Search clinical trials for: Clinical Trial, Phase 1

Total 107948 results

National Center for Research Resources (NCRR)
Northwestern University

Completed

Phase II/III Randomized, Double-Blind, Placebo-Controlled Study of Dehydroepiandrosterone in Women With Mild to Moderate Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Janssen, LP

Completed

A Study of Itraconazole in the Prevention of Histoplasmosis, a Fungal Infection, in HIV-Infected Patients

HIV Infections | Histoplasmosis

United States
Pfizer

Completed

A Study to Evaluate the Safety and Efficacy of Azithromycin in Individual Patients With Serious Nontuberculous Mycobacterial Disease Who Are Failing or Intolerant of Other Available Therapy

HIV Infections | Mycobacterium Avium-Intracellulare Infection | Tuberculosis, Mycobacterium Infection

United States
Glaxo Wellcome

Completed

A Study of 1592U89 Combined With Other Anti-HIV Drugs in Patients Who Have Taken Anti-HIV Drugs

HIV Infections

United States
Northwestern University

Completed

A Randomized, Placebo-Controlled Study of the Safety and Efficacy of Efavirenz, Didanosine, and Stavudine in Combination With or Without Hydroxyurea in Antiretroviral Naive or Experienced HIV-Infected Patients

HIV Infections

United States
Merck Sharp & Dohme LLC

Completed

A Study to Compare the Effectiveness of Two Anti-HIV Drug Combinations

HIV Infections

United States
National Center for Research Resources (NCRR)
University of Texas

Completed

Phase I/II Study of Heme Arginate and Tin Mesoporphyrin for Acute Porphyria

Porphyria
Dana-Farber Cancer Institute

Unknown

Phase I Study of Amifostine in Patients With Bone Marrow Failure Related to Fanconi's Anemia

Fanconi's Anemia

United States
Glaxo Wellcome

Completed

The Antiviral Efficacy of Concurrent Zidovudine and 2',3'-Dideoxyinosine or 2',3'-Dideoxycytidine in Patients With Human Immunodeficiency Virus Disease

HIV Infections

United States, Puerto Rico, Australia
Mallinckrodt

Completed

The Therakos UVAR Photopheresis System in the Treatment of AIDS-Related Complex

HIV Infections

United States
Interferon Sciences

Completed

Double-Blind, Randomized, Dose Ranging Study of Alferon LDO (Low Dose Oral Interferon Alfa-n3 (Human Leukocyte Derived)) in HIV+ Subjects

HIV Infections

United States
Glaxo Wellcome

Completed

Retrovir Capsules in the Treatment of HIV-Infected Patients in Renal Failure

HIV Infections | Kidney Failure, Chronic

United States
Fisons

Completed

A Double-Blind Group Comparative Study To Evaluate the Long-Term Safety and Effectiveness of Two Different Doses of Aerosol Pentamidine in the Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients With Multiple Episodes of PCP

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Hoffmann-La Roche

Completed

Open-Label Program of Dideoxycytidine ( ddC ) to Be Used in Combination With Zidovudine ( AZT ) for Treatment of Advanced HIV Disease

HIV Infections

United States
Glaxo Wellcome

Completed

A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients

HIV Infections | Herpes Simplex

United States
Parke-Davis

Completed

A Study of CI-1012 in HIV-Infected Patients

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of a Combination of Four Drugs in Patients With Recent HIV Infection

HIV Infections

United States
Merck Sharp & Dohme LLC

Unknown

Safety and Effectiveness of an Anti-HIV Drug Combination Taken Twice Daily

HIV Infections

United States
ICN Pharmaceuticals

Terminated

The Safety and Effectiveness of Ribavirin in the Early Stages of HIV-Infection

HIV Infections
Hoffmann-La Roche

Completed

The Safety and Effectiveness of Ganciclovir Plus Interferon Beta in Preventing the Return of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States
Hoffmann-La Roche

Completed

A Comparison of Saquinavir Hard- and Soft-Gelatin Capsules in HIV-Infected Patients

HIV Infections

United States
Weill Medical College of Cornell University

Completed

A Study of Three Drug Combination Therapies in HIV-Infected Patients Who Have Never Been Treated With Anti-HIV Drugs

HIV Infections

United States
Gilead Sciences

Completed

Safety and Effectiveness of Adding PMPA Prodrug to an Anti-HIV Drug Combination to Treat HIV-Infected Patients

HIV Infections

United States
Gilead Sciences
Glaxo Wellcome; Dupont Applied Biosciences

Completed

Safety and Effectiveness of Giving Adefovir Dipivoxil Plus Abacavir Plus Efavirenz Plus Amprenavir to HIV-Infected Patients Who Have Failed to Respond to Previous Protease Inhibitor Treatment

HIV Infections

United States
Hoffmann-La Roche

Completed

A Study to Compare the Effects of Two Anti-HIV Drug Combinations on the Immune Systems of HIV-Infected Patients

HIV Infections

United States
National Center for Research Resources (NCRR)
University of Pennsylvania

Completed

Phase I Study of the Third Generation Adenovirus H5.001CBCFTR in Patients With Cystic Fibrosis

Cystic Fibrosis
Steinhart Medical Associates

Unknown

Treatment of Advanced AIDS Patients With Dextrin Sulfate

HIV Infections

United States
Merck Sharp & Dohme LLC

Completed

A Study of the Side Effects of L-743,872 in Men With Candidal Esophagitis

HIV Infections | Candidiasis, Esophageal

United States
Hoffmann-La Roche

Unknown

Valganciclovir in Patients With CMV Retinitis and AIDS Who Cannot Take Drugs by Injection

HIV Infections | Cytomegalovirus Retinitis

United States, Puerto Rico
U.S. Bioscience

Completed

A Compassionate Treatment Protocol for the Use of Trimetrexate Glucuronate With Leucovorin Protection for Patients With Pneumocystis Carinii Pneumonia.

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Hoffmann-La Roche

Completed

A Study of Zidovudine (AZT) Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected Patients With Little or No Previous Treatment

HIV Infections

United States, Puerto Rico
Glaxo Wellcome

Completed

A Study of 1592U89 and Ethanol When Given Together to HIV-Infected Patients

HIV Infections

United States
Boehringer Ingelheim

Completed

An Open-Label Study in HIV+ Patients to Determine the Effects of Nevirapine (Viramune) on the Pharmacokinetics of Clarithromycin and Activity of Cytochrome 3A4.

HIV Infections

United States
Eunice Kennedy Shriver National Institute of Child...
Children's National Research Institute

Terminated

Phase I Pilot Study of Liver-Directed Gene Therapy for Partial Ornithine Transcarbamylase Deficiency

Ornithine Transcarbamylase Deficiency Disease
National Center for Research Resources (NCRR)
Scripps Clinic

Completed

Phase II Pilot Study of Cladribine (2-Chlorodeoxyadenosine; 2-CdA) for Early Stage Primary Sclerosing Cholangitis

Cholangitis, Sclerosing
Hoffmann-La Roche

Completed

Treatment of Psoriasis Using Acitretin in HIV-Positive Patients

HIV Infections | Psoriasis

United States
Merck Sharp & Dohme LLC

Unknown

Safety and Effectiveness of Giving Indinavir, Ritonavir, Stavudine, and Lamivudine to HIV-Infected Patients Who Have Never Received Anti-HIV Drugs

HIV Infections

United States
Schering-Plough

Completed

Safety and Effectiveness of Fluconazole Versus SCH 56592 to Treat Thrush in HIV-Positive Patients

HIV Infections | Candidiasis, Oral

United States, Barbados
Liposome

Completed

Safety and Efficacy of Amphotericin B Lipid Complex in the Treatment of Cryptococcal Meningitis in Patients With the Acquired Immunodeficiency Syndrome

HIV Infections | Meningitis, Cryptococcal

United States
Novartis

Completed

Safety and Effectiveness of Giving Lamisil to HIV-Positive Subjects With Thrush Who Have Not Responded to Fluconazole Treatment

HIV Infections | Candidiasis, Oral

United States
National Center for Research Resources (NCRR)
University of California, San Diego

Completed

Phase II Pilot Study of Aminoimidazole Carboxamide Riboside (AICAR), a Precursor of Purine Synthesis, for Lesch-Nyhan Disease

Lesch-Nyhan Syndrome
Jacobus Pharmaceutical

Completed

A Comparison of Dapsone and Trimethoprim-Sulfamethoxazole in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Sequus Pharmaceuticals

Completed

A Study of DOX-SL in the Treatment of AIDS-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
Renovis

Unknown

Study of REN-1654 in Patients With Sciatica Pain

Sciatica | Radiculopathy | Herniated Disc

United States
PharmaResearch

Unknown

Comparing Side Effects of Two Forms of Videx in HIV-Infected Adults

HIV Infections

United States
Dupont Merck

Completed

A Study of Efavirenz in Combination With Stavudine and Didanosine

HIV Infections

United States
Hoffmann-La Roche

Completed

The Safety and Effectiveness of Saquinavir Soft Gelatin Capsules Combined With Other Anti-HIV Drugs

HIV Infections

United States
Agouron Pharmaceuticals

Completed

Viracept Expanded Access Program

HIV Infections

United States
Ortho Pharmaceuticals

Completed

A Double-Blind, Placebo-Controlled Study With Open-Label Follow-Up To Determine the Safety and Efficacy of Subcutaneous Doses of r-HuEPO in AIDS Patients With Anemia Induced by Their Disease and AZT Therapy

HIV Infections | Cytopenias

United States
Fairview University Medical Center

Completed

Study of Allogeneic Bone Marrow Transplantation Following Cyclophosphamide and Radiotherapy in Patients With Myelodysplastic Syndrome and Acute Leukemia Related to Fanconi's Anemia

Myelodysplastic Syndromes | Leukemia, Lymphocytic, Acute | Fanconi's Anemia | Leukemia, Nonlymphocytic, Acute

United States

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