Search clinical trials for: pharmacokinetics (PK)

Total 12041 results

Abbott

Withdrawn

A Dose-Finding Study to Evaluate the Safety, Efficacy and Pharmacokinetics of Adalimumab in Subjects With Refractory Asthma

Asthma
Charite University, Berlin, Germany
Novartis

Completed

Pharmacokinetics of Everolimus and Enteric-Coated Mycophenolatesodium Before and After Withdrawal of Cyclosporine in Renal Transplant Patients

Renal Transplantation

Germany
Northwell Health
The Cleveland Clinic; University of North Carolina

Completed

Pilot Studies of Novel Therapies to Treat Resistant Focal Segmental Glomerulosclerosis (FSGS)

Focal Glomerulosclerosis

United States
HiberCell, Inc.

Completed

Multiple-Dose, Dose-Escalation Safety, Pharmacodynamics, and Pharmacokinetics Study of Imprime PGG™ Injection

Healthy
King Saud University

Completed

Evaluating Pharmacokinetics and Pharmacodynamics of Jusline

Healthy

Saudi Arabia
National Cancer Center, Korea

Unknown

Study of Genetic Polymorphisms of Drug Transporters and Orphan Nuclear Receptors on Treatment Effects of Irinotecan

Colorectal Neoplasms | Secondary

Korea, Republic of
University of Oslo School of Pharmacy

Terminated

Ganciclovir Pharmacokinetics in Patients Undergoing Continuous Renal Replacement Therapy

Acute Renal Failure | Cytomegalovirus Infections | Multi Organ Failure

Norway
Novartis

Completed

Safety, Tolerability, Effect of Vildagliptin and How the Body Changes the Blood Level of Vildagliptin in Healthy Chinese Volunteers

Healthy

China
Novartis
Schering-Plough

Completed

Study of Mometasone Furoate/Formoterol Fumarate Inhalation Combination in Healthy Volunteers

Healthy

United Kingdom
Novartis

Completed

Drug Interaction of SMC021 With Concomitant Antacid (Calcium Carbonate/Magnesium Hydroxide).

Health Postmenopausal Women

Denmark
Novartis

Completed

Effect of Moderate Hepatic Impairment on the Pharmacokinetics and Metabolism of a Single Dose of Licarbazepine

Healthy

Czech Republic
Novartis

Completed

Effect of Food on the Pharmacokinetics of AQW051 in Japanese Healthy Male Subjects

Healthy

Japan
Novartis

Completed

Effect of Severe Renal Impairment on Pharmacokinetics and Metabolism of a Single Administration of Licarbazepine

Healthy

Czech Republic
Novartis

Completed

Study to Explore the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral AHT956 in Healthy Subjects

Healthy

Switzerland
SK Chemicals Co., Ltd.

Completed

Phase I Study to Investigate the Alcohol Interaction of SK3530

Erectile Dysfunction

Korea, Republic of
Novartis

Completed

Evaluation of Pharmacokinetic Interaction of Indacaterol With Ketoconazole in Healthy Adult Subjects

Healthy

India
Nordic Bioscience A/S
Novartis

Completed

Pharmacokinetics/Pharmacodynamics of Oral Salmon Calcitonin in Patients With Osteoarthritis

Osteoarthritis

Denmark
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Effects of DVS SR and Duloxetine on the Pharmacokinetics of Desipramine in Healthy Subjects

Depressive Disorder | Depression | Depressive Disorder, Major

United States
Novartis

Completed

Effects of Water and Food Intake on the Pharmacokinetics and Pharmacodynamics of Oral Salmon Calcitonin in Healthy Postmenopausal Women

Postmenopausal Osteoporosis

Denmark
RFS Pharma, LLC

Completed

Safety, Tolerance, Pharmacokinetic and Antiviral Study of Amdoxovir in Combination With Zidovudine in Adults With HIV

HIV Infections

Argentina
University Hospital, Basel, Switzerland

Completed

Oral Ghrelin Agonist in Healthy Subjects

Healthy Subjects
Tel-Aviv Sourasky Medical Center

Unknown

The Effect of Low Dose Aspirin on the Pharmacokinetics of Methotrexate

Rheumatoid Arthritis
Archemix Corp.

Completed

Safety, Pharmacokinetics, and Pharmacodynamics of ARC1779 in Healthy Volunteers

Thrombosis

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Effects of Multiple Oral Doses of ERB-041 on Cardiac Repolarization in Healthy Subjects

Healthy | Long QT Syndrome

United States
Alizyme

Completed

Study of the Blood Levels and Effects of ATL-962 on Fat Excretion in Obese Subjects

Obesity

United States
National Center for Complementary and Integrative...

Completed

Botanical/Drug Interactions in HIV: Glucuronidation

HIV Seronegativity

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety of Lecozotan SR in Healthy Young and Elderly Subjects

Alzheimer Disease

France
Baxter Healthcare Corporation

Completed

A Crossover Study Assessing the Pharmacokinetics, Pharmacodynamics, and Safety of Recombinant Human Insulin

Healthy

Germany
National Taiwan University Hospital

Unknown

The Effect of Sirolimus on the Pharmacokinetics of Tacrolimus

Kidney Transplantation

Taiwan
Otsuka Frankfurt Research Institute GmbH

Completed

Safety, Efficacy and Pharmacokinetics of OPC-67683 in Patients With Pulmonary Tuberculosis

Pulmonary Tuberculosis

South Africa
Avigen

Completed

Study to Examine the Safety, Tolerability, and Pharmacokinetics of AV650

Healthy Subjects

United States
University of Aarhus

Completed

Pharmacokinetics of Ghrelin

Healthy Subjects

Denmark
Memorial Sloan Kettering Cancer Center

Completed

Safety and Pharmacokinetics of Jin Fu Kang in Comb w/Docetaxel for Patients w/Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

United States
QDose Limited

Unknown

Investigating the Pharmacokinetics and Pharmacodynamics of Recombinant Human Insulin Administered by Dry Powder Inhaler

Diabetes Mellitus

United States
Pfizer

Completed

Safety, Toleration and Pharmacokinetics of Single Intravenous Doses of Peptide YY in Overweight Adults

Obesity

United States
KU Leuven

Completed

Long-Term Pharmacokinetics of Tacrolimus in Renal Recipients

Renal Transplantation

Belgium
Altus Pharmaceuticals

Completed

Study of an Extended-Release, Crystalline Formulation of Recombinant Human Growth Hormone (ALTU-238) in Growth Hormone Deficient Adults to Determine Pharmacokinetics, Pharmacodynamics, and Drug Safety

Adult Growth Hormone Deficiency

United States
Novartis

Completed

Pharmacokinetics and Pharmacodynamics Study of Oral Salmon Calcitonin in Healthy Postmenopausal Women

Postmenopausal Osteoporosis

Denmark
Committee on Chinese Medicine and Pharmacy

Completed

The Pharmacokinetics Study of Concentrated Herbal Formula and Traditional Herbal Decoctions in Humans

Healthy

China
Acusphere

Completed

Phase 1 Safety and Pharmacokinetic Study of AI-700 in Patients With Diminished DLCO and COPD and/or CHF

Chronic Obstructive Pulmonary Disease | Congestive Heart Failure

United States
Astellas Pharma Inc

Completed

A Study to Assess Efficacy, Safety and Pharmacokinetics of a Tacrolimus New Oral Formulation (MR4) in BMT Recipients

Bone Marrow Transplantation | Graft Versus Host Disease | Graft-Versus-Host Disease | Graft-Vs-Host Disease

Japan
DiObex

Completed

A Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Activity of Very Low Dose-Glucagon in Subjects With Type 1 Diabetes Mellitus

Type 1 Diabetes

United States
Centers for Disease Control and Prevention
Malaria Research and Training Center, Bamako, Mali; Liverpool School of Tropical...

Suspended

Chlorproguanil-Dapsone in Pregnant Women

Malaria

Mali
University of Aarhus
Novo Nordisk A/S

Completed

A Comparison of Pharmacodynamics and Pharmacokinetics of Insulin Aspart, Biphasic Insulin Aspart 30, 50 and 70.

Type 1 Diabetes

Denmark
Laboratoires Thea

Completed

Ocular Tolerance, Safety and Ocular Pharmacokinetics After 1 Drop of T1225 0.5, 1.0, 1.5% in 48 Healthy Volunteers

Eye Infections, Bacterial
Laboratoires Thea

Completed

Safety and Ocular Pharmacokinetics After 1 Drop of T1225 0.5, 1 and 1.5% in 48 Healthy Volunteers

Eye Infections, Bacterial

France
Laboratoires Thea

Completed

Ocular Pharmacokinetics After a Single Drop Instillation of T1225 0.5, 1, 1.5% in 91 Healthy Volunteers

Eye Infections, Bacterial
National Cancer Institute (NCI)

Completed

A Phase I Trial of 5-Fluorouracil Given With 776C85 (GW776) and Low-Dose Leucovorin in Adult Patients With Solid Tumors

Neoplasms | Lymphoma

United States
Danish University of Pharmaceutical Sciences

Unknown

Pharmacokinetics and Pharmacodynamics of Buprenorphine in Healthy Volunteers

Healthy Volunteers

Denmark
International Partnership for Microbicides, Inc.

Completed

A Study to Assess the Pharmacokinetics of Dapivirine (TMC120) Vaginal Microbicide Gel

HIV Infections

South Africa

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