Clinical Trials Sponsored by Eight28, LLC

Total 10745 results

Weill Medical College of Cornell University
National Cancer Institute (NCI); Merck Sharp & Dohme LLC; University of Sao Paulo and other collaborators

Active, not recruiting

Nine-valent HPV Vaccine to Prevent Persistent Oral HPV Infection in Men Living With HIV

HPV Infection | HIV-1-infection | HPV Positive Oropharyngeal Squamous Cell Carcinoma

Brazil, Mexico, Puerto Rico
Memorial Sloan Kettering Cancer Center
M.D. Anderson Cancer Center; University of California, Los Angeles; University... and other collaborators

Active, not recruiting

Pembrolizumab (MK-3475) in Patients With Recurrent Malignant Glioma With a Hypermutator Phenotype

Glioma | Recurrent Malignant Glioma

United States
Centre Hospitalier Saint Joseph Saint Luc de Lyon
RESCUe - RESeau Cardiologie Urgence / RESUVal - RESeau des Urgences de la...

Unknown

Epidemiology of Suspected Epileptic Seizures (EPI-lepsie)

Epilepsy

France
University Hospital, Essen
Bristol-Myers Squibb; Merck Sharp & Dohme LLC; Gilead Sciences; Boehringer Ingelheim and other collaborators

Completed

Cardiovascular Diseases in HIV-infected Patients HIV-HEART Study: 7.5 Years Follow-up

Heart Failure | Metabolic Syndrome | HIV | Coronary Heart Disease | AIDS

Germany
Fundación Academia Española de Dermatología
Bristol-Myers Squibb; Eli Lilly and Company; UCB Pharma; Merck Sharp & Dohme LLC; Novarti... and other collaborators

Recruiting

Spanish Registry of Systemic Treatments in Psoriasis (Biobadaderm)

Psoriasis

Spain
R-Pharm
Data Management 365; Exacte Labs LLC; Federal State Budgetary Institution "NMIC... and other collaborators

Active, not recruiting

Study Comparing the Pharmacokinetics, Safety, and Efficacy of RPH-075 and Keytruda® in Patients With Malignant Neoplasms

Head and Neck Squamous Cell Carcinoma | Skin Melanoma | Squamous Non-small-cell Lung Cancer

Russian Federation
Biologics & Biosimilars Collective Intelligence...
Merck Sharp & Dohme LLC; Pfizer; AbbVie; University of Pittsburgh; Boehringer Ingelheim and other collaborators

Completed

Incidence of Hospitalizations for Serious Infections in Patients Receiving Biologic Anti-Inflammatories for Rheumatologic, Psoriatic, and Gastrointestinal Conditions: A Descriptive Analysis

Rheumatoid Arthritis | Psoriasis | Psoriatic Arthritis | Inflammatory Bowel Disease | Ankylosing Spondylitis
Wayne State University
Universiti Putra Malaysia; National Kidney Foundation; Ministry of Health, Malaysia and other collaborators

Completed

Palm Tocotrienols in Chronic Hemodialysis (USA) (PATCH)

End Stage Renal Disease | Chronic Kidney Disease

United States
Genetron Health
Peking University First Hospital; Xiangya Hospital of Central South University and other collaborators

Enrolling by invitation

Detection Evaluation of a Novel Blood-based DNA Methylation Assay in Early-stage Hepatocellular Carcinoma Patients

Liver Cancer

China
Yale University
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH); University of California, San Francisco and other collaborators

Not yet recruiting

Office-based Methadone Versus Buprenorphine to Address Retention in Medication for Opioid Use Disorder Treatment.

Opioid Use Disorder

United States
Biologics & Biosimilars Collective Intelligence...
Merck Sharp & Dohme LLC; Pfizer; AbbVie; University of Pittsburgh; Boehringer Ingelheim and other collaborators

Completed

Descriptive Analysis of Long- and Intermediate-Acting Insulin in Adult Diabetics

Diabetes
AstraZeneca
Contract Research Organization: USA; PAREXEL Early Phase Clinical Unit Baltimore and other collaborators

Completed

A Study to Assess the Effect of Intensive Uric Acid (UA) Lowering Therapy With RDEA3170, Febuxostat, Dapagliflozin on Urinary Excretion of UA

Asymptomatic Hyperuricemia

United States
University Hospital, Essen
Bristol-Myers Squibb; GlaxoSmithKline; Merck Sharp & Dohme LLC; Boehringer Ingelheim and other collaborators

Completed

Cardiovascular Diseases in HIV-infected Patients HIV-HEART Study: 5 Years Follow-up

Heart Failure | Metabolic Syndrome | HIV | Coronary Heart Disease | AIDS

Germany
Santalis Pharmaceuticals, Inc.
Derm Research, PLLC; ClinDatrix, Inc.; Clinical Trials of Texas, Inc.; Progressive... and other collaborators

Completed

A Trial of a Botanical Drug (EISO) for Treatment of Mild-to-Moderate Plaque Psoriasis

Plaque Psoriasis

United States
Erasme University Hospital
AZ Sint-Jan AV; Cliniques universitaires Saint-Luc- Université Catholique de... and other collaborators

Completed

PAtient-PHYsician Relationship Assessment (PAPHYRA)

Hepatocellular Carcinoma

Belgium
University Hospital St Luc, Brussels
Université Catholique de Louvain; University of Applied Sciences of Western... and other collaborators

Completed

In Vitro Assessment of a Breath-synchronized Vibrating Mesh Nebulizer During Non Invasive Ventilation (Synchro-Neb)

Lung Diseases | Asthma | Cystic Fibrosis | COPD | Respiratory Diseases

Belgium
University Hospital, Geneva
University of Lausanne Hospitals; University Hospital St Luc, Brussels; University... and other collaborators

Completed

Neurally Adjusted Ventilatory Assist for Non Invasive Ventilation and Patient-ventilator Interaction

Non Invasive Ventilation | Patient Ventilator Interaction

Belgium, Switzerland
Cliniques universitaires Saint-Luc- Université...
Grand Hôpital de Charleroi; Université de Liège; Clinique Saint-Jean, Bruxelles; Clinique Saint Pierre Ottignies

Not yet recruiting

PoCUS Diagnostic Accuracy for Fecal Impaction in the Emergency Department: A Prospective Study (FICUS)

Fecal Impaction of Colon
Invex Therapeutics Ltd.
Premier Research Group plc; University Hospitals Birmingham Neuro Ophthalmology... and other collaborators

Terminated

A Trial to Determine the Efficacy and Safety of Presendin in IIH (IIH EVOLVE)

Idiopathic Intracranial Hypertension

Israel, Germany, Australia, United States, United Kingdom, New Zealand
Hartford Hospital
Merck Sharp & Dohme LLC; University of Texas Southwestern Medical Center; University... and other collaborators

Recruiting

Imipenem/Cilastatin/Relebactam Pharmacokinetics, Safety, and Outcomes in Adults and Adolescents With Cystic Fibrosis

Pneumonia, Bacterial | Cystic Fibrosis

United States
Brigham and Women's Hospital
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Active, not recruiting

Vitamin D and Omega-3 Trial (VITAL) (VITAL)

Cardiovascular Disease | Cancer

United States
Hospital de Manises
Merck Sharp & Dohme LLC; Hospital Arnau de Vilanova; Hospital Universitario La... and other collaborators

Unknown

Optimization of Golimumab Treatment in Ulcerative Colitis

Colitis, Ulcerative

Spain
Universitaire Ziekenhuizen KU Leuven
Centre Hospitalier Universitaire de Liege; CHC MontLégia; Belgian Health Care... and other collaborators

Recruiting

Immediate Versus Optional Delayed Surgical Repair for Treatment of Acute ACL Injuries (IODA)

ACL Injury

Belgium
Universitaire Ziekenhuizen KU Leuven
Cliniques universitaires Saint-Luc- Université Catholique de Louvain; GZA Ziekenhuizen... and other collaborators

Recruiting

Conservative Endometrioma Surgery (BLAST)

Endometrioma | Endometriosis Ovary

Belgium
Université Catholique de Louvain
Centre Hospitalier Universitaire Vaudois; Cliniques universitaires Saint-Luc-... and other collaborators

Unknown

Testing Interference-based Methods to Mitigate Gambling Craving - A Multiple Single Case Design

Craving | Gambling | Gambling Disorder | Gambling, Pathological | Gambling Problem

Switzerland
Centers for Disease Control and Prevention
Washington University School of Medicine; The Miriam Hospital; Hennepin Healthcare... and other collaborators

Completed

Study to Understand the Natural History of HIV/AIDS in the Era of Effective Therapy (SUN Study)

HIV Infections | Sexually Transmitted Diseases

United States
Universitaire Ziekenhuizen KU Leuven
University Hospital, Ghent; Academisch Medisch Centrum - Universiteit van Amsterdam... and other collaborators

Unknown

Prospective Study Investigating the Role of Occupational Exposure on Sinus Surgery Outcome

Rhinosinusitis
University Hospital, Ghent
Universitaire Ziekenhuizen KU Leuven; University Hospital, Antwerp; Cliniques... and other collaborators

Recruiting

Serum GLYcomics to Predict Graft Loss and Mortality After Liver Transplantation (GLYGALT)

Liver Transplant Failure | Prognostic Biomarkers

Belgium
Université de Sherbrooke
Centre de recherche du Centre hospitalier universitaire de Sherbrooke; Interdisciplinary... and other collaborators

Enrolling by invitation

Pelvic Floor Muscle Training for Women With Myotonic Dystrophy

Urinary Incontinence | Myotonic Dystrophy Type 1

Canada
Mesoblast International Sàrl
University of Southern California; OrthoIndy; TRIA Orthopaedic Center; Midwest... and other collaborators

Completed

A Phase I/II Study of Chondrogen Delivered by Intra-Articular Injection Following Meniscectomy

Recovery Following Partial Medial Meniscectomy

United States
Sensor Technology for Deafblind
Deaf-Blind Support Foundation Con-nection; Federal State Budgetary Institution... and other collaborators

Completed

Clinical and Genetic Testing of Patients With Usher Syndrome

Retinitis Pigmentosa | Usher Syndrome | Congenital Deafness

Russian Federation
Johns Hopkins University
Medical University of South Carolina; Vanderbilt University Medical Center; University... and other collaborators

Recruiting

Gravity Versus Vacuum Based Indwelling Tunneled Pleural Drainage System (NEWTON)

Pleural Effusion

United States, United Kingdom
Institute of Tropical Medicine, Belgium
KU Leuven; Institut National de Recherche Biomédicale. Kinshasa, République... and other collaborators

Completed

Treating Non-typhoidal Salmonella Bloodstream Infections in Children Under Five in DR Congo: a Cohort Study (TreNTS)

Blood-stream Infections | Salmonella Infection Non-Typhoid

Congo, The Democratic Republic of the
Cliniques universitaires Saint-Luc- Université...
Cliniques Universitaires UCL de Mont-Godinne, Dr Joseph Kerger; Cliniques Saint-Pierre...

Unknown

Panitumumab (Vectibix®) in Cutaneous Squamous Cell Carcinoma (SCC) (PASCE)

Carcinoma, Squamous Cell

Belgium
AIO-Studien-gGmbH
Bristol-Myers Squibb; Eli Lilly and Company; Merck Sharp & Dohme LLC; Pfizer; Gilead... and other collaborators

Recruiting

Clinical Research Platform Into Molecular Testing, Treatment and Outcome of (Non-)Small Cell Lung Carcinoma Patients (CRISP)

Small-cell Lung Cancer | Non-small Cell Lung Cancer Metastatic | Non-small Cell Lung Cancer Stage I | Metastatic Non-small Cell Lung Cancer (NSCLC) | Non Small Cell Lung Cancer Stage III | Non-small Cell Lung Cancer Stage II

Germany
Icahn School of Medicine at Mount Sinai
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University... and other collaborators

Completed

Medication Adherence in Children Who Had a Liver Transplant (MALT)

Pediatric Recipients of a Liver Transplant

United States
State University of New York at Buffalo
Children's Hospital of Philadelphia; University of Pennsylvania; United States... and other collaborators

Not yet recruiting

Exercise Reset for Concussion in a Military Environment

Brain Concussion
Yale University
Baylor College of Medicine; University of Chicago; Columbia University; Brown University and other collaborators

Recruiting

SCOPE-CLI: Shifting Care and Outcomes for Patients With Endangered Limbs (SCOPE-CLI)

Peripheral Arterial Disease

United States
Sensor Technology for Deafblind
Central Clinical Hospital under President Affairs; Deaf-Blind Support Foundation... and other collaborators

Completed

Prospective Open Clinical and Genetic Study of Patients With Retinitis Pigmentosa (RU-RP)

Retinitis Pigmentosa | Usher Syndromes

Russian Federation
Université de Sherbrooke
Canadian Institutes of Health Research (CIHR); Western University, Canada; Agence...

Completed

Patient-Centred Innovations for Persons With Multimorbidity - Quebec (PACEinMM-QC)

Depression | Heart Failure | Stroke | Hypertension | Cardiovascular Disease | Diabetes | Ulcer | Cancer | Arthritis | Rheumatoid Arthritis | Musculoskeletal Pain | Asthma | Gastroesophageal Reflux | Dementia | Anxiety | HIV | Crohn's Disease | Osteoporosis | Ulcerative Colitis | Chronic Obstructive Pulmonary Disease (COPD) | Hyperlipi... and other conditions

Canada
Santalis Pharmaceuticals, Inc.
Derm Research, PLLC; ClinDatrix, Inc.; Texas Dermatology and Laser Specialists; Clinical Trials of Texas, Inc... and other collaborators

Completed

A Trial of a Botanical Drug Containing East Indian Sandalwood Oil (EISO) For Treatment of Atopic Dermatitis

Eczema | Atopic Dermatitis

United States
Yih-Ing Hser
National Institute on Drug Abuse (NIDA); University of California, Los Angeles and other collaborators

Not yet recruiting

Extended-release Buprenorphine Compared to Sublingual Buprenorphine in Rural Settings (RXR) (RXR)

Substance-Related Disorders | Opioid-Related Disorders | Narcotic-Related Disorders

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and Postpartum

HIV Infections | Tuberculosis

United States, Malawi, Puerto Rico, South Africa, Thailand, Zimbabwe, Brazil, Kenya, Uganda, India, Tanzania, Botswana
The Netherlands Cancer Institute
Bristol-Myers Squibb; Eli Lilly and Company; Bayer; GlaxoSmithKline; Merck Sharp... and other collaborators

Recruiting

The Drug Rediscovery Protocol (DRUP Trial) (DRUP)

Cancer | Neoplasm | Tumors | Neoplasia

Netherlands
QOL Medical, LLC
Johns Hopkins University; Massachusetts General Hospital; Baylor College of Medicine and other collaborators

Completed

Congenital Sucrase-Isomaltase Deficiency (CSID) Genetic Prevalence Study (GPS) (CSID GPS)

Congenital Sucrase-isomaltase Deficiency (CSID)

United States
University of Liege
Universitaire Ziekenhuizen KU Leuven; University Hospital, Ghent; University... and other collaborators

Recruiting

Value of Negative 18FDG PET/CT in Milan Out, Up-to-seven in, HCC Transplant Candidates

Hepatocellular Carcinoma

Belgium
Loc Cong Dai Tran, MD
University of Medicine and Pharmacy at Ho Chi Minh City

Completed

The Change in Cutaneous Temperature When Using Acupuncture at TB-3 and BL-65 Acupoints in Healthy Participants

Healthy Participants

Vietnam
Jules Bordet Institute
Cliniques universitaires Saint-Luc- Université Catholique de Louvain; Universiteit... and other collaborators

Completed

Sorafenib Plus Capecitabine Efficacy Assessment in Patients With Advanced Pre-treated Colorectal Cancer (SoMore)

Colorectal Cancer

Belgium
GRADE Study Group
Bristol-Myers Squibb; National Institute of Diabetes and Digestive and Kidney... and other collaborators

Completed

A Comparative Effectiveness Study of Major Glycemia-lowering Medications for Treatment of Type 2 Diabetes (GRADE)

Type 2 Diabetes | Comparative Effectiveness of Glycemia-lowering Medications

United States
Abbott Medical Devices
KU Leuven; Thoratec Corporation; Cliniques universitaires Saint-Luc- Université... and other collaborators

Completed

BeneMACS Study:HeartMate 2 (HM2)Left Ventricular Assist Device (LVAD) Survival in Non Transplant Patients is Equal/Better Than Results in Medical Literature (BeneMACs)

Heart Failure

Belgium

Clinical Trials Sponsored by Eight28, LLC

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Myanmar

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations