Non Hodgkin Lymphoma | Familial Adenomatous Polyposis | Acute Leukemia | Nevoid Basal Cell Carcinoma Syndrome | Neurofibromatosis Type 1 | Neuroblastoma | Retinoblastoma | MDS | Rhabdomyosarcoma | Von Hippel-Lindau Disease | Adrenocortical Carcinoma and other conditions

United States
Vanderbilt University
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Interventions for Reading Disabilities in NF1

Neurofibromatosis Type 1 | Reading Disability | NF1 | Learning Disability

United States
Spectrum Health Hospitals
Van Andel Research Institute

Recruiting

Targeting the Mechanisms Underlying Cutaneous Neurofibroma Formation in NF1: A Clinical Translational Approach.

Neurofibromatosis Type 1 | Plexiform Neurofibromas | Cutaneous Neurofibromas

United States
Donald Basel

Recruiting

Photodynamic Therapy for Benign Dermal Neurofibromas- Phase II

NEUROFIBROMATOSIS 1

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Vaccine Therapy in Treating Patients With Malignant Peripheral Nerve Sheath Tumor That is Recurrent or Cannot Be Removed by Surgery

Neurofibromatosis Type 1 | Metastatic Malignant Peripheral Nerve Sheath Tumor | Recurrent Malignant Peripheral Nerve Sheath Tumor

United States
National Cancer Institute (NCI)

Recruiting

Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)

Neurofibromatosis 1 | Plexiform Neurofibromas

United States
National Cancer Institute (NCI)

Recruiting

Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...

Sarcoma | Precursor Cell Lymphoblastic Leukemia-Lymphoma | Neurofibroma, Plexiform | Leukemia, Promyelocytic, Acute

United States
The Children's Tumor Foundation

Recruiting

Neurofibromatosis (NF) Registry Portal

Neurofibromatosis 1 | Neurofibromatosis 2 | Schwannomatosis

United States
National Institute of Neurological Disorders and...

Recruiting

Natural History Study of Patients With Neurofibromatosis Type 2

Neurofibromatosis

United States
National Cancer Institute (NCI)

Active, not recruiting

Natural History Study of Patients With Neurofibromatosis Type I

Neurofibroma | Neurofibromatosis Type 1 | Malignant Peripheral Nerve Sheath Tumor | Optic Glioma | Plexiform Neurofibroma

United States
National Cancer Institute (NCI)

Completed

Relationship Stressors in Parents of Children With Cancer or Neurofibromatosis Type 1 (NF1)

Parents of Children With Cancer | Parents of Children With NF1 | Parents of Children With Neurofibromatosis Type I

United States, Canada
National Cancer Institute (NCI)

Completed

Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1

Neurofibromatosis | MPNST

United States
National Cancer Institute (NCI)

Completed

Study of Disease Severity in Adults With Neurofibromatosis Type 1 (NF1)

Neurofibromatosis Type 1 | Legius Syndrome

United States
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

Malignant Solid Neoplasm | Nasopharyngeal Carcinoma | Adenoid Cystic Carcinoma | Transitional Cell Carcinoma | Cholangiocarcinoma | Intrahepatic Cholangiocarcinoma | Chordoma | Gestational Trophoblastic Tumor | Pseudomyxoma Peritonei | Cervical Adenocarcinoma | Vaginal Adenocarcinoma | Vaginal Squamous Cell... and other conditions

United States, Guam
National Cancer Institute (NCI)

Enrolling by invitation

Analysis of Data Collected From Individuals Administered Neurobehavioral Assessments

HIV | Neurofibromatosis Type 1 | Brain Tumors

United States
Children's Hospital Medical Center, Cincinnati
AstraZeneca

Suspended

Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors (SEL-TH-1601)

Glioma | Ependymoma | Meningioma | Neurofibromatosis 2 | Vestibular Schwannoma

United States
National Cancer Institute (NCI)

Completed

Medication Adherence in Children, Adolescents and Adults With Neurofibromatosis Type 1(NF1) on Clinical Treatment Trials

Neurofibromatosis 1 | Neurofibroma, Plexiform

United States
National Cancer Institute (NCI)

Active, not recruiting

AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors

Neurofibromatosis 1 | Neurofibroma, Plexiform | Neurofibromatosis Type 1 | NF1

United States
National Cancer Institute (NCI)

Completed

Validating Pain Scales in Children and Young Adults

Leukemia | Solid Tumor | Sickle Cell Disease | Neurofibromatosis

United States
National Cancer Institute (NCI)

Active, not recruiting

MEK 1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas

Neurofibromatosis 1 (NF1) | Plexiform Neurofibromas (PN)

United States
Radboud University Medical Center

Completed

The Effects of Medication Induced Blood Pressure Reduction on Cerebral Hemodynamics in Hypertensive Frail Elderly (BLUEBERRY)

Hypertension | Frailty | Orthostatic Hypotension | Orthostatic Intolerance | Cerebral Hypoperfusion | Old Age; Dementia

Netherlands
AstraZeneca
Merck Sharp & Dohme LLC

Active, not recruiting

Phase I Study to Assess the Effect of Food on the PK and Gastrointestinal Tolerability of Selumetinib in Adolescent Children With Neurofibromatosis Type 1 Related Plexiform Neurofibromas

Neurofibromatosis Type 1

United States, Spain, Poland, Russian Federation
AstraZeneca
Merck Sharp & Dohme LLC

Active, not recruiting

Pharmacokinetics, Safety and Efficacy of the Selumetinib Granule Formulation in Children Aged ≥1 to <7 Years With NF1-related Symptomatic, Inoperable PN (SPRINKLE)

Neurofibromatosis Type 1

United States, Spain, Germany, Netherlands, Russian Federation, Italy, Japan
National Cancer Institute (NCI)

Completed

Natural History and Biology of Skin Neurofibromas in Neurofibromatosis Type 1

Neurofibroma | Neurofibromatosis Type 1

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing Whether Cancers With Specific Mutations Respond Better to Glutaminase Inhibitor, Telaglenastat Hydrochloride, Anti-Cancer Treatment, BeGIN Study

Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | NF1 Mutation Positive Malignant Peripheral Nerve Sheath Tumor

United States
AstraZeneca
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of Selumetinib in Chinese Paediatric and Adult Subjects With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN)

Neurofibromatosis 1 | Neurofibroma Plexiform

China
Nicholas Gulati

Completed

DPCP to Treat Cutaneous Neurofibromas Associated With NF1

Cutaneous Neurofibroma

United States
Aveni Foundation

Available

BLESSED: Expanded Access for DeltaRex-G for Advanced Pancreatic Cancer, Sarcoma and Carcinoma of Breast

Sarcoma | Soft Tissue Sarcoma | Pancreatic Cancer | Osteosarcoma | Chondrosarcoma | Chordoma | Carcinoma of Breast | MPNST (Malignant Peripheral Nerve Sheath Tumor)

United States
Pfizer

Active, not recruiting

PF-07284892 in Participants With Advanced Solid Tumors

Solid Tumor

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease

Castleman Disease | Lymphangioleiomyomatosis | Digestive System Carcinoma | Malignant Neoplasm | Recurrent Breast Carcinoma | Recurrent Thyroid Gland Carcinoma | Metastatic Urothelial Carcinoma | Malignant Female Reproductive System Neoplasm | Neurofibromatosis Type 2 | Recurrent Adult Soft Tissue Sarcoma and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma

Low Grade Glioma | Recurrent Visual Pathway Glioma | Refractory Visual Pathway Glioma | Recurrent Childhood Pilocytic Astrocytoma | Recurrent Neurofibromatosis Type 1 | Refractory Neurofibromatosis Type 1

United States
Seattle Children's Hospital

Active, not recruiting

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Melanoma | Soft Tissue Sarcoma | Carcinoma | Osteosarcoma | Ewing Sarcoma | Rhabdoid Tumor | Neuroblastoma | Retinoblastoma | Rhabdomyosarcoma | Wilms Tumor | Hepatoblastoma | Synovial Sarcoma | Desmoplastic Small Round Cell Tumor | Germ Cell Tumor | Pediatric Solid Tumor | Clear Cell Sarcoma | Malignant Peripheral Nerve Sheath...

United States

Search clinical trials for: neurofibroma

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