Clinical Trials Sponsored by Trio Medicines Ltd.

Total 1074 results

Wuxi Hisky Medical Technology Co Ltd
Guangzhou First People's Hospital; Ruijin Hospital; Xinhua Hospital, Shanghai... and other collaborators

Unknown

Comparison of Acoustic Attenuation Parameter Using FibroTouch With Liver Biopsy for Diagnosis of Hepatic Steatosis

Fatty Liver | Hepatic Steatosis | Liver Steatosis

China
GeneScience Pharmaceuticals Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; Affiliated Hospital... and other collaborators

Unknown

A Study of PEG-somatropin Injection to Treat Children of Turner Syndrome

Turner Syndrome

China
GeneScience Pharmaceuticals Co., Ltd.
Peking University First Hospital; Peking Union Medical College Hospital; Children... and other collaborators

Unknown

A Study to Evaluate the Efficacy and Safety of Recombinant Human Growth Hormone Injection in Patients With Prader-Willi Syndrome

Prader-Willi Syndrome

China
Genetron Health
Cancer Institute and Hospital, Chinese Academy of Medical Sciences; Henan Cancer... and other collaborators

Completed

Clinical Evaluation of Genetron Lung Cancer Panel in Non-small Cell Lung Cancer Patients

Non-Small Cell Lung Cancer

China
Second Military Medical University
Zhejiang Cancer Hospital; Changhai Hospital; First People's Hospital of Hangzhou and other collaborators

Unknown

Trial of Antigen Pulsed Dendritic Cells (APDC) in Metastatic Colorectal Cancer

Metastatic Colorectal Cancer
Zhejiang University
First People's Hospital of Hangzhou; Second Affiliated Hospital, School of... and other collaborators

Recruiting

Decitabine+Cladribine+Cytarabine+Granulocyte Colony-stimulating Factor (D-CLAG) for Relapsed or Refractory Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia

China
Children's Hospital of Philadelphia
Eli Lilly and Company; University of Pennsylvania; Takeda; National Institute of... and other collaborators

Recruiting

The Myelin Disorders Biorepository Project (MDBP)

Mucopolysaccharidoses | Leukoencephalopathies | Leukodystrophy | Adrenoleukodystrophy | Adrenomyeloneuropathy | X-linked Adrenoleukodystrophy | Gangliosidoses | Metachromatic Leukodystrophy | Krabbe Disease | Refsum Disease | Cadasil | Sjogren-Larsson Syndrome | Allan-Herndon-Dudley Syndrome | White Matter Disease | GM2... and other conditions

United States
Dr Ian B Wilkinson
University College London Hospitals; Imperial College London; Newcastle University and other collaborators

Recruiting

Optimising Azithromycin Prevention Treatment in COPD to Reduce Exacerbations (OPACE)

Chronic Obstructive Pulmonary Disease

United Kingdom
University of Sao Paulo General Hospital
Samsung Eletrônica da Amazônia Ltda; Academic Research Organization of Instituto...

Recruiting

Assessment of Smartwatch SAMSUNG to Monitor Sleep Quality: an Observational Prospective Study - SleepEx2 Protocol (SLEEP-EX2)

Insomnia | Sleep Initiation and Maintenance Disorders | Sleep | Health Status | Wearable Electronic Devices

Brazil
Maastricht University
Aristotle University Of Thessaloniki; P1vital Products LTD.; Biotrial; University... and other collaborators

Completed

Validating Reward-related Biomarkers (RTOC) (RTOC)

Depression | Schizophrenia | Motivation | Anhedonia, Physical | Anhedonia, Social | Negative Symptoms With Primary Psychotic Disorder

Germany, Greece, Netherlands, Spain
The First Affiliated Hospital of Soochow University
The First Affiliated Hospital with Nanjing Medical University; The Affiliated... and other collaborators

Recruiting

Sequential Infusion of CD19 and BCMA CAR-T Cells to Improve PTR in Patients With AL

Platelet Transfusion Refractoriness | Acute Leukemia in Remission

China
Sixth Affiliated Hospital, Sun Yat-sen University
Wuhan University; First Affiliated Hospital of Fujian Medical University; Xiyuan... and other collaborators

Unknown

TSTstarr + for Treatment of Severe Prolapsed Hemorrhoids --- a Multi-center Randomized Controlled Clinical Trail

Hemorrhoids
Peijia Medical Technology (Suzhou) Co., Ltd.
General Hospital of Shenyang Military Region; West China Hospital; Second Affiliated... and other collaborators

Active, not recruiting

Safety and Efficacy of TaurusOne® Transcatheter Aortic Valve System in Patients With Severe Calcific Aortic Stenosis

Aortic Stenosis

China
MRC/UVRI and LSHTM Uganda Research Unit
London School of Hygiene and Tropical Medicine; Assistance Publique - Hôpitaux... and other collaborators

Not yet recruiting

Implementing Oral (Event-driven and Daily) and Long-acting Pre-Exposure Prophylaxis in Mobile Men in Sub-Saharan Africa (MOBILEMEN)

HIV
GeneScience Pharmaceuticals Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; Tongji Hospital and other collaborators

Active, not recruiting

A Study Extension Period of PEG-somatropin (Pegylated-somatropin) in the Treatment of Children With Idiopathic Short Stature

Dwarfism

China
GeneScience Pharmaceuticals Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; Tongji Hospital and other collaborators

Unknown

A Study of PEG-somatropin in the Treatment of Children With Idiopathic Short Stature

Dwarfism

China
Peijia Medical Technology (Suzhou) Co., Ltd.
General Hospital of Shenyang Military Region; Shanghai Zhongshan Hospital; China... and other collaborators

Completed

Safety and Efficacy of TaurusOne® Transcatheter Aortic Valve Replacement System With Retrievable Delivery Catheter System

Aortic Stenosis

China
Institute for Clinical and Experimental Medicine
Brno University Hospital; Tomas Bata Hospital, Czech Republic; Masaryk Hospital... and other collaborators

Completed

Colorectal Cancer: Screening vs. Non-Screening (CRC)

Colorectal Cancer | Screening

Czechia
Eastern Hepatobiliary Surgery Hospital
Sun Yat-sen University; Shanghai Zhongshan Hospital; First Affiliated Hospital... and other collaborators

Unknown

Effect of Babaodan on Tumor Recurrence After Curative Resection of Hepatocellular Carcinoma

Hepatocellular Carcinoma | Tumor Recurrence
The New York Academy of Medicine
Johns Hopkins University; University of Miami; Yale University; Brown University; Montefiore Medical Center and other collaborators

Unknown

Buprenorphine and Integrated HIV Care Evaluation

HIV Infections | Opioid-Related Disorders | AIDS

United States
Centers for Disease Control and Prevention
Education Development Center, Inc.; California State University, Long Beach; Sentient... and other collaborators

Completed

A Waiting Room-Delivered Video to Enhance Clinical Outcomes Among Persons Living With HIV (TCOM)

HIV Infections
Beijing Pins Medical Co., Ltd
Wuhan University; Beijing Tiantan Hospital; West China Hospital; Tianjin Medical... and other collaborators

Recruiting

Effectiveness and Safety of Directional Deep Brain Stimulation for Parkinson's Disease

Parkinson's Disease

China
Air Force Military Medical University, China
The People's Hospital of Hebei Province; Bethune International Peace Hospital; Second Hospital of Jilin University and other collaborators

Unknown

Impact of Benfluorex Versus Metformin on Glucose Control and Insulin Secretion in Chinese Type 2 Diabetic Patients

Type 2 Diabetes

China
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Completed

Pragmatic Clinical Trial for a More Effective Concise and Less Toxic MDR-TB Treatment Regimen(s) (TB-PRACTECAL)

Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa, Uzbekistan
GeneScience Pharmaceuticals Co., Ltd.
Peking University First Hospital; Shengjing Hospital; The First Affiliated Hospital... and other collaborators

Unknown

A Study to Evaluate the Efficacy and Safety of Recombinant Human Growth Hormone in Short Stature Children Due to Chronic Kidney Disease Before Transplantation

Dwarfism

China
Shanghai Jiao Tong University School of Medicine
Guangzhou Psychiatric Hospital; The First Affiliated Hospital of Zhengzhou... and other collaborators

Recruiting

Decreasing Risk of Psychosis by Sulforaphane (DROPS Trial)

Clinical High Risk Syndrome of Psychosis

China
University College, London
London School of Hygiene and Tropical Medicine; MRC/UVRI and LSHTM Uganda Research... and other collaborators

Active, not recruiting

Long-Acting Treatment in Adolescents (LATA) (LATA)

HIV Infections | Hiv | HIV-1-infection | Paediatric Human Immunodeficiency Virus Infection

Uganda, Zimbabwe, Kenya, South Africa
University of Alberta
Alberta Health & Wellness; Merck Frosst Canada Ltd.; Canadian Diabetes Association and other collaborators

Completed

Improving Blood Pressure Management in Patients With Diabetes (SCRIP-HTN)

Hypertension | Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1

Canada
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Active, not recruiting

PRACTECAL-PKPD Sub Study (PRACTECAL-PKPD)

Multi-drug Resistant Tuberculosis | Pulmonary Tuberculosis | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa
The First Affiliated Hospital of Soochow University
The First Affiliated Hospital with Nanjing Medical University; Jiangsu Province... and other collaborators

Recruiting

Study of BiRd Regimen Combined With BCMA CAR T-cell Therapy in Newly Diagnosed Multiple Myeloma (MM) Patients

Multiple Myeloma

China
CARsgen Therapeutics Co., Ltd.
Xiangya Hospital of Central South University; Peking University People's Hospital and other collaborators

Active, not recruiting

Clinical Trial to Evaluate CT053 in Patients With Relapsed and/or Refractory Multiple Myeloma (LUMMICAR STUDY 1)

Multiple Myeloma

China
University of Leeds
GlaxoSmithKline; AstraZeneca; Sanofi Pasteur, a Sanofi Company; BioMérieux; Da Volterra and other collaborators

Completed

COMBACTE-CDI Understanding the Burden of C. Difficile Infection (COMBACTE-CDI)

Clostridium Difficile Infection

United Kingdom
Wuxi Hisky Medical Technology Co Ltd
Zhongda Hospital, Medical School, Southeast University; Suzhou Municipal Hospital and other collaborators

Recruiting

Prevalence of MAFLD in Patients With Type 2 Diabetes in Jiangsu Province of China

Type 2 Diabetes Mellitus in Remission | Metabolic Associated Fatty Liver Disease

China
University of North Carolina, Chapel Hill
London School of Hygiene and Tropical Medicine; Shandong University; National... and other collaborators

Completed

A Non-inferiority Randomized Controlled Trial to Evaluate Promoting Condom Use Among MSM and Transgender Individuals in China

Sexually Transmitted Diseases | Human Immunodeficiency Virus

China
Louise Kenny
Erasmus Medical Center; University of Liverpool; Copenhagen Trial Unit, Center... and other collaborators

Unknown

IMproved PRegnancy Outcome by Early Detection (IMPROvED)

Pregnancy Complications | Pregnancy | Pre-eclampsia | Pregnancy, High-risk

Ireland, Netherlands, Sweden, United Kingdom
Chunxiu Gong
The First Affiliated Hospital with Nanjing Medical University; Tongji Hospital and other collaborators

Not yet recruiting

Genetic Diagnosis and Human Growth Hormone Treatment in Small for Gestational Age Children With Short Stature

Genetic Diseases, Inborn | Small for Gestational Age Infant | Silver-Russell Syndrome
University of Pennsylvania
The Hospital for Sick Children; Mayo Clinic; National University Hospital, Singapore and other collaborators

Active, not recruiting

Osteochondritis Dissecans of Knee Prospective Cohort

Osteochondritis Dissecans

United States
GeneScience Pharmaceuticals Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; The First Affiliated... and other collaborators

Unknown

Clinical Study of Recombinant Human Follitropin for Injection Assisted in COH Assisted IVF-ET

Ovarian Hyperstimulation Syndrome

China
GeneScience Pharmaceuticals Co., Ltd.
Peking University First Hospital; Peking Union Medical College Hospital; The... and other collaborators

Unknown

A Non-inferiority Phase 2 Study to Evaluate the Safety and Efficacy of PEG-rhGH in the Treatment of AGHD

Adult Growth Hormone Deficiency

China
GeneScience Pharmaceuticals Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; First Affiliated... and other collaborators

Unknown

Efficacy and Safety of rhGH (Jintropin®) in Pediatric Participants With ISS

Dwarfism

China
Seoul National University Hospital
Seoul National University Bundang Hospital; Second Affiliated Hospital, School... and other collaborators

Recruiting

Impact of Coronary CT Angiography, Physiologic Assessment and Pharmacotherapy on the Clinical Outcomes (PRIME-CT)

Coronary Artery Disease

Korea, Republic of
GeneScience Pharmaceuticals Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; Tongji Hospital and other collaborators

Unknown

A Study of Gentuximab + Paclitaxel in Patients With Advanced Gastric or Gastroesophageal Junction Cancer

Advanced Gastric or Gastroesophageal Junction Cancer

China
Michael Hoelscher
German Federal Ministry of Education and Research; ANRS, Emerging Infectious... and other collaborators

Completed

A Trial to Confirm a Sustained Virological Suppression Defined as HIV-RNA <50 Copies/ml of 3 Different Doses of Fozivudine in Context to a Standard Zidovudine Based Antiretroviral Therapy Regimen (FATI-01)

HIV-1 Infection

Côte D'Ivoire, Tanzania
Wits Health Consortium (Pty) Ltd
Fred Hutchinson Cancer Center; Janssen Vaccines & Prevention B.V.; Right to Care and other collaborators

Recruiting

Sisonke 2 - A COVID-19 Vaccine Boost Open Label Study. (Sisonke Boost)

SARS CoV 2 Infection

South Africa
Jiangsu Famous Medical Technology Co., Ltd.
Zhejiang Cancer Hospital; Shanxi Province Cancer Hospital; Jiangsu Province Hospital... and other collaborators

Not yet recruiting

Integrated Chinese and Western Medicine Specialized Disease Cohort for Colorectal Cancer

Colorectal Cancer | Colorectal Adenoma
National Centre for AIDs and STD Control, Nepal
Karolinska Institutet; B.P. Koirala Institute of Health Sciences; Tribhuvan University... and other collaborators

Completed

Package of Care to Improve Retention in ART and Mortality Among Treatment Naive HIV Infected Individuals (PRAN)

HIV

Nepal
West China Hospital
Sun Yat-sen University; Peking University Cancer Hospital & Institute; Second... and other collaborators

Recruiting

Comparison of the Pathological Effect Between 2 and 4 Cycles Neoadjuvant CAPOX for Low/Intermediate Risk II/III Rectal Cancer (COPEC)

Rectal Cancer | Neoadjuvant Chemotherapy

China
Hangzhou Jiuyuan Gene Engineering Co. Ltd.,
The First Affiliated Hospital with Nanjing Medical University; Cancer Institute... and other collaborators

Unknown

Saftey and Efficacy of Pegfilgrastim in Preventing Chrmotherapy-induced Neutropenia (PEG-rhG-CSF)

Neutropenia

China
Ministry of Health, Brazil
Hospital de Clinicas de Porto Alegre; Instituto de Cardiologia do Rio Grande... and other collaborators

Terminated

Cell Therapy in Myocardial Infarction (EMRTCC)

Acute Myocardial Infarction

Brazil
University of Sao Paulo General Hospital
Hospital Israelita Albert Einstein; Instituto Dante Pazzanese de Cardiologia; Beneficência Portuguesa de São Paulo and other collaborators

Completed

The REPLICCAR Registry and The Statewide Quality Improvement Initiative (REPLICCAR)

Cardiac Surgical Procedures

Brazil

Clinical Trials Sponsored by Trio Medicines Ltd.

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