Search clinical trials for: anxiety,

Total 10301 results

Tang-Du Hospital

Unknown

Effects of Dexmedetomidine on Postoperative Cognitive Dysfunction During One-lung Ventilation in Elder Patients

Postoperative Confusion
University of Arkansas

Completed

Drug Discrimination in Methadone-Maintained Humans Study 1 (OMDD1)

Drug Dependence

United States
AstraZeneca

Completed

Drug Interaction Study Between AZD3480 and Cytochrome P450 (Cocktail)

Alzheimer's Disease | Metabolism

Sweden
University of Iowa

Recruiting

Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion

Delirium | Spinal Fusion | Pain, Back | Thoracolumbar Interfascial Plane Block

United States
University Health Network, Toronto

Recruiting

Pharmacological Mechanisms of Low-intensity Focused Ultrasound for Motor Cortex Neuroplasticity (LIFUS-Pharma)

Low Intensity Focussed Ultrasound

Canada
University Hospital, Ghent

Completed

Multimodal Versus Opioid aNalgesia in carDiAc Surgery (MONDAY)

Postoperative Pain | Postoperative Delirium

Belgium
Novartis Pharmaceuticals
Medicines for Malaria Venture

Completed

Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and Dolutegravir

Malaria

United Kingdom
Weill Medical College of Cornell University
M.D. Anderson Cancer Center; Massachusetts General Hospital; Genentech, Inc.

Completed

Study of Venetoclax Plus DA-EPOCH-R for the Treatment of Aggressive B-Cell Lymphomas (V+DA-EPOCH-R)

Diffuse Large B-Cell Lymphoma | High Grade B-Cell Lymphoma

United States
Umeå University

Completed

PECS-2 for Breast Surgery

Anesthesia Morbidity | Breast Neoplasm Female | Anesthesia | Regional Anesthesia Morbidity | Regional Anesthesia

Sweden
Takeda

Withdrawn

Phase 4, Vedolizumab-4002 Post-marketing, Disease-Drug-Drug Interaction Study

Crohn Disease | Colitis, Ulcerative

United States
Andrew A Herring
University of California, Los Angeles; Oregon Health and Science University

Unknown

US-guided SAPB for Rib Fractures in the ED

Rib Fractures | Rib Fracture Multiple

United States
National Cancer Institute (NCI)

Completed

Primary Chemotherapy With Docetaxel-Capecitabine and Doxorubicin-Cyclophosphamide in Breast Cancer

Breast Cancer | Breast Neoplasm

United States
University of Milano Bicocca
Azienda Ospedaliera Universitaria Integrata Verona; Azienda Socio Sanitaria... and other collaborators

Recruiting

Dual Anti-glutamate Therapy in Super-refractory Status Epilepticus After Cardiac Arrest (SUPER-CAT)

Cardiac Arrest | Status Epilepticus

Italy
Susanna Naggie, MD
Vanderbilt University Medical Center; National Center for Advancing Translational...

Active, not recruiting

ACTIV-6: COVID-19 Study of Repurposed Medications

Covid19

United States
Mirati Therapeutics Inc.

Completed

PK Study to Assess Drug-drug Interaction and QTc Between Sitravatinib and a Cocktail of Substrates

Advanced Solid Tumor

United States
Amgen

Active, not recruiting

Study to Investigate the Effect of Rocatinlimab (AMG 451) on the Pharmacokinetics of Multiple Cytochrome P450 (CYP450) Substrates in Participants With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

United States
Case Comprehensive Cancer Center

Active, not recruiting

Perioperative Analgesia on Postoperative Opioid Usage and Pain Control in H&N Cancer Surgery

Opioid Consumption | Postoperative Pain Control

United States
GlaxoSmithKline

Completed

Drug-drug Interaction Study of Gepotidacin

Infections, Bacterial

United States
Novartis Pharmaceuticals

Withdrawn

HDM201 Added to CT in R/R or Newly Diagnosed AML

Leukemia, Myeloid, Acute
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of Ibrutinib on the Pharmacokinetics of Oral Contraceptives, CYP2B6, and CYP3A4 Substrates in Female Participants With B Cell Malignancy

Leukemia, Lymphocytic, Chronic, B-Cell

Spain, Poland
HTL-Strefa S.A.

Completed

Characteristics of Different Types of Safety Lancets on Blood Volume and Perceived Pain in Male and Female Volunteers

Healthy

Poland
Bristol-Myers Squibb

Completed

A Study to Assess the Effect of BMS-986142 on Pharmacokinetics (PK) of Probe Substrates

Rheumatoid Arthritis

United States
Fen Li

Unknown

Predictability Studies on the Efficacy of TNF-α Inhibitors in Chinese RA From "Real World"

Rheumatoid Arthritis
Boehringer Ingelheim

Completed

The Effect of BI 187004 on the Pharmacokinetics of Cytochrome P450 Substrates (Caffeine, Warfarin, Omeprazole, Metoprolol and Midazolam) and a P Glycoprotein Substrate (Digoxin)

Healthy

Germany
AstraZeneca

Completed

A Phase I Study in Healthy Volunteers to Assess the Effect of Cytochrome3A4 (CYP3A4) Inhibitors (Diltiazem and Itraconazole) on the Pharmacokinetics (PK) of AZD3293 and the Effects of AZD3293 on the Pharmacokinetics of Midazolam, a Cytochrome 3A4 and Cytochrome 3A5 (CYP3A4/CYP3A5) Substrate (AZD3293DDI)

Healthy Volunteers | Pharmacologic Action

United States
First Affiliated Hospital of Chongqing Medical...
Southwest Hospital, China; Central South University; The Second Affiliated Hospital... and other collaborators

Recruiting

Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD) (STAR-AD)

Depression | Sequestra

China
Henry Ford Health System

Recruiting

Nonopioid Analgesia After Labral Surgery

Narcotic Use

United States
Henry Ford Health System

Completed

Nonopioid Analgesia After Rotator Cuff Repair

Rotator Cuff Tear

United States
zr Pharma & GmbH

Completed

Pharmacokinetic Drug-Drug Interaction Study of Rucaparib (DDI)

Neoplasms

Poland
Henry Ford Health System

Completed

Nonopioid Analgesia After Anterior Cruciate Ligament Reconstruction

Anterior Cruciate Ligament Injury

United States
New York State Psychiatric Institute
National Institute of Mental Health (NIMH)

Completed

Treatment of Adolescent Suicide Attempters (TASA)

Depression | Suicide, Attempted

United States
St. Petersburg Bekhterev Research Psychoneurological...

Completed

Pregabalin for Opiate Withdrawal Syndrome

Opioid Withdrawal

Russian Federation
The First Affiliated Hospital of Dalian Medical...
Nanfang Hospital of Southern Medical University; Beijing Anzhen Hospital; First...

Completed

The Success of Opening Single CTO Lesions to Improve Myocardial Viability Study (SOS-comedy)

Hibernation, Myocardial | Complete Occlusion of Coronary Artery
Eli Lilly and Company

Completed

A Study of Ixekizumab in Participants With Plaque Psoriasis

Psoriasis

United States
Bristol-Myers Squibb

Completed

Study to Evaluate Effect of Belatacept on Pharmacokinetics of Inje Cocktail in Healthy Volunteers

Transplant Rejection

United States
Aga Khan University

Recruiting

Analgesic Efficacy of Ropivacaine Alone or in Combination With Adjuvants on Post-operative Analgesia Following Video-Assisted Thoracoscopic Surgery.

Postoperative Analgesia

Pakistan
Henry Ford Health System

Completed

Nonopioid Analgesia After Arthroscopic Meniscus Surgery

Narcotic Use | Meniscus Disorder

United States
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC

Completed

Aprepitant's Effect on Drug Metabolism in Multi-Day Combination (CHOP/R-CHOP) Chemotherapy Regimen in Lymphoma Patients

Lymphoma

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Adjuvant Stage 2-3A Breast Cancer With Positive Lymph Nodes

Breast Cancer

United States
GlaxoSmithKline

Completed

Drug Interaction Study of Darunavir/Ritonavir and Lopinavir/Ritonavir on GSK2248761 PK and CYP450 Probe Drugs

Healthy Subjects | Infection, Human Immunodeficiency Virus

United States
Bristol-Myers Squibb

Completed

Drug Interaction Study With a Potential Alzheimer's Disease Compound

Alzheimer Disease

United States
University of Missouri-Columbia
National Library of Medicine (NLM)

Completed

Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow

Depression | HIV Infections | Hypertension | Obesity | Diabetes Mellitus | Back Pain | Urinary Incontinence | Irritable Bowel Syndrome | Insomnia | Asthma | Anxiety | Sinusitis | Shoulder Pain | Allergic Rhinitis | Urinary Tract Infection | Vaginitis | Bursitis | Hyperlipidemia | Esophageal Reflux | Benign Prostatic Hypertrophy | Osteoporosis... and other conditions

United States
Children's National Research Institute
National Institute of Nursing Research (NINR); National Institutes of Health... and other collaborators

Active, not recruiting

FACE for Children With Rare Diseases (FACE-Rare)

Rare Diseases

United States
CES University

Recruiting

Essential Hypotension and Allostasis Registry (ESSENTIAL)

Depression | Diabetes Mellitus | Cancer | Atrial Fibrillation | Fibromyalgia | Blood Pressure | Syncope | Coronary Heart Disease | Chronic Fatigue Syndrome | Panic Attack | Diastolic Heart Failure | POTS | Systolic Heart Failure | Vasovagal Syncope | Acute Myocardial Infarction (AMI) | Transient Ischemic Attack (TIA) | Acute... and other conditions

Colombia
The University of Texas Health Science Center,...
National Center for Advancing Translational Sciences (NCATS)

Completed

MAST Trial: Multi-modal Analgesic Strategies in Trauma (MAST)

Nonspecific Pain Post Traumatic Injury

United States
Loma Linda University

Terminated

Liposomal Bupivacaine in Implant Based Breast Reconstruction

Breast Cancer | Postoperative Pain

United States
Theodor Bilharz Research Institute

Completed

Dexmedetomidine and Desflurane Consumption

Anesthesia

Egypt
Boehringer Ingelheim

Completed

Study to Evaluate the Effect of Multiple Doses of BIRT 2584 XX Tablets on the Pharmacokinetic Parameters of Warfarin, Omeprazole, Caffeine, and Dextromethorphan in Healthy Male Volunteers

Healthy
Celgene

Completed

Study Evaluating the Effects of Food, Cytochrome P450 Inhibition and Induction on the Pharmacokinetics of CC-122

Healthy Volunteer

United States
Sanofi

Completed

Combination of Cabazitaxel With Prednisolone With Primary Prophylaxis With PEG-G-CSF in Treatment of Patients With Prostate Cancer (PEGAZUS)

Prostate Cancer

Japan

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