Search clinical trials for: observational study

Total 120315 results

National Eye Institute (NEI)

Unknown

The Early Treatment for Retinopathy of Prematurity Study (ETROP)

Retinopathy of Prematurity

United States
National Eye Institute (NEI)

Unknown

The Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study

Myopia

United States
Hoffmann-La Roche

Completed

A Study of Saquinavir and Zalcitabine, Used Alone and Together, in the Treatment of Advanced HIV Infection in Patients Who Stopped Taking or Who Cannot Take Zidovudine

HIV Infections

United States, Puerto Rico, Canada
Hoechst Marion Roussel

Completed

A Randomized, Double-Blind Active-Controlled, Dose-Ranging Study of the Safety and Efficacy of Chronically Administered MDL 28,574A in the Treatment of HIV-Infected Patients

HIV Infections

United States
Gilead Sciences

Completed

Phase I Study of the Safety, Tolerance, and Pharmacokinetics of 9-[2-(Bispivaloyloxymethyl)Phosphonylmethoxyethyl]Adenine (Bis-POM PMEA; Adefovir Dipivoxil) in HIV-Infected Patients

HIV Infections

United States
Shaman Pharmaceuticals

Completed

Double-Blind Placebo-Controlled Study Comparing the Combination of 15% SP-303 Gel With Acyclovir Versus Acyclovir Alone for the Treatment of Recurrent Herpes Simplex Virus (HSV) Infections in Subjects With Acquired Immunodeficiency Syndrome (AIDS)

HIV Infections | Herpes Simplex

United States, Puerto Rico
National Center for Research Resources (NCRR)
Baylor College of Medicine

Completed

Phase IV Study of Chronic Infusional Epoprostenol for Severe Primary Pulmonary Hypertension

Hypertension, Pulmonary
National Center for Research Resources (NCRR)
University of Texas

Completed

Study of Nutritional Factors in Porphyria

Porphyria
National Center for Research Resources (NCRR)

Suspended

A Multi-Centered Study of the Long-Term Effect of Salmeterol and Albuterol in Cystic Fibrosis

Cystic Fibrosis

United States
University of Minnesota

Completed

Phase I/II Study of Total Body Irradiation, Cyclophosphamide, and Fludarabine Followed by Alternate Donor Hematopoietic Cell Transplantation in Patients With Fanconi's Anemia

Fanconi's Anemia

United States
National Center for Research Resources (NCRR)
University of Alabama at Birmingham

Completed

Phase III Randomized Study of Oral Acyclovir in Infants With Herpes Simplex Virus Infection Limited to Skin, Eyes, and Mouth

Herpes Simplex

United States, Canada
National Center for Research Resources (NCRR)
Duke University

Unknown

A Safety and Feasibility Study of Active Immunotherapy in Patients With Metastatic Prostate Carcinoma Using Autologous Dendritic Cells Pulsed With Antigen Encoded in Amplified Autologous Tumor RNA

Prostate Cancer

United States
National Center for Research Resources (NCRR)
Crohn's and Colitis Foundation

Completed

A Pharmacokinetic Study to Determine the Oral Bioavailability of Methotrexate in Patients With Inflammatory Bowel Disease

Inflammatory Bowel Disease

United States
National Center for Research Resources (NCRR)
National Institute of Neurological Disorders and Stroke (NINDS); University...

Completed

Phase III Randomized, Double-Blind Study of Prednisone for Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy
National Center for Research Resources (NCRR)
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Phase I/II Study of High-Dose Acyclovir for Central Nervous System or Disseminated Neonatal Herpes Simplex Virus Infection

Herpes Simplex
National Center for Research Resources (NCRR)
Johns Hopkins University

Completed

Phase II Study of Sodium Phenylbutyrate, Sodium Benzoate, Sodium Phenylacetate, and Dietary Intervention for Urea Cycle Disorders

Amino Acid Metabolism, Inborn Errors
National Eye Institute (NEI)

Completed

Diabetic Retinopathy Vitrectomy Study (DRVS)

Diabetic Retinopathy | Vitreous Hemorrhage | Retinal Detachment
National Institute of Allergy and Infectious Diseases...
Janssen Pharmaceuticals

Completed

A Study of Letrazuril in the Treatment of AIDS-Related Diarrhea

HIV Infections | Cryptosporidiosis

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

A Third-Party Blinded, Placebo Controlled Comparative Study of AS-101 Administered Intravenously in HIV Positive Patients With Advanced Disease

HIV Infections

Brazil
Gilead Sciences

Completed

An Open-Label Study of the Safety and Efficacy of Cidofovir for the Treatment of Relapsing Cytomegalovirus Retinitis in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States
Hoechst Marion Roussel

Completed

A Study of MDL 28,574A in HIV-Infected Patients

HIV Infections

United States
National Center for Research Resources (NCRR)
University of Rochester

Completed

Pilot Compassionate Use Study of Thioctic Acid Treatment in Mitochondrial Myopathy

Mitochondrial Myopathy
National Center for Research Resources (NCRR)
Icahn School of Medicine at Mount Sinai

Completed

Diagnostic and Screening Study of Genetic Disorders

Metabolism, Inborn Errors | Leukodystrophy, Globoid Cell | Tay-Sachs Disease | Porphyria, Erythropoietic

United States
National Center for Research Resources (NCRR)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Ohio...

Completed

Study of Genetic Anomalies of Complement Related Proteins in Patients With IgA Glomerulonephritis

IGA Glomerulonephritis

United States
Glaxo Wellcome

Completed

A Study of Amprenavir in HIV-Infected Patients

HIV Infections

United States
R W Johnson Pharmaceutical Research Institute

Completed

A Double-Blind Study to Evaluate the Safety and Pharmacokinetics of L-Ofloxacin (RWJ 25213) in Subjects With HIV Infection

HIV Infections

United States
National Center for Research Resources (NCRR)
University of Vermont

Completed

Study of the Natural History and Genotype-Phenotype Correlations of Hereditary Hemorrhagic Telangiectasia Patients

Hereditary Hemorrhagic Telangiectasia
National Institute of Allergy and Infectious Diseases...

Completed

A Study to Evaluate the Impact of Stopping Treatment for the Prevention of Pneumonia in HIV-Positive Patients Receiving Anti-HIV Drugs Who Have Increased CD4 Cell Counts

HIV Infections | Pneumonia, Pneumocystis Carinii

United States, Puerto Rico
Hoffmann-La Roche

Completed

A Study of Saquinavir Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected Patients

HIV Infections

United States
Glaxo Wellcome

Completed

A Phase III, Randomized, Double-Blind, Multicentre Study to Evaluate the Safety and Efficacy of 1592U89 in Patients With AIDS Dementia Complex

HIV Infections | AIDS Dementia Complex

United States, Canada
Glaxo Wellcome

Completed

Treatment of AIDS and AIDS Related Complex. Part-1- Treatment of Patients With ARC (AZT Vs. Placebo)

HIV Infections

United States
Fairview University Medical Center

Completed

Study of Allogeneic Bone Marrow Transplantation Using Matched, Related Donors in Patients With Nonmalignant Hematologic Disorders

Neutropenia | Sickle Cell Anemia | Red-Cell Aplasia, Pure | Thalassemia Major

United States
Sandoz

Completed

A Multicenter Placebo-Controlled Dose Titration Study to Evaluate the Efficacy and Safety of Sandostatin (SMS 201-995) in the Treatment of Patients With Acquired Immunodeficiency Related Diarrhea

HIV Infections | Diarrhea

United States
Gilead Sciences

Completed

A Study on the Safety and Effectiveness of Adefovir Dipivoxil in Combination With Anti-HIV Therapy (HAART) in HIV-Positive Patients

HIV Infections

United States, United Kingdom, Germany, Canada, France
Chiron Corporation

Completed

A Phase I, Observer-Blind, Placebo-Controlled Study of the Chiron Vaccine HIV p24/MF59 Administered to Healthy HIV-Seronegative Adults

HIV Infections | HIV Seronegativity

United States
National Center for Research Resources (NCRR)
Urological Research Foundation

Completed

Follow-Up Study for Men Diagnosed With Prostate Cancer Through Participation in a Prostate Specific Antigen Screening Program

Prostate Cancer

United States
Hoffmann-La Roche

Completed

A Study of ddC in Patients With AIDS or Advanced AIDS-Related Complex (ARC) Who Have Not Had Success With Zidovudine (AZT)

HIV Infections

United States
National Center for Research Resources (NCRR)
University of North Carolina

Completed

Phase I Pilot Study of Ad5-CB-CFTR, an Adenovirus Vector Containing the Cystic Fibrosis Transmembrane Conductance Regulator Gene, in Patients With Cystic Fibrosis

Cystic Fibrosis
Eunice Kennedy Shriver National Institute of Child...
Nationwide Children's Hospital

Completed

Randomized Study of Succimer (Dimercaptosuccinic Acid) on Growth of Lead-Poisoned Children

Lead Poisoning
Pfizer

Completed

Phase I Study of the Clinical Pharmacology of Azithromycin in Buffy Coat of HIV-Infected Subjects.

HIV Infections | Bacterial Infections

United States
Sandoz

Completed

A Phase I/II Pilot Study of Simultaneously Administered Rhu GM-CSF ( CHO Cell ) and Azidothymidine ( AZT ) in Patients With Severe HIV Infection and Leukopenia: Pharmacokinetics and Feasibility

HIV Infections | Cytopenias

United States
Sandoz

Completed

A Phase I/II Trial to Assess the Safety and Tolerance of Escalating Doses of a Human Anti-Cytomegalovirus Monoclonal Antibody (SDZ MSL-109) in Patients With the Acquired Immunodeficiency Syndrome and CMV Retinitis

HIV Infections | Cytomegalovirus Retinitis

United States
National Center for Research Resources (NCRR)
Ohio State University

Completed

Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron Disease

Amyotrophic Lateral Sclerosis | Spinal Muscular Atrophy | Spinobulbar Muscular Atrophy
Ortho Pharmaceuticals

Completed

A Double-Blind, Placebo-Controlled Study With Open-Label Follow-Up To Determine the Safety and Efficacy of r-HuEPO in AIDS Patients With Anemia Induced by Their Disease and AZT Therapy

HIV Infections | Cytopenias

United States
National Center for Research Resources (NCRR)
University of Texas

Unknown

Phase I/II Study of Neuroendocrine Dysfunction in Patients With Closed Head Injuries

Brain Injury

United States
Lederle Laboratories

Completed

An Ascending, Single Oral Dose Pharmacokinetic Study of 3'-Deoxy-3'-Fluorothymidine (FLT) in Asymptomatic Human Immunodeficiency Virus (HIV)-Infected Subjects

HIV Infections

United States
Pfizer

Completed

A Study of Fluconazole in the Treatment of Cryptococcal Meningitis in Patients Who Have Not Had Success With Amphotericin B

HIV Infections | Meningitis, Cryptococcal

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I Randomized Dose/Formulation Comparison Study of SC-52151

HIV Infections

United States
National Center for Research Resources (NCRR)
Tulane University School of Medicine

Completed

Phase III Randomized Study of High Vs Standard Dose of Interferon Alfa for Chronic Hepatitis C

Hepatitis C
Otsuka America Pharmaceutical

Completed

A Study of Multiple Doses of Vesnarinone in Advanced HIV Disease

HIV Infections

United States

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