Search clinical trials for: severe sepsis without obvious infection

Total 70229 results

University of South Florida

Recruiting

Dupilumab Severe Eosinophilic Chronic Sinusitis Without Nasal Polyposis

Severe Eosinophilic Chronic Sinusitis Without Nasal Polyposis

United States
Oslo University Hospital

Recruiting

Sepsis: From Syndrome to Personalized Care

Sepsis | Septic Shock | Sepsis Syndrome | Sepsis, Severe

Norway
Alberta Health Services, Calgary

Recruiting

Therapeutic Plasma Exchange in Adult Patients With Severe Sepsis

Septic Shock

Canada
Dascena
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Baystate Health; Cape... and other collaborators

Recruiting

Machine Learning Sepsis Alert Notification Using Clinical Data (HindSight P2)

Sepsis | Septic Shock | Severe Sepsis

United States
Spectral Diagnostics (US) Inc.

Recruiting

Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study (TIGRIS)

Septic Shock | Endotoxemia

United States
Dascena

Not yet recruiting

Unsupervised Machine Learning for Clustering of Septic Patients to Determine Optimal Treatment

Sepsis | Septic Shock | Severe Sepsis
University of Florida

Recruiting

LIPIDS-P Trial Phase I/II (LIPIDS-P)

Septic Shock | Sepsis, Severe

United States
Suez Canal University

Recruiting

Bispectral Index (BIS) for Classification of Procalcitonin (PCT) Sepsis Grades in Critically Ill Patients With Sepsis (BIS6)

Sepsis, Severe

China
Dr. Damon Scales
Canadian Institutes of Health Research (CIHR); Sunnybrook Research Institute

Recruiting

Paramedic Initiated Treatment of Sepsis Targeting Out-of-hospital Patients (PITSTOP) (PITSTOP)

Severe Sepsis or Septic Shock

Canada
University of Ulm

Recruiting

Monocyte Profiles in Critically Ill Patients With Pseudomonas Aeruginosa Sepsis (MIPSA)

Sepsis | Critically Ill | Pseudomonas Infections | Sepsis, Severe | Pseudomonas Septicemia | Pseudomonas; Pneumonia | Pseudomonal Bacteraemia | Pseudomonas Urinary Tract Infection | Pseudomonas Gastrointestinal Tract Infection

Germany
Infectopharm Arzneimittel GmbH
INPADS GmbH; Dr. Oestreich + Partner GmbH

Recruiting

Fosfomycin i.v. for Treatment of Severely Infected Patients (FORTRESS)

Respiratory Tract Infections | Sepsis | Encephalitis | Bacterial Infections | Intraabdominal Infections | Bacteremia | Skin Diseases, Bacterial | Pneumonia, Bacterial | Urinary Tract Infections | Meningitis, Bacterial | Central Nervous System Bacterial Infections | Soft Tissue Infections | Endocarditis, Bacterial | Bone Diseases, Infectious and other conditions

Germany, Austria, Greece, Italy, United Kingdom
Seoul National University Hospital
Chonbuk National University Hospital; Samsung Medical Center; Asan Medical Center and other collaborators

Recruiting

Severe Sepsis and Septic Shock Registry

Sepsis

Korea, Republic of
Ospedale Santa Maria delle Croci

Recruiting

Short-course Antimicrobial Therapy in Sepsis

Sepsis | Septic Shock | Severe Sepsis | Infection

Italy
Ruilan Wang
Changhai Hospital; Shanghai Jiao Tong University School of Medicine; Shanghai... and other collaborators

Recruiting

The Effect of REcombinant Human Thrombopoietin (rhTPO) on Sepsis Patients With aCUte Severe thrombocytopEnia (RESCUE)

Sepsis | Thrombocytopenia

China
Centre Hospitalier Universitaire de Nīmes

Recruiting

L-carnitine as an Adjunct Treatment for Septic Shock Patients With Acute Kidney Injury (CarniSave)

Shock, Septic | Acute Kidney Injury | Severe Sepsis

France
China Medical University, China
The First Affiliated Hospital of Nanchang University; Peking University People... and other collaborators

Recruiting

Efficacy and Safety of Unfractionated Heparin on Severe Sepsis With Suspected Disseminated Intravascular Coagulation

Sepsis | Disseminated Intravascular Coagulation

China
Jiang Jianxin
Second Affiliated Hospital, School of Medicine, Zhejiang University; Huazhong... and other collaborators

Recruiting

Prediction Study of Complications After Severe Trauma (PSCAT)

Sepsis | Trauma | Multiple Organ Dysfunction Syndrome

China
Mahidol University

Recruiting

Severe Sepsis/Septic Shock on Admission to the General Surgical ICU

Septic Shock | Multiple Organ Failure | Fatal Outcome

Thailand
The University of Texas Health Science Center,...

Recruiting

Alveolar Dead Space as Predictor of Organ Failure in Severe Sepsis

Sepsis | Septic Shock | Severe Sepsis | Multi-organ Failure

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known Immunocompromise

CMV | HPV | EBV | HSV | VZV

United States
Janssen Vaccines & Prevention B.V.

Completed

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-Mediated COVID-19 in Adult Participants (ENSEMBLE)

Participants With or Without Stable Co-morbidities Associated With Progression to Severe COVID-19 at Different Stages of the Protocol

United States, Mexico, South Africa, Brazil, Chile, Colombia, Peru, Argentina
CTI BioPharma

Terminated

PRE-VENT Study in Hospitalized Patients With Severe COVID-19 With or Without Cancer

COVID-19 | COVID | COVID19

United States
Janssen Vaccines & Prevention B.V.

Completed

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults (ENSEMBLE 2)

Participants With or Without Stable Co-morbidities Associated With Progression to Severe COVID-19

United States, United Kingdom, Belgium, Spain, France, Germany, Philippines, Brazil, Colombia, South Africa
LigaChem Biosciences, Inc.

Terminated

A Phase 2a Study, Effect of Vancomycin With vs Without Delpazolid (LCB01-0371) in Patients With MRSA Bacteremia

MRSA Bacteremia

Korea, Republic of
University Hospital, Basel, Switzerland
Swiss Personalized Health Network (SPHN); Personalized Health and Related Technologies...

Terminated

Molecular Biomarkers for Sepsis

Sepsis | Infection, Bacterial | Severe Community-acquired Pneumonia (sCAP)

Switzerland
University of Vermont
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Zinc Therapy in Critical Illness

Severe Sepsis

United States
Regeneron Pharmaceuticals

Terminated

COVID-19 Study to Evaluate Safety, Tolerability, and Efficacy of REGN14256+Imdevimab for the Treatment of COVID-19 Adult and Adolescent Patients Without Risk Factors for Progression to Severe Disease

SARS-CoV-2

United States
Uppsala University Hospital
Sepsisfonden

Completed

Health Related Quality of Life After Intensive Care for Sepsis, a National Cohort Study.

Sepsis | Septic Shock | Sepsis, Severe
General and Teaching Hospital Celje

Completed

Assessement of Microcirculation With NIRS Predicts Sepsis Development in Patients With Severe Covid-19 Pneumonia

Sepsis

Slovenia
George Washington University

Completed

Intravenous AII for the Treatment of Severe Hypotension in High Output Shock: A Pilot Study (ATHOS)

Septic Shock

United States
Johns Hopkins University
Rush University Medical Center; University of California, San Francisco; amfAR...

Completed

COVID-19 Recovery Study: Symptoms and Biomarkers of Long COVID-19 in People Living With and Without HIV

HIV | Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2)

United States
Northern State Medical University

Completed

The Effect pf Goal-directed De-escalation in ARDS on Organ Function and Mortality

ARDS, Human | Sepsis, Severe

Russian Federation
Hospital Moinhos de Vento

Terminated

Seven Versus 14 Days of Antibiotic Therapy for Multidrug-resistant Gram-negative Bacilli Infections (OPTIMISE)

Sepsis | Gram-Negative Bacterial Infections | Bacteremia | Severe Infection | Bloodstream Infection | Acinetobacter Infections | Pseudomonas Aeruginosa | Human | Carbapenem-Resistant Enterobacteriaceae Infection | Carbapenem Resistant Bacterial Infection

Brazil
Centre Hospitalier Universitaire Dijon

Completed

COrporeal Compression at the ONset of Severe Sepsis and Septic Shock (COCOON)

Fluid Resuscitation | Severe Sepsis or Septic Shock

France
University Hospital, Clermont-Ferrand
Laboratoire HEMOTECH

Withdrawn

Catheter Dysfunction Rate in Patients Undergoing Kidney Replacement Therapy. Evaluation of the Safety and Efficacy of Anti-reflux Valves Without Heparin Lock Solution (DUKE)

Chronic Renal Failure | Haemodialysis, Haemodiafiltration, Haemofiltration | Kidney Replacement Therapy | Catheter Infection, Catheter Dysfunction, Catheter Related Bloodstream Infections

France
Universitaire Ziekenhuizen KU Leuven
Federaal Kenniscentrum voor Gezondheidszorg, Belgium

Completed

Early Administration of Vitamin C in Patients With Sepsis or Septic Shock in Emergency Departments (c-easie)

Sepsis | Septic Shock | Sepsis, Severe

Belgium
Assistance Publique - Hôpitaux de Paris

Completed

Predictive Mini-bolus Fluid Responsiveness in Pediatric Septic Shock (PRECISE)

Severe Sepsis or Septic Shock in Pediatric Intensive Care Unit

France
Makerere University
Radboud University Medical Center; University of Bergen

Active, not recruiting

Early Versus Late BCG Vaccination in HIV-1 Exposed Infants in Uganda in Uganda

Diarrhoea | Septicaemia | Severe Illness | Lower Respiratory Infection

Uganda
Research & Diagnostic Antibodies
National Institute of General Medical Sciences (NIGMS)

Terminated

Plasma Inducible Nitric Oxide Synthase (iNOS) Assay and Sepsis Study (PliNOSa® Test)

Sepsis | Septic Shock | Severe Sepsis
The Republican Research and Practical Center for...
Belarusian State Medical University

Enrolling by invitation

Study of Leukocyte Immunophenotype and the Lipid Transport System as Predictive Biomarkers of Severe Bacterial Infections

Sepsis | Pneumonia, Bacterial | Infective Endocarditis

Belarus
Novartis Pharmaceuticals

Completed

A Randomized, Open, Parallel, Controlled, Multi-center, Interventional, Cross-sectional Study to Evaluate the Detection Rate of Psoriatic Arthritis in Korean Moderate-to-severe Psoriasis Patients, With or Without Active Screening for Arthritis in Psoriasis (ASAP Study) (ASAP)

Psoriasis

Korea, Republic of
Southeast University, China

Completed

Effects of Glucocorticoid Combined With Vitamin C and Vitamin B1 on Microcirculation in Severe Septic Shock

Septic Shock

China
King Abdul Aziz Specialist Hospital

Completed

Effect of Bronchoscopy on the Outcome of Patients With Severe Sepsis With ARDS and Complicated by VAP From Prolonged Ventilation

Septic Shock | ARDS

Saudi Arabia
King Abdul Aziz Specialist Hospital

Completed

Effect of Bronchoscopy on the Outcome of Patients With Severe Sepsis With ARDS and Complicated by VAP From Prolonged Ventilation

Septic Shock | ARDS

Saudi Arabia
Guangdong Provincial Hospital of Traditional Chinese...

Completed

The Efficacy of Si-Ni-Tang (a Chinese Herbal Formula) for Severe Sepsis

Severe Sepsis

China
Chang Gung Memorial Hospital

Completed

Application of Serial Body Composition Change for Risk Prediction in Treating Patients With Severe Pneumonia

Pneumonia

Taiwan
Assistance Publique - Hôpitaux de Paris

Completed

Septic cArdiac Deficiency and MenIngococcal seveRe Sepsis (SAMIRA)

Septic Shock | Meningococcal Infections | Severe Sepsis

France
Bluejay Diagnostics, Inc.

Active, not recruiting

Symphony IL-6 Cutoff Establishment Study for Patients at Risk of Severe Sepsis Due to COVID-19

Severe Sepsis

United States
Emory University
National Cancer Institute (NCI)

Active, not recruiting

Best Supportive Care With or Without Low Dose Whole Lung Radiation Therapy for the Treatment of COVID-19 (RESCUE1-19)

Severe Acute Respiratory Syndrome | Pneumonia | Symptomatic COVID-19 Infection Laboratory-Confirmed

United States
Dartmouth-Hitchcock Medical Center

Completed

ED Tracking Sheet Implementation

Sepsis | Systemic Inflammatory Response Syndrome | Severe Sepsis

United States

Search clinical trials for: severe sepsis without obvious infection

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