Search clinical trials for: small change

Total 21495 results

Helsinn Healthcare SA

Completed

A Study to Evaluate the Efficacy and Safety of Anamorelin HCl for the Treatment of Malignancy Associated Weight Loss and Anorexia in Adult Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer | Cachexia; Cancer

United States, Croatia, Australia, Belgium, Russian Federation, Poland, Romania, Ukraine
Jussi Sutinen
Helsinki University Central Hospital; University of Helsinki

Active, not recruiting

The Effect Tenofovir Disoproxil Fumarate (TDF) and Tenofovir Alafenamide (TAF) on Small Intestine Gut Wall (TENENTOX)

HIV Infections | Weight Gain

Finland
Oliver Kimberger

Completed

Evaluation of a Licensed Double-sensor-heat-flux (DHF) Non-invasive Core Temperature Sensor in Small Children and Toddlers Undergoing Surgery

Hypothermia; Anesthesia

Austria
Duke University
University of Pennsylvania; National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health (NIH) and other collaborators

Completed

Cognitive Effects of Body Temperature During Hypothermic Circulatory Arrest

Cognition Disorders

United States
AbbVie

Active, not recruiting

Study to Evaluate Adverse Events, Change in Disease Activity, Movement of Oral ABBV-623 and ABBV-992 Tablets in the Body of Adult Participants With B-cell Cancers

B-cell Lymphoma

Israel, Puerto Rico, Turkey
Southwest Oncology Group
Patient-Centered Outcomes Research Institute; National Cancer Institute (NCI)

Completed

S1415CD, Trial Assessing CSF Prescribing Effectiveness and Risk (TrACER) (TrACER)

Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Febrile Neutropenia | Stage 0 Breast Cancer | Stage IV Non-Small Cell Lung Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast... and other conditions

United States, Puerto Rico
Herlev Hospital
University of Copenhagen; Association of Danish Physiotherapists

Active, not recruiting

The Effect of Aerobic Exercise in Patients With Lacunar Stroke (HITPALS)

Stroke, Lacunar

Denmark
Babes-Bolyai University
The Executive Agency for Higher Education, Research, Development and Innovation...

Completed

Intervention in a Small-scale Study of Game Based Cognitive Change Skills

Emotion Regulation

Romania
University of Miami
United States Department of Defense

Completed

Mindfulness Training for Small Teams

Cognitive Change

United States
Indiana University

Completed

Immunological Profile Changes In Patients With Advanced Non-Small Cell Lung Cancer

Healthy | Non Small Cell Lung Cancer | Non Small Cell Lung Cancer Metastatic

United States
University of Utah
Genzyme, a Sanofi Company

Completed

Pre-Clinical White Matter Changes and Associated Connectivity Effects in Fabry Disease

Fabry Disease

United States
Inter-American Development Bank
Hospital Infantil de Mexico Federico Gomez; The PepsiCo Foundation

Withdrawn

SPOON: Sustained Program for Improving Nutrition - Mexico

Obesity, Childhood | Stunting | Feeding Patterns | Exclusive Breastfeeding

Mexico
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Megestrol in Treating Patients Who Are Undergoing Radiation Therapy for Lung Cancer

Anorexia | Lung Cancer | Cachexia

United States
Heidelberg University
PD Dr. Henrik Watz, Pulmonary Research Center, LungenClinic Großhansdorf... and other collaborators

Active, not recruiting

Change in Airway Peripheral Tone in COPD (CAPTO-COPD)

COPD | COPD, Early-Onset

Germany
Groupe d'Etude Therapeutique des Affections Inflammatoires...

Active, not recruiting

Role of Capsule Endoscopy in the Evaluation of Mucosal Changes During Treatment of Patients With Active Crohn's Disease (CHANCE)

Crohn's Disease

Spain, France
University of Pennsylvania

Terminated

Serial [18F]Thymidine (FLT)PET/CT as a Biomarker of Response in Pemetrexed Therapy for Non-Small Cell Lung Cancer

Non-small Cell Lung Cancer | Starting Pemetrexed Based Therapy | Unresectable Cancer

United States
University of South Florida
American College of Clinical Pharmacy

Completed

Shared Medical Appointments for Weight Loss (SMALL)

Obesity

United States
Chiara Rafanelli

Completed

Promoting Weight Loss and Stress Reduction in Overweight and Obese Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Overweight and Obesity

Italy
University of California, Los Angeles
American Heart Association

Terminated

Remote Preconditioning Over Time To Empower Cerebral Tissue (REM-PROTECT)

Ischemic Stroke | Cognitive Decline | Cerebral Small Vessel Disease

United States
University of Colorado, Denver

Completed

Fit After Baby: Increasing Postpartum Weight Loss in Women at Increased Risk for Cardiometabolic Disease (FAB)

Cardiovascular Diseases | Diabetes | Preterm Birth | Overweight and Obesity | Preeclampsia | Gestational Diabetes | Small for Gestational Age at Delivery | Gestational Hypertension

United States
University of Avignon

Completed

Microcirculatory Vasomotor Changes in Type 2 Diabetes With Peripheral Neuropathy (NEUROMICRO)

Vasodilation | Vasoconstriction | Diabetic Neuropathy Peripheral | Small Vessel Disease of Diabetes Mellitus

France
GTx

Completed

Effect of GTx-024 on Muscle Wasting in Patients With Non-Small Cell Lung Cancer (NSCLC) on First Line Platinum

Non-Small Cell Lung Cancer | Muscle Wasting

United States
Zhujiang Hospital
Wuhan University; First Affiliated Hospital, Sun Yat-Sen University; Sun Yat-Sen... and other collaborators

Unknown

Clinical Observation for the Therapeutic Effect of mNGF on Cognitive Decline in Cerebral Small Vessel Disease

Cerebral Small Vessel Diseases

China
Hams Hamed Abdelrahman

Completed

Change in Mandibular Bone Width Using Two Stages Splitting Approach

Narrow Mandibular Ridge

Egypt
University of British Columbia

Unknown

Integrating Small Changes and Positive Psychology to Improve Treatment Readiness: A Weight Loss Trial (INSPIRE)

Obesity

Canada
CSL Behring

Completed

Safety, Efficacy and Pharmacokinetics of ALD518 in Patients With Non-Small Cell Lung Cancer-related Fatigue and Cachexia

Fatigue | NSCLC | Cachexia

Canada, Australia, Russian Federation, Georgia, Serbia, India, New Zealand, Poland, Romania
Swansea University

Completed

The Effect of Small Changes in Hydration on Cognition

Cognition | Hydration

United Kingdom
Allan Kember
Grand Challenges Canada; Korle-Bu Teaching Hospital, Accra, Ghana; Innovative... and other collaborators

Completed

Ghana PrenaBelt Trial: A Positional Therapy Device to Reduce Still-Birth

Sleep | Pregnancy | Fetal Growth Retardation | Infant, Very Low Birth Weight | Stillbirth | Infant, Small for Gestational Age | Fetal Hypoxia | Infant, Low Birth Weight

Ghana
Allan Kember
University of Michigan; Nova Scotia Health Authority; Grand Challenges Canada; Harvard... and other collaborators

Completed

Halifax PrenaBelt Trial

Sleep | Pregnancy | Fetal Growth Retardation | Infant, Very Low Birth Weight | Stillbirth | Infant, Small for Gestational Age | Fetal Hypoxia | Infant, Low Birth Weight

Canada
IWK Health Centre
University of Michigan; Dalhousie University; Innovative Canadians for Change; University... and other collaborators

Completed

KBTH-GIRHL Healthy Birth Weight Study: A Cross-Section (KBTH-HBWS)

Sleep | Pregnancy | Fetal Growth Retardation | Infant, Very Low Birth Weight | Infant, Small for Gestational Age | Infant, Low Birth Weight

Ghana
Peking University People's Hospital
National Natural Science Foundation of China

Completed

Dynamic Changes of Circulating Tumor DNA in Surgical Lung Cancer Patients

Carcinoma | Lung Neoplasms | Non-small-cell Lung Cancer

China
Oslo University Hospital
Diakonhjemmet Hospital; Lovisenberg Diakonale Hospital

Terminated

Nutritional Problems and Changes in Body Composition in Patients With Non-small Cell Lung Cancer (LEKS) (LEKS)

Weight Loss | Cachexia

Norway
Heat Biologics

Terminated

A Phase 2 Study of Viagenpumatucel-L (HS-110) in Patients With Non-Small Cell Lung Cancer

Non Small Cell Lung Cancer

United States
Wake Forest University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Study of Novel Approaches for Prevention (SNAP)

Weight Gain

United States
M.D. Anderson Cancer Center

Completed

Pilot Study of Hyperthermic Peritoneal Perfusion (HIPEC) for Adolescent and Young Adults With Desmoplastic Small Round Cell Tumor

Sarcoma | Advanced Cancers

United States
International Group of Endovascular Oncology
Azienda Sanitaria Ospedaliera

Unknown

Observational Study With Metronomic Oral Vinorelbine in Elderly Patients With Locally Advanced / Metastatic Non-small-cell Lung Cancer (NSCLC) (VINORELBINA)

Locally Advanced/ Metastatic NSCLC

Italy
Aalborg University Hospital

Completed

Multimodal Intervention for Patients With Non-small Cell Lung Cancer

Cachexia; Cancer

Denmark
Chugai Pharma France
French College of General Hospital Pneumologists (CPHG); French-Speaking Association... and other collaborators

Completed

Non-interventional Study to Assess the Frequency of Cachexia in Patients With Non-small Cell Lung Cancer. (CacheMire)

Cachexia | Non-small Cell Lung Cancer

France
Rush University Medical Center

Completed

A Small Changes Weight Loss Program and Message Dissemination Via Facebook in Chicago's West Side

Obesity

United States
University of Maryland, Baltimore
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Challenge! Adolescent Obesity Prevention (Challenge)

Obesity | Overweight

United States
University of California, San Diego

Withdrawn

Cymbalta for Fibromyalgia Pain - Predictive Value of Small Fiber Changed

Fibromyalgia

United States
Azienda Ospedaliero-Universitaria Careggi
Ministero della Salute, Italy

Completed

Rehabilitation of Attention in Patients With MCI and Brain Subcortical Vascular Changes Using the APT-II (RehAtt)

Mild Cognitive Impairment

Italy
Swiss Group for Clinical Cancer Research

Completed

E-MOSAIC Electronic Tool to Monitor Symptoms

Cancer

Switzerland
Jonathan Kiev
Exatherm, Inc

Completed

Perfusion-Induced Hyperthermia for Metastatic Carcinoma

Solid Tumor, Adult | Metastatic Non-Small Cell Lung Carcinoma

United States
Mayo Clinic

Completed

Change in Permeability of the Small Intestine After Treatment With Gluten

Gastrointestinal Disorders

United States
National Institute of Nutrition, Vietnam
Ryerson University; International Development Research Centre, Canada; Global...

Completed

Scaling up Small-Scale Food Processing to Promote Food Security Among Women Farmers in Rural Vietnam

Anemia | Food Insecurity | Wasting | Stunting | Underweight
Queen's University

Completed

Evaluating a Small Change Approach to Preventing Long Term Weight Gain in Overweight and Obese Adults

Obesity | Prevention of Weight Gain

Canada
Wake Forest University Health Sciences
National Cancer Institute (NCI); Guardant Health, Inc.

Completed

Changes in Circulating Tumor-Specific DNA in Patients With Non-Metastatic Non-Small Cell Lung Cancer

Non Small Cell Lung Cancer

United States
National Cancer Institute (NCI)

Terminated

Azacitidine and Entinostat Before Chemotherapy in Treating Patients With Advanced Non-small Cell Lung Cancer

Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Recurrent Non-Small Cell Lung Carcinoma | Stage IV Non-Small Cell Lung Cancer

United States
University of British Columbia

Unknown

Small Steps for Big Changes: A Lifestyle Program to Reduce the Risk of Developing Type 2 Diabetes

PreDiabetes

Canada

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