Search clinical trials for: physiological effects of drugs

Total 452953 results

Poznan University of Medical Sciences

Not yet recruiting

Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Knee Arthroplasty

Knee Osteoarthritis | Knee Arthritis | Knee Pain Chronic | Knee Disease

Poland
Poznan University of Medical Sciences

Not yet recruiting

Two-level ESPB in Total Knee Arthroplasty

Knee Osteoarthritis | Knee Arthritis | Knee Pain Chronic

Poland
Yuanquan Yang

Not yet recruiting

Siltuximab for the Prevention of Severe Immune-Related Adverse Events During Immune Checkpoint Inhibitor Rechallenge in Patients With Advanced Cancer, CIRES Trial

Advanced Malignant Solid Neoplasm | Hematopoietic and Lymphatic System Neoplasm

United States
Aalborg University

Not yet recruiting

Investigation of Corticospinal Excitability Aspects of Itch and Pain

Pain | Itch
Ohio State University
Patient-Centered Outcomes Research Institute; Northwestern University; Preeclampsia...

Not yet recruiting

Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL (ASPIRIN)

Preeclampsia | Gestational Hypertension | Hypertensive Disorders of Pregnancy

United States
AstraZeneca
Daiichi Sankyo Company, Limited 3-5-1 Nihonbashihoncho, Chuo-ku, Tokyo

Not yet recruiting

Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer (DESTINY-BTC01)

Biliary Tract Cancer

Belgium, Canada, Brazil, Japan, Korea, Republic of, Taiwan, Germany, Austria, Netherlands
Chinese University of Hong Kong

Recruiting

Boiled Tree Nut for Oral Immunotherapy in Food-allergic Children

Food Allergy | Food Allergy in Children

Hong Kong
Fujian Cancer Hospital

Not yet recruiting

Short-course Radiotherapy Combined With Sintilimab for Neoadjuvant Treatment of Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma
Assiut University

Recruiting

Efficacy of Hyaluronic Acid in Prevention of Acute Radiation Proctitis

Acute Radiation Enteritis | Acute Radiation Proctitis

Egypt
University of East Anglia
Clinical Research and Trials Unit (Norfolk & Norwich University Hospital,...

Recruiting

The Role of SGLT2i in Management of Moderate AS

Moderate Aortic Valve Stenosis

United Kingdom
Xianmin Song, MD

Recruiting

Reduced Intensity Conditioning With Thiotepa Combined With Bu/Flu/Ara-C in Allo-HSCT for Relapsed or Refractory Peripheral T-cell Lymphoma.

Peripheral T Cell Lymphoma

China
Shanghai Zhongshan Hospital

Not yet recruiting

Synergistic Effects of PD-1 Antibody and Chemotherapy Followed by Surgery in Limited-metastatic G/GEJ Adenocarcinoma (ROSETTE)

Gastric Cancer | GastroEsophageal Cancer

China
Peking University First Hospital
Peking University International Hospital; Tianjin Medical University General...

Not yet recruiting

Dexmedetomidine-Esketamine Combination for Sedation and Analgesia in ICU Patients

Delirium | Dexmedetomidine | Aged | Intensive Care Units | Esketamine | Ventilators, Mechanical

China
Hospital de Clinicas de Porto Alegre

Not yet recruiting

The Impact of Geriatric Assessment on the Treatment Plan of Elderly Patients With T2DM

Frail Elderly Syndrome | Frailty | Geriatric Assessment | Type2diabetes

Brazil
National Aeronautics and Space Administration (NASA)

Recruiting

Effect of Sex on Orthostatic Intolerance and Cardiovascular Response During Lunar Descent and Ascent (Lunar OI)

Healthy

United States
Assuta Ashdod Hospital

Not yet recruiting

Oxytocin Effectiveness in First Trimester Dilatation and Curettage - a Double Blind Placebo Controlled Randomized Trial

Missed Abortion
Ain Shams University

Recruiting

Does Non-Steroidal Anti-inflammatory Drugs Decrease the Quality of Pleurodesis After Mechanical Pleural Abrasion/Pleurectomy for Treatment of Pneumothorax?

Primary and Secondary Spontaneous Pneumothorax

Egypt
Regeneron Pharmaceuticals

Not yet recruiting

A Study to Learn if 27T51, a Mucin-16 (MUC16) Protein Targeting Immune Cell Therapy, Administered Alone or in Combination is Safe and How Well it Works for Adult Participants With Recurrent or Treatment Resistant Ovarian Cancers

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Carcinoma

United States
United States Army Research Institute of Environmental...

Not yet recruiting

The Effects of Semaglutide on Body Composition and Performance in Military Personnel

Obesity
Universitaire Ziekenhuizen KU Leuven

Not yet recruiting

Impact of Drainless Donor Abdominal Site in Deep Inferior Epigastric Perforator (DIEP) Flap on Complications and Duration of Hospital Stay.

Breast Reconstruction

Belgium
Ruijin Hospital

Recruiting

A Trial on the Recurrence Free Survival Rate of Type I AIP With High-risk of Recurrence

Type 1 AIP

China
Steno Diabetes Center Copenhagen
Aarhus University Hospital

Recruiting

Automated Insulin Delivery for Type 1 Diabetes - Beyond Glucose Metrics (AID-BEYOND)

Diabetes Mellitus, Type 1

Denmark
Peking University People's Hospital

Not yet recruiting

Fertility Sparing Therapy for Patients With Stage IA G2 Endometrial Cancer

Carcinoma, Endometrioid | Fertility Preservation
Luye Pharma Group Ltd.

Recruiting

Phase II Clinical Trial to Evaluate the Efficacy and Safety of LPM3480392 Injection for Moderate to Severe Pain After Orthopedic Surgery

Pain, Postoperative

China
Brigham and Women's Hospital
National Institute of General Medical Sciences (NIGMS)

Not yet recruiting

Understanding the Acute Pain Phenotype in Patients Undergoing Surgery

Acute Pain | Opioid Use | Chronic Post Operative Pain

United States
University of Aarhus

Recruiting

Strategy for Withdrawal of Pharmacological Treatment for Urinary Incontinence in Children (StayDry)

Urinary Incontinence in Children

Denmark
Second Affiliated Hospital, School of Medicine,...
Huashan Hospital; The Affiliated Nanjing Drum Tower Hospital of Nanjing University... and other collaborators

Not yet recruiting

Tract-based Artificial Intelligence (AI) Robot Guiding System in Basal Ganglion Hemorrhage Evacuation

Basal Ganglia Hemorrhage

China
Radboud University Medical Center

Not yet recruiting

Methylphenidate in KBG Syndrome: N-of-1 Series (KBGS_N_of_1)

ADHD - Combined Type | Kbg Syndrome
David Ilan Sandberg

Not yet recruiting

Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS Malignancies

Recurrent Ependymoma | Recurrent Medulloblastoma | CNS Malignancies

United States
Tanta University

Not yet recruiting

Fexofenadine Versus Gabapentin for Uremic Pruritus in Patients on Regular Hemodialysis

Hemodialysis | ESRD | Renal Replacement Therapy | End-stage Renal Disease | Uremic Pruritus | Chronic Kidney Disease-associated Pruritus

Egypt
Ferring Pharmaceuticals

Recruiting

An Exploratory Study to Investigate the Effect of FE 999302 When Given Together With Follitropin Delta During Controlled Ovarian Stimulation (Celestial-1)

Fertility

Czechia
Stefano Vicari
Italian Institute of Technology (IIT)

Recruiting

Efficacy of Bumetanide to Improve Cognitive Functions in Down Syndrome

Down Syndrome

Italy
University of Chile
Centro FONDAP de Gerociencia, Salud mental y Metabolismo (GERO); Center for...

Recruiting

Nicotinamide Supplementation Improves Physical Performance in Older Adults at Risk of Falls (NICE-FIT)

Frailty | Fall | Frailty Syndrome | Falls

Chile
TC Erciyes University

Not yet recruiting

Comparing Inhalation and Total Intravenous Anesthesia Methods

Hernia, Inguinal | Children

Turkey
Mansoura University

Recruiting

Investigate"Clinically" the Effectiveness of Boswellia Based Intracanal Medication Compared to Calcium Hydroxide Ca(OH)2 and Ledermix on the Levels of Bacteria and Inflammatory Cytokines in Root Canals and Periradicular Tissues of Teeth With Apical Periodontitis

Microbial Colonization

Egypt
Yale University
Wallace Research Foundation

Not yet recruiting

Mechanistic Studies of Psilocybin in Headache Disorders

Migraine

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Pain Reduction for Limb Injuries in Pediatric Emergency Departments: Intranasal Fentanyl or Intranasal Ketamine vs Oral Morphine (ANTAMIN)

Limb Injury

France
Hospital do Coracao
Brazilian Research in Intensive Care Network (BRICNet)

Not yet recruiting

Norepinephrine and Vasopressin for Rescue Versus Early Vasopressin for Vasopressor Dependent Sepsis (NoVa)

Septic Shock

Brazil
Institute of Hematology & Blood Diseases Hospital...

Recruiting

A Prospective Clinical Study of CD3-CD20 Bisspecific Antibody Based Therapy Combined With CD19-CAR T Cells in the Treatment of Relapsed Refractory B-cell Non-Hodgkin Lymphoma

B-cell Non-Hodgkin Lymphoma

China
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...
EMD Serono Research & Development Institute, Inc.

Not yet recruiting

Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

Generalized Myasthenia Gravis

United States, Germany
Nanjing IASO Biotechnology Co., Ltd.

Recruiting

A Phase III Study of Eque-cel in Subjects With Len-refractory RRMM (FUMANBA-03) (FUMANBA-03)

Multiple Myeloma

China
Pfizer

Not yet recruiting

A Study to Learn About the Study Medicine PF-07220060 Together With Letrozole Compared to Letrozole Alone in Women Post Menopause

Breast Cancer
University of Sao Paulo
University of Campinas, Brazil; Faculdade de Medicina do ABC

Recruiting

Use of Botulinum Toxin A in Direct Eyebrow Lift Scar

Skin Scarring | Eyebrow Ptosis

Brazil
Aretaieion University Hospital

Recruiting

Opioid-based Versus Opioid-free Endotracheal Intubation

Anesthesia | Opioid Use | Fentanyl | Analgesic Non-narcotic | Anesthesia Intubation

Greece
Francois Corbin

Not yet recruiting

Association Between Serum and Neuroimaging Measurements of the GABAergic System

GABAergic System
Egymedicalpedia

Recruiting

Dexmedetomidine Versus Midazolam-Fentanyl for Analgesia and Sedation

Valvular Cardiac Surgeries

Egypt
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Effect of Recombinant Human Brain Natriuretic Peptide on Ventricular Remodeling and Cardiac Function in Patients With Acute Anterior Myocardial Infraction Undergoing Percutaneous Coronary Intervention

Ventricular Remodeling | Myocardial Infarction, Anterior Wall

China
State University of New York at Buffalo

Not yet recruiting

Metformin as an add-on or Monotherapy in Treatment of Aging People With Multiple Sclerosis (MS)

Multiple Sclerosis
Belfast Health and Social Care Trust

Recruiting

CMR Right Ventricular Contractile Reserve Following Lung Resection

Lung Cancer | Surgery | Anesthesia

United Kingdom
Mỹ Đức Hospital

Not yet recruiting

Cerclage With Progesterone Versus Progesterone Only in Singleton Pregnancies (RESILIENT)

Preterm Birth | Short Cervix

Vietnam

Search clinical trials for: physiological effects of drugs

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