Search clinical trials for: cytotoxic chemotherapy

Total 12633 results

Rigshospitalet, Denmark

Unknown

Neoadjuvant Chemotherapy Plus/Minus Surgery in Non-Small-Cell Lung Cancer (NSCLC) Stage IIIA/N2

Non-Small Cell Lung Cancer

Denmark
Johannes Gutenberg University Mainz

Completed

Efficacy of Irinotecan and Capecitabine Versus(vs) Cisplatin and Capecitabine in Patients With Esophago-Gastric Cancer

Gastric Cancer

Germany
Pharmexa A/S
Syneos Health; ICON Clinical Research; ORION Clinical Services; CIRION Central... and other collaborators

Terminated

GV1001 and Gemcitabine in Sequential Combination to Gemcitabine Monotherapy in Pancreatic Cancer

Advanced Unresectable Pancreatic Cancer

United States, Spain, Australia, Netherlands, Belgium, Denmark, France, Ireland, Italy, Norway, Poland, Sweden
Amgen

Completed

A Study of Peripheral Blood Progenitor Cell (PBPC) Mobilisation by Chemotherapy With Pegfilgrastim or Filgrastim in Subjects With Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma
Universita degli Studi di Catania

Completed

Antibiotic Therapy is Not Necessary to Implant Totally Implantable Venous Access Devices: Randomized Prospective Study (TIVAD)

Infections
ARCA Biopharma, Inc.

Suspended

Safety Study of Recombinant NAPc2 to Prevent Tumor Progression and Metastases in Metastatic Colon Cancer

Colon Cancer

United States
Prostrakan Pharmaceuticals

Completed

To Study the Safety and Effectiveness of a Granisetron Patch to Treat Chemotherapy-Induced Nausea and Vomiting (CINV)

Chemotherapy-Induced Nausea and Vomiting
Hospital JP Garrahan

Completed

Phase I Trial of Periocular Topotecan in Retinoblastoma

Retinoblastoma

Argentina
Memorial Sloan Kettering Cancer Center

Completed

Ph I:Bevacizumab + Chemotherapy in Pts w/Malig Pleural Effusion Due to Adv NSCLC

Carcinoma, Non-Small-Cell Lung

United States
Tehran University of Medical Sciences
Hoffmann-La Roche

Completed

Rituximab for the Treatment of Severe Ocular Manifestations of Behcet's Disease

Behcet's Syndrome

Iran, Islamic Republic of
Xijing Hospital

Completed

An Efficacy and Safety Study of Palonosetron in Preventing Chemotherapy-Induced Nausea and Vomiting (CINV) in the Chinese Cancer Patients

Chemotherapy-Induced Nausea and Vomiting

China
Heidelberg University
University Hospital Muenster; University Hospital, Saarland; Lung Clinic Hemer; Kreiskrankenhaus Diekholzen and other collaborators

Completed

Preoperative Twice Daily Chemoradiation in Addition to Chemotherapy Prior to Surgery in Stage III Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer
Fudan University

Unknown

An All-Oral Combination of Capecitabine and Cyclophosphamide in Patients With Metastatic Breast Cancer (MBC)

Breast Cancer

China
St. Jude Children's Research Hospital

Completed

Recombinant Human Thrombopoietin in Children Receiving Ifosfamide, Carboplatin, and Etoposide Chemotherapy

Osteosarcoma | Neuroblastoma | Rhabdomyosarcoma | Hepatic Cancer | Germ Cell Tumors

United States
US Department of Veterans Affairs

Completed

Chemotherapy, Hormone Therapy, and Surgery to Remove the Prostate Gland in Patients With High Risk Prostate Cancer

Prostate Cancer

United States
Solvay Pharmaceuticals

Completed

Dronabinol Versus Standard Ondansetron Antiemetic Therapy in Preventing Delayed-Onset Chemotherapy-Induced Nausea and Vomiting

Chemotherapy Induced Nausea and Vomiting

United States
Sanofi

Terminated

Docetaxel + Doxorubicin as Neoadjuvant Chemotherapy in Patients With Breast Cancer

Ductal Carcinoma
Kanisa Pharmaceuticals

Completed

Zosuquidar in Combination With Daunorubicin and Cytarabine in Patients Ages 55-75 With Newly Diagnosed Acute Myeloid Leukemia (AML)

Leukemia, Myeloid
Pfizer

Completed

Intravenous Edotecarin in Patients With Advanced Gastric Cancer That Has Progressed or Recurred After Chemotherapy

Stomach Neoplasms

Spain, Belgium, Taiwan, France, United Kingdom
Kanisa Pharmaceuticals

Completed

A Trial of Gemtuzumab Ozogamicin (GO) in Combination With Zosuquidar in Patients With CD33 Positive Acute Myeloid Leukemia

Leukemia, Myeloid
Genitope Corporation

Terminated

Personalized Active Immunotherapy (Vaccine Therapy) and Sargramostim Given After Standard of Care Treatment With Rituximab and Chemotherapy for Initial Treatment With Lymphoma

Non-Hodgkin's Lymphoma

United States
AZ-VUB
Sanofi

Unknown

Concurrent Helical Tomotherapy With Chemotherapy in Unresectable Stage III Non-Small Cell Lung Cancer (NSCLC)

Non-Small-Cell Lung Carcinoma

Belgium
Gachon University Gil Medical Center

Unknown

Topotecan for Irinotecan-Refractory SCLC

Lung Cancer | Refractory to Chemotherapy

Korea, Republic of
Peking University People's Hospital
Peking University; Sanofi

Unknown

Phase 3 Study of Surgery Combined With Neoadjuvant Chemotherapy(XELOX) in Colorectal Cancer With Resectable Liver Metastasis

Colorectal Cancer | Resectable Liver Metastasis

China
Eisai Inc.

Completed

Study of ONTAK (Denileukin Diftitox) in Cutaneous T-Cell Lymphoma (CTCL) Patients

Lymphoma, T-Cell, Cutaneous | Mycosis Fungoides | Sezary Syndrome

Germany, Canada, United Kingdom, Austria, Russian Federation, United States, Australia, Poland, Switzerland, Netherlands
Eisai Inc.

Completed

Study of ONTAK (Denileukin Diftitox) in Previously Treated Cutaneous T-Cell Lymphoma Patients

Lymphoma, T-Cell, Cutaneous | Mycosis Fungoides | Sezary Syndrome

Germany, Canada, Australia, United Kingdom, Austria, Russian Federation, United States, Poland, Switzerland
National Institute of Allergy and Infectious Diseases...

Completed

Steroids and Methotrexate to Treat Systemic Vasculitis

Inflammation | Vasculitis | Wegener's Granulomatosis

United States
National Cancer Institute (NCI)

Completed

A Pilot Study for the Treatment of Patients With Metastatic and High Risk Sarcomas and Primitive Neuroectodermal Tumors

Sarcoma | Neuroepithelioma | Osteosarcoma | Neuroectodermal Tumor, Primitive | Sarcoma, Ewing's

United States
National Cancer Institute (NCI)

Completed

A Study of Combination Chemotherapy and Surgical Resection in the Treatment of Adrenocortical Carcinoma: Continuous Infusion Doxorubicin, Vincristine and Etoposide With Daily Mitotane Before and After Surgical Resection

Adrenal Cortical Carcinoma

United States
National Cancer Institute (NCI)

Completed

A Randomized Study of the Effect of Adjuvant Chemotherapy With Doxorubicin and Ifosfamide With Mesna in the Treatment of High-Grade Adult Extremity Soft Tissue Sarcoma

Sarcoma

United States
National Cancer Institute (NCI)

Completed

Phase I Study of Continuous Hyperthermic Peritoneal Perfusion (CHPP) With Escalating Dose I.P. Platinum for Gastrointestinal Peritoneal Carcinomatosis

Stomach Neoplasms | Peritoneal Neoplasms

United States
National Cancer Institute (NCI)

Completed

The Role of Multi-Modality Therapy for the Treatment of High-Grade Soft Tissue Sarcomas of the Extremities

Sarcoma

United States
National Institute of Diabetes and Digestive and...

Completed

Combination Chemotherapy in Patients With Zollinger-Ellison Syndrome and Tumors of the Pancreas

Neoplasm Metastasis | Zollinger Ellison Syndrome | Islet Cell Adenoma

United States
National Cancer Institute (NCI)

Completed

A Phase I Trial Using Suramin to Treat Superficial Transitional Cell Carcinoma of the Bladder

Carcinoma, Transitional Cell | Bladder Neoplasms

United States
National Cancer Institute (NCI)

Completed

A Phase I Study of Infusional Chemotherapy With the P-Glycoprotein Antagonist PSC 833

Lymphoma | Breast Cancer | Neoplasm Metastasis | Ovarian Cancer | Kidney Neoplasm

United States
National Institute of Arthritis and Musculoskeletal...

Completed

Methimazole to Treat Polymyositis and Dermatomyositis

Dermatomyositis | Polymyositis

United States
National Cancer Institute (NCI)

Completed

A Pilot Trial of AC (Adriamycin, Cyclophosphamide) Chemotherapy With G-CSF (Granulocyte Colony-Stimulating Factor) Followed by Infusional Taxol (Paclitaxel) as Adjuvant Treatment for High Risk Stage II and Stage III Breast Cancer Patients

Breast Cancer | Breast Neoplasms

United States
National Institute of Allergy and Infectious Diseases...

Completed

Stem Cell Transplant Following Low-Intensity Chemotherapy to Treat Chronic Granulomatous Disease

Chronic Granulomatous Disease

United States
National Cancer Institute (NCI)

Completed

Feasibility Study of Interleukin 1-Alpha With Ifosfamide, CBDCA, and Etoposide With Autologous Bone Marrow Transplant in Metastatic Carcinoma and Lymphoma

Lymphoma | Testicular Neoplasms | Breast Neoplasms | Neoplasm Metastasis

United States
National Cancer Institute (NCI)

Completed

A Pilot Study of Non-Hodgkin's Lymphoma: Chemotherapy and Blood Levels of Organochlorines

HIV Infections | Lymphoma, Non-Hodgkin | Lymphoma, AIDS-Related

United States
National Cancer Institute (NCI)

Completed

Combination Chemotherapy (FLAC) Combined With Granulocyte-Macrophage Colony Stimulating Factor in Locally Advanced and Metastatic Breast Cancer

Breast Cancer | Breast Neoplasms

United States
National Cancer Institute (NCI)

Completed

Phase II Neoadjuvant Trial of a Continuous Infusion of Paclitaxel Plus Cisplatin Followed by Chest Radiotherapy for Patients With Stage III Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung | Lung Neoplasms

United States
National Cancer Institute (NCI)

Completed

A Phase I Study of Irinotecan (CPT-11) Administered as a Prolonged Infusion in Adult Patients With Solid Tumors

Neoplasms

United States
National Cancer Institute (NCI)

Completed

Autologous T-Cell Transplantation and the Immunotherapy of Residual Disease in Breast Cancer: Pilot Study of Vaccine-Driven T-Cell Expansion in Patients Treated With Dose-Intensive Chemotherapy

Neoplasm Metastasis | Breast Neoplasm

United States
National Cancer Institute (NCI)

Completed

Combination Drug Treatment of Pediatric HIV Infection

HIV Infection

United States
National Cancer Institute (NCI)

Completed

Pilot Study of a Double Isolation Perfusion Schedule Using Melphalan Alone for Intransit Melanoma or Unresectable Sarcoma of the Extremity

Melanoma | Sarcoma

United States
National Cancer Institute (NCI)

Completed

A Prospective, Randomized, Phase III Trial of FLAC (5-Fluorouracil, Leucovorin, Adriamycin, Cytoxan) Chemotherapy With GM-CSF (Granulocyte-Macrophage Colony-Stimulating Factor) Versus PIXY 321 in Advanced Breast Cancer

Sepsis | Hematologic Diseases | Breast Neoplasms | Neutropenia | Fever

United States
National Cancer Institute (NCI)

Completed

Effect of Preoperative Chemotherapy on Axillary Lymph Node Metastases in Stage II Breast Cancer: A Prospective Randomized Trial

Neoplasm Metastasis | Breast Neoplasm

United States
National Cancer Institute (NCI)

Completed

A Phase II Study of 5-Fluorouracil Administered as a One Hour Infusion in Combination With Calcium Leucovorin and Interferon Alpha-2A in Advanced Colorectal Cancer

Colorectal Neoplasms

United States
National Cancer Institute (NCI)

Completed

Osteosarcoma Study #2: A Randomized Trial of Pre-Surgical Chemotherapy vs. Immediate Surgery and Adjuvant Chemotherapy in the Treatment of Non-Metastatic Osteosarcoma. A Pediatric Oncology Group Phase III Study

Osteosarcoma

United States

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