Clinical Trials Sponsored by Mereo BioPharma

Total 1409 results

Lyvgen Biopharma Holdings Limited
Merck Sharp & Dohme LLC

Recruiting

Phase 1 Trial of LVGN6051 as Single Agent and in Combination With Keytruda (Pembrolizumab) in Advanced or Metastatic Malignancy

Cancer

United States
HighTide Biopharma Pty Ltd
Shenzhen HighTide Biopharmaceutical Ltd.

Completed

A Phase 2 Study of Berberine Ursodeoxycholate (HTD1801) in Patients With Type 2 Diabetes Inadequately Controlled With Diet and Exercise

Type 2 Diabetes Mellitus

China
Food and Drug Administration (FDA)
BioPharma Services USA

Completed

Bioequivalence Study of Tacrolimus in Healthy Volunteers

Healthy Volunteers

United States
Weill Medical College of Cornell University
POINT Biopharma

Suspended

Phase I/II 225Ac-J591 Plus 177Lu-PSMA-I&T for Progressive Metastatic Castration Resistant Prostate Cancer

Prostate Cancer

United States
Cytosite Biopharma Inc.
University of Alabama at Birmingham

Completed

Study to Evaluate the Safety and Dosimetry of [68Ga]-NOTA-hGZP (CSB-111) PET Imaging in Healthy Human Volunteers.

Healthy Volunteers

United States
Hospital San Jose Tec de Monterrey
Inosan Biopharma

Completed

Safety and Efficacy of Anti-SARS-CoV-2 Equine Antibody F(ab')2 Fragments (INOSARS) for Adult Patients With Mild COVID-19

COVID-19

Mexico
Renmin Hospital of Wuhan University
Ansun Biopharma, Inc.

Completed

DAS181 for Severe COVID-19: Compassionate Use

COVID-19

China
Seoul National University Hospital
HanAll BioPharma Co., Ltd.

Unknown

Changes in Body Composition With Patients Under Androgen Deprivation Therapy

Sarcopenia | Prostate Cancer

Korea, Republic of
UCB Biopharma S.P.R.L.
PRA Health Sciences

Completed

Evaluating the Effectiveness of Neupro® (Rotigotine) and L-dopa Combination Therapy in Patients With Parkinson's Disease (NEUPART)

Idiopathic Parkinson's Disease

Germany, France, Italy, Spain, United Kingdom
Arbutus Biopharma Corporation
United States Department of Defense

Terminated

Safety, Tolerability and Pharmacokinetic First in Human (FIH) Study for Intravenous (IV) TKM-100802

Ebola Virus Infection

United States
Ansun Biopharma, Inc.
National Institutes of Health (NIH)

Completed

Randomized, Double-blind, Placebo Controlled Phase II Study to Examine the Effects of DAS181 in Healthy Adult Subjects With Laboratory Confirmed Influenza

Influenza

United States
Green Cross Corporation
Quintiles, Inc.

Completed

A Study to Assess Safety, Tolerability, and Pharmacokinetics of Orally Administered GCC4401C in Healthy Volunteers

Healthy Male

United States
Memorial Sloan Kettering Cancer Center
Ambrilia Biopharma, Inc.

Completed

Dose-Seeking Trial of PCK3145 in Asymptomatic, Castrate Metastatic Prostate Cancer Patients.

Prostate Cancer

United States
Chang Gung Memorial Hospital
TTY Biopharm

Completed

A Dose Titration Study of Fentanyl Buccal Soluble Film for Breakthrough Cancer Pain in Taiwan

Breakthrough Cancer Pain

Taiwan
KGK Science Inc.
Boston Biopharm, Inc.

Completed

A Study to Compare the Pharmacokinetic Profile of a Proprietary Curcumin Forumulation to a Comparator Curcumin Product (15PCHB)

Healthy

Canada
Aimei Vacin BioPharm (Zhejiang) Co., Ltd.

Not yet recruiting

A Study of the ACYW135 Meningococcal Polysaccharide Conjugate Vaccine

Meningococcal Meningitis

China
TTY Biopharm
Chang Gung Memorial Hospital

Completed

TS-1 in Combination With Calcium Folinate in Patients With Heavily Pre-treated mCRC

Metastatic Colorectal Cancer

Taiwan
National Taiwan University Hospital
TTY Biopharm

Terminated

Phase I Study of TS-1 With Concurrent Radiotherapy to Treat Pancreatic Cancer (SR-GS)

Metastatic Pancreatic Cancer

Taiwan
Lingli Dong
Shenzhen Pregene Biopharma Co., Ltd.

Recruiting

Refractory ANCA Associated Vasculitis and Lupus Nephritis Treated With BCMA-targeting CAR-T Cells

Lupus Nephritis | ANCA Associated Vasculitis

China
Lambda Therapeutic Research Ltd.
Intas Pharmaceutical Limited (Biopharma Division)

Recruiting

Denosumab Biosimilar Injection in Post Menopausal Women With Osteoporosis

Osteoporosis, Postmenopausal

India
Walvax Biotechnology Co., Ltd.
Shanghai RNACure Biopharma Co., Ltd.

Not yet recruiting

A Phase 1b Trial to Evaluate the Safety and Immunogenicity of a SARS-CoV-2 mRNA Chimera Vaccine Against COVID-19

COVID-19
Zenith Epigenetics
Astellas Pharma Inc; Newsoara Biopharma Co., Ltd.

Recruiting

ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer

Metastatic Castration-Resistant Prostate Cancer

United States, China
Adlai Nortye Biopharma Co., Ltd.
Merck Sharp & Dohme LLC

Active, not recruiting

AN0025 and Pembrolizumab Combination in Advanced Solid Tumors

Cervical Cancer | Triple-negative Breast Cancer | NSCLC, Squamous or Non-Squamous | Urothelial Carcinoma of the Bladder | Microsatellite Stable (MSS) Colorectal Cancer (CRC)

United States, France
Jason J. Luke, MD
Array BioPharma

Active, not recruiting

Study of ARRY-614 Plus Either Nivolumab or Nivolumab+Ipilimumab

Melanoma | Renal Cell Carcinoma | Solid Tumor | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma

United States
Weill Medical College of Cornell University
Oncolys BioPharma Inc

Completed

Phase 2 Study of Telomelysin (OBP-301) in Combination With Pembrolizumab in Esophagogastric Adenocarcinoma

Esophagogastric Adenocarcinoma

United States
Qpex Biopharma, Inc.
Biomedical Advanced Research and Development Authority

Completed

Phase 1 Oral QPX7831 SAD and MAD in Healthy Adults

Bacterial Infections

Australia, United States
Qpex Biopharma, Inc.
Biomedical Advanced Research and Development Authority

Completed

P1 Single and Multiple Ascending Dose (SAD/MAD) Study of IV QPX7728 Alone and Combined With QPX2014 in NHV

Bacterial Infections

Australia, United States
Qpex Biopharma, Inc.
Biomedical Advanced Research and Development Authority

Completed

Phase 1 Study of Oral QPX2015 in Healthy Adult Subjects

Bacterial Infections

Australia
Connect Biopharma Australia Pty Ltd

Completed

A Study to Investigate the Effects of CBP-307 on the Heart Rate-corrected QT Interval (QTc) in Healthy Subjects

Autoimmune Diseases

Australia, United States
Advagene Biopharma Co. Ltd.
Taipei Medical University; Clinipace Worldwide

Completed

Tolerability and Potential Efficacy of LTh(αΚ) in Subjects With Allergic Rhinitis

Allergic Rhinitis

Taiwan
Hangzhou Adcoris Biopharmacy Co., Ltd

Not yet recruiting

Study of ACR246 in Advanced Solid Tumors

Advanced Solid Tumors
Children's Hospital of Philadelphia
ApoPharma

Approved for marketing

Compassionate Use of Deferiprone for Patients With Thalassemia and Iron-Induced Heart Disease

Iron Overload

United States
Seoul National University Bundang Hospital
Samyang BioPharm

Recruiting

Lenalidomide Maintenance Treatment in Patients With Primary Central Nervous System Lymphoma (PCNSL-LEM)

Central Nervous System Lymphoma

Korea, Republic of
Taipei Medical University Hospital
Pfizer; TTY Biopharm

Unknown

Salvage Therapy With Sunitinib,Docetaxel and Platinum on Metastatic or Unresectable Non Small Cell Lung Cancer

Non Small Cell Lung Cancer

Taiwan
Estrella Biopharma, Inc.
Eureka Therapeutics Inc.

Not yet recruiting

T-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL) (STARLIGHT-1)

Lymphoma | Lymphoma, Non-Hodgkin | Non-Hodgkin's Lymphoma | Non-Hodgkin Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Refractory Non-Hodgkin Lymphoma | High-grade B-cell Lymphoma | CNS Lymphoma | Lymphomas Non-Hodgkin's B-Cell | Relapsed Non-Hodgkin Lymphoma | Lymphoma, Non-Hodgkins | Large B-Cell Lymphoma and other conditions
Walvax Biotechnology Co., Ltd.
Shanghai RNACure Biopharma Co., Ltd.

Not yet recruiting

A Phase 1a Trial to Evaluate the Safety and Immunogenicity of a SARS-CoV-2 mRNA Chimera Vaccine Against COVID-19

COVID-19
Green Cross Corporation
Atlantic Research Group

Recruiting

Study of Immune Globulin Intravenous (Human) GC5107 in Pediatric Subjects With Primary Humoral Immunodeficiency

Primary Immune Deficiency

United States
Jonsson Comprehensive Cancer Center
Bristol-Myers Squibb; Array BioPharma

Recruiting

Binimetinib and Nivolumab for the Treatment of Locally Advanced Unresectable or Metastatic BRAF V600 Wildtype Melanoma

Metastatic Cutaneous Melanoma | Unresectable Cutaneous Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Pathologic Stage IIID Cutaneous Melanoma AJCC v8 | Pathologic Stage III Cutaneous... and other conditions

United States
SmartNuclide Biopharma
The First Affiliated Hospital of Soochow University

Completed

A PET Imaging Agent to Assess the Level of Tumor Tissue-infiltrating CD8 + T Cells in Patients With Solid Tumors

Solid Tumor

China
Weill Medical College of Cornell University
Oncolys BioPharma Inc

Terminated

Phase 2 Study of OBP-301 (Telomelysin™) in Combination With Pembrolizumab and SBRT in Patients With HNSCC With Inoperable, Recurrent or Progressive Disease

Head and Neck Squamous Cell Carcinoma With Inoperable Recurrent or Progressive Disease

United States
Qpex Biopharma, Inc.
Biomedical Advanced Research and Development Authority

Completed

SAD/MAD Safety and PK Study of QPX9003 (Novel Polymyxin) in Normal Healthy Volunteers (QPX9003)

Bacterial Infections

United States
Qpex Biopharma, Inc.
Biomedical Advanced Research and Development Authority

Completed

Drug-Drug Interaction Study of IV QPX2014 Combined With QPX7728 in Healthy Adult Subjects

Bacterial Infections

United States
Green Cross Corporation
Dream CIS, Inc.

Completed

A Study to Investigate the Safety, Tolerability, PK and PD of MG1113 in Healthy Subjects and Hemophilia Patients

Hemophilia

Korea, Republic of
Green Cross Corporation
Atlantic Research Group

Completed

Phase 3 Study of Immune Globulin Intravenous (Human)IVIG-SN™ in Subjects With Primary Immunodeficiency

Immunologic Deficiency Syndrome

United States, Canada
Green Cross Corporation
Atlantic Research Group

Unknown

Safety and Efficacy Extension Study of GreenGene™ F in Previously Treated Patients Diagnosed With Severe Hemophilia A

Hemophilia A

United States
Lytix Biopharma AS
Karolinska University Hospital; Oslo University Hospital

Completed

Dose-escalation Study of LTX-315 in Patients With a Transdermally Accessible Tumour

Cancer With Transdermal Accessible Tumour

Sweden, Norway
Kiromic BioPharma Inc.
Statistics & Data Corporation; Stiris Research Inc

Recruiting

Safety Study for a Gamma Delta T Cell Product Used With Low Dose Radiotherapy in Patients With Stage 4 Metastatic NSCLC

Carcinoma, Non-Small-Cell Lung

United States
SmartNuclide Biopharma
The First Affiliated Hospital of Soochow University

Recruiting

[68Ga]Ga-NOTA-SNA002 (PD-L1 PET Tracer) for PET/CT in Patients With Solid Tumors

Solid Tumor | Positron-Emission Tomography(PET)

China
Principia Biopharma, a Sanofi Company
Massachusetts General Hospital

Active, not recruiting

Open Label Two-Arm Study to Evaluate Rilzabrutinib in IgG4-Related Disease Patients

Immunoglobulin G4 Related Disease

United States, Canada, France, Italy, Spain
Seoul National University Hospital
GC Biopharma Corp; Severance Hospital

Completed

IVIG/Rituximab vs Rituximab in Kidney Transplant With de Novo Donor-specific Antibodies

Renal Transplant

Korea, Republic of

Clinical Trials Sponsored by Mereo BioPharma

Sponsors and Collaborators

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CROs in Georgia

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