Search clinical trials for: tyrosine kinase inhibitors,

Total 65208 results

Johnson & Johnson Pharmaceutical Research & Development...
Janssen Pharmaceutica N.V., Belgium

Completed

A Safety and Dose-finding Study of JNJ-26483327, a Drug in Development for Cancer, for Patients With Advanced and/or Refractory Solid Malignancies.

Pharmacokinetics | Advanced Malignancies | Solid Malignancies | Protein Kinase Inhibitors | Maximum Tolerated Dose | Antineoplastic Protocols | Clinical Trial, Phase 1
Kurume University

Unknown

Metabolic and Cardiovascular Effects of Dipeptidyl Peptidase-4 (DPP-4) or Sodium-glucose Co-transporter Type 2 (SGLT2) Inhibitors

Effects of the DPP-4 Inhibitors or SGLT2 Inhibitors on the Protective Actions for Diabetic Complications

Japan
Pfizer

Completed

Tofacitinib In Psoriatic Arthritis Subjects With Inadequate Response to TNF Inhibitors (OPAL BEYOND)

Psoriatic Arthritis

United States, Belgium, Spain, Taiwan, Australia, Brazil, Czechia, France, Germany, Mexico, Poland, Russian Federation, Slovakia, United Kingdom
Second Affiliated Hospital of Guangzhou Medical...

Recruiting

Infusion of PD1/PDL1 Inhibitor Via Hepatic Arterial Versus Vein for Immunotherapy of Advanced Hepatocellular Carcinoma

Liver Cancer

China
Bloodworks
United States Department of Defense

Active, not recruiting

Reversal of Aspirin Antiplatelet Therapy With Cold Stored Platelets (RASP)

Reversal of Platelet Aggregation Inhibitors

United States
Peking Union Medical College Hospital

Recruiting

Efficacy and Safety of Rapamycin (Sirolimus) in the Treatment of Symptomatic Uterine Fibroids and Leiomyomatosis

Uterine Fibroids

China
Sohag University

Not yet recruiting

Comparative Study of Janus Kinase (JAK) Inhibitors Vs Tumor Necrosis Factor (TNF) Inhibitors in Rheumatoid Arthritis

Rheumatoid Arthritis
Fudan University

Active, not recruiting

Real-world Experience of ICIs Plus Chemotherapy for Advanced ESCC.

Metastatic Esophageal Squamous Cell Carcinoma

China
Erasmus Medical Center

Completed

Angiogenesis Inhibitors and Hypertension: Clinical Aspects

Hypertension

Netherlands
Hadassah Medical Organization

Completed

A Study to Examine the Effect of Reconval K1 Cream to Prevent Skin Toxicity From EGFRI (EGFRI)

Rash Due to Epidermal Growth Factor Receptor Inhibitors
AstraZeneca

Completed

Survey Examining the Frequency and Severity of Acid Related Symptoms While Taking Nexium

Proton Pump Inhibitors | Gastric Acid Suppression

Albania
Vyne Therapeutics Inc.

Completed

Safety, Tolerability and Efficacy Study of Doxycycline Foam for the Prevention of EGFRI Skin Toxicity in Cancer Patients

Rash Due to Epidermal Growth Factor Receptor Inhibitors

Israel
AstraZeneca
Hutchinson MediPharma (HMP)

Active, not recruiting

Savolitinib vs. Sunitinib in MET-driven PRCC.

Kidney Neoplasms | Carcinoma, Renal Cell | Urologic Neoplasms | Neoplasms by Site | Kidney Diseases | Carcinoma | Enzyme Inhibitors | Protein Kinase Inhibitors

United States, Italy, France, Korea, Republic of, Brazil, Russian Federation, Ukraine
Catherine Buettner
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

Clinical Trial of CoQ10 for Mild-to-Moderate Statin-Associated Muscle Symptoms

Pain | Weakness | HMG COA Reductase Inhibitor Adverse Reaction | Cramps | Myalgia or Myositis Nos

United States
Chinese Academy of Sciences
Guangdong Academy of Medical Sciences; West China Hospital; Shanghai Pulmonary...

Unknown

Therapeutic Resistance Prediction of Tyrosine Kinase Inhibitors

Non-small Cell Lung Cancer

China
Scripps Health

Withdrawn

Muscle Characteristics Associated With Statin Therapy

Myopathy | Hydroxymethylglutaryl-CoA Reductase Inhibitors

United States
University of Padova
University Hospital Padova

Recruiting

Correct Timing of Head Imaging in Trauma (CT-HIT)

Craniocerebral Trauma | Platelet Aggregation Inhibitors

Italy
Assiut University

Not yet recruiting

Synergistic Effect of Plasmid Inhibitors and Antimicrobial Drugs Against Clinical MDR-hvKP

Synergy Between Plasmid Inhibitors and Combined Antibiotics
University of Wisconsin, Madison

Completed

Campath-1H Induction to Allow Discontinuation of Calcineurin Inhibitors After Renal Transplantation

Primary Renal Transplant

United States
Adel A.Gomaa

Not yet recruiting

Efficacy of JAK STAT Pathways Inhibitors in Treatment of Patients With Rheumatoid Arthritis

Rheumatoid Arthritis
Rhode Island Hospital
Brown University

Recruiting

Biomarkers For Immune Checkpoint Inhibitors

Neoplasms | Advanced Cancer

United States
Chiang Mai University

Unknown

Effects of Renin-Angiotensin System Inhibitors in Peritoneal Dialysis Patients

Peritoneal Dialysis

Thailand
Qingdao Central Hospital

Recruiting

Tyrosine Kinase Inhibitors in Metastastic Adenoid Cystic Carcinoma

Carcinoma, Adenoid Cystic

China
Sun Yat-sen University

Not yet recruiting

Study of Cadonilimab (AK104) Plus Lenvatinib in Patients With Advanced Endometrial Cancer

Endometrial Cancer | Endometrial Adenocarcinoma

China
University Medical Center Groningen

Terminated

Side Effects of Vascular Endothelial Growth Factor (VEGF) and Epidermal Growth Factor Receptor (EGFR) Directed Therapy (Mabtornib)

Metastatic Malignancies

Netherlands
Duke University

Terminated

ACE-Inhibitor Effects on Total Hip and Knee Arthroplasty Patients

Hypotension | Adverse Effects of Angiotensin-converting-enzyme Inhibitors

United States
Hospital Clínico Universitario de Valladolid

Active, not recruiting

Renin-angiotensin System Blockade Benefits in Clinical Evolution and Ventricular Remodeling After Transcatheter Aortic Valve Implantation (RASTAVI) (RASTAVI)

Angiotensin-Converting Enzyme Inhibitors | Transcatheter Aortic Valve Replacemen

Spain
Hartford Hospital
National Heart, Lung, and Blood Institute (NHLBI)

Completed

The Effect of Statin Medications on Muscle Performance (The STOMP Study) (STOMP)

Muscular Diseases | Hydroxymethylglutaryl-CoA Reductase Inhibitors

United States
Sun Yat-sen University
Guangdong Provincial Hospital of Traditional Chinese Medicine; Guangdong Provincial...

Active, not recruiting

PD-1 Inhibitors Combined With VEGF Inhibitors for Locally Advanced dMMR/MSI-H Colorectal Cancer

Colorectal Cancer | Microsatellite Instability High

China
UNC Lineberger Comprehensive Cancer Center

Completed

Precision Dosing of Tyrosine Kinase Inhibitors in CML Patients

Chronic Myeloid Leukemia | Chronic Myeloid Leukemia, Chronic Phase | CML, Chronic Phase | CML - Philadelphia Chromosome | CML (Chronic Myelogenous Leukemia

United States
Northwell Health

Withdrawn

The Effect of Sodium-Glucose Cotransporter 2 Inhibitors on Advanced Glycation End Products

Diabetes | SGLT-2 Inhibitors | Advanced Glycation End Products
National Cancer Institute (NCI)

Withdrawn

Doxorubicin, CC-(486) (5-azacitidine), Romidepsin, and Duvelisib (hARD) for T-cell Lymphoma

Hepatosplenic T-cell Lymphoma | Enteropathy-Associated T-Cell Lymphoma | Adult T-cell Leukemia/Lymphoma | Extranodal NK-/T-cell Lymphoma, Nasal Type | Monomorphic Epiteliotrophic Intestinal T-cell Lymphoma

United States
Radboud University Medical Center
Dutch Cancer Society

Completed

Effect of Sorafenib on ccRCC Uptake of Radiolabeled Bevacizumab or cG250

Clear Cell Renal Cell Carcinoma

Netherlands
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Evaluation of Skin Health and QoL in Pts Receiving Anti-PD1/PDL1/CTLA4 or CDK Inhibitors. (SkinHealth)

Melanoma | Kidney Cancer | Breast Cancer | Gastric Cancer | Lung Cancer | Bladder Cancer | Skin Cancer | Head Neck Cancer

Italy
Versailles Hospital

Unknown

A Study for Tyrosine Kinase Inhibitors Discontinuation (A-STIM)

Leukemia

France
Versailles Hospital
University Hospital, Bordeaux; Maisonneuve-Rosemont Hospital

Completed

OPTIM DASATINIB (Optimized Tyrosine Kinase Inhibitors Monotherapy) (OPTIM-DASA)

Chronic Myelogenous Leukemia, BCR/ABL Positive

France, Canada
University of Colorado, Denver
Cancer League of Colorado

Completed

Temodar Plus Tyrosine Kinase Inhibitors for Progressive CNS Disease

Non Small Cell Lung Cancer | CNS Progression

United States
Central South University

Recruiting

Hepatotoxicity Related to Protein Kinase Inhibitors

Cancer

China
Sebastian Videla
Institut d'Investigació Biomèdica de Bellvitge; Institut Català de la Salut

Active, not recruiting

ANGIOTENSIN AGENTS AND REDUCTION OF THE PRESCRIPTION OF ANTIDEPRESSANT DRUGS: A RETROSPECTIVE COHORT STUDY USING REAL-WORLD DATA

Depression | Hypertension | ACE Inhibitors | ARB

Spain
Sohag University

Completed

First-time Usage of SGLT2 Inhibitors in Type 2 Diabetic Patients Who Are Fasting During Ramadan: Safety and Efficacy

Type2 Diabetes | SGLT2 Inhibitors, First Time Use | Fasting in Ramadan

Egypt
Assiut University

Active, not recruiting

Effects of Tyrosine Kinase Inhibitors on Liver Enzymes and Electrolytes

Patients Diagnosed as Chronic Meyloid Leukemia

Egypt
Catholic University of the Sacred Heart

Completed

Fecal Microbiota Transplantation in Diarrhea Induced by Tyrosine-kinase Inhibitors

Renal Cell Cancer | Diarrhea Caused by Drug (Disorder)

Italy
Novo Nordisk A/S

Active, not recruiting

Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia With Inhibitors (explorer7)

Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

Spain, Korea, Republic of, India, Australia, United Kingdom, Russian Federation, Poland, Ukraine, Thailand, Mexico, United States, Turkey, Japan, South Africa, Serbia, France, Croatia, Denmark, Algeria, Bulgaria, Malaysia, Portugal, Slovaki... and more
rEVO Biologics
Laboratoire français de Fractionnement et de Biotechnologies

Completed

Phase III Study of Coagulation FVIIa (Recombinant) in Congenital Hemophilia A or B Patients With Inhibitors

Hemophilia A With Inhibitors | Hemophilia B With Inhibitors

United States, Bulgaria, Poland, Russian Federation, Belarus, Georgia, Israel, Romania, Ukraine, United Kingdom
Kasr El Aini Hospital

Completed

SGLT Inhibitors Versus DDP4 Inhibitors and Prostate in Patient With Diabetes

Diabetes Mellitus | Prostatic Hyperplasia

Egypt
Chang Gung Memorial Hospital
National Taiwan University Hospital; Chiayi Christian Hospital; Tainan Sin-lau...

Recruiting

Pioglitazone and SGLT2 Inhibitors vs. DPP4 Inhibitors in Patients With Stroke

Stroke | Diabetes Mellitus

Taiwan
Istituto Clinico Humanitas

Unknown

Tyrosine Kinase Inhibitors In Metastatic Non Small Cell Lung Cancer

Non Small Cell Lung Cancer

Italy
Sun Jia

Completed

Effect of Dapagliflozin on Body Weight in Overweight Women Consuming Different Proportions of Carbohydrate Diet.

Overweight | Carbohydrate | Sodium-glucose Transporter 2 Inhibitors

China
Maastricht University Medical Center

Unknown

Management and Outcomes of Anti-thrombotic Medication Use in Thrombocytopenia (MATTER)

Hematologic Neoplasms | Thrombocytopenia | Anticoagulants | Platelet Aggregation Inhibitors

Netherlands, Italy, Israel, United States
Tatyasaheb Kore Dental College

Completed

EFFECT OF SELECTIVE COX-2 INHIBITOR (ETORICOXIB) ALONG WITH SCALING AND ROOT PLANING (SRP) ON CLINICAL PARAMETERS AND SALIVARY LEVEL OF SUPEROXIDE DISMUTASE IN CHRONIC GENERALIZED PERIODONTITIS A DOUBLE-BLIND, PLACEBO-CONTROLLED, DOUBLE-MASKED RANDOMIZED CONTROLLED TRIAL (RCT).

Periodontitis | Saliva | Cyclooxygenase Two Inhibitors | Etoricoxib | Superoxide Dismutase

India

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