Search clinical trials for: First-Line chemotherapy

Total 12490 results

National Cancer Institute (NCI)

Completed

Phase II Neoadjuvant Trial of a Continuous Infusion of Paclitaxel Plus Cisplatin Followed by Chest Radiotherapy for Patients With Stage III Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung | Lung Neoplasms

United States
National Cancer Institute (NCI)

Completed

A Phase I Study of Irinotecan (CPT-11) Administered as a Prolonged Infusion in Adult Patients With Solid Tumors

Neoplasms

United States
National Cancer Institute (NCI)

Completed

Autologous T-Cell Transplantation and the Immunotherapy of Residual Disease in Breast Cancer: Pilot Study of Vaccine-Driven T-Cell Expansion in Patients Treated With Dose-Intensive Chemotherapy

Neoplasm Metastasis | Breast Neoplasm

United States
National Cancer Institute (NCI)

Completed

Pilot Study of a Double Isolation Perfusion Schedule Using Melphalan Alone for Intransit Melanoma or Unresectable Sarcoma of the Extremity

Melanoma | Sarcoma

United States
National Cancer Institute (NCI)

Completed

A Prospective, Randomized, Phase III Trial of FLAC (5-Fluorouracil, Leucovorin, Adriamycin, Cytoxan) Chemotherapy With GM-CSF (Granulocyte-Macrophage Colony-Stimulating Factor) Versus PIXY 321 in Advanced Breast Cancer

Sepsis | Hematologic Diseases | Breast Neoplasms | Neutropenia | Fever

United States
National Cancer Institute (NCI)

Completed

Effect of Preoperative Chemotherapy on Axillary Lymph Node Metastases in Stage II Breast Cancer: A Prospective Randomized Trial

Neoplasm Metastasis | Breast Neoplasm

United States
National Cancer Institute (NCI)

Completed

A Phase II Study of 5-Fluorouracil Administered as a One Hour Infusion in Combination With Calcium Leucovorin and Interferon Alpha-2A in Advanced Colorectal Cancer

Colorectal Neoplasms

United States
National Cancer Institute (NCI)

Completed

A Phase I Study of Taxol, Cisplatin, Cyclophosphamide and Granulocyte Colony-Stimulating Factor (G-CSF) in Previously Nontreated Ovarian Cancer Patients

Ovarian Neoplasms

United States
National Cancer Institute (NCI)

Completed

Osteosarcoma Study #2: A Randomized Trial of Pre-Surgical Chemotherapy vs. Immediate Surgery and Adjuvant Chemotherapy in the Treatment of Non-Metastatic Osteosarcoma. A Pediatric Oncology Group Phase III Study

Osteosarcoma

United States
National Cancer Institute (NCI)

Completed

Phase I Trial of FLAC (5-Fluorouracil, Leucovorin, Adriamycin, Cytoxan) Plus GM-CSF (Granulocyte-Macrophage Colony Stimulating Factor) Plus Dose Escalation of IL-3 (Interleukin-3) in Metastatic Breast Cancer

Breast Neoplasms | Neoplasm Metastasis

United States
National Cancer Institute (NCI)

Completed

A Pilot Trial of Sequential Chemotherapy With Antimetabolite Induction, High-Dose Alkylating Agent Consolidation With Peripheral Blood Progenitor Cell Support, and Intensification With Paclitaxel and Doxorubicin for Patients With High-Risk Breast Cancer

Breast Cancer | Breast Neoplasms

United States
National Institute of Allergy and Infectious Diseases...

Completed

Clinical Investigation of Infections Due to Leishmanial Parasites

Leishmaniasis | Leishmaniasis, Visceral

United States
National Cancer Institute (NCI)

Completed

Phase II Trial of a 96-Hour Continuous Infusion of Paclitaxel Followed by Cisplatin for Patients With Stage III/IV and Relapsed NSCLC

Carcinoma, Non-Small-Cell Lung | Lung Neoplasms

United States
National Institutes of Health Clinical Center (CC)

Completed

Comparison of Quality of Life in Patients Undergoing More Intensive Versus Less Intensive Chemotherapy and Radiation Preceding a Bone Marrow Transplant

Bone Marrow Transplantation

United States
Mackay Memorial Hospital

Unknown

Impaired Immunity in Patients With Cancer: Influence of Cancer Stage, Chemotherapy, and Cytomegalovirus Infection

Neoplasms

Taiwan
Amgen

Completed

Treatment for Patients With Non-Myeloid Malignancies Receiving Chemotherapy

Cancer | Non-Myeloid Malignancies
NEMA Research, Inc.

Completed

Evaluation of the Efficacy of Cesamet™ for the Treatment of Pain in Patients With Chemotherapy-Induced Neuropathy

Peripheral Neuropathy | Antineoplastic Combined Chemotherapy Protocols

United States
Kamuzu University of Health Sciences
British Society for Antimicrobial Chemotherapy

Completed

A Comparison of Gentian Violet (GV) Mouth Washes, Nystatin, and Ketoconazole Tabs in Treating Oropharyngeal Candidiasis

Candidiasis, Oral

Malawi
Genentech, Inc.

Completed

A Study to Evaluate Bevacizumab and Chemotherapy or Tarceva in Treating Recurrent or Refractory NSCLC (Non-Small Cell Lung Cancer)

Non-Small-Cell Lung Carcinoma | Neoplasm Recurrence, Local

United States
Medical University of Graz

Completed

Melanocytic Nevi in Children Under Chemotherapy

Nevus, Pigmented

Austria
National Center for Complementary and Integrative...

Completed

Ginger Control of Chemotherapy Induced Nausea and Vomiting

Nausea | Vomiting | Chemotherapy

United States, Puerto Rico
Hellenic Oncology Research Group
University Hospital of Crete

Completed

Randomized Phase III Trial Comparing Sequential Administration of FE75C Followed by Docetaxel Versus Paclitaxel as Adjuvant Chemotherapy in Axillary Lymph Node (+) Breast Cancer

Breast Cancer

Greece
Peking University
Fudan University; Capital Medical University

Unknown

Study of Oxaliplatin, Calcium Folinate, and 5-Fluorouracil as Neoadjuvant Chemotherapy for Resectable Advanced Gastric Cancer

Stomach Neoplasms | Gastric Cancer

China
Hospital of Navarra
Dr. Enrique Martínez López

Unknown

Study of 3D Radiotherapy With or Without Erlotinib (Tarceva®) in Patients With Localized Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

Spain
University of Michigan Rogel Cancer Center

Terminated

Study of Rituximab Plus High-Dose Chemotherapy Poor Prognosis Non-Hodgkin's Lymphoma

Lymphoma, Non-Hodgkin's

United States
National Cancer Center, Korea

Unknown

S-1 vs Capecitabine in the Elderly and/or Poor Performance Status Patients With Recurrent or Metastatic Gastric Cancer

Stomach Neoplasms

Korea, Republic of
National Cancer Center, Korea

Unknown

Phase II Study of Perioperative S-1 Plus Docetaxel in Patients With Localized Advanced Gastric Cancer

Stomach Neoplasms

Korea, Republic of
National Cancer Center, Korea

Unknown

Study of Continuous or Intermittent S-1 Combined With Oxaliplatin in Recurrent or Metastatic Gastric Carcinoma

Stomach Neoplasms

Korea, Republic of
Aptose Biosciences Inc.

Completed

A Study to Test the Effectiveness of Virulizin® Given in Combination With Standard Chemotherapy for Pancreatic Cancer

Pancreatic Cancer
Massachusetts General Hospital
Eli Lilly and Company; GlaxoSmithKline

Completed

Phase II Study of Modified Triple Doublet Therapy in Women With Newly Diagnosed Mullerian Carcinoma

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer

United States
Astellas Pharma Inc

Completed

LUCY: A Study for the Treatment of Non-Small Cell Lung Cancer (NSCLC) in Patients Previously Treated With Chemotherapy

Lung Cancer | Carcinoma, Non-Small Cell Lung | Cancer of Lung | Non-Small Cell Lung Carcinoma | Cancer of the Lung

Germany, Czech Republic, Netherlands
Dana-Farber Cancer Institute
Boston Children's Hospital

Terminated

Treatment of Childhood Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia

United States, Puerto Rico, Canada
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Bazedoxifene/Conjugated Estrogen Combinations in Vasomotor Symptoms Associated With Menopause

Vaginal Atrophy

United States
National Institute of Arthritis and Musculoskeletal...
University of Pittsburgh; Genzyme, a Sanofi Company; Amgen

Terminated

Safety and Value of Self Bone Marrow Transplants Following Chemotherapy in Scleroderma Patients

Systemic Sclerosis | Scleroderma

United States
Amgen

Completed

Treatment for Patients With Non-Small Cell Lung Cancer Who Developed Anemia Due to Chemotherapy

Anemia | Non-Small Cell Lung Cancer
Maxygen Holdings Ltd.
Parexel; Maxygen ApS; Maxygen, Inc.

Unknown

Evaluation of Maxy-G34 in Breast Cancer Patients Treated With TAC (Docetaxel, Adriamycin, Cyclophosphamide) Chemotherapy

Breast Cancer | Chemotherapy-Induced Neutropenia

Poland, Romania, Russian Federation, Ukraine
Amgen

Completed

Treatment for Patients Suffering From Anemia Due to Chemotherapy

Breast Cancer | Anemia
Cell Genesys

Completed

Vaccination in the Peripheral Stem Cell Transplant Setting for Multiple Myeloma

Multiple Myeloma

United States
Amgen

Completed

Treatment for Patients With Gynecological Malignancies Who Suffer From Anemia Due to Chemotherapy

Genital Neoplasms, Female | Anemia | Gynecological Malignancies
Novartis

Completed

Safety and Tolerability of Rivastigmine With Add-on Memantine in Patients With Probable Alzheimer's Disease

Alzheimer's Disease

United States
Hadassah Medical Organization

Unknown

Fertility Preservation by Ovarian and Oocyte Cryopreservation (HFPP)

Female Patients Aged 5-35 Prior to Systemic Chemotherapy | With Significant Risk of Ovarian Toxicity

Israel
Unither Pharmaceuticals

Terminated

Study of Ovarex® (Oregovomab) MAb With Front-Line Chemotherapy for Ovarian Cancer Treatment

Ovarian Cancer
AstraZeneca

Completed

A Phase 2 Study of Tomudex & Iressa as Second Line Chemotherapy in Subjects With Colorectal Carcinoma

Colorectal Cancer

Spain
Unither Pharmaceuticals

Terminated

Multicenter Clinical Trial of Intravenous OvaRex MAb-B43.13 as Post-Chemotherapy Consolidation for Ovarian Carcinoma

Ovarian Neoplasms

Canada, United States
University of Washington
Sanofi

Completed

Immunotherapy After Chemotherapy for Patients With Hormone Refractory Metastatic Prostate Cancer

Prostate Cancer

United States
Keio University

Terminated

Safety and Efficacy Study of Salvage Chemotherapy (R-ESHAP) to Treat Relapsed and Refractory Aggressive Non-Hodgkin's Lymphoma

Lymphoma, Non-Hodgkin

Japan
Geriatric Oncology Consortium
Tibotec Pharmaceutical Limited

Terminated

Pegylated Liposomal Doxorubicin Containing Chemotherapy in the Treatment of Older Non-Hodgkin's Lymphoma Patients

Non-Hodgkin's Lymphoma

United States
Ministry of Scientific Research and Information...

Terminated

RCT on the Combined Modality Treatment of Squamous Cell Carcinoma of the Esophagus

Esophageal Neoplasms | Squamous Cell Cancer

Poland
Czech Lymphoma Study Group
Hoffmann-La Roche; Ministry of Health, Czech Republic

Completed

R-MegaCHOP-ESHAP-BEAM in Patients With High-Risk Aggressive B-Cell Lymphomas (R-MCEB)

Diffuse Large B-Cell Lymphoma. | Primary Mediastinal B-Cell Lymphoma | Follicular Lymphoma Grade III

Czech Republic
University Hospital, Limoges
Groupe Français de Pneumologie Cancérologie (GFPC)

Completed

Study of an Early Change of a Chemotherapeutic Doublet Versus Four Cycles of Chemotherapy in Advanced Non Small Cell Lung Cancer

Non Small Cell Lung Carcinoma

France

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