Search clinical trials for: IL-1 inhibitors

Total 117111 results

Gilead Sciences

Completed

The Safety and Effectiveness of Cidofovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States, United Kingdom
U.S. Bioscience

Completed

A Compassionate Treatment Protocol for the Use of Trimetrexate Glucuronate (Neutrexin) With Leucovorin Protection for European Adult Patients (>= 13 Years Old) With Pneumocystis Carinii Pneumonia

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Hoffmann-La Roche

Completed

An Open-Label Safety Study of Oral Ganciclovir Maintenance Treatment of CMV Retinitis in People With Limited Venous Access

HIV Infections | Cytomegalovirus Retinitis

United States
Triangle Pharmaceuticals

Completed

A Randomized, Double-Blind Study of MKC-442 Combined With Viracept in Patients Who Are Epivir + Retrovir Experienced and Are Protease Inhibitor- and Non-Nucleoside Reverse Transcriptase Inhibitor-Naive

HIV Infections

United States
Fairview University Medical Center

Unknown

Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Giant Cell Arteritis | Wegener's Granulomatosis | Churg-Strauss Syndrome | Polyarteritis Nodosa | Purpura, Schoenlein-Henoch | Juvenile Rheumatoid Arthritis | Takayasu Arteritis | Pure Red Cell Aplasia | Graft Versus Host Disease | Anemia, Hemolytic, Autoimmune and other conditions

United States
National Institute on Alcohol Abuse and Alcoholism...

Completed

Drug Treatment for Alcoholics With Post-Traumatic Stress Disorder

Alcoholism | Post-Traumatic Stress Disorder

United States
Glaxo Wellcome

Unknown

Safety and Effectiveness of Three Anti-HIV Drugs Combined in One Pill (Trizivir)

HIV Infections

United States
National Center for Research Resources (NCRR)
University of Pittsburgh

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Oral Iloprost for Raynaud's Phenomenon Secondary to Systemic Sclerosis

Systemic Sclerosis | Raynaud Disease
Fairview University Medical Center

Unknown

Pilot Study of Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Life Threatening Hemophagocytic Disorders

Hemophagocytic Lymphohistiocytosis | Graft Versus Host Disease | Chediak-Higashi Syndrome | Virus-Associated Hemophagocytic Syndrome | X-Linked Lymphoproliferative Syndrome | Familial Erythrophagocytic Lymphohistiocytosis

United States
Pfizer

Completed

Pilot Study of Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States
National Center for Research Resources (NCRR)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University...

Completed

Phase III Randomized Study of Ursodiol With Vs Without Methotrexate for Primary Biliary Cirrhosis

Liver Cirrhosis, Biliary
Genelabs Technologies

Completed

A Randomized Phase II Efficacy, Activity and Safety Study of GLQ223 Alone and in Combination With Zidovudine in Symptomatic HIV-Infected Patients Without Prior Treatment With GLQ223 or Trichosanthin

HIV Infections

United States
Schering-Plough

Completed

Phase III Ganciclovir +/- rGM-CSF for AIDS-Related CMV Retinitis

HIV Infections | Cytomegalovirus Retinitis

United States
Janssen Pharmaceuticals

Completed

Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis.

HIV Infections | Candidiasis, Esophageal

United States
Gilead Sciences

Completed

Cidofovir as a Treatment for Herpes Simplex in Patients With AIDS

HIV Infections | Herpes Simplex

United States
Amgen

Completed

An Open-Label Phase I/II Study of Recombinant Granulocyte Colony Stimulating Factor (r-metHuG-CSF) and Recombinant Erythropoietin (rHuEPO) Given Subcutaneously Along With Zidovudine (AZT) to Patients With the Acquired Immune Deficiency Syndrome (AIDS) or Severe AIDS-Related Complex (ARC)

HIV Infections

United States
Lederle Laboratories

Completed

Phase II Study of Intravenous Novantrone(R) in the Treatment of AIDS Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
Janssen, LP

Completed

A Study of Treatments for Fungal Infections of the Mouth and Throat in HIV-Infected Patients Who Have Had Success With Itraconazole But Not With Fluconazole

HIV Infections | Candidiasis, Oral

United States
Merck Sharp & Dohme LLC

Completed

Effect of Indinavir Plus Two Other Anti-HIV Drugs on Blood Clotting in HIV-Positive Males With Hemophilia

HIV Infections | Hemophilia A

Canada, United States
Triangle Pharmaceuticals

Completed

A Study of MKC-442 in Combination With Other Anti-HIV Drugs

HIV Infections

United States
Celgene Corporation

Completed

Compassionate Use Study of Two Dose Levels of Thalidomide in Adults With HIV Wasting Syndrome

HIV Infections | HIV Wasting Syndrome

United States
Celgene Corporation

Completed

D-MPH in the Treatment of Fatigue and Neurobehavioral Function Related to Chemotherapy in Adult Cancer Patients

Neoplasms | Fatigue

United States
American National Red Cross

Completed

A Pilot Study to Obtain Preliminary Information Regarding the Efficacy and Safety of the Combination of Immune Globulin and Ganciclovir as Compared to Ganciclovir Alone in the Treatment of Sight-Threatening CMV Retinitis in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States
St. Vincent's Medical Center

Completed

Depot Disulfiram for AIDS and ARC

HIV Infections

United States
Pharmacia

Completed

A Three-Arm Comparative Trial for the Treatment of MAC Bacteremia in AIDS: A Clarithromycin/Ethambutol Regimen Containing Rifabutin (450 Mg) or Rifabutin (300 Mg) or Placebo

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Gilead Sciences

Completed

A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Adefovir Dipivoxil When Added to Standard Antiretroviral Therapy for the Treatment of HIV-Infected Patients With CD4 Cell Counts >= 200/mm3

HIV Infections

United States
Agouron Pharmaceuticals

Completed

A Study of Viracept in AIDS Patients With Cytomegalovirus Retinitis

HIV Infections | Cytomegalovirus Retinitis

United States
Glaxo Wellcome

Completed

A Comparison of Two Multi-Drug Therapies in HIV-Infected Patients Who Have Never Received Anti-HIV Treatment

HIV Infections

United States
Merck Sharp & Dohme LLC
Agouron Pharmaceuticals

Completed

A Study on the Safety and Effectiveness of Twice-Daily Nelfinavir Plus Twice-Daily Indinavir Plus Efavirenz in HIV-Positive Patients Who Have Never Taken Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) or Protease Inhibitors

HIV Infections

United States
Pharmacia and Upjohn

Completed

A Study to Find the Best Dosing Schedule for Delavirdine, Zidovudine, and Indinavir in HIV-Positive Patients

HIV Infections

United States
Glaxo Wellcome

Completed

The Safety and Effectiveness of Retrovir in HIV-Infected Patients Who Have Problems Related to the Nervous System

HIV Infections

United States
Gilead Sciences

Completed

The Safety and Effectiveness of Bis-POM PMEA in HIV-Infected Patients

HIV Infections

United States
Hoechst Marion Roussel

Completed

The Safety and Effectiveness of HBY 097 Used With or Without AZT in HIV-Infected Patients Who Have Mild or No Symptoms

HIV Infections

United States
Triangle Pharmaceuticals

Suspended

A Comparison of Emtricitabine and Abacavir Used in a Three-Drug Combination in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States
Gilead Sciences

Unknown

The Safety and Effectiveness of PMPA Prodrug in HIV-Infected Patients

HIV Infections

United States
National Center for Research Resources (NCRR)
Northwestern University

Completed

Phase II Randomized Study of Cidofovir for Peripheral Cytomegalovirus Retinitis

Acquired Immunodeficiency Syndrome | Cytomegalovirus Retinitis
National Center for Research Resources (NCRR)
Centers for Disease Control and Prevention

Unknown

Intensive Pharmacokinetics of the Nelfinavir-Rifabutin Interaction in Patients With HIV-Related Tuberculosis Treated With a Rifabutin-Based Regimen

HIV Infections | Tuberculosis

United States
Corixa Corporation

Completed

Safety and Efficacy Study of Iodine-131 Anti-B1 Antibody Plus CHOP For Untreated Mantle Cell Lymphoma

Mantle Cell Lymphoma

United States
Boehringer Ingelheim

Completed

The Safety and Effectiveness of Nevirapine Plus Lamivudine Plus Other Anti-HIV Drugs

HIV Infections

United States
Eunice Kennedy Shriver National Institute of Child...

Unknown

Independent Studies of Dextromethorphan and of Donepezil Hydrochloride for Rett Syndrome

Rett Syndrome

United States
Janssen, LP

Completed

A Randomized, Open, Comparative Multicenter Study of Initial Treatment With Intravenous Itraconazole Versus Amphotericin B Followed by Consolidation Treatment With Itraconazole Capsules in Patients With Blastomycosis or Histoplasmosis

HIV Infections | Histoplasmosis | Blastomycosis

United States
Merck Sharp & Dohme LLC

Completed

A Study of Indinavir Sulfate Given Together With Stavudine to HIV-Positive Patients

HIV Infections

United States
Celgene Corporation

Completed

A Study to Access the Safety/Efficacy of Thalidomide in the Treatment of Anemia in Patients With Myelodysplastic Syndromes

Myelodysplastic Syndromes

United States
National Center for Research Resources (NCRR)

Unknown

Chronic Thalidomide Administration in Patients Undergoing Chemoembolization for Unresectable Hepatocellular Cancer

Liver Cancer

United States
Triangle Pharmaceuticals

Completed

A Study of MKC-442 in HIV-Positive Patients

HIV Infections
Glaxo Wellcome

Completed

The Safety and Effectiveness of 524W91

HIV Infections

United States
National Center for Research Resources (NCRR)
National Institute of Allergy and Infectious Diseases (NIAID); Rockefeller...

Completed

Phase II Placebo Controlled Study of Thalidomide in Patients With Mycobacterial and HIV Infections

HIV Infections | Mycobacterium Infections | Tuberculosis
National Center for Research Resources (NCRR)

Unknown

Kinetics of Response of Cytomegalovirus With Ganciclovir Treatment Using Quantitative Real-Time PCR

Cytomegalovirus Infections

United States
Pfizer

Completed

A Comparison of Fluconazole and Amphotericin B in the Treatment of Fungal Infections

HIV Infections | Mycoses

United States
Yi Yang
Wuzhou Red Cross Hospital; General Hospital of Shenyang Military Region; Chinese... and other collaborators

Recruiting

Stroke Registration of Young Adults in China (REACH)

Ischemic Stroke

China

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